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Volumn 10, Issue 3, 2009, Pages 285-290

An unusual cause of multiple organ dysfunction syndrome in the pediatric intensive care unit: Hemophagocytic lymphohistiocytosis

Author keywords

Children; Hemophagocytic lymphohistiocytosis; Multiple organ dysfunction syndrome; Pediatric intensive care unit; Sepsis

Indexed keywords

CYCLOSPORIN A; DEXAMETHASONE; ETOPOSIDE; FERRITIN; IMMUNOGLOBULIN;

EID: 68849103040     PISSN: 15297535     EISSN: None     Source Type: Journal    
DOI: 10.1097/PCC.0b013e318198868b     Document Type: Article
Times cited : (50)

References (39)
  • 1
    • 0026061971 scopus 로고
    • Incidence in Sweden and clinical features of familial hemophagocytic lymphohistiocytosis
    • Henter JI, Elinder G, Soder O, et al: Incidence in Sweden and clinical features of familial hemophagocytic lymphohistiocytosis. Acta Pediatr Scand 1991; 80:428-435
    • (1991) Acta Pediatr Scand , vol.80 , pp. 428-435
    • Henter, J.I.1    Elinder, G.2    Soder, O.3
  • 2
    • 0031925395 scopus 로고    scopus 로고
    • Familial hemophagocytic lymphohistiocytosis: Primary hemophagocytic lymphohistiocytosis
    • Henter JI, Arico M, Elinder G, et al: Familial hemophagocytic lymphohistiocytosis: Primary hemophagocytic lymphohistiocytosis. Hematol Oncol Clin North Am 1998; 12: 417-433
    • (1998) Hematol Oncol Clin North Am , vol.12 , pp. 417-433
    • Henter, J.I.1    Arico, M.2    Elinder, G.3
  • 3
    • 0025787766 scopus 로고
    • Hypercytokinemia in familial hemophagocytic lymphohistiocytosis
    • Henter JI, Elinder G, Söder O, et al: Hypercytokinemia in familial hemophagocytic lymphohistiocytosis. Blood 1991; 78:2918-2922
    • (1991) Blood , vol.78 , pp. 2918-2922
    • Henter, J.I.1    Elinder, G.2    Söder, O.3
  • 4
    • 0018656157 scopus 로고
    • Virus associated hemophagocytic syndrome: A benign histiocytic proliferation distinct from malignant histiocytosis
    • Risdall RJ, McKenna RW, Nesbit ME, et al: Virus associated hemophagocytic syndrome: A benign histiocytic proliferation distinct from malignant histiocytosis. Cancer 1979; 44:993-1002
    • (1979) Cancer , vol.44 , pp. 993-1002
    • Risdall, R.J.1    McKenna, R.W.2    Nesbit, M.E.3
  • 5
    • 0031926347 scopus 로고    scopus 로고
    • Infection- and malignancy- associated hemophagocytic syndromes. Secondary hemophagocytic lymphohistiocytosis
    • Janka G, Imashuku S, Elinder G, et al: Infection- and malignancy- associated hemophagocytic syndromes. Secondary hemophagocytic lymphohistiocytosis. Hematol Oncol Clin North Am 1998; 12:417-433
    • (1998) Hematol Oncol Clin North Am , vol.12 , pp. 417-433
    • Janka, G.1    Imashuku, S.2    Elinder, G.3
  • 6
    • 0030937079 scopus 로고    scopus 로고
    • HLH-94: A treatment protocol for hemophagocytic lymphohistiocytosis
    • HLH study Group of the Histiocyte Society
    • Henter JI, Arico M, Egeler RM: HLH-94: A treatment protocol for hemophagocytic lymphohistiocytosis. HLH study Group of the Histiocyte Society. Med Pediatr Oncol 1997; 28:342-347
    • (1997) Med Pediatr Oncol , vol.28 , pp. 342-347
    • Henter, J.I.1    Arico, M.2    Egeler, R.M.3
  • 7
    • 34248153181 scopus 로고    scopus 로고
    • Epstein- Barr virus- induced hemophagocytic lymhohistiocytosis and X- linked lymphoproliferative disease: Mimicking of sepsis in the pediatric intensive care unit
