Toll-like receptor 4 mediates lipopolysaccharide-induced collagen secretion by phosphoinositide3-kinase-akt pathway in fibroblasts during acute lung injury

Journal of Receptors and Signal Transduction

Volumn 29, Issue 2, 2009, Pages 119-125

  He, Zhengyu ^a   Zhu, Yesen ^a   Jiang, Hong ^a  

^a SHANGHAI JIAO TONG UNIVERSITY   (China)

Author keywords

Acute lung injury; Fibroblasts; Lipopolysaccharides; PI3K Akt pathway; Toll like receptor4

Indexed keywords

2 MORPHOLINO 8 PHENYLCHROMONE; ALPHA SMOOTH MUSCLE ACTIN; BETA1 INTEGRIN; CARBOXY TERMINAL TELOPEPTIDE; COLLAGEN; LIPOPOLYSACCHARIDE; PHOSPHATIDYLINOSITOL 3 KINASE; PROCOLLAGEN C PROTEINASE; PROTEIN KINASE B; TOLL LIKE RECEPTOR 4; 2-(4-MORPHOLINYL)-8-PHENYL-4H-1-BENZOPYRAN-4-ONE; CHROMONE DERIVATIVE; COLLAGEN TYPE 1; ENZYME INHIBITOR; MORPHOLINE DERIVATIVE;

ACUTE LUNG INJURY; ANIMAL CELL; ARTICLE; CELL STIMULATION; CONTROLLED STUDY; ENZYME ACTIVATION; FIBROBLAST CULTURE; FIBROSING ALVEOLITIS; GENE OVEREXPRESSION; GENETIC TRANSFECTION; IN VITRO STUDY; LENTIVIRINAE; LUNG ALVEOLUS MACROPHAGE; LUNG FIBROBLAST; MOLECULAR MECHANICS; MOUSE; NONHUMAN; PATHOGENESIS; PROTEIN EXPRESSION; PROTEIN SECRETION; REAL TIME POLYMERASE CHAIN REACTION; SIGNAL TRANSDUCTION; SUPERNATANT; TARGET CELL; UPREGULATION; WESTERN BLOTTING; ANIMAL; C57BL MOUSE; CELL CULTURE; DRUG EFFECT; DRUG POTENTIATION; FIBROBLAST; IMMUNOLOGY; LUNG; METABOLISM; MICROBIOLOGY; PHYSIOLOGY;

BACILLI (CLASS); BACILLUS (BACTERIUM); LENTIVIRUS; NEGIBACTERIA;

1-PHOSPHATIDYLINOSITOL 3-KINASE; ACUTE LUNG INJURY; ANIMALS; ANTIGENS, CD29; CELLS, CULTURED; CHROMONES; COLLAGEN TYPE I; ENZYME INHIBITORS; FIBROBLASTS; LIPOPOLYSACCHARIDES; LUNG; MICE; MICE, INBRED C57BL; MORPHOLINES; PROTO-ONCOGENE PROTEINS C-AKT; SIGNAL TRANSDUCTION; TOLL-LIKE RECEPTOR 4; UP-REGULATION;

EID: 68949172222     PISSN: 10799893     EISSN: 15324281     Source Type: Journal    
DOI: 10.1080/10799890902845690     Document Type: Article

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