Functions, structures and Triton X-100 effect for the catalytic subunits of heterodimeric phospholipases A2 from Vipera nikolskii venom

Toxicon

Volumn 54, Issue 6, 2009, Pages 709-716

  Gao, Wei ^a,b   Starkov, Vladislav G ^c   He, Zi xuan ^a   Wang, Qi hai ^a   Tsetlin, Victor I ^c   Utkin, Yuri N ^c   Lin, Zheng jiong ^a   Bi, Ru chang ^a  

^a INSTITUTE OF BIOPHYSICS   (China)

^b BEIJING FORESTRY UNIVERSITY   (China)

^c SHEMYAKIN OVCHINNIKOV INSTITUTE OF BIOORGANIC CHEMISTRY   (Russian Federation)

Author keywords

Neurotoxicity; Phospholipase A2; Triton X 100; Viper venom; X ray structure

Indexed keywords

CALCIUM ION; HETERODIMER; PHOSPHOLIPASE A2 GROUP II; PROTEIN HDP 1P; PROTEIN HDP 2P; SNAKE VENOM; TRITON X 100; UNCLASSIFIED DRUG;

ANIMAL CELL; ARTICLE; CALCIUM BINDING; CATALYSIS; CONFORMATIONAL TRANSITION; CONTROLLED STUDY; CRYSTAL STRUCTURE; ENZYME ACTIVE SITE; ENZYME ACTIVITY; ENZYME STRUCTURE; ENZYME SUBUNIT; EXOCYTOSIS; HYDROPHOBICITY; NERVE BLOCK; NEUROTOXICITY; NONHUMAN; NUCLEOTIDE SEQUENCE; PANCREAS ISLET BETA CELL; PRESYNAPTIC INHIBITION; PRIORITY JOURNAL; PROTEIN BINDING; RAT; SNAKE;

AMINO ACID SEQUENCE; ANIMALS; CATALYTIC DOMAIN; CELL LINE; CRYSTALLIZATION; DIMERIZATION; MODELS, MOLECULAR; MOLECULAR SEQUENCE DATA; OCTOXYNOL; PHOSPHOLIPASES A2; SEQUENCE HOMOLOGY, AMINO ACID; STRUCTURE-ACTIVITY RELATIONSHIP; VIPER VENOMS;

VIPERA NIKOLSKII; VIPERINAE;

EID: 68949157269     PISSN: 00410101     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.toxicon.2009.05.024     Document Type: Article

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