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Volumn 66, Issue 3, 2009, Pages 292-297

Targeted reduction of KLF6-SV1 restores chemotherapy sensitivity in resistant lung adenocarcinoma

Author keywords

Chemotherapy resistance; Lung cancer; Mouse models; Oncogene

Indexed keywords

CASPASE 3; CASPASE 8; CISPLATIN; KRUPPEL LIKE FACTOR 6; KRUPPEL LIKE FACTOR 6 SPLICE VARIANT 1; PROTEIN MCL 1; PROTEIN NOXA; SMALL INTERFERING RNA; UNCLASSIFIED DRUG;

EID: 68949206913     PISSN: 01695002     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.lungcan.2009.02.014     Document Type: Article
Times cited : (24)

References (21)
  • 2
    • 17044393041 scopus 로고    scopus 로고
    • Adjuvant chemotherapy of lung cancer: methodologic issues and therapeutic advances
    • Strauss G.M. Adjuvant chemotherapy of lung cancer: methodologic issues and therapeutic advances. Hematol Oncol Clin North Am 19 (2005) 263-281
    • (2005) Hematol Oncol Clin North Am , vol.19 , pp. 263-281
    • Strauss, G.M.1
  • 3
    • 19844364466 scopus 로고    scopus 로고
    • Multimodality therapy for stage III non small-cell lung cancer
    • Farray D., Mirkovic N., and Albain K.S. Multimodality therapy for stage III non small-cell lung cancer. J Clin Oncol 23 (2005) 3257-3269
    • (2005) J Clin Oncol , vol.23 , pp. 3257-3269
    • Farray, D.1    Mirkovic, N.2    Albain, K.S.3
  • 4
    • 34249819963 scopus 로고    scopus 로고
    • ERCC1 as a risk stratifier in platinum-based chemotherapy for nonsmall-cell lung cancer
    • Olaussen K.A., Mountzios G., and Soria J.C. ERCC1 as a risk stratifier in platinum-based chemotherapy for nonsmall-cell lung cancer. Curr Opin Pulm 13 (2007) 284-289
    • (2007) Curr Opin Pulm , vol.13 , pp. 284-289
    • Olaussen, K.A.1    Mountzios, G.2    Soria, J.C.3
  • 5
    • 33745852782 scopus 로고    scopus 로고
    • Modulation of multidrug resistance efflux pump activity to overcome chemoresistance in cancer
    • Modok S., Mellor H.R., and Callaghan R. Modulation of multidrug resistance efflux pump activity to overcome chemoresistance in cancer. Curr Opin Pharmacol 6 (2006) 350-354
    • (2006) Curr Opin Pharmacol , vol.6 , pp. 350-354
    • Modok, S.1    Mellor, H.R.2    Callaghan, R.3
  • 6
    • 18244389734 scopus 로고    scopus 로고
    • KLF6, a candidate tumor suppressor gene mutated in prostate cancer
    • Narla G., Heath K.E., Reeves H.L., et al. KLF6, a candidate tumor suppressor gene mutated in prostate cancer. Science 294 (2001) 2563-2566
    • (2001) Science , vol.294 , pp. 2563-2566
    • Narla, G.1    Heath, K.E.2    Reeves, H.L.3
  • 7
    • 11144357280 scopus 로고    scopus 로고
    • Kruppel-like factor 6 (KLF6) is a tumor-suppressor gene frequently inactivated in colorectal cancer
    • Reeves H.L., Narla G., Ogunbiyi O., et al. Kruppel-like factor 6 (KLF6) is a tumor-suppressor gene frequently inactivated in colorectal cancer. Gastroenterology 126 (2004) 1090-1103
    • (2004) Gastroenterology , vol.126 , pp. 1090-1103
    • Reeves, H.L.1    Narla, G.2    Ogunbiyi, O.3
  • 8
    • 7044246221 scopus 로고    scopus 로고
    • Frequent inactivation of the tumor suppressor kruppel-like factor 6 (KLF6) in hepatocellular carcinoma
    • Kremer-Tal S., Reeves H.L., Narla G., et al. Frequent inactivation of the tumor suppressor kruppel-like factor 6 (KLF6) in hepatocellular carcinoma. Hepatology 40 (2004) 1047-1052
    • (2004) Hepatology , vol.40 , pp. 1047-1052
    • Kremer-Tal, S.1    Reeves, H.L.2    Narla, G.3
  • 9
    • 22744454819 scopus 로고    scopus 로고
    • Genetic alterations of the KLF6 gene in gastric cancer
    • Cho Y.G., Kim C.J., Park C.H., et al. Genetic alterations of the KLF6 gene in gastric cancer. Oncogene 24 (2005) 4588-4590
    • (2005) Oncogene , vol.24 , pp. 4588-4590
    • Cho, Y.G.1    Kim, C.J.2    Park, C.H.3
  • 10
    • 33745725772 scopus 로고    scopus 로고
    • Roles of KLF6 and KLF6-SV1 in ovarian cancer progression and intraperitoneal dissemination
    • DiFeo A., Narla G., Hirshfeld J., et al. Roles of KLF6 and KLF6-SV1 in ovarian cancer progression and intraperitoneal dissemination. Clin Cancer Res 12 (2006) 3730-3739
    • (2006) Clin Cancer Res , vol.12 , pp. 3730-3739
    • DiFeo, A.1    Narla, G.2    Hirshfeld, J.3
  • 11
    • 0038174752 scopus 로고    scopus 로고
    • KLF6, a putative tumor suppressor gene, is mutated in astrocytic gliomas
    • Jeng Y.M., and Hsu H.C. KLF6, a putative tumor suppressor gene, is mutated in astrocytic gliomas. Int J Cancer 105 (2003) 625-629