    • Mischler M, Fleming MG, Shanley TP, et al: Epstein- Barr virus- induced hemophagocytic lymhohistiocytosis and X- linked lymphoproliferative disease: Mimicking of sepsis in the pediatric intensive care unit. Pediatrics 2007; 119:1212-1218
    • (2007) Pediatrics , vol.119 , pp. 1212-1218
    • Mischler, M.1    Fleming, M.G.2    Shanley, T.P.3
  • 8
    • 33845619137 scopus 로고    scopus 로고
    • For the Histiocyte Society: HLH 2004 Diagnostic and Therapeutic Guidelines for Hemophagocytic Lymphohistiocytosis
    • Henter JI, Horne AC, Arico M, et al; for the Histiocyte Society: HLH 2004: Diagnostic and Therapeutic Guidelines for Hemophagocytic Lymphohistiocytosis. Pediatr Blood Cancer 2007; 48:124-131
    • (2007) Pediatr Blood Cancer , vol.48 , pp. 124-131
    • Henter, J.I.1    Horne, A.C.2    Arico, M.3
  • 9
    • 31744445155 scopus 로고    scopus 로고
    • Hemophagocytic lymhohistiocytosis: Diagnosis, pathophysiology, treatment, and future perspectives
    • Verbsky J, Grossman WJ: Hemophagocytic lymhohistiocytosis: Diagnosis, pathophysiology, treatment, and future perspectives. Ann Med 2006; 38:20-31
    • (2006) Ann Med , vol.38 , pp. 20-31
    • Verbsky, J.1    Grossman, W.J.2
  • 10
    • 33644669225 scopus 로고    scopus 로고
    • Correlation between phenotypic heterogeneity and gene mutational characteristics in familial hemophagocytic lymphohistiocytosis (FHL)
    • Ueda I, Ishii E, Morimoto A, et al: Correlation between phenotypic heterogeneity and gene mutational characteristics in familial Hemophagocytic lymphohistiocytosis (FHL). Pediatr Blood Cancer 2006; 46:482-488
    • (2006) Pediatr Blood Cancer , vol.46 , pp. 482-488
    • Ueda, I.1    Ishii, E.2    Morimoto, A.3
  • 11
    • 0036095443 scopus 로고    scopus 로고
    • Perforin expression in cytotoxic lymphocytes from patients with hemophagocytic lymhohistiocytosis and their family members
    • Kogawa K, Lee SM, Villanueva J, et al: Perforin expression in cytotoxic lymphocytes from patients with hemophagocytic lymhohistiocytosis and their family members. Blood 2002; 99:61-66
    • (2002) Blood , vol.99 , pp. 61-66
    • Kogawa, K.1    Lee, S.M.2    Villanueva, J.3
  • 12
    • 0031926347 scopus 로고    scopus 로고
    • Infection- and malignancy associated hemophagocytic syndromes. Secondary hemophagocytic lymphohistiocytosis
    • Janka G, Imashuku S, Elinder G, et al: Infection- and malignancy associated hemophagocytic syndromes. Secondary hemophagocytic lymphohistiocytosis. Hematol Oncol Clin North Am 1998; 12:435-444
    • (1998) Hematol Oncol Clin North Am , vol.12 , pp. 435-444
    • Janka, G.1    Imashuku, S.2    Elinder, G.3
  • 13
    • 0028948476 scopus 로고
    • Immuno-modulation treatment for childhood virus associated haemophagocytic lymphohistiocytosis
    • Chen RL, Lin KH, Lin DT, et al: Immuno-modulation treatment for childhood virus associated haemophagocytic lymphohistiocytosis. Br J Haematol 1995; 89:282-290
    • (1995) Br J Haematol , vol.89 , pp. 282-290
    • Chen, R.L.1    Lin, K.H.2    Lin, D.T.3
  • 14
    • 84992261246 scopus 로고    scopus 로고
    • Hemophagocytic lymphohistiocytic syndrome: Unrecognized cause of multiple organ failure
    • Nahum EI, Ben-Ari J, Stain J, et al: Hemophagocytic lymphohistiocytic syndrome: Unrecognized cause of multiple organ failure. Pediatr Crit Care Med 2000; 1:51-54
    • (2000) Pediatr Crit Care Med , vol.1 , pp. 51-54
