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Volumn 22, Issue 4, 2009, Pages 483-490

Update on neuromuscular pharmacology

Author keywords

Antagonism; AV002; Cysteine; Gantacurium; Neuromuscular blockade; Neuromuscular blockers; Sugammadex

Indexed keywords

AV 002; AV 430; CHOLINESTERASE INHIBITOR; CYSTEINE; EXCITOTOXIN; FUMARIC ACID; GAMMA CYCLODEXTRIN; GANTACURIUM; GLUTATHIONE; NEOSTIGMINE; NEUROMUSCULAR BLOCKING AGENT; ROCURONIUM; SUGAMMADEX; SULFATE; SUXAMETHONIUM; TAURINE; UNCLASSIFIED DRUG; VECURONIUM;

EID: 68949113808     PISSN: 09527907     EISSN: None     Source Type: Journal    
DOI: 10.1097/ACO.0b013e32832b8cff     Document Type: Review
Times cited : (26)

References (73)
  • 1
    • 0000323076 scopus 로고
    • About the connection of local anaesthesia with general anaesthesia; About high extradural anaesthesia and epidural injection of anaesthesizing solutions for 'stomach crisis'
    • Läwen A. About the connection of local anaesthesia with general anaesthesia; about high extradural anaesthesia and epidural injection of anaesthesizing solutions for 'stomach crisis'. Beitr Klin Chir 1912; 80:168-180.
    • (1912) Beitr Klin Chir , vol.80 , pp. 168-180
    • Läwen, A.1
  • 2
    • 0000972742 scopus 로고
    • The use of curare in general anesthesia
    • Griffith H, Johnson GE. The use of curare in general anesthesia. Anesthesio-logy 1942; 3:418-420.
    • (1942) Anesthesio-Logy , vol.3 , pp. 418-420
    • Griffith, H.1    Johnson, G.E.2
  • 3
    • 68949094803 scopus 로고
    • Succinylcholine iodide: Studies on its pharmacological properties and clinical use
    • Thesleff S. Succinylcholine iodide: studies on its pharmacological properties and clinical use. Acta Physiol Scand 1952; 27:1-36.
    • (1952) Acta Physiol Scand , vol.27 , pp. 1-36
    • Thesleff, S.1
  • 4
    • 0001639633 scopus 로고
    • Succinylcholine, a new approach to muscular relaxation in anaesthesiology
    • Foldes FF, McNall PG, Borrego-Hinojosa JM. Succinylcholine, a new approach to muscular relaxation in anaesthesiology. N Engl J Med 1952; 247:596-600.
    • (1952) N Engl J Med , vol.247 , pp. 596-600
    • Foldes, F.F.1    McNall, P.G.2    Borrego-Hinojosa, J.M.3
  • 5
    • 0014141132 scopus 로고
    • The neuromuscular blocking properties of a new steroid compound, pancuronium bromide, A pilot study in man.
    • Baird WL, Reid AM. The neuromuscular blocking properties of a new steroid compound, pancuronium bromide, A pilot study in man. Br J Anaesth 1967; 3910:775-780.
    • (1967) Br J Anaesth , vol.3910 , pp. 775-780
    • Baird, W.L.1    Reid, A.M.2
  • 6
    • 0018829482 scopus 로고
    • The emergence of ORG NC 45, 1 - [2 beta,3 alpha,5 alpha,16 beta,17 beta)-3, 17-bis(acetyloxy)-2-(1-piperidinyl)-andro-stan-16-yl]-1- methylpiperidinium bromide, from the pancuronium series.
    • Savage DS, Sleigh T, Carlyle I. The emergence of ORG NC 45, 1 - [2 beta,3 alpha,5 alpha,16 beta,17 beta)-3, 17-bis(acetyloxy)-2-(1-piperidinyl)-andro- stan-16-yl]-1-methylpiperidinium bromide, from the pancuronium series. Br J Anaesth 1980; 52 (Suppl 1):3S-9S.
    • (1980) Br J Anaesth , vol.52 , Issue.SUPPL 1
    • Savage, D.S.1    Sleigh, T.2    Carlyle, I.3
  • 7
    • 0019766795 scopus 로고
    • Biodegradable neuromuscular blocking agents
    • Part 4: Atracurium besylate and related polyalkylylene di-esters
    • Stenlake JB, Waigh RD, Dewar GH, et al. Biodegradable neuromuscular blocking agents. Part 4: Atracurium besylate and related polyalkylylene di-esters. Eur J Med Chem 1981; 16:515.
