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Volumn 2, Issue 4, 2008, Pages 577-585

Helicobacter pylori: Host genetics and disease outcomes

Author keywords

Cytokine; Gastric cancer; Gastritis; Helicobacter pylori; Host genetics; Peptic ulcer disease; Polymorphism

Indexed keywords

BACTERIAL DNA; CYTOKINE; INTERLEUKIN 1; INTERLEUKIN 10; INTERLEUKIN 1BETA; TOLL LIKE RECEPTOR 4;

EID: 55649091192     PISSN: 17474124     EISSN: None     Source Type: Journal    
DOI: 10.1586/17474124.2.4.577     Document Type: Review
Times cited : (44)

References (67)
  • 1
    • 0021259505 scopus 로고
    • Unidentified curved bacilli in the stomach of patients with gastritis and peptic ulceration
    • Marshall BJ, Warren JR. Unidentified curved bacilli in the stomach of patients with gastritis and peptic ulceration. Lancet 1, 1311-1315 (1984).
    • (1984) Lancet , vol.1 , pp. 1311-1315
    • Marshall, B.J.1    Warren, J.R.2
  • 2
    • 55649099787 scopus 로고    scopus 로고
    • IARC monographs on the evaluation of carcinogenic risks to humans, 61. Schistosomes, liver flukes and Helicobacter pylori. IARC, Lyon, France, 177-240 (1994).
    • IARC monographs on the evaluation of carcinogenic risks to humans, Vol. 61. Schistosomes, liver flukes and Helicobacter pylori. IARC, Lyon, France, 177-240 (1994).
  • 3
    • 0037117141 scopus 로고    scopus 로고
    • Age at acquisition of Helicobacter pylori infection: A follow-up study from infancy to adulthood
    • Malaty HM, El-Kasabany A, Graham DY et al. Age at acquisition of Helicobacter pylori infection: a follow-up study from infancy to adulthood. Lancet 359, 931-935 (2002).
    • (2002) Lancet , vol.359 , pp. 931-935
    • Malaty, H.M.1    El-Kasabany, A.2    Graham, D.Y.3
  • 4
    • 0033572955 scopus 로고    scopus 로고
    • Fecal and oral shedding of Helicobacter pylori from healthy infected adults
    • Parsonnet J, Shmuely H, Haggerty T. Fecal and oral shedding of Helicobacter pylori from healthy infected adults. JAMA 282, 2240-2245 (1999).
    • (1999) JAMA , vol.282 , pp. 2240-2245
    • Parsonnet, J.1    Shmuely, H.2    Haggerty, T.3
  • 5
    • 0026395988 scopus 로고
    • The epidemiology of Helicobacter pylori infection
    • Taylor DN, Blaser MJ. The epidemiology of Helicobacter pylori infection. Epidemiol. Rev. 13, 42-59 (1991).
    • (1991) Epidemiol. Rev , vol.13 , pp. 42-59
    • Taylor, D.N.1    Blaser, M.J.2
  • 6
    • 0031003196 scopus 로고    scopus 로고
    • Disappearance of Helicobacter without antibiotics in 12 patients with gastritis
    • Freeman HJ. Disappearance of Helicobacter without antibiotics in 12 patients with gastritis. Can. J. Gastroenterol. 11, 167-172 (1997).
    • (1997) Can. J. Gastroenterol , vol.11 , pp. 167-172
    • Freeman, H.J.1
  • 7
    • 0030878629 scopus 로고    scopus 로고
    • Long-term semi-quantitative follow-up of Helicobacter pylori associated gastritis
    • Tham TC, Sloan JM, Collins JS. Long-term semi-quantitative follow-up of Helicobacter pylori associated gastritis. Ir. J. Med. Sci. 166, 132-134 (1997)
    • (1997) Ir. J. Med. Sci , vol.166 , pp. 132-134
    • Tham, T.C.1    Sloan, J.M.2    Collins, J.S.3
  • 8
    • 37349009928 scopus 로고    scopus 로고
    • Host-bacterial interactions in Helicobacter pylori infection
    • Amieva MR, El-Omar EM. Host-bacterial interactions in Helicobacter pylori infection. Gastroenterology 134, 306-323 (2008).
