메뉴 건너뛰기




Volumn , Issue , 2009, Pages

Anti-EGFR-targeted therapy for esophageal and gastric cancers: An evolving concept

Author keywords

[No Author keywords available]

Indexed keywords

ADENOSINE TRIPHOSPHATE; CAPECITABINE; CARBOPLATIN; CETUXIMAB; CISPLATIN; DOCETAXEL; DOXORUBICIN; EPIDERMAL GROWTH FACTOR RECEPTOR; EPIDERMAL GROWTH FACTOR RECEPTOR KINASE INHIBITOR; EPIRUBICIN; ERLOTINIB; ETOPOSIDE; FLUOROURACIL; FOLINIC ACID; GEFITINIB; IRINOTECAN; LAPATINIB; NAVELBINE; OXALIPLATIN; PACLITAXEL; PANITUMUMAB;

EID: 68949109786     PISSN: 16878450     EISSN: 16878469     Source Type: Journal    
DOI: 10.1155/2009/804108     Document Type: Review
Times cited : (43)

References (59)
  • 3
    • 43249095213 scopus 로고    scopus 로고
    • Chemotherapy for metastatic gastric cancer: Past, present, and future
    • Ohtsu A., Chemotherapy for metastatic gastric cancer: past, present, and future Journal of Gastroenterology 2008 43 4 256 264
    • (2008) Journal of Gastroenterology , vol.43 , Issue.4 , pp. 256-264
    • Ohtsu, A.1
  • 4
    • 0032756946 scopus 로고    scopus 로고
    • The changing epidemiology of esophageal cancer
    • Blot W. J., McLaughlin J. K., The changing epidemiology of esophageal cancer Seminars in Oncology 1999 26 5, supplement 15 2 8
    • (1999) Seminars in Oncology , vol.26 , Issue.5 SUPPLEMENT 15 , pp. 2-8
    • Blot, W.J.1    McLaughlin, J.K.2
  • 5
    • 0033580405 scopus 로고    scopus 로고
    • Symptomatic gastroesophageal reflux as a risk factor for esophageal adenocarcinoma
    • Lagergren J., Bergstrm R., Lindgren A., Nyrn O., Symptomatic gastroesophageal reflux as a risk factor for esophageal adenocarcinoma The New England Journal of Medicine 1999 340 11 825 831
    • (1999) The New England Journal of Medicine , vol.340 , Issue.11 , pp. 825-831
    • Lagergren, J.1    Bergstrm, R.2    Lindgren, A.3    Nyrn, O.4
  • 7
    • 0025676478 scopus 로고
    • Helicobacter pylori and gastric carcinoma. Serum antibody prevalence in populations with contrasting cancer risks
    • Correa P., Fox J., Fontham E., Helicobacter pylori and gastric carcinoma. Serum antibody prevalence in populations with contrasting cancer risks Cancer 1990 66 12 2569 2574
    • (1990) Cancer , vol.66 , Issue.12 , pp. 2569-2574
    • Correa, P.1    Fox, J.2    Fontham, E.3
  • 8
    • 35348826772 scopus 로고    scopus 로고
    • A phase II study of gefitinib monotherapy in advanced esophageal adenocarcinoma: Evidence of gene expression, cellular, and clinical response
    • Ferry D. R., Anderson M., Beddard K., A phase II study of gefitinib monotherapy in advanced esophageal adenocarcinoma: evidence of gene expression, cellular, and clinical response Clinical Cancer Research 2007 13 19 5869 5875
    • (2007) Clinical Cancer Research , vol.13 , Issue.19 , pp. 5869-5875
    • Ferry, D.R.1    Anderson, M.2    Beddard, K.3
  • 9
    • 33645734242 scopus 로고    scopus 로고
    • Predictive factors for outcome in a phase II study of gefitinib in second-line treatment of advanced esophageal cancer patients
    • Janmaat M. L., Gallegos-Ruiz M. I., Rodriguez J. A., Predictive factors for outcome in a phase II study of gefitinib in second-line treatment of advanced esophageal cancer patients Journal of Clinical Oncology 2006 24 10 1612 1619
    • (2006) Journal of Clinical Oncology , vol.24 , Issue.10 , pp. 1612-1619
    • Janmaat, M.L.1    Gallegos-Ruiz, M.I.2    Rodriguez, J.A.3
  • 10