    • (1981) Eur J Med Chem , vol.16 , pp. 515
    • Stenlake, J.B.1    Waigh, R.D.2    Dewar, G.H.3
  • 8
    • 0020529488 scopus 로고
    • Atracurium: Conception and inception
    • Stenlake JB, Waigh RD, Urwin J, et al. Atracurium: conception and inception. Br J Anaesth 1983; 55 (Suppl 1):3S-10S.
    • (1983) Br J Anaesth , vol.55 , Issue.SUPPL 1
    • Stenlake, J.B.1    Waigh, R.D.2    Urwin, J.3
  • 9
    • 0023936295 scopus 로고
    • The clinical neuromuscular pharmacology of mivacurium chloride (BW B1090U)
    • A short-acting nondepolarizing ester neuromuscular blocking drug
    • Savarese JJ, Ali HH, Basta SJ, etal. The clinical neuromuscular pharmacology of mivacurium chloride (BW B1090U). A short-acting nondepolarizing ester neuromuscular blocking drug. Anesthesiology 1988; 685:723-732.
    • (1988) Anesthesiology , vol.685 , pp. 723-732
    • Savarese, J.J.1    Ali, H.H.2    Basta, S.J.3
  • 10
    • 0025239258 scopus 로고
    • Clinical observations on the neuromuscular blocking action of Org 9426, a new steroidal nondepolarizing agent
    • Wierda JM, de Wit AP, Kuizenga K, et al. Clinical observations on the neuromuscular blocking action of Org 9426, a new steroidal nondepolarizing agent. Br J Anaesth 1990; 644:521-523.
    • (1990) Br J Anaesth , vol.644 , pp. 521-523
    • Wierda, J.M.1    De Wit, A.P.2    Kuizenga, K.3
  • 11
    • 0001229658 scopus 로고
    • Some aspects of the relationship between chemical constitution and curare-like activity
    • Bovet D. Some aspects of the relationship between chemical constitution and curare-like activity. Ann NY Acad Sci 1951; 54:407-437.
    • (1951) Ann NY Acad Sci , vol.54 , pp. 407-437
    • Bovet, D.1
  • 12
    • 0014210379 scopus 로고
    • Alcuronium (Alloferin): A new neuromuscular blocking agent
    • Alcuronium (Alloferin): a new neuromuscular blocking agent. Drug Ther Bull 1967; 517:67-68.
    • (1967) Drug Ther Bull , vol.517 , pp. 67-68
  • 13
    • 0017279357 scopus 로고
    • Studies on fazadinium bromide (ah 8165): A new nondepolarizing neuromuscular blocking agent
    • Hughes R, Payne JP, Sugai N. Studies on fazadinium bromide (ah 8165): a new nondepolarizing neuromuscular blocking agent. Can Anaesth Soc J 1976; 231:36-47.
    • (1976) Can Anaesth Soc J , vol.231 , pp. 36-47
    • Hughes, R.1    Payne, J.P.2    Sugai, N.3
  • 14
    • 0018835859 scopus 로고
    • Pharmacological study of a new competitive neuromuscular blocking steroid, pipecurium bromide
    • Karpati E, Biro K. Pharmacological study of a new competitive neuromuscular blocking steroid, pipecurium bromide. Arzneimittelforschung 1980; 302a: 346-357.
    • (1980) Arzneimittelforschung , vol.302 A , pp. 346-357
    • Karpati, E.1    Biro, K.2
  • 15
    • 0023705968 scopus 로고
    • Clinical pharmacology of doxacurium chloride
    • A new long-acting nondepolarizing muscle relaxant
    • Basta SJ, Savarese JJ, Ali HH, et al. Clinical pharmacology of doxacurium chloride. A new long-acting nondepolarizing muscle relaxant. Anesthesiology 1988; 694:478-486.
    • (1988) Anesthesiology , vol.694 , pp. 478-486
    • Basta, S.J.1    Savarese, J.J.2    Ali, H.H.3
  • 16
    • 0030054611 scopus 로고    scopus 로고
    • Comparative pharmacology of cisatracurium (51W89), atracurium, and five isomers in cats
    • Wastila WB, Maehr RB, Turner GL, et al. Comparative pharmacology of cisatracurium (51W89), atracurium, and five isomers in cats. Anesthesiology 1996; 851:169-177.
    • (1996) Anesthesiology , vol.851 , pp. 169-177
    • Wastila, W.B.1    Maehr, R.B.2    Turner, G.L.3
  • 17
    • 0027272272 scopus 로고
    • Time course of action and endotracheal intubating conditions of Org 9487, a new short-acting steroidal muscle relaxant; A comparison with succinylcholine
    • Wierda JM, van den Broek L, Proost JH, et al. Time course of action and endotracheal intubating conditions of Org 9487, a new short-acting steroidal muscle relaxant; a comparison with succinylcholine. Anesth Analg 1993; 773:579-584.