    • (2008) Gastroenterology , vol.134 , pp. 306-323
    • Amieva, M.R.1    El-Omar, E.M.2
  • 9
    • 4344718486 scopus 로고    scopus 로고
    • Challenge model for Helicobacter pylori infection in human volunteers
    • Graham DY, Opekun AR, Osato MS et al. Challenge model for Helicobacter pylori infection in human volunteers. Gut 53, 1235-1243 (2004).
    • (2004) Gut , vol.53 , pp. 1235-1243
    • Graham, D.Y.1    Opekun, A.R.2    Osato, M.S.3
  • 10
    • 0028900587 scopus 로고
    • The importance of local acid production in the distribution of Helicobacter felis in the mouse stomach
    • Danon SJ, O'Rourke JL, Moss ND et al. The importance of local acid production in the distribution of Helicobacter felis in the mouse stomach. Gastroenterology 108, 1386-1395 (1995).
    • (1995) Gastroenterology , vol.108 , pp. 1386-1395
    • Danon, S.J.1    O'Rourke, J.L.2    Moss, N.D.3
  • 11
    • 15844369552 scopus 로고    scopus 로고
    • Atrophic gastritis and Helicobacter pylori infection in patients with reflux esophagitis treated with omeprazole or fundoplication
    • Kuipers EJ, Lundell L, Klinkenberg-Knol EC et al. Atrophic gastritis and Helicobacter pylori infection in patients with reflux esophagitis treated with omeprazole or fundoplication. N. Engl. J. Med. 334, 1018-1022 (1996).
    • (1996) N. Engl. J. Med , vol.334 , pp. 1018-1022
    • Kuipers, E.J.1    Lundell, L.2    Klinkenberg-Knol, E.C.3
  • 12
    • 0035462919 scopus 로고    scopus 로고
    • Pathogenesis of Helicobacter pylori-induced gastric inflammation
    • Israel DA, Peek RM. Pathogenesis of Helicobacter pylori-induced gastric inflammation. Aliment Pharmacol. Ther. 15, 1271-1290 (2001).
    • (2001) Aliment Pharmacol. Ther , vol.15 , pp. 1271-1290
    • Israel, D.A.1    Peek, R.M.2
  • 13
    • 0026018806 scopus 로고
    • Interleukin-1 is cytoprotective, antisecretory, stimulates PGE2 synthesis by the stomach, and retards gastric emptying
    • Robert A, Olafsson AS, Lancaster C et al. Interleukin-1 is cytoprotective, antisecretory, stimulates PGE2 synthesis by the stomach, and retards gastric emptying. Life Sci. 48, 123-134 (1991).
    • (1991) Life Sci , vol.48 , pp. 123-134
    • Robert, A.1    Olafsson, A.S.2    Lancaster, C.3
  • 14
    • 0026871789 scopus 로고
    • Cytokine inhibition of gastric acid secretion - a little goes a long way
    • Wolfe MM, Nompleggi DJ. Cytokine inhibition of gastric acid secretion - a little goes a long way. Gastroenterolagy 102, 2177-2178 (1992).
    • (1992) Gastroenterolagy , vol.102 , pp. 2177-2178
    • Wolfe, M.M.1    Nompleggi, D.J.2
  • 15
    • 0031922551 scopus 로고    scopus 로고
    • Interleukin 1 β and tumour necrosis factor a inhibit acid secretion in cultured rabbit parietal cells by multiple pathways
    • Beales IL, Calam J. Interleukin 1 β and tumour necrosis factor a inhibit acid secretion in cultured rabbit parietal cells by multiple pathways. Gut 42, 227-234 (1998).
    • (1998) Gut , vol.42 , pp. 227-234
    • Beales, I.L.1    Calam, J.2
  • 16
    • 0030927818 scopus 로고    scopus 로고
    • Helicobacter pylori infection and chronic gastric acid hyposecretion
    • El-Omar EM, Oien K, El Nujumi A et al. Helicobacter pylori infection and chronic gastric acid hyposecretion. Gastroenterology 113, 15-24 (1997).
    • (1997) Gastroenterology , vol.113 , pp. 15-24
    • El-Omar, E.M.1    Oien, K.2    El Nujumi, A.3
  • 17
    • 0029149571 scopus 로고
    • Helicobacter pylori infection and abnormalities of acid secretion in patients with duodenal ulcer disease
    • El-Omar EM, Penman ID, Ardill JE et al. Helicobacter pylori infection and abnormalities of acid secretion in patients with duodenal ulcer disease. Gastroenterology 109, 681-691 (1995).
