Routes, dynamics, and correlates of cochlear inflammation in terminal and recovering experimental meningitis

Laryngoscope

Volumn 119, Issue 8, 2009, Pages 1560-1570

  Per, Cayé Thomasen ^a,b   Lise, Worsøe ^a   Brandt, Christian Thomas ^b,c,d,f   Miyazaki, Hidemi ^a,e   Østergaard, Christian ^a,c   Niels, Frimodt Møller ^c   Thomsen, Jens ^a,b  

^a GENTOFTE UNIVERSITY HOSPITAL   (Denmark)

^b UNIVERSITY OF COPENHAGEN   (Denmark)

^c STATENS SERUM INSTITUT   (Denmark)

^d Rigshospitalet   (Denmark)

^e JIKEI UNIVERSITY SCHOOL OF MEDICINE   (Japan)

^f HVIDOVRE HOSPITAL   (Denmark)

Author keywords

Cochlea; Correlates; Dynamics; Inflammation; Meningitis

Indexed keywords

CEFTRIAXONE; ROCEPHALIN; UNCLASSIFIED DRUG;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ANTIBIOTIC THERAPY; ARTICLE; BACTERIAL COUNT; BLOOD; CELL INFILTRATION; CEREBROSPINAL FLUID; COCHLEA AQUEDUCT; CONTROLLED STUDY; DISEASE ASSOCIATION; DISEASE COURSE; EXPERIMENTAL MODEL; INFLAMMATION; INNER EAR DISEASE; INOCULATION; LEUKOCYTE COUNT; MALE; MICROSCOPY; NONHUMAN; PATHOGENESIS; PERCEPTION DEAFNESS; PERILYMPH; PNEUMOCOCCAL MENINGITIS; PRIORITY JOURNAL; RAT; SHAM PROCEDURE; STREPTOCOCCUS PNEUMONIAE; TREATMENT INDICATION;

ANIMALS; BIOPSY, NEEDLE; CEFTRIAXONE; CEREBROSPINAL FLUID; COCHLEAR DISEASES; DISEASE MODELS, ANIMAL; IMMUNOHISTOCHEMISTRY; INFLAMMATION; LEUKOCYTE COUNT; MALE; MENINGITIS, PNEUMOCOCCAL; MICROSCOPY, ELECTRON; RANDOM ALLOCATION; RATS; RATS, WISTAR; SENSITIVITY AND SPECIFICITY;

EID: 68849085684     PISSN: 0023852X     EISSN: None     Source Type: Journal    
DOI: 10.1002/lary.20260     Document Type: Article

References (26)

