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Volumn 2, Issue 6, 2009, Pages 566-571

3,3′-Diindolylmethane induction of p75NTR-dependent cell death via the p38 mitogen-activated protein kinase pathway in prostate cancer cells

Author keywords

[No Author keywords available]

Indexed keywords

3 INDOLEMETHANOL; 3,3 DIINDOLYLMETHANE; 5 METHYLINDOLE 3 ACETIC ACID; ANTINEOPLASTIC AGENT; ETODOLAC; INDOMETACIN; KETOROLAC; MITOGEN ACTIVATED PROTEIN KINASE P38; NEUROTROPHIN RECEPTOR P75; NONSTEROID ANTIINFLAMMATORY AGENT; SMALL INTERFERING RNA; UNCLASSIFIED DRUG; 3,3' DIINDOLYLMETHANE; 3,3'-DIINDOLYLMETHANE; DRUG DERIVATIVE; ECDYSTERONE; HYBRID PROTEIN; INDOLE DERIVATIVE; NERVE GROWTH FACTOR RECEPTOR; NERVE PROTEIN; NGFR PROTEIN, HUMAN; PONASTERONE A; TUMOR PROTEIN;

EID: 68949173808     PISSN: 19406207     EISSN: None     Source Type: Journal    
DOI: 10.1158/1940-6207.CAPR-08-0202     Document Type: Article
Times cited : (25)