    • (1995) Gastroenterology , vol.109 , pp. 681-691
    • El-Omar, E.M.1    Penman, I.D.2    Ardill, J.E.3
  • 19
    • 0028900587 scopus 로고
    • The importance of local acid production in the distribution of Helicobacter felis in the mouse stomach
    • Danon SJ, O'Rourke JL, Moss ND et al. The importance of local acid production in the distribution of Helicobacter felis in the mouse stomach. Gastroenterology 108, 1386-1395 (1995).
    • (1995) Gastroenterology , vol.108 , pp. 1386-1395
    • Danon, S.J.1    O'Rourke, J.L.2    Moss, N.D.3
  • 20
    • 33645006153 scopus 로고    scopus 로고
    • Changes of gastric mucosal architecture during long-term omeprazole therapy: Results of a randomized clinical trial
    • Lundell L, Havu N, Miettinen P et al. Changes of gastric mucosal architecture during long-term omeprazole therapy: results of a randomized clinical trial. Aliment Pharmacol. Ther. 23, 639-647 (2006).
    • (2006) Aliment Pharmacol. Ther , vol.23 , pp. 639-647
    • Lundell, L.1    Havu, N.2    Miettinen, P.3
  • 21
    • 33747770334 scopus 로고    scopus 로고
    • Proton pump inhibitors and gastric neoplasia
    • Kuipers EJ. Proton pump inhibitors and gastric neoplasia. Gut 55, 1217-1221 (2006).
    • (2006) Gut , vol.55 , pp. 1217-1221
    • Kuipers, E.J.1
  • 23
    • 0028243163 scopus 로고
    • Helicobacter pylori infection: Genetic and environmental influences. A study of twins
    • Malaty HM, Engstrand L, Pedersen NL et al. Helicobacter pylori infection: genetic and environmental influences. A study of twins. Ann. Intern. Med. 120, 982-986 (1994).
    • (1994) Ann. Intern. Med , vol.120 , pp. 982-986
    • Malaty, H.M.1    Engstrand, L.2    Pedersen, N.L.3
  • 24
    • 33748467625 scopus 로고    scopus 로고
    • Polymorphisms in cytokine genes and risk of Helicobacter pylori infection among Jamaican children
    • Tseng FC, Brown EE, Maiese EM et al. Polymorphisms in cytokine genes and risk of Helicobacter pylori infection among Jamaican children. Helicobacter 11, 425-430 (2006).
    • (2006) Helicobacter , vol.11 , pp. 425-430
    • Tseng, F.C.1    Brown, E.E.2    Maiese, E.M.3
  • 25
    • 33847070741 scopus 로고    scopus 로고
    • IL-1B-511 C-->T polymorphism is associated with increased host susceptibility to Helicobacter pylori infection in Chinese
    • Liou JM, Lin JT, Wang HP et al. IL-1B-511 C-->T polymorphism is associated with increased host susceptibility to Helicobacter pylori infection in Chinese. Helicobacter 12, 142-149 (2007).
    • (2007) Helicobacter , vol.12 , pp. 142-149
    • Liou, J.M.1    Lin, J.T.2    Wang, H.P.3
  • 27
    • 0012218357 scopus 로고    scopus 로고
    • Disease-specific Helicobacter pylori virulence factors: The unfulfilled promise
    • Graham DY, Yamaoka Y. Disease-specific Helicobacter pylori virulence factors: the unfulfilled promise. Helicobacter 5(Suppl. 1), S3-S9 (2000).
    • (2000) Helicobacter , vol.5 , Issue.SUPPL. 1
    • Graham, D.Y.1    Yamaoka, Y.2
  • 28
    • 0029979369 scopus 로고    scopus 로고
    • Biologic basis for interleukin-1 in disease
    • Dinarello CA. Biologic basis for interleukin-1 in disease. Blood 87, 2095-2147 (1996).
