The utilization of ultrasound and microbubbles for therapy in acute coronary syndromes

Cardiovascular Research

Volumn 83, Issue 4, 2009, Pages 636-642

  Porter, Thomas R ^a  

^a UNIVERSITY OF NEBRASKA MEDICAL CENTER   (United States)

Author keywords

Microbubbles; Thrombus; Ultrasound

Indexed keywords

ECHISTATIN; ECHO CONTRAST MEDIUM; FIBRINOGEN RECEPTOR; MRX 802; MRX 815; PERFLUTREN; PHOSPHATIDYLSERINE; TISSUE PLASMINOGEN ACTIVATOR; UNCLASSIFIED DRUG;

ACUTE CORONARY SYNDROME; BLOOD CLOT LYSIS; DRUG DELIVERY SYSTEM; DRUG TARGETING; HEART MUSCLE BLOOD FLOW; HUMAN; INTRAVASCULAR ULTRASOUND; MICROBUBBLE; NONHUMAN; PRIORITY JOURNAL; REVIEW; THROMBOSIS; TRANSTHORACIC ECHOCARDIOGRAPHY; ULTRASOUND THERAPY;

ACUTE CORONARY SYNDROME; ANIMALS; CONTRAST MEDIA; HUMANS; MICROBUBBLES; MICROCIRCULATION; MYOCARDIAL INFARCTION; THROMBOLYTIC THERAPY; ULTRASONIC THERAPY;

EID: 68949100634     PISSN: 00086363     EISSN: 17553245     Source Type: Journal    
DOI: 10.1093/cvr/cvp206     Document Type: Review

References (56)