    • 33750618860 scopus 로고    scopus 로고
    • Phase II trial of erlotinib in gastroesophageal junction and gastric adenocarcinomas: SWOG 0127
    • Dragovich T., McCoy S., Fenoglio-Preiser C. M., Phase II trial of erlotinib in gastroesophageal junction and gastric adenocarcinomas: SWOG 0127 Journal of Clinical Oncology 2006 24 30 4922 4927
    • (2006) Journal of Clinical Oncology , vol.24 , Issue.30 , pp. 4922-4927
    • Dragovich, T.1    McCoy, S.2    Fenoglio-Preiser, C.M.3
  • 13
    • 33646418733 scopus 로고    scopus 로고
    • Cetuximab approved by FDA for treatment of head and neck squamous cell cancer
    • Cetuximab approved by FDA for treatment of head and neck squamous cell cancer Cancer Biology Therapy 2006 5 4 340 342
    • (2006) Cancer Biology Therapy , vol.5 , Issue.4 , pp. 340-342
  • 16
    • 47249146141 scopus 로고    scopus 로고
    • Lessons from Tarceva in pancreatic cancer: Where are we now, and how should future trials be designed in pancreatic cancer?
    • Laurent-Puig P., Taieb J., Lessons from Tarceva in pancreatic cancer: where are we now, and how should future trials be designed in pancreatic cancer? Current Opinion in Oncology 2008 20 4 454 458
    • (2008) Current Opinion in Oncology , vol.20 , Issue.4 , pp. 454-458
    • Laurent-Puig, P.1    Taieb, J.2
  • 17
    • 34347393724 scopus 로고    scopus 로고
    • Therapies directed against epidermal growth factor receptor in aerodigestive carcinomas
    • Karamouzis M. V., Grandis J. R., Argiris A., Therapies directed against epidermal growth factor receptor in aerodigestive carcinomas Journal of the American Medical Association 2007 298 1 70 82
    • (2007) Journal of the American Medical Association , vol.298 , Issue.1 , pp. 70-82
    • Karamouzis, M.V.1    Grandis, J.R.2    Argiris, A.3
  • 19
    • 18344390418 scopus 로고    scopus 로고
    • ERBB receptors and cancer: The complexity of targeted inhibitors
    • Hynes N. E., Lane H. A., ERBB receptors and cancer: the complexity of targeted inhibitors Nature Reviews Cancer 2005 5 5 341 354
    • (2005) Nature Reviews Cancer , vol.5 , Issue.5 , pp. 341-354
    • Hynes, N.E.1    Lane, H.A.2
  • 20
    • 21744451378 scopus 로고    scopus 로고
    • Erratum: ERBB receptors and cancer: The complexity of targeted inhibitors
    • Hynes N. E., Lane H. A., Erratum: ERBB receptors and cancer: the complexity of targeted inhibitors Nature Reviews Cancer 2005 5 7 580
    • (2005) Nature Reviews Cancer , vol.5 , Issue.7 , pp. 580
    • Hynes, N.E.1    Lane, H.A.2
  • 21
    • 55249111472 scopus 로고    scopus 로고
    • Cetuximab as second-line therapy in patients with metastatic esophageal cancer: A phase II Southwest Oncology Group Study
    • abstract no. 4536
    • Gold P. J., Goldman B., Iqbal S., Cetuximab as second-line therapy in patients with metastatic esophageal cancer: a phase II Southwest Oncology Group Study Proceedings of the American Society of Clinical Oncology Annual Meeting 2008. abstract no. 4536
    • (2008) Proceedings of the American Society of Clinical Oncology Annual Meeting
    • Gold, P.J.1    Goldman, B.2    Iqbal, S.3
  • 23
    • 33847663871 scopus 로고    scopus 로고
    • Phase II study of cetuximab in combination with FOLFIRI in patients with untreated advanced gastric or gastroesophageal junction adenocarcinoma (FOLCETUX study)