    • (1996) Blood , vol.87 , pp. 2095-2147
    • Dinarello, C.A.1
  • 29
    • 0034744083 scopus 로고    scopus 로고
    • The importance of interleukin 1β in Helicobacter pylori associated disease
    • El-Omar EM. The importance of interleukin 1β in Helicobacter pylori associated disease. Gut 48, 743-747 (2001).
    • (2001) Gut , vol.48 , pp. 743-747
    • El-Omar, E.M.1
  • 30
    • 0035319112 scopus 로고    scopus 로고
    • Cytokine gene polymorphism in human disease: On-line databases, supplement 1
    • Bidwell J, Keen L, Gallagher G et al. Cytokine gene polymorphism in human disease: on-line databases, supplement 1. Genes Immun. 2, 61-70 (2001).
    • (2001) Genes Immun , vol.2 , pp. 61-70
    • Bidwell, J.1    Keen, L.2    Gallagher, G.3
  • 31
    • 0034704880 scopus 로고    scopus 로고
    • Interleukin-1 polymorphisms associated with increased risk of gastric cancer
    • El-Omar EM, Carrington M, Chow WH et al. Interleukin-1 polymorphisms associated with increased risk of gastric cancer. Nature 404, 398-402 (2000)
    • (2000) Nature , vol.404 , pp. 398-402
    • El-Omar, E.M.1    Carrington, M.2    Chow, W.H.3
  • 32
    • 0037622073 scopus 로고    scopus 로고
    • Increased risk of noncardia gastric cancer associated with proinflammatory cytokine gene polymorphisms
    • El-Omar EM, Rabkin CS, Gammon MD et al. Increased risk of noncardia gastric cancer associated with proinflammatory cytokine gene polymorphisms. Gastroenterology 124, 1193-1201 (2003).
    • (2003) Gastroenterology , vol.124 , pp. 1193-1201
    • El-Omar, E.M.1    Rabkin, C.S.2    Gammon, M.D.3
  • 33
    • 0034793044 scopus 로고    scopus 로고
    • Interleukin 1B and interleukin 1RN polymorphisms are associated with increased risk of gastric carcinoma
    • Machado JC, Pharoah P, Sousa S et al. Interleukin 1B and interleukin 1RN polymorphisms are associated with increased risk of gastric carcinoma. Gastroenterology 121, 823-829 (2001).
    • (2001) Gastroenterology , vol.121 , pp. 823-829
    • Machado, J.C.1    Pharoah, P.2    Sousa, S.3
  • 34
    • 0037146297 scopus 로고    scopus 로고
    • Helicobacter pylori and interleukin 1 genotyping: An opportunity to identify high-risk individuals for gastric carcinoma
    • Figueiredo C, Machado JC, Pharoah P et al. Helicobacter pylori and interleukin 1 genotyping: an opportunity to identify high-risk individuals for gastric carcinoma. J. Natl Cancer Inst. 94, 1680-1687 (2002).
    • (2002) J. Natl Cancer Inst , vol.94 , pp. 1680-1687
    • Figueiredo, C.1    Machado, J.C.2    Pharoah, P.3
  • 35
    • 0042667008 scopus 로고    scopus 로고
    • A proinflammatory genetic profile increases the risk for chronic atrophic gastritis and gastric carcinoma
    • Machado JC, Figueiredo C, Canedo P et al. A proinflammatory genetic profile increases the risk for chronic atrophic gastritis and gastric carcinoma. Gastroenterology 125, 364-371 (2003).
    • (2003) Gastroenterology , vol.125 , pp. 364-371
    • Machado, J.C.1    Figueiredo, C.2    Canedo, P.3
  • 36
    • 0042315396 scopus 로고    scopus 로고
    • Synergistic effect of Helicobacter pylori virulence factors and interleukin-1 polymorphisms for the development of severe histological changes in the gastric mucosa
    • Rad R, Prinz C, Neu B et al. Synergistic effect of Helicobacter pylori virulence factors and interleukin-1 polymorphisms for the development of severe histological changes in the gastric mucosa. J. Infect. Dis. 188, 272-281 (2003).
    • (2003) J. Infect. Dis , vol.188 , pp. 272-281
    • Rad, R.1    Prinz, C.2    Neu, B.3
  • 37
    • 27744540489 scopus 로고    scopus 로고
    • Interleukin-1 gene polymorphisms and gastric cancer risk in a high-risk Italian population
    • Palli D, Saieva C, Luzzi I et al. Interleukin-1 gene polymorphisms and gastric cancer risk in a high-risk Italian population. Am. J. Gastroenterol. 100, 1941-1948 (2005).
