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57749093121
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Inflammation and stem cells in gastrointestinal carcinogenesis
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Quante M., and Wang T.C. Inflammation and stem cells in gastrointestinal carcinogenesis. Physiology 23 (2008) 350-359
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(2008)
Physiology
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Quante, M.1
Wang, T.C.2
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2
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0029149571
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Helicobacter pylori infection and abnormalities of acid secretion in patients with duodenal ulcer disease
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El-Omar E.M., Penman I.D., Ardill J.E., Chittajallu R.S., Howie C., and McColl K.E. Helicobacter pylori infection and abnormalities of acid secretion in patients with duodenal ulcer disease. Gastroenterology 109 (1995) 681-691
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(1995)
Gastroenterology
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El-Omar, E.M.1
Penman, I.D.2
Ardill, J.E.3
Chittajallu, R.S.4
Howie, C.5
McColl, K.E.6
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3
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0030927818
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Helicobacter pylori infection and chronic gastric acid hyposecretion
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El-Omar E.M., Oien K., El Nujumi A., Gillen D., Wirz A., Dahill S., Williams C., Ardill J.E., and McColl K.E. Helicobacter pylori infection and chronic gastric acid hyposecretion. Gastroenterology 113 (1997) 15-24
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(1997)
Gastroenterology
, vol.113
, pp. 15-24
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El-Omar, E.M.1
Oien, K.2
El Nujumi, A.3
Gillen, D.4
Wirz, A.5
Dahill, S.6
Williams, C.7
Ardill, J.E.8
McColl, K.E.9
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4
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0030005551
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The risk of stomach cancer in patients with gastric or duodenal ulcer disease
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Hansson L.E., Nyren O., Hsing A.W., Bergstrom R., Josefsson S., Chow W.H., Fraumeni Jr. J.F., and Adami H.O. The risk of stomach cancer in patients with gastric or duodenal ulcer disease. N Engl J Med 335 (1996) 242-249
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N Engl J Med
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Hansson, L.E.1
Nyren, O.2
Hsing, A.W.3
Bergstrom, R.4
Josefsson, S.5
Chow, W.H.6
Fraumeni Jr., J.F.7
Adami, H.O.8
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5
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0034744083
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The importance of interleukin 1beta in Helicobacter pylori associated disease
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El-Omar E.M. The importance of interleukin 1beta in Helicobacter pylori associated disease. Gut 48 (2001) 743-747
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(2001)
Gut
, vol.48
, pp. 743-747
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El-Omar, E.M.1
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6
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0034704880
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Interleukin-1 polymorphisms associated with increased risk of gastric cancer
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A key paper that was the first to report an association between host genetic factors in the interleukin-1 gene cluster and risk of gastric cancer.
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El-Omar E.M., Carrington M., Chow W.H., McColl K.E., Bream J.H., Young H.A., Herrera J., Lissowska J., Yuan C.C., Rothman N., et al. Interleukin-1 polymorphisms associated with increased risk of gastric cancer. Nature 404 (2000) 398-402. A key paper that was the first to report an association between host genetic factors in the interleukin-1 gene cluster and risk of gastric cancer.
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(2000)
Nature
, vol.404
, pp. 398-402
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El-Omar, E.M.1
Carrington, M.2
Chow, W.H.3
McColl, K.E.4
Bream, J.H.5
Young, H.A.6
Herrera, J.7
Lissowska, J.8
Yuan, C.C.9
Rothman, N.10
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7
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0037622073
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Increased risk of noncardia gastric cancer associated with proinflammatory cytokine gene polymorphisms
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This paper reported for the first time the importance of polymorphisms within pro-inflammatory genes and risk of gastric cancer.
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El-Omar E.M., Rabkin C.S., Gammon M.D., Vaughan T.L., Risch H.A., Schoenberg J.B., Stanford J.L., Mayne S.T., Goedert J., Blot W.J., et al. Increased risk of noncardia gastric cancer associated with proinflammatory cytokine gene polymorphisms. Gastroenterology 124 (2003) 1193-1201. This paper reported for the first time the importance of polymorphisms within pro-inflammatory genes and risk of gastric cancer.