    • Pinto C., Di Fabio F., Siena S., Phase II study of cetuximab in combination with FOLFIRI in patients with untreated advanced gastric or gastroesophageal junction adenocarcinoma (FOLCETUX study) Annals of Oncology 2007 18 3 510 517
    • (2007) Annals of Oncology , vol.18 , Issue.3 , pp. 510-517
    • Pinto, C.1    Di Fabio, F.2    Siena, S.3
  • 24
    • 58749089260 scopus 로고    scopus 로고
    • Phase II study and biomarker analysis of cetuximab combined with modified FOLFOX6 in advanced gastric cancer
    • Han S.-W., Oh D.-Y., Im S.-A., Phase II study and biomarker analysis of cetuximab combined with modified FOLFOX6 in advanced gastric cancer British Journal of Cancer 2009 100 2 298 304
    • (2009) British Journal of Cancer , vol.100 , Issue.2 , pp. 298-304
    • Han, S.-W.1    Oh, D.-Y.2    Im, S.-A.3
  • 25
    • 33747855481 scopus 로고    scopus 로고
    • Comparing antibody and small-molecule therapies for cancer
    • Imai K., Takaoka A., Comparing antibody and small-molecule therapies for cancer Nature Reviews Cancer 2006 6 9 714 727
    • (2006) Nature Reviews Cancer , vol.6 , Issue.9 , pp. 714-727
    • Imai, K.1    Takaoka, A.2
  • 26
    • 19244366949 scopus 로고    scopus 로고
    • Phase i studies of anti-epidermal growth factor receptor chimeric antibody C225 alone and in combination with cisplatin
    • Baselga J., Pfister D., Cooper M. R., Phase I studies of anti-epidermal growth factor receptor chimeric antibody C225 alone and in combination with cisplatin Journal of Clinical Oncology 2000 18 4 904 914
    • (2000) Journal of Clinical Oncology , vol.18 , Issue.4 , pp. 904-914
    • Baselga, J.1    Pfister, D.2    Cooper, M.R.3
  • 27
    • 40349087139 scopus 로고    scopus 로고
    • Administration of cetuximab every 2 weeks in the treatment of metastatic colorectal cancer: An effective, more convenient alternative to weekly administration?
    • Tabernero J., Pfeiffer P., Cervantes A., Administration of cetuximab every 2 weeks in the treatment of metastatic colorectal cancer: an effective, more convenient alternative to weekly administration? The Oncologist 2008 13 2 113 119
    • (2008) The Oncologist , vol.13 , Issue.2 , pp. 113-119
    • Tabernero, J.1    Pfeiffer, P.2    Cervantes, A.3
  • 28
    • 33749018219 scopus 로고    scopus 로고
    • Mechanisms of cutaneous toxicities to EGFR inhibitors
    • Lacouture M. E., Mechanisms of cutaneous toxicities to EGFR inhibitors Nature Reviews Cancer 2006 6 10 803 812
    • (2006) Nature Reviews Cancer , vol.6 , Issue.10 , pp. 803-812
    • Lacouture, M.E.1
  • 29
    • 0001412078 scopus 로고    scopus 로고
    • Acne-like rash predicts response in patients treated with cetuximab (IMC-C225) pluls irinotecan (CPT-11) in CPT-11 refractory colorectal cancer (CRC) that expresses epidermal growth factor receptor (EGFR)
    • abstract no. 559
    • Saltz L., Rubin M. S., Hochster H., Acne-like rash predicts response in patients treated with cetuximab (IMC-C225) pluls irinotecan (CPT-11) in CPT-11 refractory colorectal cancer (CRC) that expresses epidermal growth factor receptor (EGFR) Clinical Cancer Research 2001 7 3766s. abstract no. 559
    • (2001) Clinical Cancer Research , vol.7
    • Saltz, L.1    Rubin, M.S.2    Hochster, H.3
  • 30
    • 34447129570 scopus 로고    scopus 로고
    • Correlation between development of rash and efficacy in patients treated with the epidermal growth factor receptor tyrosine kinase inhibitor erlotinib in two large phase III studies
