Cornuside attenuates apoptosis and ameliorates mitochondrial energy metabolism in rat cortical neurons

Pharmacology

Volumn 84, Issue 3, 2009, Pages 162-170

  Jiang, Wang Lin ^a   Chen, Xi Guang ^a   Zhu, Hai Bo ^b   Hou, Jian ^b   Tian, Jing Wei ^b  

^a OCEAN UNIVERSITY OF CHINA   (China)

^b YANTAI UNIVERSITY   (China)

Author keywords

Apoptosis; Cerebral ischemia; Cornuside; Cortical neuron; Mitochondrial energy metabolism

Indexed keywords

ADENOSINE TRIPHOSPHATE; CALCIUM; CASPASE 3; CORNUSIDE; LACTATE DEHYDROGENASE; MALONALDEHYDE; SECOIRIDOID; UNCLASSIFIED DRUG;

ANIMAL CELL; APOPTOSIS; ARTICLE; BRAIN ISCHEMIA; BRAIN NERVE CELL; CELL CULTURE; CELL STRUCTURE; CELL SURVIVAL; CONTROLLED STUDY; DRUG ACTIVITY; ENERGY METABOLISM; ENZYME ACTIVITY; HIPPOCAMPUS; MITOCHONDRIAL ENERGY TRANSFER; NONHUMAN; PRIORITY JOURNAL;

ANIMALS; ANTIOXIDANTS; APOPTOSIS; BRAIN ISCHEMIA; CALCIUM; CASPASE 3; CELL SURVIVAL; CEREBRAL CORTEX; CORNUS; DOSE-RESPONSE RELATIONSHIP, DRUG; ENERGY METABOLISM; FRUIT; GLUCOSIDES; L-LACTATE DEHYDROGENASE; MITOCHONDRIA; NEURONS; PYRANS; RATS; RATS, SPRAGUE-DAWLEY;

EID: 68949117692     PISSN: 00317012     EISSN: None     Source Type: Journal    
DOI: 10.1159/000235621     Document Type: Article

References (25)

1. Fujimura M, Tominaga T, Chan PH: Neuroprotective effect of an antioxidant in ischemic brain injury: involvement of neuronal apoptosis. Neurocrit Care 2005; 2: 59-66.
2. Banasiak KJ, Xia Y, Haddad GG: Mechanisms underlying hypoxia-induced neuronal apoptosis. Prog Neurobiol 2000; 62: 215-249.
3. Lee JM, Zipfel GJ, Choi DW: The changing landscape of ischaemic brain injury mechanisms. Nature 1999; 399(6738 suppl):A7-A14.
4. Thornberry NA, Lazebnik Y: Caspases: enemies within. Science 1998; 281: 1312-1316.
5. McGinnis KM, Wang KK, Gnegy ME: Alterations of extracellular calcium elicit selective modes of cell death and protease activation in SH-SY5Y human neuroblastoma cells. J Neurochem 1999; 72: 1853-1863.
6. Kang DG, Moon MK, Lee AS, Kwon TO, Kim JS, Lee HS: Cornuside suppresses cytokine- induced proinflammatory and adhesion molecules in the human umbilical vein endothelial cells. Biol Pharm Bull 2007; 30
7. Xu HQ, Hao HP: Effects of iridoid total glycoside from Cornus officinalis on prevention of glomerular overexpression of transforming growth factor beta 1 and matrixes in an experimental diabetes model. Biol Pharm Bull 2004; 27: 1014-1018.
8. Chang JS, Chiang LC, Hsu FF, Lin CC: Chemoprevention against hepatocellular carcinoma of Cornus officinalis in vitro. Am J Chin Med 2004; 32: 717-725.
9. Jiang WL, Chen XG, Zhu HB, Tian JW: Effect of cornuside on experimental sepsis. Planta Med 2009, E-pub ahead of print.
10. Wu JB, Song NN, Wei XB, Guan HS, Zhang XM: Protective effects of paeonol on cultured rat hippocampal neurons against oxygen- glucose deprivation-induced injury. J Neurol Sci 2008; 264: 50-55.
11. Liu CS, Chen NH, Zhang JT: Protection of PC12 cells from hydrogen peroxide-induced cytotoxicity by salvianolic acid B, a new compound isolated from Radix Salviae miltiorrhizae. Phytomedicine 2007; 14: 492-497.
12. 2+ influx into respiratory neurons during hypoxia. Neuropharmacology 2005; 48: 1056-1065.
13. Li N, Ragheb K, Lawler G, Sturgis J, Rajwa B, Melendez JA, et al: Mitochondrial complex I inhibitor rotenone induces apoptosis through enhancing mitochondrial reactive oxygen species production. J Biol Chem 2003; 278: 8516-8525.
14. Lowry OH, Berger SJ, Carter JG, Chi MM, Manchester JK, Knor J, et al: Diversity of metabolic patterns in human brain tumors: enzymes of energy metabolism and related metabolites and cofactors. J Neurochem 1983; 41: 994-1010.
15. Kintner DB, Fitzpatrick JH Jr, Gilboe DD: Hyperglycemic damage to mitochondrial membranes during cerebral ischemia: amelioration by platelet-activating factor antagonist BN 50739. J Neurochem 1997; 69: 1219-1227.
16. Tian J, Fu F, Geng M, Jiang Y, Yang J, Jiang W, et al: Neuroprotective effect of 20(S)-ginsenoside Rg 3 on cerebral ischemia in rats. Neurosci Lett 2005; 374: 92-97. (Pubitemid 40092203)
17. Kaur P, Radotra B, Minz RW, Gill KD: Impaired mitochondrial energy metabolism and neuronal apoptotic cell death after chronic dichlorvos (OP) exposure in rat brain. Neurotoxicology 2007; 28: 1208-1219.
18. Mastrocola R, Restivo F, Vercellinatto I, Danni O, Brignardello E, Aragno M, et al: Oxidative and nitrosative stress in brain mitochondria of diabetic rats. J Endocrinol 2005; 187: 37-44.
19. Zaidan E, Sims NR: The calcium content of mitochondria from brain subregions following short-term forebrain ischemia and recirculation in the rat. J Neurochem 1994; 63: 1812-1819.
20. Fukushima T, Koide M, Ago Y, Baba A, Matsuda T: T-817MA, a novel neurotrophic agent, improves sodium nitroprusside-induced mitochondrial dysfunction in cortical neurons. Neurochem Int 2006; 48: 124-130.
21. Jaskot RH, Charlet EG, Grose EC, Grady MA, Roycroft JH: An automated analysis of glutathione peroxidase, S-transferase, and reductase activity in animal tissue. J Anal Toxicol 1983; 7: 86-88.
22. Ohkawa H, Ohishi N, Yagi K: Assay for lipid peroxides in animal tissues by thiobarbituric acid reaction. Anal Biochem 1979; 95: 351-358.
23. Tian J, Li G, Liu Z, Fu F: Hydroxysafflor yellow A inhibits rat brain mitochondrial permeability transition pores by a free radical scavenging action. Pharmacology 2008; 82: 121-126.
24. Chen YH, Du GH, Zhang JT: Salvianolic acid B protects brain against injuries caused by ischemia-reperfusion in rats. Acta Pharmacol Sin 2000; 21: 463-466.
25. Almeida A, Allen KL, Bates TE, Clark JB: Effect of reperfusion following cerebral ischaemia on the activity of the mitochondrial respiratory chain in the gerbil brain. J Neurochem 1995; 65: 1698-1703.