Influence of temporary chondroitinase ABC-induced glycosaminoglycan suppression on maturation of tissue-engineered cartilage

Tissue Engineering - Part A

Volumn 15, Issue 8, 2009, Pages 2065-2072

  Bian, Liming ^a   Crivello, Keith M ^b   Ng, Kenneth W ^a   Xu, Duo ^a   Williams, David Y ^a   Ateshian, Gerard A ^a   Hung, Clark T ^a  

^a Cellular Engineering Laboratory Department of Biomedical Engineering Columbia University ^*  (United States)

^b ST LUKE S ROOSEVELT HOSPITAL CENTER   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

CARTILAGE; COLLAGEN; LIGAMENTS; SYNTHESIS (CHEMICAL);

CARTILAGE TISSUE ENGINEERING; CARTILAGE TISSUES; COLLAGEN CONCENTRATION; COLLAGEN CONTENT; COLLAGEN SYNTHESIS; CULTURE MEDIA; ENZYMATIC TREATMENTS; GLYCOSAMINOGLYCANS; IN-VITRO; PRE-TREATMENT; PROTEOGLYCANS; TIME POINTS; TISSUE ENGINEERED CARTILAGE; TISSUE-ENGINEERED CONSTRUCTS; TRANSPORT PATHWAYS;

TISSUE ENGINEERING;

CHONDROITIN ABC LYASE; GLYCOSAMINOGLYCAN; PROTEOGLYCAN;

ANIMAL CELL; ANIMAL TISSUE; ARTICLE; CALF (BOVINE); CARTILAGE; COLLAGEN SYNTHESIS; CONTROLLED STUDY; CULTURE MEDIUM; IN VITRO STUDY; MONITORING; NONHUMAN; PRIORITY JOURNAL; PROTEIN DEGRADATION; TISSUE ENGINEERING;

ANIMALS; CARTILAGE; CATTLE; CELL DIFFERENTIATION; CHONDROITIN ABC LYASE; GLYCOSAMINOGLYCANS; GLYCOSIDE HYDROLASES; PHENAZINES; STAINING AND LABELING; TENSILE STRENGTH; TIME FACTORS; TISSUE ENGINEERING;

EID: 68749120739     PISSN: 19373341     EISSN: 1937335X     Source Type: Journal    
DOI: 10.1089/ten.tea.2008.0495     Document Type: Article

References (41)