    • Wacker B., Nagrani T., Weinberg J., Witt K., Clark G., Cagnoni P. J., Correlation between development of rash and efficacy in patients treated with the epidermal growth factor receptor tyrosine kinase inhibitor erlotinib in two large phase III studies Clinical Cancer Research 2007 13 13 3913 3921
    • (2007) Clinical Cancer Research , vol.13 , Issue.13 , pp. 3913-3921
    • Wacker, B.1    Nagrani, T.2    Weinberg, J.3    Witt, K.4    Clark, G.5    Cagnoni, P.J.6
  • 31
    • 1842772526 scopus 로고    scopus 로고
    • Multicenter phase II study of erlotinib, an oral epidermal growth factor receptor tyrosine kinase inhibitor, in patients with recurrent or metastatic squamous cell cancer of the head and neck
    • Soulieres D., Senzer N. N., Vokes E. E., Hidalgo M., Agarvala S. S., Siu L. L., Multicenter phase II study of erlotinib, an oral epidermal growth factor receptor tyrosine kinase inhibitor, in patients with recurrent or metastatic squamous cell cancer of the head and neck Journal of Clinical Oncology 2004 22 1 77 85
    • (2004) Journal of Clinical Oncology , vol.22 , Issue.1 , pp. 77-85
    • Soulieres, D.1    Senzer, N.N.2    Vokes, E.E.3    Hidalgo, M.4    Agarvala, S.S.5    Siu, L.L.6
  • 32
    • 28944439741 scopus 로고    scopus 로고
    • Efficacy and safety of erlotinib HCl, an epidermal growth factor receptor (HER1/EGFR) tyrosine kinase inhibitor, in patients with advanced ovarian carcinoma: Results from a phase II multicenter study
    • Gordon A. N., Finkler N., Edwards R. P., Efficacy and safety of erlotinib HCl, an epidermal growth factor receptor (HER1/EGFR) tyrosine kinase inhibitor, in patients with advanced ovarian carcinoma: results from a phase II multicenter study International Journal of Gynecological Cancer 2005 15 5 785 792
    • (2005) International Journal of Gynecological Cancer , vol.15 , Issue.5 , pp. 785-792
    • Gordon, A.N.1    Finkler, N.2    Edwards, R.P.3
  • 33
    • 36949037220 scopus 로고    scopus 로고
    • Phase I/II study of cetuximab dose-escalation in patients with metastatic colorectal cancer (mCRC) with no or slight skin reactions on cetuximab standard dose treatment (EVEREST): Pharmacokinetic (PK), pharmacodynamic (PD) and efficacy data
    • abstract no. 4037
    • Tejpar S., Peeters M., Humblet Y., Phase I/II study of cetuximab dose-escalation in patients with metastatic colorectal cancer (mCRC) with no or slight skin reactions on cetuximab standard dose treatment (EVEREST): pharmacokinetic (PK), pharmacodynamic (PD) and efficacy data Journal of Clinical Oncology 2007 25 18, supplement. abstract no. 4037
    • (2007) Journal of Clinical Oncology , vol.25 , Issue.18 SUPPLEMENT
    • Tejpar, S.1    Peeters, M.2    Humblet, Y.3
  • 35
    • 0030789850 scopus 로고    scopus 로고
    • Randomised phase II study of cisplatin and 5-fluorouracil (5-FU) versus cisplatin alone in advanced squamous cell oesophageal cancer
    • Bleiberg H., Conroy T., Paillot B., Randomised phase II study of cisplatin and 5-fluorouracil (5-FU) versus cisplatin alone in advanced squamous cell oesophageal cancer European Journal of Cancer 1997 33 8 1216 1220
    • (1997) European Journal of Cancer , vol.33 , Issue.8 , pp. 1216-1220
    • Bleiberg, H.1    Conroy, T.2    Paillot, B.3
  • 36
    • 0031831196 scopus 로고    scopus 로고
    • Phase II trial of paclitaxel, fluorouracil, and cisplatin in patients with advanced carcinoma of the esophagus
