Hemostatic consequences of a non-fresh or reconstituted whole blood small volume cardiopulmonary bypass prime in neonates and infants

Paediatric Anaesthesia

Volumn 19, Issue 9, 2009, Pages 854-861

  Hornykewycz, Stephan ^a   Odegard, Kirsten C ^a   Castro, Robert A ^a   Zurakowski, David ^a   Pigula, Frank ^a   Dinardo, James A ^a  

^a BOSTON CHILDREN S HOSPITAL   (United States)

Author keywords

CPB prime; Fibrinogen; Platelets; Reconstituted whole blood

Indexed keywords

ANTITHROMBIN III; APROTININ; BLOOD CLOTTING FACTOR 10; BLOOD CLOTTING FACTOR 5; BLOOD CLOTTING FACTOR 7; BLOOD CLOTTING FACTOR 9; FIBRINOGEN; HEPARIN; METHYLPREDNISOLONE; PROTAMINE; PROTHROMBIN; TRANEXAMIC ACID;

ANEMIA; ARTICLE; BLEEDING; BLOOD; BLOOD VOLUME; CARDIOPULMONARY BYPASS; CLINICAL ARTICLE; CONTINUOUS INFUSION; CONTROLLED STUDY; CRYOPRECIPITATE; FEMALE; FIBRINOGEN BLOOD LEVEL; HEART SURGERY; HEMATOCRIT; HEMOSTASIS; HUMAN; INFANT; INTERMETHOD COMPARISON; LOADING DRUG DOSE; MALE; MICROVASCULATURE; NEWBORN; NON FRESH WHOLE BLOOD; POSTOPERATIVE HEMORRHAGE; PRIORITY JOURNAL; PROTEIN BLOOD LEVEL; PROTEIN DETERMINATION; RECONSTITUTED WHOLE BLOOD; THROMBOCYTE COUNT; THROMBOCYTE TRANSFUSION;

ALGORITHMS; BLOOD CHEMICAL ANALYSIS; BLOOD LOSS, SURGICAL; BLOOD PRESERVATION; BLOOD TRANSFUSION; BLOOD VOLUME; CARDIOPULMONARY BYPASS; COLLAGEN TYPE VIII; FEMALE; FIBRINOGEN; HEMATOCRIT; HEMOSTASIS, SURGICAL; HEPARIN ANTAGONISTS; HUMANS; INFANT; INFANT, NEWBORN; MALE; MODELS, STATISTICAL; PLATELET COUNT; PROTAMINES; THROMBOCYTOPENIA;

EID: 68849086838     PISSN: 11555645     EISSN: 14609592     Source Type: Journal    
DOI: 10.1111/j.1460-9592.2009.03110.x     Document Type: Article

References (25)

