Myocardial infarction and arterial thrombosis in identical newborn twins with homozygosity for the PAI-1 4 G/5 G polymorphism

International Journal of Cardiology

Volumn 137, Issue 1, 2009, Pages

  De Lucia, Vittoria ^a   Andreassi, Maria Grazia ^b   Sabatini, Laura ^c   Ait Ali, Lamia ^a   Spadoni, Isabella ^a   Giusti, Sandra ^a  

^a G Pasquinucci Hospital   (Italy)

^b INSTITUTE OF CLINICAL PHYSIOLOGY   (Italy)

^c AOUS   (Italy)

Author keywords

Myocardial infarction; Newborn twins; PAI 1 4G 5G Poymorphism; Thrombosis

Indexed keywords

CARVEDILOL; CREATINE KINASE; CREATINE KINASE MB; DIURETIC AGENT; HEPARIN; INOTROPIC AGENT; LOW MOLECULAR WEIGHT HEPARIN; NITRATE; PLASMINOGEN ACTIVATOR INHIBITOR 1; SALICYLIC ACID; TROPONIN I; UROKINASE;

ANGIOCARDIOGRAPHY; APGAR SCORE; ARTERY THROMBOSIS; ARTICLE; BIRTH; BIRTH WEIGHT; CASE REPORT; CONTINUOUS INFUSION; DNA POLYMORPHISM; ECHOCARDIOGRAPHY; ELECTROCARDIOGRAPHY; GENETIC PREDISPOSITION; GESTATIONAL AGE; HEART INFARCTION; HEART LEFT VENTRICLE EJECTION FRACTION; HOMOZYGOSITY; HUMAN; MALE; MONOZYGOTIC TWINS; NEWBORN; NUCLEAR MAGNETIC RESONANCE IMAGING; OUTCOME ASSESSMENT; PRIORITY JOURNAL; RESUSCITATION; SINUS TACHYCARDIA;

ADULT; DISEASES IN TWINS; FEMALE; FOLLOW-UP STUDIES; HOMOZYGOTE; HUMANS; INFANT, NEWBORN; MALE; MYOCARDIAL INFARCTION; PLASMINOGEN ACTIVATOR INHIBITOR 1; POLYMORPHISM, GENETIC; THROMBOSIS; TWINS, MONOZYGOTIC;

EID: 68949116188     PISSN: 01675273     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.ijcard.2008.05.030     Document Type: Article

References (16)

1. Takeuchi M., Suzuki T., Nakayama M., Kenmochi M., and Kitajima H. Neonatal myocardial infarction due to thrombotic occlusion. J Matern Fetal Neonatal Med 19 (2006) 121-123
2. Muraskas J., Besinger R., Bell T., DeLeon S., and Husain A. Perinatal myocardial infarction in a newborn with a structurally normal heart. Am J Perinatol 14 (1997) 93-97
3. Lucas Jr. V.W., Burchfield D.J., and Donnelly Jr. W.H. Multiple coronary thromboemboli and myocardial infarction in a newborn infant. J Perinatol 14 (1994) 145-149
4. Bernstein D., Finkbeiner W.E., Soifer S., and Teitel D. Perinatal myocardial infarction: a case report and review of the literature. Pediatr Cardiol 6 (1986) 313-317
5. Barberi I., Calabro M.P., Cordaro S., et al. Myocardial ischaemia in neonates with perinatal asphyxia. Electrocardiographic, echocardiographic and enzymatic correlations. Eur J Pediatr 158 (1999) 742-747
6. Szymankiewicz M., Matuszczak-Wleklak M., Vidyasagar D., and Gadzinowski J. Retrospective diagnosis of hypoxic myocardial injury in premature newborns. J Perinat Med 34 (2006) 220-225
7. Saker D.M., Walsh-Sukys M., Spector M., and Zahka K.G. Cardiac recovery and survival after neonatal myocardial infarction. Pediatr Cardiol 18 (1997) 139-142
8. Hruda J., van de Wal H.J., Brouwers H.A., and Harinck E. Survival of a neonate after myocardial infarction complicated by late mitral regurgitation. Pediatr Cardiol 16 (1995) 131-132
9. Monagle P. Thrombosis in pediatric cardiac patients. Semin Thromb Hemost 29 (2003) 547-555
10. Dawson S.J., Wiman B., Hamsten A., Green F., Humphries S., and Henney A.M. The two allele sequences of a common polymorphism in the promoter of the plasminogen activator inhibitor-1 (PAI-1) gene respond differently to interleukin-1 in HepG2 cells. J Biol Chem 268 (1993) 10739-10745
11. Eriksson P., Kallin B., van't Hooft F.M., Båvenholm P., and Hamsten A. Allele specific increase in basal transcription of the plasminogen activator inhibitor-1 gene is associated with myocardial infarction. Proc Natl Acad Sci U S A 92 (1995) 1851-1855
12. Humphries S.E., Panahloo A., Montgomery H.E., Green F., and Yudkin J. Gene-environment interaction in the determination of levels of haemostatic variables involved in thrombosis and fibrinolysis. Thromb Haemost 78 (1997) 457-461
13. Mlynarska A., Waszyrowski T., and Kasprzak J.D. Increase in plasma plasminogen activators inhibitor type 1 concentration after fibrinolytic treatment in patients with acute myocardial infarction is associated with 4G/5G polymorphism of PAI-1 gene. J Thromb Haemost 4 (2006) 1361-1366
14. Nowak-Göttl U., Kotthoff S., Hagemeyer E., et al. Interaction of fibrinolysis and prothrombotic risk factors in neonates, infants and children with and without thromboembolism and underlying cardiac disease. A prospective study. Thromb. Res. 103 (2001) 93-101
15. Heineking B., Riebel T., Scheer I., Kulozik A., Hoehn T., and Buhrer C. Intraventricular hemorrhage in a full-term neonate associated with sinus venous thrombosis and homozygosity for the plasminogen activator inhibitor-1 4G/4G polymorphism. Pediatr Int. 45 (2003) 93-96
16. Baumeister F.A., Auberger K., and Schneider K. Thrombosis of the deep cerebral veins with excessive bilateral infarction in a premature infant with the thrombogenic 4G/4G genotype of the plasminogen activator inhibitor-1. Eur J Pediatr 159 (2000) 239-242