Cardiopulmonary Bypass Parameters and Hemostatic Response to Cardiopulmonary Bypass in Infants Versus Children

Journal of Cardiothoracic and Vascular Anesthesia

Volumn 22, Issue 1, 2008, Pages 53-59

  Eisses, Michael J ^a   Chandler, Wayne L ^a  

^a UNIVERSITY OF WASHINGTON SCHOOL OF MEDICINE   (United States)

Author keywords

cardiopulmonary bypass; coagulation; congenital heart disease; fibrinolysis; hemostasis

Indexed keywords

FENTANYL; HEPARIN; ISOFLURANE; PROTAMINE; TISSUE PLASMINOGEN ACTIVATOR;

ADOLESCENT; ARTICLE; BLEEDING; BLOOD CLOTTING; CARDIOPULMONARY BYPASS; CHILD; CLINICAL ARTICLE; CONGESTIVE CARDIOMYOPATHY; CONTROLLED STUDY; FEMALE; FIBRINOLYSIS; HEART SURGERY; HEMOSTASIS; HUMAN; INFANT; MALE; PRIORITY JOURNAL;

ADOLESCENT; AGE FACTORS; BLOOD COAGULATION; BLOOD LOSS, SURGICAL; CARDIOPULMONARY BYPASS; CHILD; CHILD, PRESCHOOL; FEMALE; FIBRIN FIBRINOGEN DEGRADATION PRODUCTS; FIBRINOPEPTIDE A; HUMANS; INFANT; MALE; MONITORING, INTRAOPERATIVE; PLASMINOGEN ACTIVATOR INHIBITOR 1; PLATELET COUNT; THROMBIN; TIME FACTORS; TISSUE PLASMINOGEN ACTIVATOR;

EID: 38749127961     PISSN: 10530770     EISSN: None     Source Type: Journal    
DOI: 10.1053/j.jvca.2007.06.006     Document Type: Article

References (22)

1. Williams G.D., Bratton S.L., Riley E., et al. Association between age and blood loss in children undergoing open heart operations. Ann Thorac Surg 66 (1998) 870-876
2. Aldea G.S., Soltow L.O., Chandler W.L., et al. Limitation of thrombin generation, platelet activation, and inflammation by elimination of cardiotomy suction in patients undergoing coronary artery bypass grafting treated with heparin-bonded circuits. J Thorac Cardiovasc Surg 123 (2002) 742-755
3. Despotis G.J., Avidan M.S., and Hogue Jr. C.W. Mechanisms and attenuation of hemostatic activation during extracorporeal circulation. Ann Thorac Surg 72 (2001) S1821-S1831
4. Aldea G.S., Lilly K., Gaudiani J.M., et al. Heparin-bonded circuits improve clinical outcomes in emergency coronary artery bypass grafting. J Card Surg 12 (1997) 389-397
5. Eisses M.J., Seidel K., Aldea G.S., et al. Reducing hemostatic activation during cardiopulmonary bypass: A combined approach. Anesth Analg 98 (2004) 1208-1216
6. Dietrich W., Schopf K., Spannagl M., et al. Influence of high- and low-dose aprotinin on activation of hemostasis in open heart operations. Ann Thorac Surg 65 (1998) 70-77
7. Ray M.J., and Marsh N.A. Aprotinin reduces blood loss after cardiopulmonary bypass by direct inhibition of plasmin. Thromb Haemost 78 (1997) 1021-1026
8. Andrew M., Vegh P., Johnston M., et al. Maturation of the hemostatic system during childhood. Blood 80 (1992) 1998-2005
9. Miller B.E., Tosone S.R., Guzzetta N.A., et al. Fibrinogen in children undergoing cardiac surgery: Is it effective?. Anesth Analg 99 (2004) 1341-1346
10. Chan A.K., Leaker M., Burrows F., et al. Coagulation and fibrinolytic profile of paediatric patients undergoing cardiopulmonary bypass. Thromb Haemost 77 (1997) 270-277
11. Jaggers J.J., Neal M.C., Smith P.K., et al. Infant cardiopulmonary bypass: A procoagulant state. Ann Thorac Surg 68 (1999) 513-520
12. Kern F., Morana N., Sears J., et al. Coagulation defects in neonates during cardiopulmonary bypass. Ann Thorac Surg 54 (1992) 541-546
13. Turner-Gomes S.O., Mitchell L., Williams W.G., et al. Thrombin regulation in congenital heart disease after cardiopulmonary bypass operations. J Thorac Cardiovasc Surg 107 (1994) 562-568
14. Chandler W.L., Jascur M.L., and Hemderson P.J. Measurement of different forms of tPA in plasma. Clin Chem 46 (2000) 38-46
15. Eisses M.J., Velan T., Aldea G.S., et al. Strategies to reduce hemostatic activation during cardiopulmonary bypass. Thromb Res 117 (2006) 689-703
16. Eisses M.J., Geiduschek J.M., Jonmarker C., et al. Effect of polymer coating (poly 2-methoxyethylacrylate) of the oxygenator on hemostatic markers during cardiopulmonary bypass in children. J Cardiothorac Vasc Anesth 21 (2007) 28-34
17. Chandler W.L., and Velan T. Estimating the rate of thrombin and fibrin generation in vivo during cardiopulmonary bypass. Blood 101 (2003) 4355-4362
18. Philippou H., Adami A., Davidson S.J., et al. Tissue factor is rapidly elevated in plasma collected from the pericardial cavity during cardiopulmonary bypass. Thromb Haemost 84 (2000) 124-128
19. De Somer F., Van Belleghem Y., Caes F., et al. Tissue factor as the main activator of the coagulation system during cardiopulmonary bypass. J Thorac Cardiovasc Surg 123 (2002) 951-958
20. Spiess B., Vocelka C., Cochran R., et al. Heparin coated bypass circuits (Carmeda) suppress the release of tissue plasminogen activator during normothermic coronary artery bypass graft surgery. J Cardiothorac Vasc Anesth 12 (1998) 299-304
21. Raivio P., Kuitunen A., Suojaranta-Ylinen R., et al. Thrombin generation during reperfusion after coronary artery bypass surgery associates with postoperative myocardial damage. J Thromb Haemost 4 (2006) 1523-1529
22. Lacour-Gayet F., Clarke D., and Jacobs J. The Aristotle score for congenital heart surgery. Semin Thorac Cardiovasc Surg Pediatr Card Surg Annu 7 (2004) 185-191