    • (1993) Anesth Analg , vol.773 , pp. 579-584
    • Wierda, J.M.1    Van Den Broek, L.2    Proost, J.H.3
  • 18
    • 1642392352 scopus 로고    scopus 로고
    • Clinical pharmacology of GW280430A in humans
    • Belmont MR, Lien CA, Tjan J, etal. Clinical pharmacology of GW280430A in humans. Anesthesiology 2004; 1004:768-773.
    • (2004) Anesthesiology , vol.1004 , pp. 768-773
    • Belmont, M.R.1    Lien, C.A.2    Tjan, J.3
  • 20
    • 0037407606 scopus 로고    scopus 로고
    • Residual paralysis in the PACU after a single intubating dose of nondepolarizing muscle relaxant with an intermediate duration of action
    • Debaene B, Plaud B, Dilly MP, et al. Residual paralysis in the PACU after a single intubating dose of nondepolarizing muscle relaxant with an intermediate duration of action. Anesthesiology 2003; 985:1042-1048.
    • (2003) Anesthesiology , vol.985 , pp. 1042-1048
    • Debaene, B.1    Plaud, B.2    Dilly, M.P.3
  • 21
    • 49849100055 scopus 로고    scopus 로고
    • Residual neuromuscular blockade •• and critical respiratory events in the postanesthesia care unit
    • Murphy GS, Szokol JW, Marymont JH, etal. Residual neuromuscular blockade •• and critical respiratory events in the postanesthesia care unit. Anesth Analg 2008; 1071:130-137.
    • (2008) Anesth Analg , vol.1071 , pp. 130-137
    • Murphy, G.S.1    Szokol, J.W.2    Marymont, J.H.3
  • 22
    • 0030730673 scopus 로고    scopus 로고
    • Functional assessment of the pharynx at rest and during swallowing in partially paralyzed humans: Simultaneous videomanometry and mechanomyography of awake human volunteers
    • Eriksson LI, Sundman E, Olsson R, etal. Functional assessment of the pharynx at rest and during swallowing in partially paralyzed humans: simultaneous videomanometry and mechanomyography of awake human volunteers. Anesthesiology 1997; 875:1035-1043.
    • (1997) Anesthesiology , vol.875 , pp. 1035-1043
    • Eriksson, L.I.1    Sundman, E.2    Olsson, R.3
  • 23
    • 0034071051 scopus 로고    scopus 로고
    • The incidence and mechanisms of pharyngeal and upper esophageal dysfunction in partially paralyzed humans: Pharyngeal videoradiography and simultaneous manometry after atracurium
    • Sundman E, Witt H, Olsson R, et al. The incidence and mechanisms of pharyngeal and upper esophageal dysfunction in partially paralyzed humans: pharyngeal videoradiography and simultaneous manometry after atracurium. Anesthesiology 2000; 924:977-984.
    • (2000) Anesthesiology , vol.924 , pp. 977-984
    • Sundman, E.1    Witt, H.2    Olsson, R.3
  • 24
    • 0033009722 scopus 로고    scopus 로고
    • The effects of residual neuromuscular blockade and volatile anesthetics on the control of ventilation
    • Eriksson LI. The effects of residual neuromuscular blockade and volatile anesthetics on the control of ventilation. Anesth Analg 1999; 891:243-251.
    • (1999) Anesth Analg , vol.891 , pp. 243-251
    • Eriksson, L.I.1
  • 25
    • 0023219769 scopus 로고
    • Incomplete reversal of pancuronium neuromuscular blockade by neostigmine, pyridostigmine, and edrophonium
    • Bartkowski RR. Incomplete reversal of pancuronium neuromuscular blockade by neostigmine, pyridostigmine, and edrophonium. Anesth Analg 1987; 667:594-598.
    • (1987) Anesth Analg , vol.667 , pp. 594-598
    • Bartkowski, R.R.1
  • 26
    • 0025732923 scopus 로고
    • Determinants of the reversal time of competitive neuromuscular block by anticholinesterases
    • Beemer GH, Bjorksten AR, Dawson PJ, etal. Determinants of the reversal time of competitive neuromuscular block by anticholinesterases. Br J Anaesth 1991; 664:469-475.
    • (1991) Br J Anaesth , vol.664 , pp. 469-475
    • Beemer, G.H.1    Bjorksten, A.R.2    Dawson, P.J.3
  • 27
    • 49849096107 scopus 로고    scopus 로고
    • Residual neuromuscular block: Rediscovering •• the obvious
    • Brull SJ, Naguib M, Miller RD. Residual neuromuscular block: rediscovering •• the obvious. Anesth Analg 2008; 1071:11-14.