    • Nahum, E.I.1    Ben-Ari, J.2    Stain, J.3
  • 15
    • 0033796938 scopus 로고    scopus 로고
    • Reactive hemophagocytic syndrome presenting as a component of multiple organ dysfunction syndrome
    • Gauvin F, Toledano B, Champagne J, et al: Reactive hemophagocytic syndrome presenting as a component of multiple organ dysfunction syndrome. Crit Care Med 2000; 28: 3341-3345
    • (2000) Crit Care Med , vol.28 , pp. 3341-3345
    • Gauvin, F.1    Toledano, B.2    Champagne, J.3
  • 16
    • 33747774507 scopus 로고    scopus 로고
    • The hemophagocytic syndrome: Titrating continuous hemofiltration to the degree of lactic acidosis
    • DiCarlo J, Lui WYS, Frankel L, et al: The hemophagocytic syndrome: Titrating continuous hemofiltration to the degree of lactic acidosis. Pediatr Hematol Oncol 2006; 23: 599-610
    • (2006) Pediatr Hematol Oncol , vol.23 , pp. 599-610
    • Dicarlo, J.1    Lui, W.Y.S.2    Frankel, L.3
  • 17
    • 0037736671 scopus 로고    scopus 로고
    • Hemophagocytic lymphohistiocytosis masquerading as child abuse: Presentation of three cases and review of central nervous system findings in hemophagocytic lymphohistiocytosis
    • Rooms L, Fitzgerald N, McClain KL: Hemophagocytic lymphohistiocytosis masquerading as child abuse: Presentation of three cases and review of central nervous system findings in hemophagocytic lymphohistiocytosis. Pediatrics 2003; 111:636-640
    • (2003) Pediatrics , vol.111 , pp. 636-640
    • Rooms, L.1    Fitzgerald, N.2    McClain, K.L.3
  • 18
    • 0038783334 scopus 로고    scopus 로고
    • Validation of the paediatric logistic organ dysfunction (PELOD) score: Prospective, observational, multicentre study
    • Leteurtre S, Martinot A, Duhamel A, et al: Validation of the paediatric logistic organ dysfunction (PELOD) score: Prospective, observational, multicentre study. Lancet 2003; 362:192-197
    • (2003) Lancet , vol.362 , pp. 192-197
    • Leteurtre, S.1    Martinot, A.2    Duhamel, A.3
  • 20
    • 0035889455 scopus 로고    scopus 로고
    • The role of infections in primary hemophagocytic lymphohistiocytosis: A case series and review of the literature
    • Sung L, Weitzman S, Petric M, et al: The role of infections in primary hemophagocytic lymphohistiocytosis: A case series and review of the literature. Clin Infect Dis 2001; 33: 1644-1648
    • (2001) Clin Infect Dis , vol.33 , pp. 1644-1648
    • Sung, L.1    Weitzman, S.2    Petric, M.3
  • 21
    • 10744221563 scopus 로고    scopus 로고
    • Primary hemophagocytic lymhohistiocytosis in Turkish children
    • Gurgey A, Gögüçs S, Özyürek E, et al: Primary hemophagocytic lymhohistiocytosis in Turkish children. Pediatr Hematol Oncol 2003; 20:367-371
    • (2003) Pediatr Hematol Oncol , vol.20 , pp. 367-371
    • Gurgey, A.1    Gögüçs, S.2    Özyürek, E.3
  • 22
    • 0029911594 scopus 로고    scopus 로고
    • Epidemiology of sepsis and multiple organ dysfunction syndrome in children
    • Proulx F, Fayon M, Farrel CA, et al: Epidemiology of sepsis and multiple organ dysfunction syndrome in children. Chest 1996; 109:1033-1037
    • (1996) Chest , vol.109 , pp. 1033-1037
    • Proulx, F.1    Fayon, M.2    Farrel, C.A.3
  • 23
    • 0022589336 scopus 로고
    • Outcome of pediatric patients with multiple organ system failure
    • Wilkinson JD, Pollack MM, Ruttimann UE, et al: Outcome of pediatric patients with multiple organ system failure. Crit Care Med 1986; 14:271-274
