메뉴 건너뛰기




Volumn 25, Issue 6, 2009, Pages

Inhibition of MEK sensitizes human breast carcinoma cells to endoplasmic reticulum pathway's apoptosis

Author keywords

Apoptosis; Breast carcinoma; ER stress; GRP78; MEK inhibition

Indexed keywords

GLUCOSE REGULATED PROTEIN 78; MITOGEN ACTIVATED PROTEIN KINASE; MITOGEN ACTIVATED PROTEIN KINASE 1; MITOGEN ACTIVATED PROTEIN KINASE 3; PROPIDIUM IODIDE; TUNICAMYCIN; UO 126;

EID: 68849084842     PISSN: 10011978     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article
Times cited : (3)

References (15)
  • 1
    • 22244446505 scopus 로고    scopus 로고
    • The mammalian unfolded protein response
    • J
    • Schroder M, Kaufman R J. The mammalian unfolded protein response[J]. Annu Rev Biochem, 2005,74:739-789
    • (2005) Annu Rev Biochem , vol.74 , pp. 739-789
    • Schroder, M.1    Kaufman, R.J.2
  • 2
    • 4444232905 scopus 로고    scopus 로고
    • The unfolded protein response - A stress signaling pathway of the endoplasmic reticulum
    • DOI 10.1016/j.jchemneu.2004.02.006, PII S0891061804000304
    • Shen X, Zhang K, Kaufman R J. The unfolded protein response-a stress signaling pathway of the endoplasmic reticulum[J]. J Chem Neuroanat, 2004,28(1-2):79-92. (Pubitemid 39195253)
    • (2004) Journal of Chemical Neuroanatomy , vol.28 , Issue.1-2 , pp. 79-92
    • Shen, X.1    Zhang, K.2    Kaufman, R.J.3
  • 3
    • 2942755868 scopus 로고    scopus 로고
    • Signaling the unfolded protein response from the endoplasmic reticulum
    • DOI 10.1074/jbc.R400008200
    • Zhang K, Kaufman R J. Signaling the unfolded protein response from the endoplasmic reticulum[J]. J Biol Chem, 2004,279(25):25935-25938 (Pubitemid 38798732)
    • (2004) Journal of Biological Chemistry , vol.279 , Issue.25 , pp. 25935-25938
    • Zhang, K.1    Kaufman, R.J.2
  • 4
    • 33748076770 scopus 로고    scopus 로고
    • GRP78 as a novel predictor of responsiveness to chemotherapy in breast cancer
    • DOI 10.1158/0008-5472.CAN-06-1660
    • Lee E, Nichols P, Spicer D, et al. GRP78 as a novel predictor of responsiveness to chemotherapy in breast cancer[J]. Cancer Res, 2006,66(16):7849-7853 (Pubitemid 44299145)
    • (2006) Cancer Research , vol.66 , Issue.16 , pp. 7849-7853
    • Lee, E.1    Nichols, P.2    Spicer, D.3    Groshen, S.4    Yu, M.C.5    Lee, A.S.6
  • 5
    • 0038439258 scopus 로고    scopus 로고
    • Activation of ERK1/2 protects melanoma cells from TRAIL-induced apoptosis by inhibiting Smac/DIABLO release from mitochondria
    • J
    • Zhang X D, Borrow J M, Zhang X Y, et al. Activation of ERK1/2 protects melanoma cells from TRAIL-induced apoptosis by inhibiting Smac/DIABLO release from mitochondria[J]. Oncogene, 2003,22(19):2869-2881
    • (2003) Oncogene , vol.22 , Issue.19 , pp. 2869-2881
    • Zhang, X.D.1    Borrow, J.M.2    Zhang, X.Y.3
  • 6
    • 0346995278 scopus 로고    scopus 로고
    • Mitogen - Activated protein kinase pathway-dependent tumor-specific survival signaling in melanoma cells through inactivation of the proapoptotic protein bad
    • J
    • Eisenmann K M, VanBrocklin M W, Staffend N A, et al. Mitogen - activated protein kinase pathway-dependent tumor-specific survival signaling in melanoma cells through inactivation of the proapoptotic protein bad[J]. Cancer Res, 2003,63(23):8330-8337
    • (2003) Cancer Res , vol.63 , Issue.23 , pp. 8330-8337
    • Eisenmann, K.M.1    Vanbrocklin, M.W.2    Staffend, N.A.3
  • 7
    • 33747878462 scopus 로고    scopus 로고
    • Current Strategies in Overcoming Resistance of Cancer Cells to Apoptosis Melanoma as a Model
    • DOI 10.1016/S0074-7696(06)51004-6, PII S0074769606510046, A Survey of Cell Biology
    • Hersey P, Zhuang L, Zhang X D. Current strategies in overcoming resistance of cancer cells to apoptosis melanoma as a model[J]. Int Rev Cytol, 2006,251:131-158 (Pubitemid 44291415)
    • (2006) International Review of Cytology , vol.251 , pp. 131-158
