A review of select recent patents on novel nanocarriers

Recent Patents on Drug Delivery and Formulation

Volumn 3, Issue 2, 2009, Pages 137-142

  Grill, Alexander E ^a   Johnston, Neil W ^a   Sadhukha, Tanmoy ^a   Panyam, Jayanth ^a,b  

^a UNIVERSITY OF MINNESOTA   (United States)

^b UNIVERSITY OF MINNESOTA   (United States)

Author keywords

Flash precipitation; Heparin; Immunomodulation; Nanocarriers; Phage; Rotary evaporator; Sarcosine; Targeting

Indexed keywords

ANTINEOPLASTIC AGENT; IMMUNOMODULATING AGENT; IMMUNOMODULATORY POLYNUCLEOTIDE; INDOCYANINE GREEN; LIPOSOME; MACROGOL; NANOCARRIER; NANOPARTICLE; NATURAL PRODUCT; PACLITAXEL HEPARIN FOLIC ACID CONJUGATE; STREPTOMYCES EXTRACT; UNCLASSIFIED DRUG; VASOACTIVE INTESTINAL POLYPEPTIDE; VEROTOXIN; VEROTOXIN BETA; DRUG; DRUG CARRIER; IMMUNOLOGIC FACTOR; POLYMER;

BACTERIOPHAGE; DOSE RESPONSE; DRUG BIOAVAILABILITY; DRUG CLEARANCE; DRUG DELIVERY SYSTEM; DRUG FORMULATION; DRUG HALF LIFE; DRUG MECHANISM; DRUG PENETRATION; DRUG RELEASE; DRUG RESEARCH; DRUG SCREENING; DRUG STABILITY; ESSENTIAL HYPERTENSION; HEART FAILURE; HEART MUSCLE ISCHEMIA; HUMAN; HYPERTENSION; IMMUNOMODULATION; LIPOSOMAL GENE DELIVERY SYSTEM; NANOFABRICATION; NANOTECHNOLOGY; NEOPLASM; NONHUMAN; PATENT; PH; PRECIPITATION; PRIORITY JOURNAL; PROCESS DEVELOPMENT; REVIEW;

DRUG CARRIERS; DRUG DELIVERY SYSTEMS; IMMUNOLOGIC FACTORS; NANOPARTICLES; PATENTS AS TOPIC; PHARMACEUTICAL PREPARATIONS; POLYMERS;

EID: 68849083363     PISSN: 18722113     EISSN: None     Source Type: Journal    
DOI: 10.2174/187221109788452276     Document Type: Review

References (44)