1. Baldini M, Costea N, Dameshek W. The viability of stored human platelets. Blood 1960 16 : 1669 1692.
2. Nilsson L, Hedner U, Nilsson IM et al. Shelf-life of bank blood and stored plasma with special reference to coagulation factors. Transfusion 1983 23 (5 377 381.
3. Kern FH, Morana NJ, Sears JJ et al. Coagulation defects in neonates during cardiopulmonary bypass. Ann Thorac Surg 1992 54 (3 541 546.
4. Mou SS, Giroir BP, Molitor-Kirsch EA et al. Fresh whole blood versus reconstituted blood for pump priming in heart surgery in infants. N Engl J Med 2004 351 (16 1635 1644.
5. Odegard KC, McGowan FX Jr., DiNardo JA et al. Coagulation abnormalities in patients with single-ventricle physiology precede the Fontan procedure. J Thorac Cardiovasc Surg 2002 123 (3 459 465.
6. Odegard KC, McGowan FX Jr., Zurakowski D et al. Coagulation factor abnormalities in patients with single-ventricle physiology immediately prior to the Fontan procedure. Ann Thorac Surg 2002 73 (6 1770 1777.
7. Odegard KC, McGowan FX Jr., Zurakowski D et al. Procoagulant and anticoagulant factor abnormalities following the Fontan procedure: increased factor VIII may predispose to thrombosis. J Thorac Cardiovasc Surg 2003 125 (6 1260 1267.
8. Cabral HJ. Multiple comparisons procedures. Circulation 2008 117 (5 698 701.
9. Fitzmaurice GM, Laird N, Ware JH. Applied Longitudinal Analysis. New York : John Wiley, 2004.
10. Miller BE, Mochizuki T, Levy JH et al. Predicting and treating coagulopathies after cardiopulmonary bypass in children. Anesth Analg 1997 85 (6 1196 1202.
11. Eisses MJ, Chandler WL. Cardiopulmonary bypass parameters and hemostatic response to cardiopulmonary bypass in infants versus children. J Cardiothorac Vasc Anesth 2008 22 (1 53 59.
12. McCall MM, Blackwell MM, Smyre JT et al. Fresh frozen plasma in the pediatric pump prime: a prospective, randomized trial. Ann Thorac Surg 2004 77 (3 983 987.
13. Oliver WC Jr., Beynen FM, Nuttall GA et al. Blood loss in infants and children for open heart operations: albumin 5% versus fresh-frozen plasma in the prime. Ann Thorac Surg 2003 75 (5 1506 1512.
14. Chandler WL. Effects of hemodilution, blood loss, and consumption on hemostatic factor levels during cardiopulmonary bypass. J Cardiothorac Vasc Anesth 2005 19 (4 459 467.
15. Gruenwald CE, McCrindle BW, Crawford-Lean L et al. Reconstituted fresh whole blood improves clinical outcomes compared with stored component blood therapy for neonates undergoing cardiopulmonary bypass for cardiac surgery: a randomized controlled trial. J Thorac Cardiovasc Surg 2008 136 (6 1442 1449.
16. Williams GD, Bratton SL, Riley EC et al. Coagulation tests during cardiopulmonary bypass correlate with blood loss in children undergoing cardiac surgery. J Cardiothorac Vasc Anesth 1999 13 : 398 404.
17. Williams GD, Bratton SL, Ramamoorthy C. Factors associated with blood loss and blood product transfusions: a multivariate analysis in children after open-heart surgery. Anesth Analg 1999 89 : 57 64.
18. Tanaka KA, Taketomi T, Szlam F et al. Improved clot formation by combined administration of activated factor VII (NovoSeven) and fibrinogen (Haemocomplettan P). Anesth Analg 2008 106 (3 732 738, table of contents.
19. Haas T, Fries D, Velik-Salchner C et al. Fibrinogen in craniosynostosis surgery. Anesth Analg 2008 106 (3 725 731.
20. Mittermayr M, Streif W, Haas T et al. Hemostatic changes after crystalloid or colloid fluid administration during major orthopedic surgery: the role of fibrinogen administration. Anesth Analg 2007 105 (4 905 917.
21. Miller BE, Tosone SR, Guzzetta NA et al. Fibrinogen in children undergoing cardiac surgery: is it effective? Anesth Analg 2004 99 (5 1341 1346, table of contents.
22. Nielsen VG, Levy JH. Fibrinogen and bleeding: old molecule - new ideas. Anesth Analg 2007 105 (4 902 903.
23. Nielsen VG, Gurley WQ Jr., Burch TM. The impact of factor XIII on coagulation kinetics and clot strength determined by thrombelastography. Anesth Analg 2004 99 (1 120 123.
24. Chandler WL, Patel MA, Gravelle L et al. Factor XIIIA and clot strength after cardiopulmonary bypass. Blood Coagul Fibrinolysis 2001 12 (2 101 108.
25. Shainoff JR, Estafanous FG, Yared JP et al. Low factor XIIIA levels are associated with increased blood loss after coronary artery bypass grafting. J Thorac Cardiovasc Surg 1994 108 (3 437 445.