    • (2005) Am. J. Gastroenterol , vol.100 , pp. 1941-1948
    • Palli, D.1    Saieva, C.2    Luzzi, I.3
  • 38
    • 0035984024 scopus 로고    scopus 로고
    • Interleukin 1β polymorphisms increase risk of hypochlorhydria and atrophic gastritis and reduce risk of duodenal ulcer recurrence in Japan
    • Furuta T, El-Omar EM, Xiao F et al. Interleukin 1β polymorphisms increase risk of hypochlorhydria and atrophic gastritis and reduce risk of duodenal ulcer recurrence in Japan. Gastroenterology 123, 92-105 (2002).
    • (2002) Gastroenterology , vol.123 , pp. 92-105
    • Furuta, T.1    El-Omar, E.M.2    Xiao, F.3
  • 39
    • 0345528036 scopus 로고    scopus 로고
    • Association of interleukin 1B gene polymorphism and gastric cancers in high and low prevalence regions in China
    • Zeng ZR, Hu PJ, Hu Set al. Association of interleukin 1B gene polymorphism and gastric cancers in high and low prevalence regions in China. Gut 52, 1684-1689 (2003).
    • (2003) Gut , vol.52 , pp. 1684-1689
    • Zeng, Z.R.1    Hu, P.J.2    Hu, S.3
  • 40
    • 3042569219 scopus 로고    scopus 로고
    • Novel interleukin 1β polymorphism increased the risk of gastric cancer in a Korean population
    • Lee KA, Ki CS, Kim HJ et al. Novel interleukin 1β polymorphism increased the risk of gastric cancer in a Korean population. J. Gastroenterol. 39, 429-433 (2004).
    • (2004) J. Gastroenterol , vol.39 , pp. 429-433
    • Lee, K.A.1    Ki, C.S.2    Kim, H.J.3
  • 41
    • 20044378835 scopus 로고    scopus 로고
    • Interleukin-1B (IL-1B) polymorphisms and gastric mucosal levels of IL-1β cytokine in Korean patients with gastric cancer
    • Chang YW, Jang JY, Kim N H et al. Interleukin-1B (IL-1B) polymorphisms and gastric mucosal levels of IL-1β cytokine in Korean patients with gastric cancer. Int. J. Cancer 114, 465-471 (2005).
    • (2005) Int. J. Cancer , vol.114 , pp. 465-471
    • Chang, Y.W.1    Jang, J.Y.2    Kim, N.H.3
  • 42
    • 5644262478 scopus 로고    scopus 로고
    • Interleukin-1B gene promoter variants are associated with an increased risk of gastric cancer in a Chinese population
    • Yang J, Hu Z, Xu Y et al. Interleukin-1B gene promoter variants are associated with an increased risk of gastric cancer in a Chinese population. Cancer Lett. 215, 191-198 (2004).
    • (2004) Cancer Lett , vol.215 , pp. 191-198
    • Yang, J.1    Hu, Z.2    Xu, Y.3
  • 43
    • 32144455365 scopus 로고    scopus 로고
    • Single nucleotide polymorphisms in the human interleukin-1B gene affect transcription according to haplotype context
    • Chen HM, Wilkins LM, Aziz N et al. Single nucleotide polymorphisms in the human interleukin-1B gene affect transcription according to haplotype context. Hum. Mol. Genet. 15, 519-529 (2006).
    • (2006) Hum. Mol. Genet , vol.15 , pp. 519-529
    • Chen, H.M.1    Wilkins, L.M.2    Aziz, N.3
  • 44
    • 34447534253 scopus 로고    scopus 로고
    • Interaction of polymorphisms in the Interleukin 1B-31 and general transcription factor 2A1 genes on the susceptibility to gastric cancer
    • Lee KA, Park JH, Sohn TS et al. Interaction of polymorphisms in the Interleukin 1B-31 and general transcription factor 2A1 genes on the susceptibility to gastric cancer. Cytokine 38, 96-100 (2007).
