Neointimal-specific induction of apoptosis by losartan results in regression of vascular lesion in rat aorta

European Journal of Pharmacology

Volumn 618, Issue 1-3, 2009, Pages 45-51

  Lemay, Jacinthe ^a   Hale, Taben M ^a   deBlois, Denis ^a  

^a UNIVERSITÉ DE MONTRÉAL   (Canada)

Author keywords

Apoptosis; Blood pressure; Losartan; Vascular injury; Vascular smooth muscle

Indexed keywords

DNA; LOSARTAN; PLACEBO;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; AORTA INJURY; APOPTOSIS; ARTERY INTIMA; ARTERY INTIMA PROLIFERATION; ARTICLE; BLOOD PRESSURE MEASUREMENT; BLOOD PRESSURE REGULATION; CARDIOVASCULAR DISEASE; CONTROLLED STUDY; DNA FRAGMENTATION; DRUG MECHANISM; HYPERTENSION; MALE; NICK END LABELING; NONHUMAN; PERCUTANEOUS TRANSLUMINAL ANGIOPLASTY; PLETHYSMOGRAPHY; PRIORITY JOURNAL; RAT; SMOOTH MUSCLE FIBER; TREATMENT DURATION;

ANGIOPLASTY, BALLOON; ANIMALS; ANTIHYPERTENSIVE AGENTS; AORTA; APOPTOSIS; BCL-X PROTEIN; BLOOD PRESSURE; BODY WEIGHT; CELL COUNT; DNA FRAGMENTATION; GENE EXPRESSION REGULATION; HUMANS; LOSARTAN; MALE; PROTO-ONCOGENE PROTEINS C-AKT; RATS; RATS, INBRED SHR; RECEPTOR, ANGIOTENSIN, TYPE 2; TUNICA INTIMA;

EID: 68949184709     PISSN: 00142999     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.ejphar.2009.07.014     Document Type: Article

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