    • (1986) Crit Care Med , vol.14 , pp. 271-274
    • Wilkinson, J.D.1    Pollack, M.M.2    Ruttimann, U.E.3
  • 24
    • 0023618699 scopus 로고
    • Mortality associated with multiple organ system failure and sepsis in pediatric intensive care unit
    • Wilkinson JD, Pollack MM, Glass NL, et al: Mortality associated with multiple organ system failure and sepsis in pediatric intensive care unit. J Pediatr 1987; 111:324-328
    • (1987) J Pediatr , vol.111 , pp. 324-328
    • Wilkinson, J.D.1    Pollack, M.M.2    Glass, N.L.3
  • 25
    • 0028223811 scopus 로고
    • Timing and predictors of death in pediatric patients with multiple organ system failure
    • Proulx F, Gauthier M, Nadeau D, et al: Timing and predictors of death in pediatric patients with multiple organ system failure. Crit Care Med 1994; 22:1025-1031
    • (1994) Crit Care Med , vol.22 , pp. 1025-1031
    • Proulx, F.1    Gauthier, M.2    Nadeau, D.3
  • 26
    • 0035865529 scopus 로고    scopus 로고
    • Hemophagocytic lymphohistiocytosis due to germline mutations in SH2D1A, the X-linked lymphoproliferative dçssease gene
    • Arico M, Imashuku S, Clementi R, et al: Hemophagocytic lymphohistiocytosis due to germline mutations in SH2D1A, the X-linked lymphoproliferative dçssease gene. Blood 2001; 97:1131-1133
    • (2001) Blood , vol.97 , pp. 1131-1133
    • Arico, M.1    Imashuku, S.2    Clementi, R.3
  • 27
    • 0035990979 scopus 로고    scopus 로고
    • Chediak Higashi syndrome: A clinical and molecular view of a rare lysosomal storage disorder
    • Ward DM, Shiflett SL, Kaplan J: Chediak Higashi syndrome: A clinical and molecular view of a rare lysosomal storage disorder. Curr Mol Med 2002; 2:468-477
    • (2002) Curr Mol Med , vol.2 , pp. 468-477
    • Ward, D.M.1    Shiflett, S.L.2    Kaplan, J.3
  • 28
    • 3442877345 scopus 로고    scopus 로고
    • Griscelli syndrome: Characterization of a new mutation and rescue of cytotoxic activity by retroviral transfer of RAB27Agene
    • Bizario JC, Feldman J, Castro FA, et al: Griscelli syndrome: Characterization of a new mutation and rescue of cytotoxic activity by retroviral transfer of RAB27Agene. J Clin Immunol 2004; 24:397-410
    • (2004) J Clin Immunol , vol.24 , pp. 397-410
    • Bizario, J.C.1    Feldman, J.2    Castro, F.A.3
  • 29
    • 0033057615 scopus 로고    scopus 로고
    • Intermittent hemophagocytic lymphohistiocytosis is a regular feature of lysinuric protein intolerance
    • Duval M, Fenneteau O, Doireau V, et al: Intermittent hemophagocytic lymphohistiocytosis is a regular feature of lysinuric protein intolerance. J Pediatr 1999; 134:236-239
    • (1999) J Pediatr , vol.134 , pp. 236-239
    • Duval, M.1    Fenneteau, O.2    Doireau, V.3
  • 30
    • 0037528195 scopus 로고    scopus 로고
    • Imaging characteristics of hemophagocytic lymphohistiocytosis
    • Fitzgerald NE, McClain KL: Imaging characteristics of hemophagocytic lymphohistiocytosis. Pediatr Radiol 2003; 33:392-401
    • (2003) Pediatr Radiol , vol.33 , pp. 392-401
    • Fitzgerald, N.E.1    McClain, K.L.2
  • 31
    • 0030782433 scopus 로고    scopus 로고
    • Neuropathological findings and neurological symptoms in 23 children with hemophagocytic lymphohistiocytosis
    • Henter JI, Nennesmo I: Neuropathological findings and neurological symptoms in 23 children with hemophagocytic lymphohistiocytosis. Pediatrics 1997; 130:358-365