    • (2008) Anesth Analg , vol.1071 , pp. 11-14
    • Brull, S.J.1    Naguib, M.2    Miller, R.D.3
  • 28
    • 12144291015 scopus 로고    scopus 로고
    • Preclinical pharmacology of GW280430A (AV430A) in the rhesus monkey and in the cat: A comparison with mivacurium
    • Savarese JJ, Belmont MR, Hashim MA, et al. Preclinical pharmacology of GW280430A (AV430A) in the rhesus monkey and in the cat: a comparison with mivacurium. Anesthesiology 2004; 1004:835-845.
    • (2004) Anesthesiology , vol.1004 , pp. 835-845
    • Savarese, J.J.1    Belmont, M.R.2    Hashim, M.A.3
  • 29
    • 12444344895 scopus 로고    scopus 로고
    • Neuromuscular blocking activity and therapeutic potential of mixed-tetrahydroisoquinolinium halofumarates and halosuccinates in rhesus monkeys
    • Boros EE, Samano V, Ray JA, et al. Neuromuscular blocking activity and therapeutic potential of mixed-tetrahydroisoquinolinium halofumarates and halosuccinates in rhesus monkeys. J Med Chem 2003; 4612:2502-2515.
    • (2003) J Med Chem , vol.4612 , pp. 2502-2515
    • Boros, E.E.1    Samano, V.2    Ray, J.A.3
  • 30
    • 68949110974 scopus 로고    scopus 로고
    • AV002: A Promising Cysteine-Reversible Intermediate Duration Neuromuscular Blocker in Rhesus Monkeys
    • Savarese JJ, Belmont MR, Kraus K, et al. AV002: A Promising Cysteine-Reversible Intermediate Duration Neuromuscular Blocker in Rhesus Monkeys. ASA Meeting 2007:A986.
    • (2007) ASA Meeting
    • Savarese, J.J.1    Belmont, M.R.2    Kraus, K.3
  • 31
    • 68949145736 scopus 로고    scopus 로고
    • Dose Response Relationship for Cysteine Reversal of the Novel Muscle Relaxant AV002 in Dogs
    • Sunaga H, Malhotora JK, Savarese JJ, etal. Dose Response Relationship for Cysteine Reversal of the Novel Muscle Relaxant AV002 in Dogs. ASA Annual Meeting 2008: A364.
    • (2008) ASA Annual Meeting
    • Sunaga, H.1    Malhotora, J.K.2    Savarese, J.J.3
  • 32
    • 0029032329 scopus 로고
    • Human plasma cholinesterase for antagonism of prolonged mivacurium-induced neuromuscular blockade
    • Naguib M, el-Gammal M, Daoud W, et al. Human plasma cholinesterase for antagonism of prolonged mivacurium-induced neuromuscular blockade. Anesthesiology 1995; 825:1288-1292.
    • (1995) Anesthesiology , vol.825 , pp. 1288-1292
    • Naguib, M.1    El-Gammal, M.2    Daoud, W.3
  • 34
    • 0037127108 scopus 로고    scopus 로고
    • A novel concept of reversing neuromuscular block: Chemical encapsulation of rocuronium bromide by a cyclo-dextrin-based synthetic host
    • Bom A, Bradley M, Cameron K, et al. A novel concept of reversing neuromuscular block: chemical encapsulation of rocuronium bromide by a cyclo-dextrin-based synthetic host. Angew Chem 2002; 412:266-270.
    • (2002) Angew Chem , vol.412 , pp. 266-270
    • Bom, A.1    Bradley, M.2    Cameron, K.3
  • 35
    • 0037171790 scopus 로고    scopus 로고
    • Cyclodextrin-derived host molecules as reversal agents for the neuromuscular blocker rocuronium bromide: Synthesis and structure-activity relationships
    • Adam JM, Bennett DJ, Bom A, et al. Cyclodextrin-derived host molecules as reversal agents for the neuromuscular blocker rocuronium bromide: synthesis and structure-activity relationships. J Med Chem 2002; 459:1806-1816.
    • (2002) J Med Chem , vol.459 , pp. 1806-1816
    • Adam, J.M.1    Bennett, D.J.2    Bom, A.3
  • 36
    • 0036009879 scopus 로고    scopus 로고
    • 2-O-substituted cyclodextrins as reversal agents for the neuromuscular blocker rocuronium bromide
    • Tarver GJ, Grove SJ, Buchanan K, et al. 2-O-substituted cyclodextrins as reversal agents for the neuromuscular blocker rocuronium bromide. Bioorg Med Chem 2002; 106:1819-1827.