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(2003)
Gastroenterology
, vol.124
, pp. 1193-1201
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El-Omar, E.M.1
Rabkin, C.S.2
Gammon, M.D.3
Vaughan, T.L.4
Risch, H.A.5
Schoenberg, J.B.6
Stanford, J.L.7
Mayne, S.T.8
Goedert, J.9
Blot, W.J.10
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8
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0034793044
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Interleukin 1B and interleukin 1RN polymorphisms are associated with increased risk of gastric carcinoma
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The first paper to independently confirm the role of IL-1 polymorphisms in gastric cancer.
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Machado J.C., Pharoah P., Sousa S., Carvalho R., Oliveira C., Figueiredo C., Amorim A., Seruca R., Caldas C., Carneiro F., and Sobrinho-Simoes M. Interleukin 1B and interleukin 1RN polymorphisms are associated with increased risk of gastric carcinoma. Gastroenterology 121 (2001) 823-829. The first paper to independently confirm the role of IL-1 polymorphisms in gastric cancer.
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(2001)
Gastroenterology
, vol.121
, pp. 823-829
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Machado, J.C.1
Pharoah, P.2
Sousa, S.3
Carvalho, R.4
Oliveira, C.5
Figueiredo, C.6
Amorim, A.7
Seruca, R.8
Caldas, C.9
Carneiro, F.10
Sobrinho-Simoes, M.11
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9
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0037146297
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Helicobacter pylori and interleukin 1 genotyping: an opportunity to identify high-risk individuals for gastric carcinoma
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The first paper to report the importance of host genetic factors combined with H. pylori bacterial virulence factors in increasing the risk of gastric cancer.
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Figueiredo C., Machado J.C., Pharoah P., Seruca R., Sousa S., Carvalho R., Capelinha A.F., Quint W., Caldas C., Van Doorn L.J., et al. Helicobacter pylori and interleukin 1 genotyping: an opportunity to identify high-risk individuals for gastric carcinoma. J Natl Cancer Inst 94 (2002) 1680-1687. The first paper to report the importance of host genetic factors combined with H. pylori bacterial virulence factors in increasing the risk of gastric cancer.
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(2002)
J Natl Cancer Inst
, vol.94
, pp. 1680-1687
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Figueiredo, C.1
Machado, J.C.2
Pharoah, P.3
Seruca, R.4
Sousa, S.5
Carvalho, R.6
Capelinha, A.F.7
Quint, W.8
Caldas, C.9
Van Doorn, L.J.10
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10
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0035984024
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Interleukin 1beta polymorphisms increase risk of hypochlorhydria and atrophic gastritis and reduce risk of duodenal ulcer recurrence in Japan
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Furuta T., El-Omar E.M., Xiao F., Shirai N., Takashima M., and Sugimurra H. Interleukin 1beta polymorphisms increase risk of hypochlorhydria and atrophic gastritis and reduce risk of duodenal ulcer recurrence in Japan. Gastroenterology 123 (2002) 92-105
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(2002)
Gastroenterology
, vol.123
, pp. 92-105
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Furuta, T.1
El-Omar, E.M.2
Xiao, F.3
Shirai, N.4
Takashima, M.5
Sugimurra, H.6
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11
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0345528036
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Association of interleukin 1B gene polymorphism and gastric cancers in high and low prevalence regions in China
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Zeng Z.R., Hu P.J., Hu S., Pang R.P., Chen M.H., Ng M., and Sung J.J.Y. Association of interleukin 1B gene polymorphism and gastric cancers in high and low prevalence regions in China. Gut 52 (2003) 1684-1689
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(2003)
Gut
, vol.52
, pp. 1684-1689
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Zeng, Z.R.1
Hu, P.J.2
Hu, S.3
Pang, R.P.4
Chen, M.H.5
Ng, M.6
Sung, J.J.Y.7
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12
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13244260807
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Role of the polymorphic IL-1B, IL-1RN and TNF-A genes in distal gastric cancer in Mexico
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Garza-Gonzalez E., Bosques-Padilla F.J., El-Omar E., Hold G., Tijerina-Menchaca R., Maldonado-Garza H.J., and Perez-Perez G.I. Role of the polymorphic IL-1B, IL-1RN and TNF-A genes in distal gastric cancer in Mexico. Int J Cancer 114 (2005) 237-241
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(2005)
Int J Cancer
, vol.114
, pp. 237-241
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Garza-Gonzalez, E.1
Bosques-Padilla, F.J.2
El-Omar, E.3
Hold, G.4
Tijerina-Menchaca, R.5
Maldonado-Garza, H.J.6
Perez-Perez, G.I.7
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13