1. Dodge PR, Davis H, Feigin RD, et al. Prospective evaluation of hearing impairment as a sequela of acute bacterial meningitis. N Engl J Med 1984;311:869-874.
2. Rasmussen N, Johnsen NJ, Bohr VA. Otologic sequelae after pneumococcal meningitis: a survey of 164 consecutive cases with a follow-up of 94 survivors. Laryngoscope 1991;101:876-882.
3. Merchant SN, Gopen Q. A human temporal bone study of acute bacterial meningogenic labyrinthitis. Am J Otol 1996;17:375-385.
4. Bhatt S, Halpin C, Hsu W, et al. Hearing loss and pneumo- coccal meningitis: an animal model. Laryngoscope 1991;101:1285-1292.
5. Osborne MP, Comis SD, Tarlow MJ, Stephen J. The cochlear lesion in experimental bacterial meningitis of the rabbit. Int J Exp Pathol 1995;76:317-330.
6. Kesser BW, Hashisaki GT, Spindel JH, Ruth RA, Scheld WM. Time course of hearing loss in an animal model of pneumococcal meningitis. Otolaryngol Head Neck Surg 1999;120:628-637.
7. Klein M, Koedel U, Pfister HW, Kastenbauer S. Morphological correlates of acute and permanent hearing loss during experimental pneumococcal meningitis. Brain Pathol 2003;13:123-132.
8. Rappaport JM, Bhatt SM, Burkard RF, Merchant SN, Nadol JB Jr. Prevention of hearing loss in experimental pneumococcal meningitis by administration of dexameth- asone and ketorolac. J Infect Dis 1999;179:264-268; erraum 753.
9. Kastenbauer S, Klein M, Koedel U, Pfister HW. Reactive nitrogen species contribute to blood-labyrinth barrier disruption in suppurative labyrinthitis complicating experimental pneumococcal meningitis in the rat. Brain Res 2001;904:208-217.
10. Klein M, Koedel U, Pfister HW, Kastenbauer S. Meningitis- associated hearing loss: protection by adjunctive antioxidant therapy. Ann Neurol 2003;54:451-458.
11. Ge NN, Brodie SA, Tinling SP, Brodie HA. The effects of superoxide dismutase in gerbils with bacterial meningitis. Otolaryngol Head Neck Surg 2004;131:563-572.
12. Aminpour S, Tinling SP, Brodie HA. Role of tumor necrosis factor-alpha in sensorineural hearing loss after bacterial meningitis. Otol Neurotol 2005;26:602-609.
13. Brandt CT, Caye-Thomasen P, Lund SP, Worsoe L, Oster- gaard C, Frimodt-Moller N, Espersen F, Thomsen J, Lundgren JD. Hearing loss and cochlear damage in experimental pneumococcal meningitis, with special reference to the role of neutrophil granulocytes. Neurobiol Dis 2006;23:300-311.
14. Brandt CT, Lundgren JD, Lund SP, et al. Attenuation of the bacterial load in blood by pretreatment with granulo- cyte-colony-stimulating factor protects rats from fatal outcome and brain damage during Streptococcus pneumo- niae meningitis. Infect Immun 2004;72:4647-4653.
15. Bhatt S, Lauretano A, Cabellos C, et al. Progression of hearing loss in experimental pneumococcal meningitis: correlation with cerebrospinal fluid cytochemistry. J Infect Dis 1993;167:1675-1683.
16. van de Beek D, de Gans J, Mclntyre P, Prasad K. Cortico- steroids in acute bacterial meningitis. Cochrane Database Syst Rev 2003;3:CD004305.
17. Ostergaard C, O'Reilly T, Brandt C, Frimodt-Moller N, Lundgren JD. Influence of the blood bacterial load on the eningeal inflammatory response in Streptococcus pneu- moniae meningitis. BMC Infect Dis 2006;6:78.
18. Feldman WE, Ginsburg CM, McCracken GH Jr, et al. Relation of concentrations of Haemophilus influenzae type b in cerebrospinal fluid to late sequelae of patients with meningitis. Pediatr 1992;100:209-212.
19. Yeung AH, Tinling SP, Brodie HA. Inhibition of post-menin- gitic cochlear injury with cerebrospinal fluid irrigation. Otolaryngol Head Neck Surg 2006;134:214-224.
20. Palva T, Dammert K. Human cochlear aqueduct. Acta Oto- laryngol 1969: 246 (suppl):1-58.
21. Rask-Andersen H, Stahle J, Wilbrand H. Human cochlear aqueduct and its accessory canals. Ann Otol Rhinol Lar- yngol 1977;86(suppl 42):1-16.
22. Palva T. Cochlear aqueduct in infants. Acta Otolaryngol 1970;70:83-94
23. Blank AL, Davis GL, VanDeWater TR, Ruben RJ. Acute Streptococcus pneumoniae meningogenic labyrinthitis. An animal guinea pig model and literature review. Arch Otolaryngol Head Neck Surg 1994;120:1342-1346.
24. Plontke SK, Biegner T, Kammerer B, Delabar U, Salt AN. Dexamethasone concentration gradients along scala tym- pani after application to the round window membrane. Otol Neurotol 2008;29:401-406.
25. Bird PA, Begg EJ, Zhang M, Keast AT, Murray DP, Balkany TJ. Intratympanic versus intravenous delivery of methyl- prednisolone to cochlear perilymph. Otol Neurotol 2007; 28:1124-1130.
26. Barkdull GC, Vu C, Keithley EM, Harris JP. Cochlear microperfusion: experimental evaluation of a potential new therapy for severe hearing loss caused by inflammation. Otol Neurotol 2005;26:19-26.