    • (2007) Cytokine , vol.38 , pp. 96-100
    • Lee, K.A.1    Park, J.H.2    Sohn, T.S.3
  • 45
    • 34548057795 scopus 로고    scopus 로고
    • Interleukin 1β genetic polymorphisms interact with polyunsaturated fatty acids to modulate risk of the metabolic syndrome
    • Shen J, Arnett DK, Peacock JM et al. Interleukin 1β genetic polymorphisms interact with polyunsaturated fatty acids to modulate risk of the metabolic syndrome. J. Nutr. 137, 1846-1851 (2007).
    • (2007) J. Nutr , vol.137 , pp. 1846-1851
    • Shen, J.1    Arnett, D.K.2    Peacock, J.M.3
  • 46
    • 33748683198 scopus 로고    scopus 로고
    • Overexpression of human interleukin-1β in transgenic mice results in spontaneous gastric inflammation and carcinogenesis
    • Tu, S, Cui G, Takaishi S et al. Overexpression of human interleukin-1β in transgenic mice results in spontaneous gastric inflammation and carcinogenesis, Gastroenterology 128(4 Suppl. 2), A62 (2005).
    • (2005) Gastroenterology , vol.128 , Issue.4 SUPPL. 2
    • Tu, S.1    Cui, G.2    Takaishi, S.3
  • 47
    • 16244383220 scopus 로고    scopus 로고
    • Genetic polymorphisms of interleukin (IL)-IB, IL-1RN, IL-8, IL-10 and tumor necrosis factor α and risk of gastric cancer in a Chinese population
    • Lu W, Pan K, Zhang L et al. Genetic polymorphisms of interleukin (IL)-IB, IL-1RN, IL-8, IL-10 and tumor necrosis factor α and risk of gastric cancer in a Chinese population. Carcinogenesis 26, 631-636 (2005).
    • (2005) Carcinogenesis , vol.26 , pp. 631-636
    • Lu, W.1    Pan, K.2    Zhang, L.3
  • 48
    • 28644442435 scopus 로고    scopus 로고
    • Interleukin-8 promoter polymorphism increases the risk of atrophic gastritis and gastric cancer in Japan
    • Taguchi A, Ohmiya N, Shirai K et al. Interleukin-8 promoter polymorphism increases the risk of atrophic gastritis and gastric cancer in Japan. Cancer Epidemiol. Biomarkers Prev. 14, 2487-2493 (2005).
    • (2005) Cancer Epidemiol. Biomarkers Prev , vol.14 , pp. 2487-2493
    • Taguchi, A.1    Ohmiya, N.2    Shirai, K.3
  • 49
    • 25144473975 scopus 로고    scopus 로고
    • The -251T allele of the interleukin-8 promoter is associated with increased risk of gastric carcinoma featuring diffuse-type histopathology in Chinese population
    • Lee WP, Tai DI, Lan KH et al. The -251T allele of the interleukin-8 promoter is associated with increased risk of gastric carcinoma featuring diffuse-type histopathology in Chinese population. Clin. Cancer Res. 11, 6431-6441 (2005).
    • (2005) Clin. Cancer Res , vol.11 , pp. 6431-6441
    • Lee, W.P.1    Tai, D.I.2    Lan, K.H.3
  • 50
    • 20044386655 scopus 로고    scopus 로고
    • The polymorphism interleukin 8 -251 A/T influences the susceptibility of Helicobacter pylori related gastric diseases in the Japanese population
    • Ohyauchi M, Imatani A, Yonechi M et al. The polymorphism interleukin 8 -251 A/T influences the susceptibility of Helicobacter pylori related gastric diseases in the Japanese population. Gut 54, 330-335 (2005).
    • (2005) Gut , vol.54 , pp. 330-335
    • Ohyauchi, M.1    Imatani, A.2    Yonechi, M.3
  • 51
    • 0033040247 scopus 로고    scopus 로고
    • Review article: Exploring the link between Helicobacter pylori and gastric cancer
    • Kuipers EJ. Review article: exploring the link between Helicobacter pylori and gastric cancer. Aliment Pharmacol. Ther. 13(Suppl. 1), 3-11 (1999).
