Heat shock protein induction in fetal mouse brain as a measure of stress after whole of gestation exposure to mobile telephony radiofrequency fields

Pathology

Volumn 41, Issue 3, 2009, Pages 276-279

  Finnie, John W ^a   Chidlow, Glyn ^b   Blumbergs, Peter C ^a   Manavis, Jim ^a   Cai, Zhao ^a  

^a HANSON INSTITUTE   (Australia)

^b INSTITUTE OF MEDICAL AND VETERINARY SCIENCE   (Australia)

Author keywords

Fetal brain; Heat shock proteins; Mobile telephony; Stress response

Indexed keywords

HEAT SHOCK PROTEIN; HEAT SHOCK PROTEIN 25; HEAT SHOCK PROTEIN 32; HEAT SHOCK PROTEIN 70;

ANIMAL EXPERIMENT; ARTICLE; BAGG ALBINO MOUSE; BRAIN REGION; BRAIN STEM; FETUS; IMMUNOHISTOCHEMISTRY; IMMUNOREACTIVITY; MOUSE; NONHUMAN; PREGNANCY; PROTEIN EXPRESSION; RADIOFREQUENCY; STRESS; TELEPHONE; ANIMAL; BIOSYNTHESIS; BRAIN; FEMALE; METABOLISM; MOBILE PHONE; PHYSIOLOGICAL STRESS; PRENATAL EXPOSURE; RADIATION EXPOSURE; RADIOFREQUENCY RADIATION;

ANIMALS; BRAIN; CELLULAR PHONE; FEMALE; FETUS; HEAT-SHOCK PROTEINS; MICE; MICE, INBRED BALB C; PREGNANCY; PRENATAL EXPOSURE DELAYED EFFECTS; RADIO WAVES; STRESS, PHYSIOLOGICAL;

EID: 68849111045     PISSN: 00313025     EISSN: 14653931     Source Type: Journal    
DOI: 10.1080/00313020902756261     Document Type: Article

References (22)

1. Cotgreave IA. Biological stress responses to radiofrequency electromagnetic radiation: are mobile phones really so (heat) shocking? Arch Biochem Biophys 2005; 435: 227-240
2. Greenbaum B. Proceedings of WHO-sponsored symposium on sensitivity of children to EMF exposure. Bioelectromagnetics 2005; 26 (Suppl): S1.
3. Kinney HC, Armstrong DD. Perinatal neuropathology. In: Graham DI, Lantos PL, editors. Greenfield's Neuropathology. 7th ed, London: Arnold, 2002; 519-535
4. Finnie JW, Cai Z, Blumbergs PC, et al. Expression of the immediate early gene, c-fos, in fetal brain after whole of gestation exposure of pregnant mice to global system for mobile communication microwaves. Pathology 2006; 38: 333-335
5. Martinez M, Calvo-Torrent A, Herbert J. Mapping brain response to social stress in rodents with c-fos expression: a review. Stress 2002; 5: 3-13.
6. Armstrong CL, Krueger-Naug AM, Currie RW, et al. Constitutive expression of heat shock protein HSP25 in the central nervous system of the developing and adult mouse. J Comp Neurol 2001; 434: 262-274
7. Kregel KC. Invited review: Heat shock proteins: modifying factors in physiological stress responses and acquired thermotolerance. J Appl Physiol 2002; 92: 2177-2186
8. Yenari MA. Heat shock proteins and neuroprotection. Adv Exp Med Biol 2002; 513: 281-299
9. Hardy P. Gnotobiology and breeding techniques. In: Hedrich HJ, Bullock G, editors. The Laboratory Mouse. Amsterdam: Elsevier, 2004; 427-429
10. Australian Radiation Protection and Nuclear Safety Agency (ARPANSA). Radiation Protection Standard for Maximum Exposure Levels to Radiofrequency Fields - 3kHz to 300 GHz. Melbourne: ARPANSA, 2003; (RPS No. 3).
11. Finnie JW, Blumbergs PC, Manavis J, et al. Effect of global system for mobile communication (GSM)-like radiofrequency fields on vascular permeability in mouse brain. Pathology 2001; 33: 338-340
12. Balzano Q, Chou CK, Cicchetti A, et al. An efficient RF exposure system with precise SAR estimation for in-vivo animal studies at 900 MHz. IEEE Trans Microw Theory Tech 2000; 48: 2040-2049
13. Faraone A, Luengas W, Chebrolu S, et al. Radiofrequency dosimetry for the ferris-wheel mouse exposure system. Radiat Res 2006; 165: 105-112
14. Paxinos G, Ashwell KWS, Tork I. Atlas of the Developing Rat Nervous System. 2nd ed. San Diego: Academic Press, 1994.
15. Loones M-T, Chang Y, Morange M. The distribution of heat shock proteins in the nervous system of the unstressed mouse embryo suggests a role in neuronal and non-neuronal differentiation. Cell Stress Chaperones 2000; 5: 291-305.
16. Ewing JF, Haber SN, Maines MD. Normal and heat-induced patterns of expression of heme oxygenase-1 (HSP32) in rat brain: hyperthermia causes rapid induction of mRNA and protein. J Neurochem 1992; 58: 1140-1149
17. Fritze K, Wiessner C, Kuster N, et al. Effect of global system for mobile communication microwave exposure on the genomic response of the rat brain. Neuroscience 1997; 81: 627-639 (Pubitemid 27402511)
18. Belyaev IY, Koch CB, Terenius O, et al. Exposure of rat brain to 915 MHz GSM microwaves induces changes in gene expression but not double stranded DNA breaks or effects on chromatin conformation. Bioelectromagnetics 2006; 27: 295-306.
19. Paparini A, Rossi P, Gianfranceschi G, et al. No evidence of major transcriptional changes in the brain of mice exposed to 1800 MHz GSM signal. Bioelectromagnetics 2008; 29: 312-323
20. Franklin TB, Kruege-Naug AM, Clarke DB, et al. The role of heat shock proteins Hsp70 and Hsp27 in cellular protection of the central nervous system. Int J Hyperthermia 2005; 21: 379-392
21. Brown IR. Induction of heat shock genes in mammalian brain by hyperthermia and tissue injury. In: Mayer RJ, Brown IR, editors. Heat Shock Proteins in the Nervous System. London: Academic Press, 1994; 31-53.
22. Bechtold DA, Brown IR. Heat shock proteins Hsp27 and Hsp32 localise to synaptic sites in the rat cerebellum following hyperthermia. Mol Brain Res 2000; 75: 309-320