    • (2002) Bioorg Med Chem , vol.106 , pp. 1819-1827
    • Tarver, G.J.1    Grove, S.J.2    Buchanan, K.3
  • 37
    • 0037015431 scopus 로고    scopus 로고
    • Modified gamma-cyclodextrins and their rocuronium complexes
    • Accessed 17 November 2008
    • Cameron KS, Clark JK, Cooper A, et al. Modified gamma-cyclodextrins and their rocuronium complexes. Org Lett 2002; 420:3403-3406 www.gangwalchem.com/ CYCLODEXTRIN.html. [Accessed 17 November 2008]
    • (2002) Org Lett , vol.420 , pp. 3403-3406
    • Cameron, K.S.1    Clark, J.K.2    Cooper, A.3
  • 38
    • 31144448393 scopus 로고    scopus 로고
    • Org 25969 (sugammadex), a selective relaxant binding agent for antagonism of prolonged rocuronium-induced neuromuscular block
    • Shields M, Giovannelli M, Mirakhur RK, et al. Org 25969 (sugammadex), a selective relaxant binding agent for antagonism of prolonged rocuronium-induced neuromuscular block. Br J Anaesth 2006; 961:36-43.
    • (2006) Br J Anaesth , vol.961 , pp. 36-43
    • Shields, M.1    Giovannelli, M.2    Mirakhur, R.K.3
  • 39
    • 33645646481 scopus 로고    scopus 로고
    • Reversal of rocuronium-induced neuromuscular block by the selective relaxant binding agent sugammadex: A dose-finding and safety study
    • Sorgenfrei IF, Norrild K, Larsen PB, et al. Reversal of rocuronium-induced neuromuscular block by the selective relaxant binding agent sugammadex: a dose-finding and safety study. Anesthesiology 2006; 1044:667-674.
    • (2006) Anesthesiology , vol.1044 , pp. 667-674
    • Sorgenfrei, I.F.1    Norrild, K.2    Larsen, P.B.3
  • 40
    • 33847235862 scopus 로고    scopus 로고
    • Sugammadex: Another milestone in clinical neuromuscular pharmacology
    • Naguib M. Sugammadex: another milestone in clinical neuromuscular pharmacology. Anesth Analg 2007; 1043:575-581.
    • (2007) Anesth Analg , vol.1043 , pp. 575-581
    • Naguib, M.1
  • 41
    • 0041324616 scopus 로고    scopus 로고
    • Reversal of neuromuscular blockade and simultaneous increase in plasma rocuronium concentration after the intravenous infusion of the novel reversal agent Org 25969.
    • Epemolu O, Bom A, Hope F, et al. Reversal of neuromuscular blockade and simultaneous increase in plasma rocuronium concentration after the intravenous infusion of the novel reversal agent Org 25969. Anesthesiology 2003; 993:632-637.
    • (2003) Anesthesiology , vol.993 , pp. 632-637
    • Epemolu, O.1    Bom, A.2    Hope, F.3
  • 42
    • 37349022783 scopus 로고    scopus 로고
    • Sugammadex may replace best clinical practice: A misconception
    • Naguib M. Sugammadex may replace best clinical practice: a misconception. Anesth Analg 2007; 1055:1506-a-1507.
    • (2007) Anesth Analg , vol.1055 , pp. 1506-1507
    • Naguib, M.1
  • 43
    • 26244449246 scopus 로고    scopus 로고
    • First human exposure of Org 25969, a novel agent to reverse the action of rocuronium bromide
    • Gijsenbergh F, Ramael S, Houwing N, et al. First human exposure of Org 25969, a novel agent to reverse the action of rocuronium bromide. Anesthesiology 2005; 1034:695-703.
    • (2005) Anesthesiology , vol.1034 , pp. 695-703
    • Gijsenbergh, F.1    Ramael, S.2    Houwing, N.3
  • 44
    • 31744446580 scopus 로고    scopus 로고
    • Chemical encapsulation of rocuronium by synthetic cyclodextrin derivatives: Reversal of neuromuscular block in anaesthetized Rhesus monkeys
    • de Boer HD, van Egmond J, van de Pol F, et al. Chemical encapsulation of rocuronium by synthetic cyclodextrin derivatives: reversal of neuromuscular block in anaesthetized Rhesus monkeys. Br J Anaesth 2006; 962:201-206.