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55649091192
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Helicobacter pylori: host genetics and disease outcomes
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Snaith A., and El-Omar E.M. Helicobacter pylori: host genetics and disease outcomes. Expert Rev Gastroenterol Hepatol 2 (2008) 577-585
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(2008)
Expert Rev Gastroenterol Hepatol
, vol.2
, pp. 577-585
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Snaith, A.1
El-Omar, E.M.2
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14
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33845706436
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Association of interleukin-1 gene polymorphisms with gastric cancer: a meta-analysis
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Wang P., Xia H.H., Zhang J.Y., Dai L.P., Xu X.Q., and Wang K.J. Association of interleukin-1 gene polymorphisms with gastric cancer: a meta-analysis. Int J Cancer 120 (2007) 552-562
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(2007)
Int J Cancer
, vol.120
, pp. 552-562
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Wang, P.1
Xia, H.H.2
Zhang, J.Y.3
Dai, L.P.4
Xu, X.Q.5
Wang, K.J.6
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15
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33749363062
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Interleukin-1beta and interleukin-1 receptor antagonist gene polymorphisms and gastric cancer: a meta-analysis
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Camargo M.C., Mera R., Correa P., Peek Jr. R.M., Fontham E.T., Goodman K.J., Piazuelo M.B., Sicinschi L., Zabaleta J., and Schneider B.G. Interleukin-1beta and interleukin-1 receptor antagonist gene polymorphisms and gastric cancer: a meta-analysis. Cancer Epidemiol Biomark Prev 15 (2006) 1674-1687
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(2006)
Cancer Epidemiol Biomark Prev
, vol.15
, pp. 1674-1687
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Camargo, M.C.1
Mera, R.2
Correa, P.3
Peek Jr., R.M.4
Fontham, E.T.5
Goodman, K.J.6
Piazuelo, M.B.7
Sicinschi, L.8
Zabaleta, J.9
Schneider, B.G.10
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17
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54549089856
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Overexpression of interleukin-1[beta] induces gastric inflammation and cancer and mobilizes myeloid-derived suppressor cells in mice
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A seminal paper showing how overexpression of interleukin-1β in a transgenic mouse model leads to gastric cancer that follows similar stages to the human equivalent disease.
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Tu S., Bhagat G., Cui G., Takaishi S., Kurt-Jones E.A., Rickman B., Betz K.S., Penz-Oesterreicher M., Bjorkdahl O., Fox J.G., and Wang T.C. Overexpression of interleukin-1[beta] induces gastric inflammation and cancer and mobilizes myeloid-derived suppressor cells in mice. Cancer Cell 14 (2008) 408-419. A seminal paper showing how overexpression of interleukin-1β in a transgenic mouse model leads to gastric cancer that follows similar stages to the human equivalent disease.
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(2008)
Cancer Cell
, vol.14
, pp. 408-419
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Tu, S.1
Bhagat, G.2
Cui, G.3
Takaishi, S.4
Kurt-Jones, E.A.5
Rickman, B.6
Betz, K.S.7
Penz-Oesterreicher, M.8
Bjorkdahl, O.9
Fox, J.G.10
Wang, T.C.11
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18
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0042667008
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A proinflammatory genetic profile increases the risk for chronic atrophic gastritis and gastric carcinoma
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Machado J.C., Figueiredo C., Canedo P., Pharoah P., Carvalho R., Nabais S., Castro A.C., Campos M.L., Van Doorn L.J., Caldas C., et al. A proinflammatory genetic profile increases the risk for chronic atrophic gastritis and gastric carcinoma. Gastroenterology 125 (2003) 364-371
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(2003)
Gastroenterology
, vol.125
, pp. 364-371
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Machado, J.C.1
Figueiredo, C.2
Canedo, P.3
Pharoah, P.4
Carvalho, R.5
Nabais, S.6
Castro, A.C.7
Campos, M.L.8
Van Doorn, L.J.9
Caldas, C.10
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19
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20144385230
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Cytokine gene polymorphisms in gastric cancer patients from two Italian areas at high and low cancer prevalence
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Perri F., Piepoli A., Bonvicini C., Gentile A., Quitadamo M., Di Candia M., Cotugno R., Cattaneo F., Zagari M.R., Ricciardiello L., et al. Cytokine gene polymorphisms in gastric cancer patients from two Italian areas at high and low cancer prevalence. Cytokine 30 (2005) 293-302
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(2005)
Cytokine
, vol.30
, pp. 293-302
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Perri, F.1
Piepoli, A.2
Bonvicini, C.3
Gentile, A.4
Quitadamo, M.5