    • Hersey, P.1    Zhuang, L.2    Zhang, X.D.3
  • 8
    • 27144501505 scopus 로고    scopus 로고
    • ERK1/2 inhibition increases antiestrogen treatment efficacy by interfering with hypoxia-induced downregulation of ERalpha: A combination therapy potentially targeting hypoxic and dormant tumor cells
    • DOI 10.1038/sj.onc.1208830, PII 1208830
    • Kronblad A, Hedenfalk I, Nilsson E, et al. ERK1/2 inhibition increases antiestrogen treatment efficacy by interfering with hypoxia-induced downregulation of ERalpha: a combination therapy potentially targeting hypoxic and dormant tumor cells[J]. Oncogene, 2005,24(45):6835-6841 (Pubitemid 41487042)
    • (2005) Oncogene , vol.24 , Issue.45 , pp. 6835-6841
    • Kronblad, A.1    Hedenfalk, I.2    Nilsson, E.3    Pahlman, S.4    Landberg, G.5
  • 9
    • 18344390450 scopus 로고    scopus 로고
    • The Ras-MAPK signal transduction pathway, cancer and chromatin remodeling
    • DOI 10.1139/o04-121
    • Dunn K L, Espino P S, Drobic B, et al. The Ras-MAPK signal transduction pathway, cancer and chromatin remodeling[J]. Biochem Cell Biol, 2005,83(1):1-14. (Pubitemid 40637962)
    • (2005) Biochemistry and Cell Biology , vol.83 , Issue.1 , pp. 1-14
    • Dunn, K.L.1    Espino, P.S.2    Drobic, B.3    He, S.4    Davie, J.R.5
  • 10
    • 10344253840 scopus 로고    scopus 로고
    • Critical role of endogenous Akt/IAPs and MEK1/ERK pathways in counteracting endoplasmic reticulum stress-induced cell death
    • DOI 10.1074/jbc.M407700200
    • Hu P, Han Z, Couvillon A D, et al. Critical role of endogenous Akt/IAPs and MEK1/ERK pathways in counteracting endoplasmic reticulum stress-induced cell death[J]. J Biol Chem, 2004,279(47):49420-49429 (Pubitemid 39625828)
    • (2004) Journal of Biological Chemistry , vol.279 , Issue.47 , pp. 49420-49429
    • Hu, P.1    Han, Z.2    Couvillon, A.D.3    Exton, J.H.4
  • 11
    • 0035890085 scopus 로고    scopus 로고
    • The expanding role of mitochondria in apoptosis
    • J
    • Wang X. The expanding role of mitochondria in apoptosis[J]. Genes Dev, 2001,15(22):2922-2933
    • (2001) Genes Dev , vol.15 , Issue.22 , pp. 2922-2933
    • Wang, X.1
  • 12
    • 0036206485 scopus 로고    scopus 로고
    • Progressing growth of tumor cell and synthesis of Bip/ GRP78
    • J
    • Jiang Z W, LeBourhis-Xuefen, Hubert Hondermarck. Progressing growth of tumor cell and synthesis of Bip/ GRP78[J]. Chin Pharmacol Bull, 2002,18(1):79-83.
    • (2002) Chin Pharmacol Bull , vol.18 , Issue.1 , pp. 79-83
    • Jiang, Z.W.1    LeBourhis-Xuefen2    Hondermarck, H.3
  • 13
    • 33646171070 scopus 로고    scopus 로고
    • Stress induction of GRP78/BiP and its role in cancer
    • J
    • Li J, Lee A S. Stress induction of GRP78/BiP and its role in cancer[J]. Curr Mol Med, 2006,6(1):45-54.
    • (2006) Curr Mol Med , vol.6 , Issue.1 , pp. 45-54
    • Li, J.1    Lee, A.S.2
  • 14
    • 47349130525 scopus 로고    scopus 로고
    • Armet, a UPR-upregulated protein, inhibits cell proliferation and ER stress-induced cell death
    • J
    • Apostolou A, Shen Y, Liang Y, et al. Armet, a UPR-upregulated protein, inhibits cell proliferation and ER stress-induced cell death[J]. Exp Cell Res, 2008,314:2454-2467
    • (2008) Exp Cell Res , vol.314 , pp. 2454-2467
    • Apostolou, A.1    Shen, Y.2    Liang, Y.3
  • 15
    • 35448958407 scopus 로고    scopus 로고
    • Inhibition of MEK sensitizes human melanoma cells to endoplasmic reticulum stress-induced apoptosis
    • DOI 10.1158/0008-5472.CAN-07-2047
    • Jiang C C, Chen L H, Gillespie S, et al. Inhibition of MEK sensitizes human melanoma cells to endoplasmic reticulum stress-induced apoptosis[J]. Cancer Res, 2007,67(20):9750-9761 (Pubitemid 47621222)
    • (2007) Cancer Research , vol.67 , Issue.20 , pp. 9750-9761
    • Chen, C.J.1    Li, H.C.2    Gillespie, S.3    Yu, F.W.4    Kiejda, K.A.5    Xu, D.Z.6    Hersey, P.7


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.