Mitochondrial uncoupling protein 2 inhibits mast cell activation and reduces histamine content

Journal of Immunology

Volumn 183, Issue 10, 2009, Pages 6313-6319

  Tagen, Michael ^a,d   Elorza, Alvaro ^b   Kempuraj, Duraisamy ^a   Boucher, William ^a   Kepley, Christopher L ^c   Shirihai, Orian S ^b   Theoharides, Theoharis C ^a  

^a TUFTS UNIVERSITY SCHOOL OF MEDICINE   (United States)

^b BOSTON UNIVERSITY SCHOOL OF MEDICINE   (United States)

^c LUNA INNOVATIONS INC   (United States)

^d ST JUDE CHILDREN S RESEARCH HOSPITAL   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

CYTOKINE; HISTAMINE; HISTIDINE DECARBOXYLASE; HUMAN SERUM ALBUMIN; INTERLEUKIN 6; MANGANESE TETRAKIS(4 BENZOIC ACID PORPHYRIN); MITOGEN ACTIVATED PROTEIN KINASE; PORPHYRIN DERIVATIVE; PROSTAGLANDIN; PROSTAGLANDIN D2; REACTIVE OXYGEN METABOLITE; SUBSTANCE P; SUPEROXIDE DISMUTASE; UNCLASSIFIED DRUG; UNCOUPLING PROTEIN 2;

ALLERGY; ANIMAL CELL; ANIMAL EXPERIMENT; ARTICLE; BLOOD VESSEL PERMEABILITY; CELL ACTIVATION; CONTROLLED STUDY; CYTOKINE RELEASE; ENZYME PHOSPHORYLATION; FEMALE; HISTAMINE RELEASE; HUMAN; HUMAN CELL; INFLAMMATION; INSULIN RELEASE; MALE; MAST CELL; MOUSE; NONHUMAN; PANCREAS ISLET BETA CELL; PRIORITY JOURNAL; PROSTAGLANDIN RELEASE; PROSTAGLANDIN SYNTHESIS; PROTEIN EXPRESSION; REGULATORY MECHANISM; SENSITIZATION;

ANIMALS; CAPILLARY PERMEABILITY; CELL DEGRANULATION; CELL LINE, TUMOR; DINITROPHENOLS; EXTRACELLULAR SIGNAL-REGULATED MAP KINASES; HISTAMINE; HISTAMINE RELEASE; HUMANS; INTERLEUKIN-6; ION CHANNELS; IONOMYCIN; IONOPHORES; MAST CELLS; MICE; MICE, KNOCKOUT; MITOCHONDRIA; MITOCHONDRIAL PROTEINS; PHOSPHORYLATION; PORPHYRINS; PROSTAGLANDIN D2; SERUM ALBUMIN;

EID: 68949130040     PISSN: 00221767     EISSN: 15506606     Source Type: Journal    
DOI: 10.4049/jimmunol.0803422     Document Type: Article

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