Di Candia, M.6
Cotugno, R.7
Cattaneo, F.8
Zagari, M.R.9
Ricciardiello, L.10
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20
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34247197046
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Novel interleukin-4 and interleukin-1 receptor antagonist gene variations associated with non-cardia gastric cancer in Japan: comprehensive analysis of 207 polymorphisms of 11 cytokine genes
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Seno H., Satoh K., Tsuji S., Shiratsuchi T., Harada Y., Hamajima N., Sugano K., Kawano S., and Chiba T. Novel interleukin-4 and interleukin-1 receptor antagonist gene variations associated with non-cardia gastric cancer in Japan: comprehensive analysis of 207 polymorphisms of 11 cytokine genes. J Gastroenterol Hepatol 22 (2007) 729-737
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(2007)
J Gastroenterol Hepatol
, vol.22
, pp. 729-737
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Seno, H.1
Satoh, K.2
Tsuji, S.3
Shiratsuchi, T.4
Harada, Y.5
Hamajima, N.6
Sugano, K.7
Kawano, S.8
Chiba, T.9
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21
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55249123107
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Interleukin-10-1082 promoter polymorphism associated with gastric cancer among Asians
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Zhou Y., Li N., Zhuang W., Liu G.J., Wu T.X., Yao X., Du L., Wei M.L., and Wu X.T. Interleukin-10-1082 promoter polymorphism associated with gastric cancer among Asians. Eur J Cancer 44 (2008) 2648-2654
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(2008)
Eur J Cancer
, vol.44
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Zhou, Y.1
Li, N.2
Zhuang, W.3
Liu, G.J.4
Wu, T.X.5
Yao, X.6
Du, L.7
Wei, M.L.8
Wu, X.T.9
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22
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59249101028
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Role of bacterial and genetic factors in gastric cancer in Costa Rica
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Con S.A., Takeuchi H., Con-Chin G.R., Con-Chin V.G., Yasuda N., and Con-Wong R. Role of bacterial and genetic factors in gastric cancer in Costa Rica. World J Gastroenterol 15 (2009) 211-218
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(2009)
World J Gastroenterol
, vol.15
, pp. 211-218
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Con, S.A.1
Takeuchi, H.2
Con-Chin, G.R.3
Con-Chin, V.G.4
Yasuda, N.5
Con-Wong, R.6
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23
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0034849755
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Interleukin-8 and human cancer biology
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Xie K. Interleukin-8 and human cancer biology. Cytokine Growth Factor Rev 12 (2001) 375-391
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(2001)
Cytokine Growth Factor Rev
, vol.12
, pp. 375-391
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Xie, K.1
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24
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20044386655
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The polymorphism interleukin 8-251 A/T influences the susceptibility of Helicobacter pylori related gastric diseases in the Japanese population
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Ohyauchi M., Imatani A., Yonechi M., Asano N., Miura A., Iijima K., Koike T., Sekine H., Ohara S., and Shimosegawa T. The polymorphism interleukin 8-251 A/T influences the susceptibility of Helicobacter pylori related gastric diseases in the Japanese population. Gut 54 (2005) 330-335
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(2005)
Gut
, vol.54
, pp. 330-335
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Ohyauchi, M.1
Imatani, A.2
Yonechi, M.3
Asano, N.4
Miura, A.5
Iijima, K.6
Koike, T.7
Sekine, H.8
Ohara, S.9
Shimosegawa, T.10
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25
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16244383220
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Genetic polymorphisms of interleukin (IL)-1B, IL-1RN, IL-8, IL-10 and tumor necrosis factor {alpha} and risk of gastric cancer in a Chinese population
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Lu W., Pan K., Zhang L., Lin D., Miao X., and You W. Genetic polymorphisms of interleukin (IL)-1B, IL-1RN, IL-8, IL-10 and tumor necrosis factor {alpha} and risk of gastric cancer in a Chinese population. Carcinogenesis 26 (2005) 631-636
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(2005)
Carcinogenesis
, vol.26
, pp. 631-636
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Lu, W.1
Pan, K.2
Zhang, L.3
Lin, D.4
Miao, X.5
You, W.6
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26
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28644442435
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Interleukin-8 promoter polymorphism increases the risk of atrophic gastritis and gastric cancer in Japan
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Taguchi A., Ohmiya N., Shirai K., Mabuchi N., Itoh A., Hirooka Y., Niwa Y., and Goto H. Interleukin-8 promoter polymorphism increases the risk of atrophic gastritis and gastric cancer in Japan. Cancer Epidemiol Biomark Prev 14 (2005) 2487-2493