References (42)
  • 1
    • 0034057928 scopus 로고    scopus 로고
    • The effect of non-steroidal anti-inflammatory drugs on human colorectal cancer cells: Evidence of different mechanisms of action
    • DOI 10.1016/S0959-8049(99)00333-0, PII S0959804999003330
    • Smith ML, Hawcroft G, Hull MA. The effect of nonsteroidal anti-inflammatory drugs on human colorectal cancer cells: evidence of different mechanisms of action. Eur J Cancer 2001;36:664-674 (Pubitemid 30156854)
    • (2000) European Journal of Cancer , vol.36 , Issue.5 , pp. 664-674
    • Smith, M.-L.1    Hawcroft, G.2    Hull, M.A.3
  • 5
    • 0035942499 scopus 로고    scopus 로고
    • Indole-3-carbinol (I3C) induced cell growth inhibition, G1 cell cycle arrest and apoptosis in prostate cancer cells
    • Chinni SR, Li Y, Upadhyay S, Koppolu PK, Sarkar FH. Indole-3-carbinol (I3C) induced cell growth inhibition, G1 cell cycle arrest and apoptosis in prostate cancer cells. Oncogene 2001;20:2927-2936
    • (2001) Oncogene , vol.20 , pp. 2927-2936
    • Chinni, S.R.1    Li, Y.2    Upadhyay, S.3    Koppolu, P.K.4    Sarkar, F.H.5
  • 6
    • 0038402729 scopus 로고    scopus 로고
    • Indole-3-carbinol and 3,3′-diindolylmethane induce apoptosis in human prostate cancer cells
    • DOI 10.1016/S0278-6915(03)00004-8
    • Nachshon-Kedmi M, Yannai S, Haj A, Fares FA. Indole-3-carbinol and 3,3′diindolylmethane induce apoptosis in human prostate cancer cells. Food Chem Toxicol 2003;41:745-752 (Pubitemid 36555879)
    • (2003) Food and Chemical Toxicology , vol.41 , Issue.6 , pp. 745-752
    • Nachshon-Kedmi, M.1    Yannai, S.2    Haj, A.3    Fares, F.A.4
  • 7
  • 8
    • 33751099101 scopus 로고    scopus 로고
    • Indole-3-carbinol mediated cell cycle arrest of LNCaP human prostate cancer cells requires the induced production of activated p53 tumor suppressor protein
    • DOI 10.1016/j.bcp.2006.08.012, PII S0006295206005065
    • Hsu J, Dev A, Wing A, Brew CT, Bjeldanes LF, Firestine GL. Indole-3-carbinol mediated cell cycle arrest of LNCaP human prostate cancer cells requires the induced production of activated p53 tumor suppressor protein. Biochem Pharmacol 2006;72:1714-1723 (Pubitemid 44765004)
    • (2006) Biochemical Pharmacology , vol.72 , Issue.12 , pp. 1714-1723
    • Hsu, J.C.1    Dev, A.2    Wing, A.3    Brew, C.T.4    Bjeldanes, L.F.5    Firestone, G.L.6
  • 9
    • 0344844481 scopus 로고    scopus 로고
    • Indole-3-Carbinol Induces a G1 Cell Cycle Arrest and Inhibits Prostate-Specific Antigen Production in Human LNCaP Prostate Carcinoma Cells
    • DOI 10.1002/cncr.11844
    • Zhang J, Hsu JC, Kinseth MA, Bjeldanes LF, Firestine GL. Indole-3-carbinol induces a G1 cell cycle arrest and inhibits prostate-specific antigen production in human LNCaP prostate cancer cells. Cancer 2003;98:2511-2520 (Pubitemid 37466668)
    • (2003) Cancer , vol.98 , Issue.11 , pp. 2511-2520
    • Zhang, J.1    Hsu, J.C.2    Kinseth, M.A.3    Bjeldanes, L.F.4    Firestone, G.L.5
  • 10
    • 22144452570 scopus 로고    scopus 로고
    • Indole-3-carbinol suppresses NFκB and IκBα kinase activation, causing inhibition of expression of NFκB-regulated antiapoptotic and metastatic gene products and enhancement of apoptosis in myeloid and leukemia cells
    • Takada Y, Andreeff M, Aggarwal BB. Indole-3-carbinol suppresses NFκB and IκBα kinase activation, causing inhibition of expression of NFκB-regulated antiapoptotic and metastatic gene products and enhancement of apoptosis in myeloid and leukemia cells. Blood 2005;106:641-649
    • (2005) Blood , vol.106 , pp. 641-649
    • Takada, Y.1    Andreeff, M.2    Aggarwal, B.B.3
  • 11
    • 22344435857 scopus 로고    scopus 로고
    • Inhibition of cell proliferation and in vitro markers of angiogenesis by indole-3-carbinol, a maker indole metabolite present in cruciferous vegetables
    • Wu H-T, Lin S-H, Chen YH. Inhibition of cell proliferation and in vitro markers of angiogenesis by indole-3-carbinol, a maker indole metabolite present in cruciferous vegetables. J Agric Food Chem 2005;53:5164-5169
    • (2005) J Agric Food Chem , vol.53 , pp. 5164-5169
    • Wu, H.-T.1    Lin, S.-H.2    Chen, Y.H.3
  • 12
    • 25444449603 scopus 로고    scopus 로고
    • Molecular targets and anticancer potential of indole-3-carbinol and its derivatives
    • Aggarwal BB, Ichikawa H. Molecular targets and anticancer potential of indole-3-carbinol and its derivatives. Cell Cycle 2005;4:1201-1215
    • (2005) Cell Cycle , vol.4 , pp. 1201-1215
    • Aggarwal, B.B.1    Ichikawa, H.2
  • 13
    • 0037662282 scopus 로고    scopus 로고
    • Bax translocation to mitochondria is an important event in inducing apoptosis cell death by indole-3-carbinol (I3C) treatment of breast cancer cells
    • Review