1. Rosamond W, Flegal K, Friday G, Furie K, Go A, Greenlund K et al. Heart disease and stroke statistics - 2007 update: a report from the American Heart Association Statistics Committee and Stroke Statistics Subcommittee. Circulation 2007;115:e69-e171.
2. Waxman S, Mittleman MA, Zarich SW, Fitzpatrick PJ, Lewis SM, Leeman DE et al. Angioscopic assessment of coronary lesions underlying thrombus. Am J Cardiol 1997;79:1106-1109.
3. Ueda Y, Asakura M, Hirayama A, Komamura K, Hori M, Komada K. Intracoronary morphology of culprit lesions after reperfusion in acute myocardial infarction: serial angioscopic observations. J Am Coll Cardiol 1996;27: 606-610.
4. Thieme T, Wernecke KD, Meyer R, Brandenstein E, Habedank D, Hinz A et al. Angioscopic evaluation of atherosclerotic plaques: validation by histomorphologic analysis and association with stable and unstable coronary syndromes. J Am Coll Cardiol 1996;28:1-6.
5. Rentrop KP. Thrombi in acute coronary syndromes: revised and revisited. Circulation 2000;101:1619-1626.
6. Pollack CV Jr, Braunwald E. 2007 Update to the ACC/AHA Guidelines for the Management of Patients With Unstable Angina and Non-ST-Segment Elevation Myocardial Infarction: Implications for Emergency Department Practice. Ann Emerg Med 2008;51:591-606.
7. Nallamothu BK, Bradley EH, Krumholz HM. Time to treatment in primary percutaneous coronary interventions. N Engl J Med 2007;357:1631- 1638.
8. Lundergan CF, Reiner JS, McCarthy WF, Coyne KS, Califf RM, Ross AM. Clinical predictors of early infarct-related artery patency following thrombolytic therapy: importance of body weight, smoking history, infarct-related artery and choice of thrombolytic regimen: the GUSTO-I experience. J Am Coll Cardiol 1998;32:641-647.
9. Ito H, Maruyama A, Iwakura K, Takiuchi S, Masuyama T, Hori M et al. Clinical implications of the 'no reflow' phenomenon. A predictor of complications and left ventricular remodeling in reperfused anterior wall myocardial infarction. Circulation 1996;93:223-228.
10. Khumri TM, Nayyar S, Idupulapati M, Magalski A, Stoner CN, Kusnetzky LL et al. Usefulness of myocardial contrast echocardiography in predicting late mortality in patients with anterior wall acute myocardial infarction. Am J Cardiol 2006;98:1150-1155.
11. Kaul S. Evaluating the 'no reflow' phenomenon with myocardial contrast echocardiography. Basic Res Cardiol 2006;101:391-399.
12. Siegel RJ, Atar S, Fishbein MC, Brasch AV, Peterson TM, Nagai Tet al. Noninvasive, transthoracic, low-frequency ultrasound augments thrombolysis in a canine model of acute myocardial infarction. Circulation 2000;101: 2026-2029.
13. Xie F, Lof J, Matsunaga T, Zutshi R, Porter TR. Diagnostic ultrasound combined with glycoprotein 2b/3a targeted microbubbles improve microvascular recovery following acute coronary thrombotic occlusions. Circulation 2009;119:1358-1360.
14. Wu Y, Unger EC, McCreery TP, Sweitzer RH, Shen D, Wu G. Binding and lysing of blood clots using MRX-408. Invest Radiol 1998;33:880- 885.
15. Schumann PA, Christiansen JP, Quigley RM, McCreery TP, Sweitzer RH, Unger EC et al. Targeted-microbubble binding selectively to GPIIb IIIa receptors of platelet thrombi. Invest Radiol 2002;37:587-593.
16. Alonso A, Della Martina A, Stroick M, Fatar M, Griebe M, Pochon S et al. Molecular imaging of human thrombus with novel abciximab immunobubbles and ultrasound. Stroke 2007;38:1508-1514.
17. Martin MJ, Chung EM, Goodall AH, Della Martina A, Ramnarine KV, Fan L et al. Enhanced detection of thromboemboli with the use of targeted microbubbles. Stroke 2007;38:2726-2732.
18. Trübestein G, Engel C, Stumpff U, Wuttke H, Sobbe A. Embolism by ultrasound-thrombolysis (author's transl). Langenbecks Arch Chir 1976; 340:199-255.
19. Pfaffenberger S, Devcic-Kuhar B, Kastl SP, Huber K, Maurer G, Wojta J et al. Ultrasound thrombolysis. Thromb Haemost 2005;94:26-36.
20. Rosenschein U, Gaul G, Erbel R, Amann F, Velasguez D, Stoerger H et al. Percutaneous transluminal therapy of occluded saphenous vein grafts: can the challenge be met with ultrasound thrombolysis? Circulation 1999;99:26-29.
21. Riggs PN, Francis CW, Bartos SR, Penney DP. Ultrasound enhancement of rabbit femoral artery thrombolysis. Cardiovasc Surg 1997;5:201- 207.
22. Datta S, Coussios C-C, McAdory LE, Tan J, Porter T, De Courten-Myers G et al. Correlation of cavitation with ultrasound enhancement of thrombolysis. Ultrasound Med Biol 2006;32:1257-1267.
23. Porter TR, LeVeen RF, Fox R, Kricsfeld A, Xie F. Thrombolytic enhancement with perfluorocarbon-exposed sonicated dextrose albumin microbubbles. Am Heart J 1996;132:964-968.
24. Everbach EC, Francis CW. Cavitational mechanisms in ultrasound- accelerated thrombolysis at 1 MHz. Ultrasound Med Biol 2000;26:1153-1160.
25. Prokop AF, Soltani A, Roy RA. Cavitational mechanisms in ultrasound-accelerated fibrinolysis. Ultrasound Med Biol 2007;33: 924-933.
26. Holland CK, Apfel RE. Thresholds for transient cavitation produced by pulsed ultrasound in a controlled nuclei environment. J Acoust Soc Am 1990;88:2059-2069.
27. Datta S, Couissios CC, Ammi AY, Mast TD, de Courten-Myers GM, Holland CK. Ultrasound-enhanced thrombolysis using definity as a cavitation nucleation agent. Ultrasound Med Biol 2008;34:1421-1433.
28. Birnbaum Y, Luo H, Nagai T, Fishbein MC, Peterson TM, Li S et al. Noninvasive in vivo clot dissolution without a thrombolytic drug: recanalization of thrombosed iliofemoral arteries by transcutaneous ultrasound combined with intravenous infusion of microbubbles. Circulation 1998;97: 130-134.
29. Nishioka T, Luo H, Fishbein MC, Cercek B, Forrester JS, Kim CJ et al. Dissolution of thrombotic arterial occlusion by high intensity, low frequency ultrasound and dodecafluoropentane emulsion: an in vitro and in vivo study. J Am Coll Cardiol 1997;30:561-568.