    • (2006) Br J Anaesth , vol.962 , pp. 201-206
    • De Boer, H.D.1    Van Egmond, J.2    Van De Pol, F.3
  • 45
    • 33645646584 scopus 로고    scopus 로고
    • Reversal of profound rocuronium neuromuscular blockade by sugammadex in anesthetized rhesus monkeys
    • de Boer HD, van Egmond J, van de Pol F, et al. Reversal of profound rocuronium neuromuscular blockade by sugammadex in anesthetized rhesus monkeys. Anesthesiology 2006; 1044:718-723.
    • (2006) Anesthesiology , vol.1044 , pp. 718-723
    • De Boer, H.D.1    Van Egmond, J.2    Van De Pol, F.3
  • 46
    • 33645289950 scopus 로고    scopus 로고
    • Sugammadex, a new reversal agent for neuromuscular block induced by rocuronium in the anaesthetized Rhesus monkey
    • de Boer HD, van Egmond J, van de Pol F, et al. Sugammadex, a new reversal agent for neuromuscular block induced by rocuronium in the anaesthetized Rhesus monkey. Br J Anaesth 2006; 964:473-479.
    • (2006) Br J Anaesth , vol.964 , pp. 473-479
    • De Boer, H.D.1    Van Egmond, J.2    Van De Pol, F.3
  • 47
    • 33847218979 scopus 로고    scopus 로고
    • A temporary decrease in twitch response during reversal of rocuronium-induced muscle relaxation with a small dose of sugammadex
    • Eleveld DJ, Kuizenga K, Proost JH, et al. A temporary decrease in twitch response during reversal of rocuronium-induced muscle relaxation with a small dose of sugammadex. Anesth Analg 2007; 1043:582-584.
    • (2007) Anesth Analg , vol.1043 , pp. 582-584
    • Eleveld, D.J.1    Kuizenga, K.2    Proost, J.H.3
  • 48
    • 0038234979 scopus 로고    scopus 로고
    • Drug-specific cyclodextrins: The future of rapid neuromuscular block reversal?
    • Zhang MQ. Drug-specific cyclodextrins: the future of rapid neuromuscular block reversal? Drugs Future 2003; 28:347-354.
    • (2003) Drugs Future , vol.28 , pp. 347-354
    • Zhang, M.Q.1
  • 49
    • 68949106591 scopus 로고    scopus 로고
    • Accessed 10 November 2008
    • http://www.emea.europa.eu/humandocs/PDFs/EPAR/bridion/H-885-PI-en.pdf. [Accessed 10 November 2008]
  • 50
    • 0033759804 scopus 로고    scopus 로고
    • Urinary, biliary and faecal excretion of rocuronium in humans
    • Proost JH, Eriksson LI, Mirakhur RK, et al. Urinary, biliary and faecal excretion of rocuronium in humans. Br J Anaesth 2000; 855:717-723.
    • (2000) Br J Anaesth , vol.855 , pp. 717-723
    • Proost, J.H.1    Eriksson, L.I.2    Mirakhur, R.K.3
  • 51
    • 34247584581 scopus 로고    scopus 로고
    • Early reversal of profound rocuronium-induced neuromuscular blockade by sugammadex in a randomized multicenter study: Efficacy, safety, and pharmacokinetics
    • Sparr HJ, Vermeyen KM, Beaufort AM, et al. Early reversal of profound rocuronium-induced neuromuscular blockade by sugammadex in a randomized multicenter study: efficacy, safety, and pharmacokinetics. Anesthesiology 2007; 1065:935-943.
    • (2007) Anesthesiology , vol.1065 , pp. 935-943
    • Sparr, H.J.1    Vermeyen, K.M.2    Beaufort, A.M.3
  • 53
    • 68949131794 scopus 로고    scopus 로고
    • Sugammadex: A novel selective relaxant binding agent
    • Naguib M, Brull SJ. Sugammadex: a novel selective relaxant binding agent. Expert Rev Clin Pharmacol 2009; 2:37-53.
    • (2009) Expert Rev Clin Pharmacol , vol.2 , pp. 37-53
    • Naguib, M.1    Brull, S.J.2
  • 54
    • 0025357547 scopus 로고
    • Role of the transsulfuration pathway and of gamma-cystathionase activity in the formation of cysteine and sulfate from methionine in rat hepatocytes
    • Rao AM, Drake MR, Stipanuk MH. Role of the transsulfuration pathway and of gamma-cystathionase activity in the formation of cysteine and sulfate from methionine in rat hepatocytes. J Nutr 1990; 1208:837-845.
    • (1990) J Nutr , vol.1208 , pp. 837-845
    • Rao, A.M.1    Drake, M.R.2    Stipanuk, M.H.3
  • 55
    • 0025733478 scopus 로고
    • Formation, nutritional value, and safety of D-amino acids
    • Friedman M. Formation, nutritional value, and safety of D-amino acids. Adv Exp Med Biol 1991; 289:447-481.
