Acid-catalyzed N-alkylation of tosylhydrazones using benzylic alcohols

Tetrahedron Letters

Volumn 50, Issue 40, 2009, Pages 5633-5635

  Reddy, Ch Raji ^a   Jithender, E ^a  

^a INDIAN INSTITUTE OF CHEMICAL TECHNOLOGY   (India)

Author keywords

Acid catalysis; Benzylic alcohols; N alkylation; Tosylhydrazones; Tris(pentafluorophenyl) borane

Indexed keywords

ALKYLATING AGENT; BENZYL ALCOHOL DERIVATIVE; BORANE DERIVATIVE; HYDRAZONE DERIVATIVE; TOSYLHYDRAZONE DERIVATIVE; TRIS(PENTAFLUOROPHENYL)BORANE DERIVATIVE; UNCLASSIFIED DRUG;

ALKYLATION; ARTICLE; CATALYSIS; REACTION ANALYSIS; REACTION OPTIMIZATION; SYNTHESIS;

EID: 68749098318     PISSN: 00404039     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.tetlet.2009.07.093     Document Type: Article

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17. The enantioselectivity was checked using chiral HPLC: chiral pak IA 250 × 4.6 mm, 5 μ, mobile phase: 5% iso-propanol in hexanes, flow rate: 1 mL/min., retention time: 15.50 (47.4%), 23.15 (52.5%).
18. 2SNa: 487.1456; found: 487.1469.