Domino alkylation-cyclization reaction of propargyl bromides with thioureas/thiopyrimidinones: A new facile synthesis of 2-aminothiazoles and 5H-thiazolo[3,2-α]pyrimidin-5-ones

Synlett

Volumn , Issue 13, 2009, Pages 2093-2096

  Castagnolo, Daniele ^a   Pagano, Mafalda ^a   Bernardini, Martina ^a   Botta, Maurizio ^a,b  

^a UNIVERSITY OF SIENA   (Italy)

^b Temple University   (United States)

Author keywords

2 aminothiazole; Antiviral agents; Domino reaction; Microwave synthesis; Thiazolopyrimidinone

Indexed keywords

2 AMINOTHIAZOLE DERIVATIVE; ANTIVIRUS AGENT; BROMINE DERIVATIVE; PYRIMIDINONE DERIVATIVE; THIOUREA DERIVATIVE;

ALKYLATION; ANTIVIRAL ACTIVITY; ARTICLE; CYCLIZATION; DRUG STRUCTURE; DRUG SYNTHESIS; HUMAN IMMUNODEFICIENCY VIRUS; NUCLEAR OVERHAUSER EFFECT; REACTION TIME; SONOGASHIRA REACTION;

EID: 68949163954     PISSN: 09365214     EISSN: 14372096     Source Type: Journal    
DOI: 10.1055/s-0029-1217700     Document Type: Article

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