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(2005)
Cancer Epidemiol Biomark Prev
, vol.14
, pp. 2487-2493
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Taguchi, A.1
Ohmiya, N.2
Shirai, K.3
Mabuchi, N.4
Itoh, A.5
Hirooka, Y.6
Niwa, Y.7
Goto, H.8
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27
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44349118502
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The COX-2 promoter polymorphism -765 G > C is associated with early-onset, conventional and stump gastric cancers
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Sitarz R., Leguit R.J., de Leng W.W.J., Polak M., Morsink F.M., Bakker O., Maciejewski R., Offerhaus G.J., and Milne A.N. The COX-2 promoter polymorphism -765 G > C is associated with early-onset, conventional and stump gastric cancers. Mod Pathol 21 (2008) 685-690
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(2008)
Mod Pathol
, vol.21
, pp. 685-690
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Sitarz, R.1
Leguit, R.J.2
de Leng, W.W.J.3
Polak, M.4
Morsink, F.M.5
Bakker, O.6
Maciejewski, R.7
Offerhaus, G.J.8
Milne, A.N.9
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28
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58149215969
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Cyclooxygenase polymorphisms in gastric and colorectal carcinogenesis: are conclusive results available?
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Pereira C., Medeiros R.M., and Nis-Ribeiro M.J. Cyclooxygenase polymorphisms in gastric and colorectal carcinogenesis: are conclusive results available?. Eur J Gastroenterol Hepatol 21 (2009) 76-91
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(2009)
Eur J Gastroenterol Hepatol
, vol.21
, pp. 76-91
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Pereira, C.1
Medeiros, R.M.2
Nis-Ribeiro, M.J.3
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29
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52049101807
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Associations of matrix metalloproteinase-9 protein polymorphisms with lymph node metastasis but not invasion of gastric cancer
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Tang Y., Zhu J., Chen L., Chen L., Zhang S., and Lin J. Associations of matrix metalloproteinase-9 protein polymorphisms with lymph node metastasis but not invasion of gastric cancer. Clin Cancer Res 14 (2008) 2870-2877
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(2008)
Clin Cancer Res
, vol.14
, pp. 2870-2877
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Tang, Y.1
Zhu, J.2
Chen, L.3
Chen, L.4
Zhang, S.5
Lin, J.6
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30
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33947304959
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A functional polymorphism of toll-like receptor 4 gene increases risk of gastric carcinoma and its precursors
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Hold G.L., Rabkin C.S., Chow W.H., Smith M.G., Gammon M.D., Risch H.A., Vaughan T.L., McColl K.E., Lissowska J., Zatonski W., et al. A functional polymorphism of toll-like receptor 4 gene increases risk of gastric carcinoma and its precursors. Gastroenterology 132 (2007) 905-912
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(2007)
Gastroenterology
, vol.132
, pp. 905-912
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Hold, G.L.1
Rabkin, C.S.2
Chow, W.H.3
Smith, M.G.4
Gammon, M.D.5
Risch, H.A.6
Vaughan, T.L.7
McColl, K.E.8
Lissowska, J.9
Zatonski, W.10
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31
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37349009928
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Host-bacterial interactions in Helicobacter pylori infection
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A good review on H. pylori and its associated diseases and the role of bacterial and host genetic factors in the pathogenesis of these.
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Amieva M.R., and El-Omar E.M. Host-bacterial interactions in Helicobacter pylori infection. Gastroenterology 134 (2008) 306-323. A good review on H. pylori and its associated diseases and the role of bacterial and host genetic factors in the pathogenesis of these.
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(2008)
Gastroenterology
, vol.134
, pp. 306-323
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Amieva, M.R.1
El-Omar, E.M.2
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32
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44349178008
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Genetic variation in PSCA is associated with susceptibility to diffuse-type gastric cancer. Nat Genet 2008, 40:730-740. The first paper to show the value of genome wide association studies in gastric cancer.
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Genetic variation in PSCA is associated with susceptibility to diffuse-type gastric cancer. Nat Genet 2008, 40:730-740. The first paper to show the value of genome wide association studies in gastric cancer.
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