    • Ilson D. H., Ajani J., Bhalla K., Phase II trial of paclitaxel, fluorouracil, and cisplatin in patients with advanced carcinoma of the esophagus Journal of Clinical Oncology 1998 16 5 1826 1834
    • (1998) Journal of Clinical Oncology , vol.16 , Issue.5 , pp. 1826-1834
    • Ilson, D.H.1    Ajani, J.2    Bhalla, K.3
  • 37
    • 0033764273 scopus 로고    scopus 로고
    • A phase II trial of paclitaxel and cisplatin in patients with advanced carcinoma of the esophagus
    • Ilson D. H., Forastiere A., Arquette M., A phase II trial of paclitaxel and cisplatin in patients with advanced carcinoma of the esophagus Cancer Journal 2000 6 5 316 323
    • (2000) Cancer Journal , vol.6 , Issue.5 , pp. 316-323
    • Ilson, D.H.1    Forastiere, A.2    Arquette, M.3
  • 38
    • 0031825774 scopus 로고    scopus 로고
    • Chemotherapy with cisplatin and paclitaxel in patients with locally advanced, recurrent or metastatic oesophageal cancer
    • Petrasch S., Welt A., Reinacher A., Graeven U., Knig M., Schmiegel W., Chemotherapy with cisplatin and paclitaxel in patients with locally advanced, recurrent or metastatic oesophageal cancer British Journal of Cancer 1998 78 4 511 514
    • (1998) British Journal of Cancer , vol.78 , Issue.4 , pp. 511-514
    • Petrasch, S.1    Welt, A.2    Reinacher, A.3    Graeven, U.4    Knig, M.5    Schmiegel, W.6
  • 39
    • 0032887574 scopus 로고    scopus 로고
    • Phase II trial of weekly irinotecan plus cisplatin in advanced esophageal cancer
    • Ilson D. H., Saltz L., Enzinger P., Phase II trial of weekly irinotecan plus cisplatin in advanced esophageal cancer Journal of Clinical Oncology 1999 17 10 3270 3275
    • (1999) Journal of Clinical Oncology , vol.17 , Issue.10 , pp. 3270-3275
    • Ilson, D.H.1    Saltz, L.2    Enzinger, P.3
  • 40
    • 0029737060 scopus 로고    scopus 로고
    • Cisplatin and etoposide in oesophageal cancer: A phase II study. Rotterdam Oesophageal Tumour Study Group
    • Kok T. C., van der Gaast A., Dees J., Cisplatin and etoposide in oesophageal cancer: a phase II study. Rotterdam Oesophageal Tumour Study Group British Journal of Cancer 1996 74 6 980 984
    • (1996) British Journal of Cancer , vol.74 , Issue.6 , pp. 980-984
    • Kok, T.C.1    Van Der Gaast, A.2    Dees, J.3
  • 41
    • 4143121436 scopus 로고    scopus 로고
    • Treatment of metastatic esophagus and gastric cancer
    • Shah M. A., Schwartz G. K., Treatment of metastatic esophagus and gastric cancer Seminars in Oncology 2004 31 4 574 587
    • (2004) Seminars in Oncology , vol.31 , Issue.4 , pp. 574-587
    • Shah, M.A.1    Schwartz, G.K.2
  • 42
    • 0031022803 scopus 로고    scopus 로고
    • Randomized trial comparing epirubicin, cisplatin, and fluorouracil versus fluorouracil, doxorubicin, and methotrexate in advanced esophagogastric cancer
    • Webb A., Cunningham D., Scarffe J. H., Randomized trial comparing epirubicin, cisplatin, and fluorouracil versus fluorouracil, doxorubicin, and methotrexate in advanced esophagogastric cancer Journal of Clinical Oncology 1997 15 1 261 267
    • (1997) Journal of Clinical Oncology , vol.15 , Issue.1 , pp. 261-267
    • Webb, A.1    Cunningham, D.2    Scarffe, J.H.3
  • 43
    • 33750949065 scopus 로고    scopus 로고
    • Phase III study of docetaxel and cisplatin plus fluorouracil compared with cisplatin and fluorouracil as first-line therapy for advanced gastric cancer: A report of the V25 Study Group
