Reversal of neuromuscular blockade and simultaneous increase in plasma rocuronium concentration after the intravenous infusion of the novel reversal agent Org 25969

Anesthesiology

Volumn 99, Issue 3, 2003, Pages 632-637

  Epemolu, Ola ^a   Bom, Anton ^b   Hope, Frank ^b   Mason, Rona ^b  

^a MERCK RESEARCH LABORATORIES   (United States)

^b NONE

Author keywords

[No Author keywords available]

Indexed keywords

GAMMA CYCLODEXTRIN DERIVATIVE; NEUROMUSCULAR BLOCKING AGENT; ORG 25959; ROCURONIUM; SODIUM CHLORIDE; SUGAMMADEX; UNCLASSIFIED DRUG;

ANIMAL EXPERIMENT; ARTICLE; AUTOPSY; BODY WEIGHT; CONTROLLED STUDY; DRUG BLOOD LEVEL; DRUG URINE LEVEL; GASTROCNEMIUS MUSCLE; GUINEA PIG; HEART RATE; LIQUID CHROMATOGRAPHY; MALE; MASS SPECTROMETRY; MEAN ARTERIAL PRESSURE; MUSCLE TWITCH; NEUROMUSCULAR BLOCKING; NEUROMUSCULAR SYNAPSE; NONHUMAN; PRIORITY JOURNAL; STEADY STATE;

ANDROSTANOLS; ANESTHESIA; ANIMALS; BLOOD PRESSURE; BODY WEIGHT; CHROMATOGRAPHY, HIGH PRESSURE LIQUID; CYCLODEXTRINS; GAMMA-CYCLODEXTRINS; GUINEA PIGS; HEART RATE; INFUSIONS, INTRAVENOUS; MALE; MASS SPECTROMETRY; MUSCLE CONTRACTION; NEUROMUSCULAR NONDEPOLARIZING AGENTS; VEHICLES;

EID: 0041324616     PISSN: 00033022     EISSN: None     Source Type: Journal    
DOI: 10.1097/00000542-200309000-00018     Document Type: Article

References (13)

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5. Mason R, Bom A: Org 25969 causes selective reversal of neuromuscular block induced steroidal NMBs in anaesthetised guinea pigs (abstract 18). Eur J Anaesthesiol 2001; 18(suppl 23):100
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