    • (1997) Pediatrics , vol.130 , pp. 358-365
    • Henter, J.I.1    Nennesmo, I.2
  • 32
    • 0030943203 scopus 로고    scopus 로고
    • Frequency and severity of central nervous system lesions in hemophagocytic lymphohistiocytosis
    • Haddad E, Sulis ML, Jabado N, et al: Frequency and severity of central nervous system lesions in hemophagocytic lymphohistiocytosis. Blood 1997; 89:794-800
    • (1997) Blood , vol.89 , pp. 794-800
    • Haddad, E.1    Sulis, M.L.2    Jabado, N.3
  • 33
    • 0033842038 scopus 로고    scopus 로고
    • CNS involvement of virus-associated hemophagocytic syndrome: MR imaging appearance
    • Forbes KPN, Collie DA, Parker A: CNS involvement of virus-associated hemophagocytic syndrome: MR imaging appearance. AJNR Am J Neuroradiol 2000; 21:1248-1250
    • (2000) AJNR Am J Neuroradiol , vol.21 , pp. 1248-1250
    • Forbes, K.P.N.1    Collie, D.A.2    Parker, A.3
  • 34
    • 3142523259 scopus 로고    scopus 로고
    • Hemophagocytic syndrome: A review of 18 pediatric cases
    • Chen CJ, Huang YC, Jaing TH, et al: Hemophagocytic syndrome: A review of 18 pediatric cases. J Microbiol Immunol Infect 2004; 37:157-163
    • (2004) J Microbiol Immunol Infect , vol.37 , pp. 157-163
    • Chen, C.J.1    Huang, Y.C.2    Jaing, T.H.3
  • 35
    • 0020578818 scopus 로고
    • Familial hemophagocytic lymphohistiocytosis
    • Janka GE: Familial hemophagocytic lymphohistiocytosis. Eur J Pediatr 1983; 140: 221-230
    • (1983) Eur J Pediatr , vol.140 , pp. 221-230
    • Janka, G.E.1
  • 36
    • 20944449435 scopus 로고    scopus 로고
    • Genetic subtypes of familial hemophagocytic lymphohistiocytosis: Correlations with clinical features and cytotoxic T lymphocyte/natural killer call functions
    • Ishii E, Ueda I, Shirakawa R, et al: Genetic subtypes of familial hemophagocytic lymphohistiocytosis: Correlations with clinical features and cytotoxic T lymphocyte/natural killer call functions. Blood 2005; 105: 3442-3448
    • (2005) Blood , vol.105 , pp. 3442-3448
    • Ishii, E.1    Ueda, I.2    Shirakawa, R.3
  • 37
    • 0033559748 scopus 로고    scopus 로고
    • Effective control of Epstein-Barr virus-related Hemophagocytic lymphohistiocytosis with immunochemotherapy
    • Imashuku S, Hibi S, Ohara T, et al: Effective control of Epstein-Barr virus-related Hemophagocytic lymphohistiocytosis with immunochemotherapy. Blood 1999; 93: 1869-1874
    • (1999) Blood , vol.93 , pp. 1869-1874
    • Imashuku, S.1    Hibi, S.2    Ohara, T.3
  • 38
    • 5044223401 scopus 로고    scopus 로고
    • Effective use of the recombinant interleukin 1 receptor antagonist anakinra in therapy resistant systemic onset juvenile rheumatoid arthritis
    • Verbsky JW, White AJ: Effective use of the recombinant interleukin 1 receptor antagonist anakinra in therapy resistant systemic onset juvenile rheumatoid arthritis. J Rheumatol 2004; 31:2071-2075
    • (2004) J Rheumatol , vol.31 , pp. 2071-2075
    • Verbsky, J.W.1    White, A.J.2
  • 39
    • 37549051351 scopus 로고    scopus 로고
    • Etanercept for therapy-resistant macrophage activation syndrome
    • Makay M, Yilmaz S, Türkyilmaz Z, et al: Etanercept for therapy-resistant macrophage activation syndrome. Pediatr Blood Cancer 2008; 50:419-421
    • (2008) Pediatr Blood Cancer , vol.50 , pp. 419-421
    • Makay, M.1    Yilmaz, S.2    Türkyilmaz, Z.3


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