    • van Cutsem E., Moiseyenko V. M., Tjulandin S., Phase III study of docetaxel and cisplatin plus fluorouracil compared with cisplatin and fluorouracil as first-line therapy for advanced gastric cancer: a report of the V25 Study Group Journal of Clinical Oncology 2006 24 31 4991 4997
    • (2006) Journal of Clinical Oncology , vol.24 , Issue.31 , pp. 4991-4997
    • Van Cutsem, E.1    Moiseyenko, V.M.2    Tjulandin, S.3
  • 44
    • 52049087904 scopus 로고    scopus 로고
    • Optimizing docetaxel chemotherapy in patients with cancer of the gastric and gastroesophageal junction: Evolution of the docetaxel, cisplatin, and 5-fluorouracil regimen
    • Ajani J. A., Optimizing docetaxel chemotherapy in patients with cancer of the gastric and gastroesophageal junction: evolution of the docetaxel, cisplatin, and 5-fluorouracil regimen Cancer 2008 113 5 945 955
    • (2008) Cancer , vol.113 , Issue.5 , pp. 945-955
    • Ajani, J.A.1
  • 45
  • 46
    • 52449106480 scopus 로고    scopus 로고
    • Irinotecan combined with 5-fluorouracil and leucovorin as second-line chemotherapy for metastatic or relapsed gastric cancer
    • Seo M.-D., Lee K.-W., Lim J. H., Irinotecan combined with 5-fluorouracil and leucovorin as second-line chemotherapy for metastatic or relapsed gastric cancer Japanese Journal of Clinical Oncology 2008 38 9 589 595
    • (2008) Japanese Journal of Clinical Oncology , vol.38 , Issue.9 , pp. 589-595
    • Seo, M.-D.1    Lee, K.-W.2    Lim, J.H.3
  • 47
    • 34247326603 scopus 로고    scopus 로고
    • A phase II study of oxaliplatin with low dose leucovorin and bolus and continuous infusion 5-fluorouracil (modified FOLFOX-4) as first line therapy for patients with advanced gastric cancer
    • Oh S. Y., Kwon H.-C., Seo B.-G., Kim S.-H., Kim J.-S., Kim H.-J., A phase II study of oxaliplatin with low dose leucovorin and bolus and continuous infusion 5-fluorouracil (modified FOLFOX-4) as first line therapy for patients with advanced gastric cancer Acta Oncologica 2007 46 3 336 341
    • (2007) Acta Oncologica , vol.46 , Issue.3 , pp. 336-341
    • Oh, S.Y.1    Kwon, H.-C.2    Seo, B.-G.3    Kim, S.-H.4    Kim, J.-S.5    Kim, H.-J.6
  • 48
    • 33644833992 scopus 로고    scopus 로고
    • Multicenter phase II trial of S-1 plus cisplatin in patients with untreated advanced gastric or gastroesophageal junction adenocarcinoma
    • Ajani J. A., Lee F.-C., Singh D. A., Multicenter phase II trial of S-1 plus cisplatin in patients with untreated advanced gastric or gastroesophageal junction adenocarcinoma Journal of Clinical Oncology 2006 24 4 663 667
    • (2006) Journal of Clinical Oncology , vol.24 , Issue.4 , pp. 663-667
    • Ajani, J.A.1    Lee, F.-C.2    Singh, D.A.3
  • 49
    • 33646253672 scopus 로고    scopus 로고
    • Akt signaling and cancer: Surviving but not moving on
    • Toker A., Yoeli-Lerner M., Akt signaling and cancer: surviving but not moving on Cancer Research 2006 66 8 3963 3966
    • (2006) Cancer Research , vol.66 , Issue.8 , pp. 3963-3966
    • Toker, A.1    Yoeli-Lerner, M.2
  • 50
    • 34248591612 scopus 로고    scopus 로고
    • Targeting the Raf-MEK-ERK mitogen-activated protein kinase cascade for the treatment of cancer
    • Roberts P. J., Der C. J., Targeting the Raf-MEK-ERK mitogen-activated protein kinase cascade for the treatment of cancer Oncogene 2007 26 22 3291 3310
    • (2007) Oncogene , vol.26 , Issue.22 , pp. 3291-3310
    • Roberts, P.J.1    Der, C.J.2
  • 51
    • 34248563290 scopus 로고    scopus 로고