    • Sarkar FH, Rahman W, Li Y. Bax translocation to mitochondria is an important event in inducing apoptosis cell death by indole-3-carbinol (I3C) treatment of breast cancer cells. J Nutr 2003;133:2434-9S, Review.
    • (2003) J Nutr , vol.133
    • Sarkar, F.H.1    Rahman, W.2    Li, Y.3
  • 15
    • 34047136753 scopus 로고    scopus 로고
    • Cruciferous vegetables and human cancer risk: Epidemiologic evidence and mechanistic basis
    • Higdon JV, Delage B, Williams DE, Dashwood RH. Cruciferous vegetables and human cancer risk: epidemiologic evidence and mechanistic basis. Pharmacol Res 2007;55:224-236
    • (2007) Pharmacol Res , vol.55 , pp. 224-236
    • Higdon, J.V.1    Delage, B.2    Williams, D.E.3    Dashwood, R.H.4
  • 16
    • 40949131914 scopus 로고    scopus 로고
    • Mammalian target of rapamycin repression by 3,3′-diindolylmethane inhibits invasion and angiogenesis in platelet-derived growth factor-D-overexpressing PC-3 cells
    • Kong D, Banerjee S, Huang W, et al. Mammalian target of rapamycin repression by 3,3′-diindolylmethane inhibits invasion and angiogenesis in platelet-derived growth factor-D-overexpressing PC-3 cells. Cancer Res 2008;68:1927-1934
    • (2008) Cancer Res , vol.68 , pp. 1927-1934
    • Kong, D.1    Banerjee, S.2    Huang, W.3
  • 18
    • 34248222508 scopus 로고    scopus 로고
    • NTR-dependent decreased survival of prostate tumor cells
    • NTR-dependent decreased survival of prostate tumor cells. Cancer Res 2007;67:3254-3262
    • (2007) Cancer Res , vol.67 , pp. 3254-3262
    • Quann, E.1    Khwaja, F.2    Zavitz, K.H.3
  • 19
    • 32344450355 scopus 로고    scopus 로고
    • The p75 (NTR) tumor suppressor induces cell cycle arrest facilitating caspase mediated apoptosis in prostate tumor cells
    • Khwaja F, Tabassum A, Allen J, et al. The p75 (NTR) tumor suppressor induces cell cycle arrest facilitating caspase mediated apoptosis in prostate tumor cells. Biochem Biophys Res Commun 2006;341:1184-1192
    • (2006) Biochem Biophys Res Commun , vol.341 , pp. 1184-1192
    • Khwaja, F.1    Tabassum, A.2    Allen, J.3
  • 21
    • 0036637235 scopus 로고    scopus 로고
    • Chemoprevention: An essential approach to controlling cancer
    • Sporn MB, Suh N. Chemoprevention: an essential approach to controlling cancer. Nat Rev Cancer 2002;2:537-543
    • (2002) Nat Rev Cancer , vol.2 , pp. 537-543
    • Sporn, M.B.1    Suh, N.2
  • 22
    • 35348892555 scopus 로고    scopus 로고
    • Prostate cancer chemoprevention: Current status and future prospects
    • Gupta S. Prostate cancer chemoprevention: current status and future prospects. Toxicol Appl Pharmacol 2007;224:369-376
    • (2007) Toxicol Appl Pharmacol , vol.224 , pp. 369-376
    • Gupta, S.1
  • 23
    • 35649024295 scopus 로고    scopus 로고
    • Prostate cancer prevention
    • Fleshner N, Zlotta AR. Prostate cancer prevention. Cancer 2007;110:1889-189943.
    • (2007) Cancer , vol.110 , pp. 1889-189943
    • Fleshner, N.1    Zlotta, A.R.2
  • 26
    • 34047136753 scopus 로고    scopus 로고
    • Cruciferous vegetables and human cancer risk: Epidemiological evidence and mechanistic basis
    • Higdon JV, Delage B, Williams DE, Dashwood RH. Cruciferous vegetables and human cancer risk: epidemiological evidence and mechanistic basis. Pharmacol Res 2007;55:224-236
    • (2007) Pharmacol Res , vol.55 , pp. 224-236
    • Higdon, J.V.1    Delage, B.2    Williams, D.E.3    Dashwood, R.H.4
  • 27
    • 2442672870 scopus 로고    scopus 로고
    • Physiological modeling of formulated and crystalline 3,3′- diindolylmethane pharmacokinetics following oral administration in mice
    • Anderton MJ, Manson MM, Williams ML, Mager DE. Physiological modeling of formulated and crystalline 3,3′-diindolylmethane pharmacokinetics following oral administration in mice. Drug Metab Dispos 2004;32:632-638
    • (2004) Drug Metab Dispos , vol.32 , pp. 632-638
    • Anderton, M.J.1    Manson, M.M.2    Williams, M.L.3    Mager, D.E.4
  • 28
    • 33750541268 scopus 로고    scopus 로고
    • Down-regulation of androgen receptor by 3,3′-diindolylmethane contributes to inhibition of cell proliferation and induction of apoptosis in both hormone-sensitive LNCaP and insensitive C4-2B prostate cancer cells
    • Bhuiyan MMR, Li Y, Banerjee S, et al. Down-regulation of androgen receptor by 3,3′-diindolylmethane contributes to inhibition of cell proliferation and induction of apoptosis in both hormone-sensitive LNCaP and insensitive C4-2B prostate cancer cells. Cancer Res 2006;66:10064-10072
    • (2006) Cancer Res , vol.66 , pp. 10064-10072
    • Bhuiyan, M.M.R.1    Li, Y.2    Banerjee, S.3
  • 29
    • 0035528832 scopus 로고    scopus 로고
    • NTR is a tumor suppressor in human prostate cancer
    • NTR is a tumor suppressor in human prostate cancer. Anticancer Res 2001;21:3749-3755