    • (1991) Adv Exp Med Biol , vol.289 , pp. 447-481
    • Friedman, M.1
  • 56
    • 3142729014 scopus 로고    scopus 로고
    • Sulfur amino acid metabolism: Pathways for production and removal of homocysteine and cysteine
    • Stipanuk MH. Sulfur amino acid metabolism: pathways for production and removal of homocysteine and cysteine. Annu Rev Nutr 2004; 24:539-577.
    • (2004) Annu Rev Nutr , vol.24 , pp. 539-577
    • Stipanuk, M.H.1
  • 57
    • 0025127781 scopus 로고
    • Effect of bathocuproine disulfonate, a copper chelator, on cyst(e)ine metabolism by freshly isolated rat hepatocytes
    • Coloso RM, Drake MR, Stipanuk MH. Effect of bathocuproine disulfonate, a copper chelator, on cyst(e)ine metabolism by freshly isolated rat hepatocytes. Am J Physiol 1990; 2593 (Pt 1):E443-450.
    • (1990) Am J Physiol , vol.2593 , Issue.PART 1
    • Coloso, R.M.1    Drake, M.R.2    Stipanuk, M.H.3
  • 58
    • 0023796961 scopus 로고
    • In vivo studies of cysteine metabolism. Use of D-cysteinesulfinate, a novel cysteinesulfinate decarbox-ylase inhibitor, to probe taurine and pyruvate synthesis
    • Weinstein CL, Haschemeyer RH, Griffith OW. In vivo studies of cysteine metabolism. Use of D-cysteinesulfinate, a novel cysteinesulfinate decarbox-ylase inhibitor, to probe taurine and pyruvate synthesis. J Biol Chem 1988; 26332:16568-16579.
    • (1988) J Biol Chem , pp. 16568-16579
    • Weinstein, C.L.1    Haschemeyer, R.H.2    Griffith, O.W.3
  • 59
    • 0036449317 scopus 로고    scopus 로고
    • A study on the estimation of sulfur-containing amino acid metabolism by the determination of urinary sulfate and taurine
    • Nakamura H, Kajikawa R, Ubuka T. A study on the estimation of sulfur-containing amino acid metabolism by the determination of urinary sulfate and taurine. Amino Acids 2002; 234:427-431.
    • (2002) Amino Acids , vol.234 , pp. 427-431
    • Nakamura, H.1    Kajikawa, R.2    Ubuka, T.3
  • 60
    • 77950859766 scopus 로고    scopus 로고
    • The Dose-Response for Immediate Reversal of AV 002 by Cysteine in the Rhesus Monkey
    • Savarese JJ, Belmont MR, savard PR, et al. The Dose-Response for Immediate Reversal of AV 002 by Cysteine in the Rhesus Monkey. ASA Annual Meeting 2008:A1403.
    • (2008) ASA Annual Meeting
    • Savarese, J.J.1    Belmont, M.R.2    Savard, P.R.3
  • 61
    • 77953659612 scopus 로고    scopus 로고
    • Cardiovascular Effects of Cysteine Used for Reversal of Novel Neuromuscular Blocking Drugs in Dogs
    • Sunaga H, Malhotora JK, Savarese JJ, etal. Cardiovascular Effects of Cysteine Used for Reversal of Novel Neuromuscular Blocking Drugs in Dogs. ASA Annual Meeting 2008:A367.
    • (2008) ASA Annual Meeting
    • Sunaga, H.1    Malhotora, J.K.2    Savarese, J.J.3
  • 62
    • 0014937190 scopus 로고
    • Ho OL Brain damage in infant mice following oral intake of glutamate, aspartate or cysteine
    • Olney JW, Ho OL Brain damage in infant mice following oral intake of glutamate, aspartate or cysteine. Nature 1970 2275258: 609-611.
    • (1970) Nature , pp. 609-611
    • Olney, J.W.1
  • 63
    • 0015504993 scopus 로고
    • Cysteine-induced brain damage in infant and fetal rodents
    • Olney JW, Ho OL, Rhee V, etal. Cysteine-induced brain damage in infant and fetal rodents. Brain Res 1972; 451:309-313.
    • (1972) Brain Res , vol.451 , pp. 309-313
    • Olney, J.W.1    Ho, O.L.2    Rhee, V.3
  • 64
    • 0019434206 scopus 로고
    • Morphological changes in rat brain induced by L-cysteine injection in newborn animals
    • Karlsen RL, Grofova I, Malthe-Sorenssen D, et al. Morphological changes in rat brain induced by L-cysteine injection in newborn animals. Brain Res 1981; 2081:167-180.