30. Culp WC, Porter TR, Xie F, Goertzen TC, McCowan TC, Vonk BN et al. Microbubble potentiated ultrasound as a method of declotting thrombosed dialysis grafts: experimental study in dogs. Cardiovasc Intervent Radiol 2001;24:407-412.
31. Culp WC, Porter TR, McCowan TC, Roberson PK, James CA, Matchett WJ et al. Microbubble-augmented ultrasound declotting of thrombosed arteriovenous dialysis grafts in dogs. J Vasc Interv Radiol 2003;14: 343-347.
32. Tsutsui JM, Xie F, Johanning J, Lof J, Cory B, Thomas L et al. Treatment of deeply located acute intravascular thrombi with low frequency guided ultrasound and intravenous microbubbles. J Ultrasound Med 2006;25: 1161-1168.
33. Culp WC, Porter TR, Lowery J, Xie F, Roberson PK, Marky L. Intracranial clot lysis with intravenous microbubbles and transcranial ultrasound in swine. Stroke 2004;35:2407-2411.
34. Wang B, Wang L, Zhou X-B, Liu Y-M, Wang M, Qin H et al. Thrombolysis effect of a novel targeted microbubble with low-frequency ultrasound in vivo. Thromb Haemost 2008;100:356-361.
35. Shi WT, Power JE, Klibanov AL, Hall CS. P4C-4 In vitro investigation of thrombosis dissolution microbubble-induced continous acoustic activities. IEEE 2007;1985-1988.
36. Nilsson AM, Odselius R, Roijer A, Olsson SB. Pro- and antifibrinolytic effects of ultrasound on streptokinase-induced thrombolysis. Ultrasound Med Biol 1995;21:833-840.
37. Kornowski R, Meltzer RS, Chernine A, Vered Z, Battler A. Does external ultrasound accelerate thrombolysis? Results from a rabbit model. Circulation 1994;89:339-344.
38. Xie F, Lof J, Everbach C, He A, Bennett R, Matsunaga Tet al. Treatment of acute intravascular thrombi with diagnostic ultrasound and intravenous microbubbles. J Am Coll Cardiol Imag 2009;2:511-518.
39. Porter TR, Xie F. Ultrasound, microbubbles, and thrombolysis. Prog Cardiovasc Dis 2001;44:101-110.
40. Siegel RJ, Suchkova VN, Miyamoto T, Luo H, Baggs RB, Neuman Y et al. Ultrasound energy improves myocardial perfusion in the presence of coronary occlusion. J Am Coll Cardiol 2004;44:1454-1458.
41. Miyamoto T, Neuman Y, Luo H, Jeon DS, Kobal S, Ikeno F et al. Coronary vasodilation by noninvasive transcutaneous ultrasound. J Am Coll Cardiol 2003;41:1623-1671.
42. Coggins MP, Sklenar J, Le DE, Wei K, Lindner JR, Kaul S. Noninvasive prediction of ultimate infarct size at the time of acute coronary occlusion based on the extent and magnitude of collateral-derived myocardial blood flow. Circulation 2001;104:2471-2477.
43. Hayat SA, Senior R. Myocardial contrast echocardiography in ST elevation myocardial infarction: ready for prime time. Eur Heart J 2008;29: 299-314.
44. Bolli R, Triana JF, Jeroudi MO. Prolonged impairment of coronary vasodilation after reversible ischemia. Evidence for microvascular 'stunning'. Circ Res 1990;67:332-343.
45. Korosoglou G, Labadze N, Giannitsis E, Bekeredjian R, Hansen A, Hardt SE et al. Usefulness of real-time myocardial perfusion imaging to evaluate tissue level reperfusion in patients with non-ST-elevation myocardial infarction. Am J Cardiol 2005;95:1033-1038.
46. Cohen MG, Tuero E, Bluguermann J, Kevorkian R, Berrocal DH, Carlevaro O et al. Transcutaneous ultrasound-facilitated coronary thrombolysis during acute myocardial infarction. Am J Cardiol 2003;92: 454-457.
47. Slikkerveer J, Dijkmans PA, Sieswerda GT, Doevendans PA, van Dijk AP, Verheugt FW et al. Ultrasound enhanced prehospital thrombolysis using microbubbles infusion in patients with acute ST elevation myocardial infarction: Rationale and design of the Sonolysis study. Trials 2008;9:72.
48. Gibson CM, Schomig A. Coronary and myocardial angiography: angiographic assessment of both epicardial and myocardial perfusion. Circulation 2004;109:3096-3105.
49. Leng Tong K, Kaul S, Xin-Qun W, Rinkevich D, Kalvaitis S, Belcik T et al. Myocardial contrast echocardiography versus thrombolysis in myocardial infarction score in patients presenting to the emergency department with chest pain and a nondiagnostic electrocardiogram. J Am Coll Cardiol 2005;46:920-927.
50. Ay T, Havaux X, Van Camp G, Campanelli B, Gisellu G, Paquet A et al. Destruction of contrast microbubles by ultrasound effects on myocardial function, coronary perfusion pressure, and microvascular integrity. Circulation 2001;104:461-466.
51. Miller DL, Sriscoll EM, Dou C, Armstrong WF, Lucchesi BR. Microvascular permeabilization and cariomyocyte injury provoked by myocardial contrast echocardiography in a canine model. J Am Coll Cardiol 2006;47: 1464-1468.
52. Miller DL, Li P, Dou C, Gordon D, Edwards CA, Armstrong WF. Influence of contrast agent dose and ultrasound exposure on cardiomyocyte injury induced by myocardial contrast echocardiography in rats. Radiology 2005;237:137-143.
53. Vancraeynest D, Kefer J, Hanet C, Fillee C, Beauloye C, Pasquet A et al. Release of cardiac bio-markers during high mechanical index contrast-enhanced echocardiography in humans. Eur Heart J 2007;28: 1236-1241.
54. Miller DL, Li P, Gordon D, Armstrong W. Histological characterization of microlesions induced by myocardial contrast echocardiography. Echocardiography 2005;22:25-34.
55. Tiukinhoy-Laing SD, Huang S, Klegerman M, Holland CK, McPherson DD. Ultrasound-facilitated thrombolysis using tissue-plasminogen activator-loaded echogenic liposomes. Thomb Res 2007;119:777-784.
56. Sakuma T, Sari I, Goodman CN, Lindner JR, Klibanov AL, Kaul S. Simultaneous integrin alphavbeta3 and glycoprotein IIb/IIIa inhibition causes reduction in infarct size in a model of acute coronary thrombosis and primary angioplasty. Cardiovasc Res 2005;66:552-561.