    • (2003) Int J Cancer , vol.105 , pp. 625-629
    • Jeng, Y.M.1    Hsu, H.C.2
  • 12
    • 10744224693 scopus 로고    scopus 로고
    • Differentially expressed genes in nonsmall cell lung cancer: expression profiling of cancer-related genes in squamous cell lung cancer
    • Kettunen E., Anttila S., Seppanen J.K., et al. Differentially expressed genes in nonsmall cell lung cancer: expression profiling of cancer-related genes in squamous cell lung cancer. Cancer Genet Cytogenet 149 (2004) 98-106
    • (2004) Cancer Genet Cytogenet , vol.149 , pp. 98-106
    • Kettunen, E.1    Anttila, S.2    Seppanen, J.K.3
  • 13
    • 2542521484 scopus 로고    scopus 로고
    • Kruppel-like factor 6 is frequently down-regulated and induces apoptosis in non-small cell lung cancer cells
    • Ito G., Uchiyama M., Kondo M., et al. Kruppel-like factor 6 is frequently down-regulated and induces apoptosis in non-small cell lung cancer cells. Cancer Res 64 (2004) 3838-3843
    • (2004) Cancer Res , vol.64 , pp. 3838-3843
    • Ito, G.1    Uchiyama, M.2    Kondo, M.3
  • 14
    • 0012508834 scopus 로고    scopus 로고
    • Pharmacologic unmasking of epigenetically silenced tumor suppressor genes in esophageal squamous cell carcinoma
    • Yamashita K., Upadhyay S., Osada M., et al. Pharmacologic unmasking of epigenetically silenced tumor suppressor genes in esophageal squamous cell carcinoma. Cancer Cell 2 (2002) 485-495
    • (2002) Cancer Cell , vol.2 , pp. 485-495
    • Yamashita, K.1    Upadhyay, S.2    Osada, M.3
  • 15
    • 34247123659 scopus 로고    scopus 로고
    • Methylation status of genes upregulated by demethylating agent 5-aza-2′-deoxycytidine in hepatocellular carcinoma
    • Hirasawa Y., Arai M., Imazeki F., et al. Methylation status of genes upregulated by demethylating agent 5-aza-2′-deoxycytidine in hepatocellular carcinoma. Oncology 71 (2006) 77-85
    • (2006) Oncology , vol.71 , pp. 77-85
    • Hirasawa, Y.1    Arai, M.2    Imazeki, F.3
  • 16
    • 13944252065 scopus 로고    scopus 로고
    • A germline DNA polymorphism enhances alternative splicing of the KLF6 tumor suppressor gene and is associated with increased prostate cancer risk
    • Narla G., Difeo A., Reeves H.L., et al. A germline DNA polymorphism enhances alternative splicing of the KLF6 tumor suppressor gene and is associated with increased prostate cancer risk. Cancer Res 65 (2005) 1213-1222
    • (2005) Cancer Res , vol.65 , pp. 1213-1222
    • Narla, G.1    Difeo, A.2    Reeves, H.L.3
  • 17
    • 21344473196 scopus 로고    scopus 로고
    • Targeted inhibition of the KLF6 splice variant, KLF6 SV1, suppresses prostate cancer cell growth and spread
    • Narla G., DiFeo A., Yao S., et al. Targeted inhibition of the KLF6 splice variant, KLF6 SV1, suppresses prostate cancer cell growth and spread. Cancer Res 65 (2005) 5761-5768
    • (2005) Cancer Res , vol.65 , pp. 5761-5768
    • Narla, G.1    DiFeo, A.2    Yao, S.3
  • 18
    • 18544365698 scopus 로고    scopus 로고
    • Gene expression profiles predict survival of patients with lung adenocarcinoma
    • Beer D.G., Kardia S.L.R., Huang C.C., et al. Gene expression profiles predict survival of patients with lung adenocarcinoma. Nat Med 8 (2002) 816-824
    • (2002) Nat Med , vol.8 , pp. 816-824
    • Beer, D.G.1    Kardia, S.L.R.2    Huang, C.C.3
  • 19
    • 39449090999 scopus 로고    scopus 로고
    • A functional role for KLF6-SV1 in lung adenocarcinoma prognosis and chemotherapy response
    • DiFeo A., Feld L., Rodriguez E., et al. A functional role for KLF6-SV1 in lung adenocarcinoma prognosis and chemotherapy response. Cancer Res 68 (2008) 965-970
    • (2008) Cancer Res , vol.68 , pp. 965-970
    • DiFeo, A.1    Feld, L.2    Rodriguez, E.3
  • 20
    • 70350622329 scopus 로고    scopus 로고
    • Inhibition of KLF6-SV1 increases ovarian cancer survival through the regulation of NOXA
    • in press
    • DiFeo A, Narla G, Huang F, et al. Inhibition of KLF6-SV1 increases ovarian cancer survival through the regulation of NOXA, Cancer Res, in press.
    • Cancer Res
    • DiFeo, A.1    Narla, G.2    Huang, F.3
  • 21
    • 48749088691 scopus 로고    scopus 로고
    • KLF6-SV1 is a key regulator of metastasis and survival in prostate cancer
    • Narla G., DiFeo A., Fernandez Y., et al. KLF6-SV1 is a key regulator of metastasis and survival in prostate cancer. J Clin Invest 118 (2008) 2711-2721
    • (2008) J Clin Invest , vol.118 , pp. 2711-2721
    • Narla, G.1    DiFeo, A.2    Fernandez, Y.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.