    • (1981) Brain Res , vol.2081 , pp. 167-180
    • Karlsen, R.L.1    Grofova, I.2    Malthe-Sorenssen, D.3
  • 65
    • 0024598233 scopus 로고
    • Is A Certain Amount of Cysteine Prerequisite to Produce Brain Damage in Neonatal Rats
    • Misra CH. Is a certain amount of cysteine prerequisite to produce brain damage in neonatal rats? Neurochem Res 1989; 143:253-257.
    • (1989) Neurochem Res , vol.143 , pp. 253-257
    • Misra, C.H.1
  • 66
    • 0029000510 scopus 로고
    • Toxicity of sulphur-containing compounds to neuronal cell lines
    • Pean AR, Parsons RB, Waring RH, et al. Toxicity of sulphur-containing compounds to neuronal cell lines. J Neurol Sci 1995; 129 (Suppl):107-108.
    • (1995) J Neurol Sci , vol.129 , Issue.SUPPL , pp. 107-108
    • Pean, A.R.1    Parsons, R.B.2    Waring, R.H.3
  • 67
    • 0016799601 scopus 로고
    • Brain damage and associated behavioral deficits following the administration of L-cysteine to infant rats
    • Shapre LG, Olney JW, Ohlendorf C, et al. Brain damage and associated behavioral deficits following the administration of L-cysteine to infant rats. Pharmacol Biochem Behav 1975; 32:291-298.
    • (1975) Pharmacol Biochem Behav , vol.32 , pp. 291-298
    • Shapre, L.G.1    Olney, J.W.2    Ohlendorf, C.3
  • 68
    • 0027461450 scopus 로고
    • Autoxidation of cysteine generates hydrogen peroxide: Cytotoxicity and attenuation by pyruvate
    • Nath KA, Salahudeen AK. Autoxidation of cysteine generates hydrogen peroxide: cytotoxicity and attenuation by pyruvate. Am J Physiol 1993; 2642 (Pt2):F306-314.
    • (1993) Am J Physiol , vol.2642 , Issue.PART 2
    • Nath, K.A.1    Salahudeen, A.K.2
  • 69
    • 0034305689 scopus 로고    scopus 로고
    • Mechanisms of L-cysteine neurotoxicity
    • Janaky R, Varga V, Hermann A, et al. Mechanisms of L-cysteine neurotoxicity. Neurochem Res 2000; 259-10:1397-1405.
    • (2000) Neurochem Res , vol.259 , Issue.10 , pp. 1397-1405
    • Janaky, R.1    Varga, V.2    Hermann, A.3
  • 70
    • 1942519353 scopus 로고    scopus 로고
    • Cysteine-induced hypoglycemic brain damage: An alternative mechanism to excitotoxicity
    • Gazit V, Ben-Abraham R, Coleman R, et al. Cysteine-induced hypoglycemic brain damage: an alternative mechanism to excitotoxicity. Amino Acids 2004; 262:163-168.
    • (2004) Amino Acids , vol.262 , pp. 163-168
    • Gazit, V.1    Ben-Abraham, R.2    Coleman, R.3
  • 71
    • 0026052866 scopus 로고
    • Cysteine usage increases the need for acetate in neonates who receive total parenteral nutrition
    • Laine L, Shulman RJ, Pitre D, et al. Cysteine usage increases the need for acetate in neonates who receive total parenteral nutrition. Am J Clin Nutr 1991; 543:565-567.
    • (1991) Am J Clin Nutr , vol.543 , pp. 565-567
    • Laine, L.1    Shulman, R.J.2    Pitre, D.3
  • 72
    • 31444434248 scopus 로고    scopus 로고
    • Postoperative residual paralysis in outpatients versus inpatients
    • Cammu G, De Witte J, De Veylder J, etal. Postoperative residual paralysis in outpatients versus inpatients. Anesth Analg 2006; 1022:426-429.
    • (2006) Anesth Analg , vol.1022 , pp. 426-429
    • Cammu, G.1    De Witte, J.2    De Veylder, J.3
  • 73
    • 0030469824 scopus 로고    scopus 로고
    • Residual postoperative paralysis
    • Pancur-onium versus mivacurium, does it matter
    • Kopman AF, Ng J, Zank LM, et al. Residual postoperative paralysis. Pancur-onium versus mivacurium, does it matter? Anesthesiology 1996; 856:1253-1259.
    • (1996) Anesthesiology , vol.856 , pp. 1253-1259
    • Kopman, A.F.1    Ng, J.2    Zank, L.M.3


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