    • The ERK1/2 mitogen-activated protein kinase pathway as a master regulator of the G1- to S-phase transition
    • Meloche S., Pouyssegur J., The ERK1/2 mitogen-activated protein kinase pathway as a master regulator of the G1- to S-phase transition Oncogene 2007 26 22 3227 3239
    • (2007) Oncogene , vol.26 , Issue.22 , pp. 3227-3239
    • Meloche, S.1    Pouyssegur, J.2
  • 52
    • 7444270714 scopus 로고    scopus 로고
    • Epidermal growth factor receptor regulates aberrant expression of insulin-like growth factor-binding protein 3
    • Takaoka M., Harada H., Andl C. D., Epidermal growth factor receptor regulates aberrant expression of insulin-like growth factor-binding protein 3 Cancer Research 2004 64 21 7711 7723
    • (2004) Cancer Research , vol.64 , Issue.21 , pp. 7711-7723
    • Takaoka, M.1    Harada, H.2    Andl, C.D.3
  • 53
    • 0027294912 scopus 로고
    • Amplification and over-expression of the EGFR and erbB-2 genes in human esophageal adenocarcinomas
    • Al-Kasspooles M., Moore J. H., Orringer M. B., Beer D. G., Amplification and over-expression of the EGFR and erbB-2 genes in human esophageal adenocarcinomas International Journal of Cancer 1993 54 2 213 219
    • (1993) International Journal of Cancer , vol.54 , Issue.2 , pp. 213-219
    • Al-Kasspooles, M.1    Moore, J.H.2    Orringer, M.B.3    Beer, D.G.4
  • 54
    • 53349142277 scopus 로고    scopus 로고
    • Gains and amplifications of c-myc, EGFR, and 20.q13 loci in the no dysplasia-dysplasia-adenocarcinoma sequence of barretts esophagus
    • Rygiel A. M., Milano F., Ten Kate F. J., Gains and amplifications of c-myc, EGFR, and 20.q13 loci in the no dysplasia-dysplasia-adenocarcinoma sequence of barretts esophagus Cancer Epidemiology Biomarkers Prevention 2008 17 6 1380 1385
    • (2008) Cancer Epidemiology Biomarkers Prevention , vol.17 , Issue.6 , pp. 1380-1385
    • Rygiel, A.M.1    Milano, F.2    Ten Kate, F.J.3
  • 55
    • 0142250376 scopus 로고    scopus 로고
    • Gene amplification in esophageal adenocarcinomas and barretts with high-grade dysplasia
    • Miller C. T., Moy J. R., Lin L., Gene amplification in esophageal adenocarcinomas and barretts with high-grade dysplasia Clinical Cancer Research 2003 9 13 4819 4825
    • (2003) Clinical Cancer Research , vol.9 , Issue.13 , pp. 4819-4825
    • Miller, C.T.1    Moy, J.R.2    Lin, L.3
  • 57
    • 42649133793 scopus 로고    scopus 로고
    • EGFR in gastric carcinomas: Prognostic significance of protein overexpression and high gene copy number
    • Kim M. A., Lee H. S., Lee H. E., Jeon Y. K., Yang H. K., Kim W. H., EGFR in gastric carcinomas: prognostic significance of protein overexpression and high gene copy number Histopathology 2008 52 6 738 746
    • (2008) Histopathology , vol.52 , Issue.6 , pp. 738-746
    • Kim, M.A.1    Lee, H.S.2    Lee, H.E.3    Jeon, Y.K.4    Yang, H.K.5    Kim, W.H.6
  • 58
    • 33748987894 scopus 로고    scopus 로고
    • Pharmacodynamic studies of gefitinib in tumor biopsy specimens from patients with advanced gastric carcinoma
    • Rojo F., Tabernero J., Albanell J., Pharmacodynamic studies of gefitinib in tumor biopsy specimens from patients with advanced gastric carcinoma Journal of Clinical Oncology 2006 24 26 4309 4316
    • (2006) Journal of Clinical Oncology , vol.24 , Issue.26 , pp. 4309-4316
    • Rojo, F.1    Tabernero, J.2    Albanell, J.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.