A new kind f drug target

Scientific American

Volumn 301, Issue 2, 2009, Pages 70-76

  Wenner, Melinda ^a  

^a NONE

Author keywords

[No Author keywords available]

Indexed keywords

CELL SURFACE RECEPTOR; DRUG; G PROTEIN COUPLED RECEPTOR; METABOTROPIC RECEPTOR; METABOTROPIC RECEPTOR 5;

ARTICLE; BINDING SITE; DRUG DELIVERY SYSTEM; DRUG EFFECT; ENZYME ACTIVE SITE; HUMAN; PHARMACEUTICS; SIGNAL TRANSDUCTION;

ALLOSTERIC SITE; CATALYTIC DOMAIN; DRUG DELIVERY SYSTEMS; HUMANS; PHARMACEUTICAL PREPARATIONS; RECEPTORS, CELL SURFACE; RECEPTORS, G-PROTEIN-COUPLED; RECEPTORS, METABOTROPIC GLUTAMATE; SIGNAL TRANSDUCTION; TECHNOLOGY, PHARMACEUTICAL;

EID: 68949187790     PISSN: 00368733     EISSN: None     Source Type: Journal    
DOI: 10.1038/scientificamerican0809-70     Document Type: Article

References (4)

1. New Bull's-Eyes for Drugs. Terry Kenakin in Scientific American, Vol.293, No.4, pages 50-57; October 2005.
2. Allosteric Modulation of G Protein-Coupled Receptors. L. T. May, K. Leach, P. M. Sexton and A. Christopoulos in Annual Review of Pharmacology and Toxicology, Vol.47, pages 1-51; 2007.
3. Allosteric Modulators of GPCRs: A Novel Approach for the Treatment of CNS Disorders. P. Jeffrey Conn, Arthur Christopoulos and Craig W. Lindsley in Nature Reviews Drug Discovery, Vol.8, No.1, pages 41-54; January 2009.
4. Promise of mGluR2/3 Activators in Psychiatry. P. Jeffrey Conn and Carrie K. Jones in Neuropsycho-pharmacology, Vol.34, No.1, pages 248-249; January 2009.