    • (1999) Aliment Pharmacol. Ther , vol.13 , Issue.SUPPL. 1 , pp. 3-11
    • Kuipers, E.J.1
  • 52
    • 0030785605 scopus 로고    scopus 로고
    • Induction of host signal transduction pathways by Helicobacter pylori
    • Segal ED, Lange C, Covacci A et al. Induction of host signal transduction pathways by Helicobacter pylori. Proc. Natl Acad. Sci. USA 94, 7595-7599 (1997).
    • (1997) Proc. Natl Acad. Sci. USA , vol.94 , pp. 7595-7599
    • Segal, E.D.1    Lange, C.2    Covacci, A.3
  • 53
    • 0038781687 scopus 로고    scopus 로고
    • Helicobacter pylori activates Toll-like receptor 4 expression in gastrointestinal epithelial cells
    • Su B, Ceponis PJ, Lebel S et al. Helicobacter pylori activates Toll-like receptor 4 expression in gastrointestinal epithelial cells. Infect. Immun. 71, 3496-3502 (2003).
    • (2003) Infect. Immun , vol.71 , pp. 3496-3502
    • Su, B.1    Ceponis, P.J.2    Lebel, S.3
  • 54
    • 20344389060 scopus 로고    scopus 로고
    • Toll-like receptors: Linking innate and adaptive immunity
    • Pasare C, Medzhitov R. Toll-like receptors: linking innate and adaptive immunity. Adv. Exp. Med. Biol. 560, 11-18 (2005).
    • (2005) Adv. Exp. Med. Biol , vol.560 , pp. 11-18
    • Pasare, C.1    Medzhitov, R.2
  • 55
    • 12444341944 scopus 로고    scopus 로고
    • Toll-like receptors in innate immunity
    • Takeda K, Akira S. Toll-like receptors in innate immunity. Int. Immunol. 17, 1-14 (2005).
    • (2005) Int. Immunol , vol.17 , pp. 1-14
    • Takeda, K.1    Akira, S.2
  • 56
    • 0034084438 scopus 로고    scopus 로고
    • TLR4 mutations are associated with endotoxin hyporesponsiveness in humans
    • Arbour NC, Lorenz E, Schutte BC et al. TLR4 mutations are associated with endotoxin hyporesponsiveness in humans. Nat. Genet. 25, 187-191 (2000).
    • (2000) Nat. Genet , vol.25 , pp. 187-191
    • Arbour, N.C.1    Lorenz, E.2    Schutte, B.C.3
  • 57
    • 3042521641 scopus 로고    scopus 로고
    • Deficient host-bacteria interactions in inflammatory bowel disease? The Toll-like receptor (TLR)-4 Asp299gly polymorphism is associated with Crohn's disease and ulcerative colitis
    • Franchimont D, Vermeire S, El Housni H et al. Deficient host-bacteria interactions in inflammatory bowel disease? The Toll-like receptor (TLR)-4 Asp299gly polymorphism is associated with Crohn's disease and ulcerative colitis. Gut 53, 987-992 (2004).
    • (2004) Gut , vol.53 , pp. 987-992
    • Franchimont, D.1    Vermeire, S.2    El Housni, H.3
  • 58
    • 0037071251 scopus 로고    scopus 로고
    • Relevance of mutations in the TLR4 receptor in patients with Gram-negative septic shock
    • Lorenz E, Mira JP, Frees KL et al. Relevance of mutations in the TLR4 receptor in patients with Gram-negative septic shock. Arch. Intern. Med. 162, 1028-1032 (2002).
    • (2002) Arch. Intern. Med , vol.162 , pp. 1028-1032
    • Lorenz, E.1    Mira, J.P.2    Frees, K.L.3
  • 59
    • 0037130195 scopus 로고    scopus 로고
    • Toll-like receptor 4 polymorphisms and atherogenesis
    • Kiechl S, Lorenz E, Reindl M et al. Toll-like receptor 4 polymorphisms and atherogenesis. N. Engl. J. Med. 347, 185-192 (2002).
    • (2002) N. Engl. J. Med , vol.347 , pp. 185-192
    • Kiechl, S.1    Lorenz, E.2    Reindl, M.3
  • 60
    • 0042333419 scopus 로고    scopus 로고
    • Toll-like receptor 4-mediated innate IL-10 activates antigen-specific regulatory T cells and confers resistance to Bordetella pertussis by inhibiting inflammatory pathology
    • Higgins SC, Lavelle EC, McCann C et al. Toll-like receptor 4-mediated innate IL-10 activates antigen-specific regulatory T cells and confers resistance to Bordetella pertussis by inhibiting inflammatory pathology. J. Immunol. 171, 3119-3127 (2003).