    • (2001) Anticancer Res , vol.21 , pp. 3749-3755
    • Krygier, S.1    Djakiew, D.2
  • 30
    • 0036497965 scopus 로고    scopus 로고
    • NTR suppresses growth and nerve growth factor-mediated metastasis of human prostate cancer cells
    • NTR suppresses growth and nerve growth factor-mediated metastasis of human prostate cancer cells. Int J Cancer 2002;98:1-7.
    • (2002) Int J Cancer , vol.98 , pp. 1-7
    • Krygier, S.1    Djakiew, D.2
  • 32
    • 0035017838 scopus 로고    scopus 로고
    • NTR loss of the expression in human prostate tumor cells
    • NTR loss of the expression in human prostate tumor cells. Mol Carcinog 2001;31:46-55.
    • (2001) Mol Carcinog , vol.31 , pp. 46-55
    • Krygier, S.1    Djakiew, D.2
  • 34
    • 33645349584 scopus 로고    scopus 로고
    • Synthetic dimer of indole-3-carbinol: Second generation diet derived ant-cancer agent in hormone sensitive prostate cancer
    • Garikapaty VP, Ashok BT, Tadi K, Mittelman A, Tiwari RK. Synthetic dimer of indole-3-carbinol: Second generation diet derived ant-cancer agent in hormone sensitive prostate cancer. Prostate 2006;66:453-462
    • (2006) Prostate , vol.66 , pp. 453-462
    • Garikapaty, V.P.1    Ashok, B.T.2    Tadi, K.3    Mittelman, A.4    Tiwari, R.K.5
  • 35
    • 0038402729 scopus 로고    scopus 로고
    • Indole-3-carbinol and 3,3′diindolylmethane induce apoptosis in human prostate cancer cells
    • Nachshon-Kedmi M, Yannai S, Haj A, Fares FA. Indole-3-carbinol and 3,3′diindolylmethane induce apoptosis in human prostate cancer cells. Food Chem Toxicol 2003;41:745-752
    • (2003) Food Chem Toxicol , vol.41 , pp. 745-752
    • Nachshon-Kedmi, M.1    Yannai, S.2    Haj, A.3    Fares, F.A.4
  • 36
    • 34248178375 scopus 로고    scopus 로고
    • Inhibition of angiogenesis and invasion by 3,3′-diindolylmethane is mediated by the nuclear factor-κB downstream target genes MMP-9 and uPA that regulate bioavailability of vascular endothelial growth factor in prostate cancer
    • Kong D, Li Y, Wang Z, Banerjee S, Sarkar FH. Inhibition of angiogenesis and invasion by 3,3′-diindolylmethane is mediated by the nuclear factor-κB downstream target genes MMP-9 and uPA that regulate bioavailability of vascular endothelial growth factor in prostate cancer. Cancer Res 2007;67:3310-3319
    • (2007) Cancer Res , vol.67 , pp. 3310-3319
    • Kong, D.1    Li, Y.2    Wang, Z.3    Banerjee, S.4    Sarkar, F.H.5
  • 37
    • 33748967964 scopus 로고    scopus 로고
    • NTR metastasis suppressor inhibits urokinase plasminogen activator, matrix metalloproteinase-2 and matrix metalloproteinase-9 in PC-3 prostate cancer cells
    • NTR metastasis suppressor inhibits urokinase plasminogen activator, matrix metalloproteinase-2 and matrix metalloproteinase-9 in PC-3 prostate cancer cells. Clin Exp Metastasis 2006;23:107-116
    • (2006) Clin Exp Metastasis , vol.23 , pp. 107-116
    • Nalbandian, A.1    Djakiew, D.2
  • 38
    • 33645294370 scopus 로고    scopus 로고
    • 3,3′-diindolylmethane (DIM) and its derivatives induce apoptosis in pancreatic cancer cells through endoplasmic reticulum stress-dependent upregulation of DR5
    • Abdelrahim M, Newman K, Vanderlagg K, Samudio I, Safe S. 3,3′-diindolylmethane (DIM) and its derivatives induce apoptosis in pancreatic cancer cells through endoplasmic reticulum stress-dependent upregulation of DR5. Carcinogenesis 2006;27:717-728
    • (2006) Carcinogenesis , vol.27 , pp. 717-728
    • Abdelrahim, M.1    Newman, K.2    Vanderlagg, K.3    Samudio, I.4    Safe, S.5
  • 39
    • 16444364134 scopus 로고    scopus 로고
    • DIM stimulates IFNγ gene expression in human breast cancer cells via the specific activation of JNK and p38 pathways
    • Xue L, Firestone GL, Bjeldanes LF. DIM stimulates IFNγ gene expression in human breast cancer cells via the specific activation of JNK and p38 pathways. Oncogene 2005;24:2343-2353
    • (2005) Oncogene , vol.24 , pp. 2343-2353
    • Xue, L.1    Firestone, G.L.2    Bjeldanes, L.F.3
  • 40
    • 19644367000 scopus 로고    scopus 로고
    • Activation and signaling of the p38 MAP kinase pathway
    • Zarubin T, Han J. Activation and signaling of the p38 MAP kinase pathway. Cell Res 2005;15:11-18
    • (2005) Cell Res , vol.15 , pp. 11-18
    • Zarubin, T.1    Han, J.2
  • 42
    • 13544257285 scopus 로고    scopus 로고
    • NTR mediates a bifurcated signal transduction cascade through the NFκB and JNK pathways to inhibit cell survival
    • NTR mediates a bifurcated signal transduction cascade through the NFκB and JNK pathways to inhibit cell survival. Exp Cell Res 2005;304:69-80.
    • (2005) Exp Cell Res , vol.304 , pp. 69-80
    • Allen, J.1    Khwaja, F.2    Byers, S.3    Djakiew, D.4


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.