Paternal DNA damage suppresses in vitro proliferation of mouse inner cell mass

Journal of the Turkish German Gynecology Association

Volumn 10, Issue 1, 2009, Pages 6-9

  Adiga, Satish Kumar ^a,c   Toyoshima, Megumi ^b   Shimura, Tsutomu ^b   Takeda, Jun ^b   Uematsu, Norio ^b   Kumar, Pratap ^a   Niwa, Ohtsura ^b  

^a MANIPAL UNIVERSITY   (India)

^b KYOTO UNIVERSITY   (Japan)

^c NONE

Author keywords

DNA damage; Implantation potential; Inner cell mass proliferation

Indexed keywords

ANIMAL CELL; ANIMAL EXPERIMENT; ARTICLE; CELL PROLIFERATION; CONTROLLED STUDY; DNA DAMAGE; EMBRYO; EMBRYO CULTURE; EMBRYO DEVELOPMENT; EMBRYO TRANSFER; FEMALE; FERTILIZATION; FETOPLACENTAL UNIT; GENOMIC INSTABILITY; GESTATION PERIOD; GROWTH RETARDATION; IN VITRO STUDY; INNER CELL MASS; MALE; MICRONUCLEUS; MOUSE; NIDATION; NONHUMAN; PREIMPLANTATION EMBRYO; SEMEN ABNORMALITY;

EID: 68949105363     PISSN: 13090399     EISSN: 13090380     Source Type: Journal    
DOI: None     Document Type: Article

References (22)

1. Goldstein LS, Spindle AI, Pedersen PA. X-ray sensitivity of the pre-implantation mouse embryo in vitro. Radiat Res 1975; 62: 276-287.
2. Twigg JP, Irvine DS, Aitken RJ. Oxidative damage to DNA in human spermatozoa does not preclude pronucleus formation at intra cytoplasmic sperm injection. Hum Reprod 1998; 13: 1864-1871.
3. Ahmadi A, Ng SC. Fertilizing ability of DNA-damaged spermatozoa. J Exp Zool 1999; 284: 696-704.
4. Wyrobek AJ. Methods and concepts in detecting abnormal reproductive outcomes of paternal origin. Reprod Toxicol 1993; 7: 3-16.
5. Meistrich ML. Potential genetic risks of using semen collected during chemotherapy. Hum Reprod 1993; 8: 8-10.
6. Lord BI. Transgenerational susceptibility to leukaemia induction resulting from preconception, paternal irradiation. Int J Radiat Biol 1999; 75: 801-810.
7. Haines GA, Hendry JH, Daniel CP, Morris ID. Germ cell and dose-dependent DNA damage measured by the comet assay in murine spermatozoaa after testicular X-irradiation. Biol Reprod 2002; 67: 854-861.
8. Niwa O. Induced genomic instability in irradiated germ cells and in the offspring; reconciling discrepancies among the human and animal studies. Oncogene 2003; 22: 7078-7086.
9. Clute P, Masui Y. Microtubule dependence of chromosome cycles in Xenopus laevis blastomeres under the influence of a DNA synthesis inhibitor, aphidicolin. Dev Biol 1997; 185: 1-13.
10. Ikegami R, Rivera-Bennetts AK, Brooker DL, Yager TD, Effect of inhibitors of DNA replication on early zebrafish embryos: evidence for coordinate activation of multiple intrinsic cell-cycle checkpoints at the mid-blastula transition. Zygote 1997; 5: 153-175.
11. Raff JW, Glover DM. Nuclear and cytoplasmic mitotic cycles continue in Drosophila embryos in which DNA synthesis is inhibited with aphidicolin J Cell Biol 1998; 107, 2009-2019.
12. Lim DS, Hasty P. A mutation in mouse rad51 results in an early embryonic lethal that is suppressed by a mutation in p53. Mol Cell Biol 1996; 16: 7133-7143.
13. Shimura T, Inoue M, Taga M, Shiraishi K, Uematsu N, Takei N, Yuan ZM, Shinohara T, Niwa O. p53-dependent S-phase damage checkpoint and pronuclear cross talk in mouse zygotes with X-irradiated sperm. Mol Cell Biol 2002a; 22: 2220-2228.
14. Shimura T, Toyoshima M, Taga M, Shiraishi K, Uematsu N, Inoue M, Niwa O. The novel surveillance mechanism of the Trp53-dependent s-phase checkpoint ensures chromosome damage repair and preimplantation-stage development of mouse embryos fertilized with x-irradiated sperm. Radiat Res 2002b; 158: 735-742.
15. Toyoshima M, Shimura T, Adiga SK, Taga M, Shiraishi K, Inoue M, Yuan Z-M, Niwa O. Transcription-independent suppression of DNA synthesis by p53 in sperm-irradiated mouse zygotes Oncogene 2005; 24: 3229-3235.
16. Adiga SK, Toyoshima M, Shiraishi K, Shimura T, Takeda J, Taga M, Nagai H, Kumar P, Niwa O. p21 provides stage specific DNA damage control to preimplantation embryos. Oncogene 2007; 13: 26: 6141-9.
17. Newport J, Kirschner M. A major developmental transition in early Xenopus embryos: II. Control of the onset of transcription. Cell 1982; 30: 687-96.
18. Wang QT, Piotrowska K, Ciemerych MA, Milenkovic L, Scott MP, Davis RW, Zernicka-Goetz M. A genome-wide study of gene activity reveals developmental signaling pathways in the preimplantation mouse embryo Dev Cell 2004; 6: 133-44.
19. Hamatani T, Carter MG, Sharov AA, Ko MS. Dynamics of global gene expression changes during mouse preimplantation development. Dev Cell 2004; 6: 117-131.
20. Jeong YJ, Choi HW, Shin HS, Cui XS, Kim NH, Gerton GL, Jun JH. Optimization of real time RT-PCR methods for the analysis of gene expression in mouse eggs and preimplantation embryos. Mol Reprod Dev 2005; 71: 284-289.
21. Heyer BS, MacAuley A, Behrendtsen O, Werb Z. Hypersensitivity to DNA damage leads to increased apoptosis during early mouse development. Genes Dev 2000; 14: 2072-2084.
22. Kamjoo M, Brison DR, Kimber SJ. Apoptosis in the preimplantation mouse embryo: effect of strain difference and in vitro culture. Mol Reprod Dev 2002; 61: 67-77.