1. Guilak, F., Sah, R.L., and Setton, L.A. Physical regulation of cartilage metabolism. In: Mow, V.C., and Hayes, W.C., eds. Basic Orthopaedic Biomechanics. Philadelphia: Lippincott-Raven, 1997, pp. 179-207.
2. Mow, V.C., Bachrach, N.M., Setton, L.A., and Guilak, F. Stress, strain, pressure, and flow fields in articular cartilage and chondrocytes. In: Mow, V.C., Guilak, F., Hayes, W.C., Tran-Son-Tay, R., and Hochmuth, R.M., eds. Cell Mechanics and Cellular Engineering. New York: Springer-Verlag, 1994, pp. 345-79.
3. Byers, B.A., Mauck, R.L., Chiang, I.E., and Tuan, R.S. Transient exposure to transforming growth factor beta 3 under serum-free conditions enhances the biomechanical and biochemical maturation of tissue-engineered cartilage. Tissue Eng 14, 1821, 2008.
4. Lima, E.G., Bian, L., Ng, K.W., Mauck, R.L., Byers, B.A., Tuan, R.S., Ateshian, G.A., and Hung, C.T. The beneficial effect of delayed compressive loading on tissue-engineered cartilage constructs cultured with TGF-beta3. Osteoarthritis Cartilage/OARS, Osteoarthritis Res Soc 15, 1025, 2007.
5. Asanbaeva, A., Masuda, K., Thonar, E.J., Klisch, S.M., and Sah, R.L. Mechanisms of cartilage growth: modulation of balance between proteoglycan and collagen in vitro using chondroitinase ABC. Arthritis Rheum 56, 188, 2007.
6. Katta, J., Stapleton, T., Ingham, E., Jin, Z.M., and Fisher, J. The effect of glycosaminoglycan depletion on the friction and deformation of articular cartilage. Proc Inst Mech Eng 222, 1, 2008.
7. Otsuki, S., Brinson, D.C., Creighton, L., Kinoshita, M., Sah, R.L., D'Lima, D., and Lotz, M. The effect of glycosaminoglycan loss on chondrocyte viability: a study on porcine cartilage explants. Arthritis Rheum 58, 1076, 2008.
8. Yamagata, T., Saito, H., Habuchi, O., and Suzuki, S. Purification and properties of bacterial chondroitinases and chondrosulfatases. J Biol Chem 243, 1523, 1968.
9. Lyyra, T., Arokoski, J.P., Oksala, N., Vihko, A., Hyttinen, M., Jurvelin, J.S., and Kiviranta, I. Experimental validation of arthroscopic cartilage stiffness measurement using enzy-matically degraded cartilage samples. Phys Med Biol 44, 525, 1999.
10. Nahir, A.M., Shomrat, D., and Awad, M. Chondroitinase ABC affects the activity of intracellular enzymes in rabbit articular cartilage chondrocytes. J Rheumatol 22, 702, 1995.
11. Lotke, P.A., and Granda, J.L. Alterations in the permeability of articular cartilage by proteolytic enzymes. Arthritis Rheum 15, 302, 1972.
12. Bonassar, L.J., Frank, E.H., Murray, J.C., Paguio, C.G., Moore, V.L., Lark, M.W., Sandy, J.D., Wu, J.J., Eyre, D.R., and Grodzinsky, A.J. Changes in cartilage composition and physical properties due to stromelysin degradation. Arthritis Rheum 38, 173, 1995.
13. Zhu, W., Mow, V.C., Koob, T.J., and Eyre, D.R. Viscoelastic shear properties of articular cartilage and the effects of gly-cosidase treatments. J Orthop Res 11, 771, 1993.
14. Benya, P.D., and Shaffer, J.D. Dedifferentiated chondrocytes reexpress the differentiated collagen phenotype when cultured in agarose gels. Cell 30, 215, 1982.
15. Aydelotte, M.B., Schleyerbach, R., Zeck, B.J., and Kuettner, K.E. Articular chondrocytes cultured in agarose gel for study of chondrocytic chondrolysis. In: Kuettner, K., ed. Articular Cartilage Biochemistry. New York: Raven Press, 1986, pp. 235-256.
16. Buschmann, M.D., Gluzband, Y.A., Grodzinsky, A.J., Kimura, J.H., and Hunziker, E.B. Chondrocytes in agarose culture synthesize a mechanically functional extracellular matrix. J Orthop Res 10, 745, 1992.
17. Lee, D.A., and Bader, D.L. The development and characterization of an in vitro system to study strain-induced cell deformation in isolated chondrocytes. In Vitro Cell Dev Biol Anim 31, 828, 1995.
18. Mauck, R.L., Soltz, M.A., Wang, C.C-B., Wong, D.D., Chao, P.-H.G., Valhmu, W.B., Hung, C.T., and Ateshian, G.A. Functional tissue engineering of articular cartilage through dynamic loading of chondrocyte-seeded agarose gels. J Biomech Eng 122, 252, 2000.
19. Ait Si Selmi, T., Neyret, P.h., Verdonk, P.C.M., and Barnouin, L. Autologous chondrocyte transplantation in combination with an alginate-agarose based hydrogel (Car-tipatch). Techn Knee Surg 6, 253, 2007.
20. Selmi, T.A., Verdonk, P.C.M., Chambat, P., Dubrana, F., Potel, J.F., Barnouin, L., and Neyret, P. Autologous chondrocyte implantation in a novel alginate-agarose hydrogel: outcome at two years. J Bone Joint Surg 90, 597, 2008.
