Thrombosis of the deep cerebral veins with excessive bilateral infarction in a premature infant with the thrombogenic 4G/4G genotype of the plasminogen activator inhibitor-1

European Journal of Pediatrics

Volumn 159, Issue 4, 2000, Pages 239-242

  Baumeister, Friedrich A M ^a   Auberger, Karin ^b   Schneider, Karl ^b  

^a TECHNICAL UNIVERSITY OF MUNICH   (Germany)

^b K/K im D v H K der U M   (Germany)

Author keywords

Deep cerebral veins; Newborn; Plasminogen activator inhibitor 1; Preterm; Thrombosis

Indexed keywords

D DIMER; PLASMINOGEN ACTIVATOR INHIBITOR 1;

ARTICLE; BRAIN INFARCTION; BRAIN VEIN; CASE REPORT; CHOROID PLEXUS; COMPUTER ASSISTED TOMOGRAPHY; DEEP VEIN THROMBOSIS; ECHOGRAPHY; GESTATIONAL AGE; HUMAN; INFANT; MALE; PREMATURITY; PRIORITY JOURNAL; RISK FACTOR; THALAMUS; THROMBOGENESIS; TONIC SEIZURE; WHITE MATTER;

EID: 0034072678     PISSN: 03406199     EISSN: None     Source Type: Journal    
DOI: 10.1007/s004310050062     Document Type: Article

References (23)

1. 1. Barron TF, Gusnard DA, Zimmerman RA, Clancy RR (1992) Cerebral venous thrombosis in neonates and children. Pediatr Neurol 8:112-116
2. 2. Crawford SC, Digre KB, Palmer CA, Bell DA, Osborn AG (1995) Thrombosis of the deep venous drainage of the brain in adults: Analysis of seven cases with review of the literature. Arch Neurol 52:1101-1108
3. 3. Ehlers H, Courville CB (1936) Thrombosis of internal cerebral veins in infancy and childhood. J Pediatr 8:600-623
4. 4. Erickson LA, Fici GJ, Lund JE, Boyle TP, Polites HG, Marotti KR (1990) Development of venous occlusions in mice transgenic for the plasminogen activator inhibitor-1 gene. Nature 346:74-76
5. 5. Eriksson ER, Kallin B, van T Hooft FM, Bavenholm P, Hamsten A (1995) Allele-specific increase in basal transcription of the plasminogen-activator inhibitor 1 gene is associated with myocardial infarction. Proc Natl Acad Sci USA 92:1851-1855
6. 6. Estellés A, Gilabert J, Aznar J, Loskutoff DJ, Schleef RR (1989) Changes in the plasma levels of type 1 and type 2 plasminogen activator inhibitors in normal pregnancy and in patients with severe preeclampsia. Blood 4:1332-1338
7. 7. Estellés A, Gilabert J, Espana F, Aznar J, Galbis M (1991) Fibrinolytic parameters in normotensive pregnancy with intrauterine fetal growth retardation and in severe preeclampsia. Am J Obstet Gynecol 165:138-142
8. 8. Falk G, Almqvist A, Nordenhem A, Svensson H, Wiman B (1995) Allele specific PCR for detection of a sequence polymorphism in the promoter region of the plasminogen activator inhibitor-1 (PAI-1) gene. Fibrinolysis 9:170-174
9. 9. Glueck CJ, Glueck HI, Welch M, Freiberg R, Tracy T, Hamer T, Stroop D (1994) Familial idiopathic osteonecrosis mediated by familial hypofibrinolysis with high levels of plasminogen activator inhibitor. Thromb Haemost 71:195-198
10. 10. Göpel W, Kim D, Gortner L (1999) Prothrombotic mutations as a risk factor for preterm birth. Lancet 353:1411-1412
11. 11. Govaert P, Achten E, Vanhaesebrouck P, De Praeter C, Van Damme J (1992) Deep cerebral venous thrombosis in thalamo-ventricular hemorrhage of the term newborn. Pediatr Radiol 22:123-127
12. 12. Govaert P, De Vries LS, Beek FJA, van Bel F (1997) Bleeding into basal ganglia and ventricle (deep venous infarction). In: Bax MCO, Davies PA (eds) An atlas of neonatal brain sonography. Mac Keith Press, London, pp 207-210
13. 13. Grubic N, Stegnar M, Peternel P, Kaider A, Binder BR (1996) A novel G/A and the 4G/5G polymorphism within the promoter of the plasminogen activator inhibitor-1 gene in patients with deep vein thrombosis. Thromb Haemost 84:431-443
14. 14. Humphries SE, Panahloo A, Montgomery HE, Green F, Yudkin J (1997) Gene-environment interaction in the determination of levels of haemostatic variables involved in thrombosis and fibrinolysis. Thromb Haemost 78:457-461
15. 15. Junker R, Nabavi DG, Wolff E, Lüdemann P, Nowak-Göttl U, Käse M, Bäumer R, Ringelstein EB, Assmann G (1998) Plasminogen activator inhibitor-1 4G/4G genotype is associated with cerebral sinus thrombosis in factor V leiden carriers. Thromb Haemost 80:706-707
16. 16. Ossei-Gerning N, Mansfield MW, Stickland MH, Wilson IJ, Grant PJ (1997) Plasminogen activator inhibitor-1 promoter 4G/5G genotype and plasma levels in relation to a history of myocardial infarction in patients characterized by coronary angiography. Arterioscler Thromb Vasc Biol 17:33-37
17. 17. Prins MH, Hirsh J (1991) A critical review of the evidence supporting a relationship between impaired fibrinolytic activity and venous thromboembolism. Arch Intern Med 151:1721-1731
18. 18. Riela AR, Roach ES (1993) Etiology of stroke in children. J Child Neurol 8:201-220
19. 19. Rivkin MJ, Anderson ML, Kaye EM (1992) Neonatal idiopathic cerebral venous thrombosis: an unrecognized cause of transient seizures or lethargy. Ann Neurol 32:51-56
20. 20. Shevell MI, Silver K, O'Gorman MO, Gordon VW, Montes JL (1989) Neonatal durai sinus thrombosis. Pediatr Neurol 5:161-165
21. 21. Wiman B (1995) Plasminogen activator inhibitor 1 (PAI-1) in plasma: its role in thrombotic disease. Thromb Haemost 74:71-76
22. 22. Xu Y, Hagege J, Mougenot B, Sraer J-D, Ronne E, Rondeau E (1996) Different expression of the plasminogen activation system in renal thrombotic microangiopathy and the normal human kidney. Kidney Int 50:2011-2019
23. 23. Zöller B, Garcia De Frutos P, Dahlbäck B (1998) A common 4G allele in the promoter of the plasminogen activator inhibitor-1 (PAI-1) gene as a risk factor for pulmonary embolism and arterial thrombosis in hereditary protein S deficiency. Thromb Haemost 78:802-807