    • (2003) J. Immunol , vol.171 , pp. 3119-3127
    • Higgins, S.C.1    Lavelle, E.C.2    McCann, C.3
  • 61
    • 33947304959 scopus 로고    scopus 로고
    • A functional polymorphism of Toll-like receptor 4 gene increases risk of gastric carcinoma and its precursors
    • Hold GL, Rabkin CS, Chow WH et al. A functional polymorphism of Toll-like receptor 4 gene increases risk of gastric carcinoma and its precursors. Gastroenterology 132, 905-912 (2007).
    • (2007) Gastroenterology , vol.132 , pp. 905-912
    • Hold, G.L.1    Rabkin, C.S.2    Chow, W.H.3
  • 62
    • 0034920472 scopus 로고    scopus 로고
    • Double gastric infection with Helicobacter pylori and non-Helicobacter pylori bacteria during acid-suppressive therapy: Increase of pro-inflammatory cytokines and development of atrophic gastritis
    • Sanduleanu S, Jonkers D, De Bruine A et al. Double gastric infection with Helicobacter pylori and non-Helicobacter pylori bacteria during acid-suppressive therapy: increase of pro-inflammatory cytokines and development of atrophic gastritis. Aliment. Pharmacol. Ther. 15, 1163-1175 (2001).
    • (2001) Aliment. Pharmacol. Ther , vol.15 , pp. 1163-1175
    • Sanduleanu, S.1    Jonkers, D.2    De Bruine, A.3
  • 63
    • 0036142330 scopus 로고    scopus 로고
    • Genetic or chemical hypochlorhydria is associated with inflammation that modulates parietal and G-cell populations in mice
    • Zavros Y, Rieder G, Ferguson A et al. Genetic or chemical hypochlorhydria is associated with inflammation that modulates parietal and G-cell populations in mice. Gastroenterology 122, 119-133 (2002).
    • (2002) Gastroenterology , vol.122 , pp. 119-133
    • Zavros, Y.1    Rieder, G.2    Ferguson, A.3
  • 64
    • 33748511445 scopus 로고    scopus 로고
    • Mannose-binding lectin-2 genetic variation and stomach cancer risk
    • Baccarelli A, Hou L, Chen J et al. Mannose-binding lectin-2 genetic variation and stomach cancer risk. Int. J. Cancer 119, 1970-1975 (2006).
    • (2006) Int. J. Cancer , vol.119 , pp. 1970-1975
    • Baccarelli, A.1    Hou, L.2    Chen, J.3
  • 65
    • 34547092701 scopus 로고    scopus 로고
    • Genome-wide association scan identifies a colorectal cancer susceptibility locus on chromosome 8q24
    • Zanke BW, Greenwood CM, Rangrej J et al. Genome-wide association scan identifies a colorectal cancer susceptibility locus on chromosome 8q24. Nat. Genet. 39, 989-994 (2007).
    • (2007) Nat. Genet , vol.39 , pp. 989-994
    • Zanke, B.W.1    Greenwood, C.M.2    Rangrej, J.3
  • 66
    • 34547121725 scopus 로고    scopus 로고
    • A common genetic risk factor for colorectal and prostate cancer
    • Haiman CA, Le Marchand L, Yamamato J et al. A common genetic risk factor for colorectal and prostate cancer. Nat. Genet. 39, 954-956 (2007).
    • (2007) Nat. Genet , vol.39 , pp. 954-956
    • Haiman, C.A.1    Le Marchand, L.2    Yamamato, J.3
  • 67
    • 34547498546 scopus 로고    scopus 로고
    • A genome-wide association scan of tag SNPs identifies a susceptibility variant for colorectal cancer at 8q24.21
    • Tomlinson I, Webb E, Carvajal-Carmona L et al. A genome-wide association scan of tag SNPs identifies a susceptibility variant for colorectal cancer at 8q24.21, Nat. Genet. 39, 984-988 (2007).
    • (2007) Nat. Genet , vol.39 , pp. 984-988
    • Tomlinson, I.1    Webb, E.2    Carvajal-Carmona, L.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.