21. Lima, E.G., Tan, A.R., Tai, T., Bian, L., Stoker, A.M., Ateshian, G.A., Cook, J.L., and Hung, C.T. Differences in interleukin-1 response between engineered and native cartilage. Tissue Eng 14, 1721, 2008.
22. Kelly, T.A., Ng, K.W., Wang, C.C., Ateshian, G.A., and Hung, C.T. Spatial and temporal development of chondrocyte-seeded agarose constructs in free-swelling and dynamically loaded cultures. J Biomech 39, 1489, 2006.
23. Morrice, L.M., McLean, M.W., Williamson, F.B., and Long, W.F. beta-Agarases I and II from Pseudomonas atlantica. Purifications and some properties. Eur J Biochem/FEBS 135, 553, 1983.
24. Duckworth, M., and Turvey, J.R. The action of a bacterial agarase on agarose, porphyran and alkali-treated por-phyran. Biochem J 113, 687, 1969.
25. Ng, K.W., Kugler, L.E., Doty, S.B., Ateshian, G.A., and Hung, C.T. Scaffold degradation elevates the collagen content and dynamic compressive modulus in engineered articular cartilage. Osteoarthritis Cartilage/OARS, Osteoarthritis Res Soc; Doi:10.1016/j.joca.2008.06.013.
26. McGowan, K.B., Kurtis, M.S., Lottman, L.M., Watson, D., and Sah, R.L. Biochemical quantification of DNA in human articular and septal cartilage using PicoGreen and Hoechst 33258. Osteoarthritis Cartilage/OARS, Osteoarthritis Res Soc 10, 580, 2002.
27. Farndale, R.W., Buttle, D.J., and Barrett, A.J. Improved quantitation and discrimination of sulphated glycosaminoglycans by use of dimethylmethylene blue. Biochim Biophys Acta 883, 173, 1986.
28. Hollander, A.P., Heathfield, T.F., Webber, C., Iwata, Y., Bourne, R., Rorabeck, C., and Poole, A.R. Increased damage to type II collagen in osteoarthritic articular cartilage detected by a new immunoassay. J Clin Invest 93, 1722, 1994.
29. Bian, L., Kaplun, M., Williams, D.Y., Xu, D., Ateshian, G.A., and Hung, C.T. Influence of chondroitin sulfate on the biochemical, mechanical and frictional properties of cartilage explants in long term culture. J Biomech; Doi: 10.1016/j.jbiomech.2008.10.032.
30. Bian, L., Lima, E.G., Angione, S.L., Ng, K.W., Williams, D.Y., Xu, D., Stoker, A.M., Cook, J.L., Ateshian, G.A., and Hung, C.T. Mechanical and biochemical characterization of cartilage explants in serum-free culture. J Biomech 41, 1153, 2008.
31. Bian, L., Angione, S.L., Ng, K.W., Lima, E.G., Williams, D.Y., Mao, D.Q., Ateshian, G.A., and Hung, C.T. Influence of decreasing nutrient path length on the development of engineered cartilage. Osteoarthritis Cartilage/OARS, Osteoarthritis Res Soc; 10.1016/j.joca.2008.10.003.
32. Williamson, A.K., Masuda, K., Thonar, E.J., and Sah, R.L. Growth of immature articular cartilage in vitro: correlated variation in tensile biomechanical and collagen network properties. Tissue Eng 9, 625, 2003.
33. Park, S., and Ateshian, G.A. Dynamic response of immature bovine articular cartilage in tension and compression, and nonlinear viscoelastic modeling of the tensile response. J Biomech Eng 128, 623, 2006.
34. Huang, C.Y., Stankiewicz, A., Ateshian, G.A., and Mow, V.C. Anisotropy, inhomogeneity, and tension-compression nonlinearity of human glenohumeral cartilage in finite deformation. J Biomech 38, 799, 2005.
35. Palmoski, M., Perricone, E., and Brandt, K.D. Development and reversal of a proteoglycan aggregation defect in normal canine knee cartilage after immobilization. Arthritis Rheum 22, 508, 1979.
36. Setton, L.A., Mow, V.C., and Howell, D.S. Mechanical behavior of articular cartilage in shear is altered by transection of the anterior cruciate ligament. J Orthop Res 13, 473, 1995.
37. Guilak, F., Meyer, B.C., Ratcliffe, A., and Mow, V.C. The effects of matrix compression on proteoglycan metabolism in articular cartilage explants. Osteoarthritis Cartilage 2, 91, 1994.
38. Sah, R.L., Kim, Y.J., Doong, J.Y., Grodzinsky, A.J., Plaas, A.H., and Sandy, J.D. Biosynthetic response of cartilage explants to dynamic compression. J Orthop Res 7, 619, 1989.
39. Sah, R.L., Doong, J.Y., Grodzinsky, A.J., Plaas, A.H., and Sandy, J.D. Effects of compression on the loss of newly synthesized proteoglycans and proteins from cartilage ex-plants. Arch Biochem Biophys 286, 20, 1991.
40. Buschmann, M.D., Kim, Y.J., Wong, M., Frank, E., Hunziker, E.B., and Grodzinsky, A.J. Stimulation of aggrecan synthesis in cartilage explants by cyclic loading is localized to regions of high interstitial fluid flow. Arch Biochem Biophys 366, 1, 1999.
41. Lee, D.A., and Bader, D.L. Compressive strains at physiological frequencies influence the metabolism of chondrocytes seeded in agarose. J Orthop Res 15, 181, 1997.