1. Torchilin VP. Targeted pharmaceutical nanocarriers for cancer therapy and imaging. AAPS J 2007; 9: E128-147.
2. Wang X, Yang L. Chen ZG, Shin DM. Application of nanotechnology in cancer therapy and imaging. CA Cancer J Clin 2008; 58 (2): 97-110.
3. Pegaz B, Debefve E, Ballini JP, Konan-Kouakou YN, van den Bergh H. Effect of nanoparticle size on the extravasation and the photothrombic activity of meso(p-tetracarboxyphenyl)porphyrin. J Photochem Photobiol B 2006; 85(3): 216-222.
4. Romberg B, Hennink WE, Storm G. Sheddable coatings for long-circulating nanoparticles. Pharm Res 2008; 25(1): 55-71.
5. Lukyanov AN, Hartner WC, Torchilin VP. Increased accumulation of PEG-PE micelles in the area of experimental myocardial infarction in rabbits. J Control Release 2004; 94(1): 187-193.
6. Asai T, Shimizu K, Kondo M, et al. Anti-neovascular therapy by liposomal DPP-CNDAC targeted to angiogenic vessels. FEBS Lett 2002; 520(1-3): 167-170.
7. Dagar S, Krishnadas A, Rubinstein I, Blend MJ, Onyuksel H. VIP grafted sterically stabilized liposomes for targeted imaging of breast cancer: in vivo Studies. J Control Release 2003; 91(1-2): 123-133.
8. Nasongkla N, Bey E, Ren J, et al. Multifunctional polymeric micelles as cancer-targeted. MRI-ultrasensitive drug delivery systems. Nano Lett 2006; 6(11): 2427-2430.
9. Boomer JA, Thompson DH. Synthesis of acid-labile diplasmenyl lipids for drug and gene delivery applications. Chem Phys Lipids 1999; 99(2): 145-153.
10. Guo X, Szoka FC. Steric stabilization of fusogenic liposomes by a low-pH sensitive PEG - diortho ester - lipid conjugate. Bioconjug Chem 2001; 12(2): 291-300.
11. Gindy ME, Ji S, Hoye TR, Panagiotopoulos AZ, Prud'homme RK. Preparation of poly(ethylene glycol) protected nanoparticles with variable bioconjugate ligand density. Biomacromolecules 2008; 9(10): 2705-2711.
12. Johnson BK, Prud'Homme RK. Process and apparatuses for preparing nanoparticle compositions with amphiphilic copolymers and their use 2004. J Aerosol Med Spring 2006; 19(1): 21-27. doi:10.1089/ jam.2006.19.21.
13. Liu Y, Tong Z, Prud'homme RK. Stabilized polymeric nanoparticles for controlled and efficient release of bifenthrin. Pest Manag Sci 2008; 64(8): 808-812.
14. Onyuksel, H., Rubinstein, I.: US20016197333 (2001).
15. Frase L, Gaffney FA, Lane LD, et al. Cardiovascular effects of vasoactive intestinal peptide in healthy subjects. Am J Cardiol 1987; 60(16): 1356-1361.
16. Onyuksel H, Sejourne F, Suzuki H, Rubinstein I. Human VIP-alpha: A long-acting, biocompatible and biodegradable peptide nanomedicine for essential hypertension. Peptides 2006; 27(9): 2271-2275.
17. Rubinstein I, Ikezaki H, Onyuksel H. Intratracheal and subcutaneous liposomal VIP normalizes arterial pressure in spontaneously hypertensive hamsters. Int J Pharm 2006; 316(1-2): 144-147.
18. Dagar S, Sekosan M, Lee BS, Rubinstein I, Onyuksel H. VIP receptors as molecular targets of breast cancer: Implications for targeted imaging and drug delivery. J Control Release 2001; 74(1-3): 129-134.
19. Dagar S, Sekosan M, Rubinstein I, Onyuksel H. Detection of VIP receptors in MNU-induced breast cancer in rats: Implications for breast cancer targeting. Breast Cancer Res Treat 2001; 65(1): 49-54.
20. Onyuksel H, Mohanty PS, Rubinstein I. VIP-grafted sterically stabilized phospholipid nanomicellar 17-allylamino-17-demethoxy geldanamycin: A novel targeted nanomedicine for breast cancer. Int J Pharm 2009; 365(1-2): 157-61.
21. Rubinstein I, Soos I, Onyuksel H. Intracellular delivery of VIP-grafted sterically stabilized phospholipid mixed nanomicelles in human breast cancer cells. Chem Biol Interact 2008; 171(2): 190-194.
22. Leamon CP, Low PS. Delivery of macromolecules into living cells: A method that exploits folate receptor endocytosis. Proc Natl Acad Sci USA 1991; 88(13): 5572-5576.
23. Russell-Jones G, McTavish K, McEwan J, Rice J, Nowotnik D. Vitamin-mediated targeting as a potential mechanism to increase drug uptake by tumours. J Inorg Biochem 2004; 98(10): 1625-1633.
24. Petrenko, V.A.: WO2007041206A2 (2007).
25. Petrenko V. Evolution of phage display: From bioactive peptides to bioselective nanomaterials. Expert Opin Drug Deliv 2008; 5(8): 825-836.
26. Jayanna PK, Torchilin VP, Petrenko VA. Liposomes targeted by fusion phage proteins. Nanomedicine 2008 5(1): 83-89.
27. Lefebvre d'Hellencourt C, Diaw L, Guenounou M. Immuno-modulation by cytokine antisense oligonucleotides. Eur Cytokine Netw 1995; 6(1): 7-19.
28. Molavi O, Ma Z, Hamdy S, Lavasanifar A, Samuel J. Immuno-modulatory and anticancer effects of intratumoral co-delivery of synthetic lipid a adjuvant and STAT3 Inhibitor, JSI-124. Immuno-pharmacol Immunotoxicol 2008; 1-14.
29. Van Nest, G., Tuck, S.: WO0168144A2 (2001).
30. Lee ES, Na K, Bae YH. Polymeric micelle for tumor pH and folate-mediated targeting. J Control Release 2003; 91(1-2): 103-113.
31. Bae, Y.H., Na, K., Lee, E.S.: US20050118252A1 (2005).
32. Oh KT, Lee ES, Kim D, Bae YH. L-histidine-based pH-sensitive anticancer drug carrier micelle: Reconstitution and brief evaluation of its systemic toxicity. Int J Pharm 2008; 358(1-2): 177-183.
33. Cho, E.C., Lim, H.J., Shim, J.W., Park, J.Y., Lee, H.-J., Cho, J.C., Kim, J.: WO2007078060A1 (2007).
34. Grela P, Sawa-Makarska J, Gordiyenko Y, Robinson CV, Grankowski N, Tchorzewski M. Structural properties of the human acidic ribosomal P proteins forming the P1-P2 heterocomplex. J Biochem 2008; 143(2): 169-177.
35. Lim H J, Cho EC, Shim J, Kim DH, An EJ, Kim J. Polymer-associated liposomes as a novel delivery system for cyclodextrin-bound drugs. J Colloid Interface Sci 2008; 320(2): 460-468.
36. Baek S, Kim J, Kim D, Lee C, Chung DK. Inhibitory effect of dalbergioidin isolated from the trunk of Lespedeza cyrtobotrya on melanin biosynthesis. J Microbiol Biotechnol 2008; 18(5): 874-879.
37. Hanes, J., Dawson, M.R., Wirtz, D., Fu, J., Krauland, E.M.: US20080166414A1 (2008).
38. Brock TJ, Tingsanchali JH, Rosales AM, Creecy CM, McGinity JW, Peppas NA. Dynamics of Poly(ethylene glycol)-Tethered, pH responsive networks. Polymer (Guildf) 2007; 48(17): 5042-5048.
39. Yoncheva K, Lizarraga E, Irache JM. Pegylated nanoparticles based on poly(methyl vinyl ether-co-maleic anhydride): Preparation and evaluation of their bioadhesive properties. Eur J Pharm Sci 2005; 24(5): 411-419.
40. Lai SK, O'Hanlon DE, Harrold S, et al. Rapid transport of large polymeric nanoparticles in fresh undiluted human mucus. Proc Natl Acad Sci USA 2007; 104(5): 1482-1487.
41. Nie, S., Lee, Y., Kim, G.: WO200642146A2 (2006).
42. Akitsu, H., Ozeki, E., Fushimi, R., Kimura, S., Isozaki, M., Nozawa, S.: US20080019908A1 (2008).
43. Abulrob, A., Zhang, J.: WO2007036022A1 (2007).
44. Abulrob A, Sprong H, Van Bergen en Henegouwen P, Stanimirovic D. The blood-brain barrier transmigrating single domain antibody: Mechanisms of transport and antigenic epitopes in human brain endothelial cells. J Neurochem 2005; 95(4): 1201-1214.