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Volumn 219, Issue 1, 2009, Pages 163-174

A polysialic acid mimetic peptide promotes functional recovery in a mouse model of spinal cord injury

Author keywords

Glial scar; Mimetic peptide; Polysialic acid NCAM; SCI improvement; Serotonergic neurons; Spinal cord injury

Indexed keywords

NERVE CELL ADHESION MOLECULE; PEPTIDOMIMETIC AGENT; PR 21; UNCLASSIFIED DRUG;

EID: 68749097493     PISSN: 00144886     EISSN: 10902430     Source Type: Journal    
DOI: 10.1016/j.expneurol.2009.05.009     Document Type: Article
Times cited : (42)

References (53)
  • 1
    • 4644338623 scopus 로고    scopus 로고
    • Axon behaviour at Schwann cell-astrocyte boundaries: manipulation of axon signalling pathways and the neural adhesion molecule L1 can enable axons to cross
    • Adcock K.H., Brown D.J., Shearer M.C., Shewan D., Schachner M., Smith G.M., Geller H.M., and Fawcett J.W. Axon behaviour at Schwann cell-astrocyte boundaries: manipulation of axon signalling pathways and the neural adhesion molecule L1 can enable axons to cross. Eur. J. Neurosci. 20 (2004) 1425-1435
    • (2004) Eur. J. Neurosci. , vol.20 , pp. 1425-1435
    • Adcock, K.H.1    Brown, D.J.2    Shearer, M.C.3    Shewan, D.4    Schachner, M.5    Smith, G.M.6    Geller, H.M.7    Fawcett, J.W.8
  • 2
    • 0028805498 scopus 로고
    • Expression of human metallothionein-III confers protection against serum-free exposure of stably transfected Chinese hamster ovary CHO-K1 cells
    • Amoureux M.C., Wurch T., and Pauwels P.J. Expression of human metallothionein-III confers protection against serum-free exposure of stably transfected Chinese hamster ovary CHO-K1 cells. Neurosci. Lett. 201 (1995) 61-64
    • (1995) Neurosci. Lett. , vol.201 , pp. 61-64
    • Amoureux, M.C.1    Wurch, T.2    Pauwels, P.J.3
  • 3
    • 0034657697 scopus 로고    scopus 로고
    • N-CAM binding inhibits the proliferation of hippocampal progenitor cells and promotes their differentiation to a neuronal phenotype
    • Amoureux M.C., Cunningham B.A., Edelman G.M., and Crossin K.L. N-CAM binding inhibits the proliferation of hippocampal progenitor cells and promotes their differentiation to a neuronal phenotype. J. Neurosci. 20 (2000) 3631-3640
    • (2000) J. Neurosci. , vol.20 , pp. 3631-3640
    • Amoureux, M.C.1    Cunningham, B.A.2    Edelman, G.M.3    Crossin, K.L.4
  • 4
    • 20444461041 scopus 로고    scopus 로고
    • Long-lasting recovery of locomotor function in chronic spinal rat following chronic combined pharmacological stimulation of serotonergic receptors with 8-OHDPAT and quipazine
    • Antri M., Barthe J.Y., Mouffle C., and Orsal D. Long-lasting recovery of locomotor function in chronic spinal rat following chronic combined pharmacological stimulation of serotonergic receptors with 8-OHDPAT and quipazine. Neurosci. Lett. 384 (2005) 162-167
    • (2005) Neurosci. Lett. , vol.384 , pp. 162-167
    • Antri, M.1    Barthe, J.Y.2    Mouffle, C.3    Orsal, D.4
  • 5
    • 0032517150 scopus 로고    scopus 로고
    • Expression of L1 and PSA during sprouting and regeneration in the adult hippocampal formation
    • Aubert I., Ridet J.L., Schachner M., Rougon G., and Gage F.H. Expression of L1 and PSA during sprouting and regeneration in the adult hippocampal formation. J. Comp. Neurol. 399 (1998) 1-19
    • (1998) J. Comp. Neurol. , vol.399 , pp. 1-19
    • Aubert, I.1    Ridet, J.L.2    Schachner, M.3    Rougon, G.4    Gage, F.H.5
  • 7
    • 33645983692 scopus 로고    scopus 로고
    • Basso Mouse Scale for locomotion detects differences in recovery after spinal cord injury in five common mouse strains
    • Basso D.M., Fisher L.C., Anderson A.J., Jakeman L.B., McTigue D.M., and Popovich P.G. Basso Mouse Scale for locomotion detects differences in recovery after spinal cord injury in five common mouse strains. J. Neurotrauma 23 (2006) 569-635
    • (2006) J. Neurotrauma , vol.23 , pp. 569-635
    • Basso, D.M.1    Fisher, L.C.2    Anderson, A.J.3    Jakeman, L.B.4    McTigue, D.M.5    Popovich, P.G.6
  • 8
    • 0030887348 scopus 로고    scopus 로고
    • 140 interacts with the focal adhesion kinase p125(fak) and the SRC-related tyrosine kinase p59(fyn)
    • 140 interacts with the focal adhesion kinase p125(fak) and the SRC-related tyrosine kinase p59(fyn). J. Biol. Chem. 272 (1997) 8310-8319
    • (1997) J. Biol. Chem. , vol.272 , pp. 8310-8319
    • Beggs, H.E.1    Baragona, S.C.2    Hemperly, J.J.3    Maness, P.F.4
  • 9
    • 0345689366 scopus 로고    scopus 로고
    • Directed nerve outgrowth is enhanced by engineered glial substrates
    • Biran R., Noble M.D., and Tresco P.A. Directed nerve outgrowth is enhanced by engineered glial substrates. Exp. Neurol. 184 (2003) 141-512
    • (2003) Exp. Neurol. , vol.184 , pp. 141-512
    • Biran, R.1    Noble, M.D.2    Tresco, P.A.3
  • 11
    • 4544373293 scopus 로고    scopus 로고
    • Long-term changes in the molecular composition of the glial scar and progressive increase of serotonergic fibre sprouting after hemisection of the mouse spinal cord
    • Camand E., Morel M.P., Faissner A., Sotelo C., and Dusart I. Long-term changes in the molecular composition of the glial scar and progressive increase of serotonergic fibre sprouting after hemisection of the mouse spinal cord. Eur. J. Neurosci. 20 (2004) 1161-1176
    • (2004) Eur. J. Neurosci. , vol.20 , pp. 1161-1176
    • Camand, E.1    Morel, M.P.2    Faissner, A.3    Sotelo, C.4    Dusart, I.5
  • 12
    • 0033532497 scopus 로고    scopus 로고
    • Late axonal sprouting of injured Purkinje cells and its temporal correlation with permissive changes in the glial scar
    • Dusart I., Morel M.P., Wehrle R., and Sotelo C. Late axonal sprouting of injured Purkinje cells and its temporal correlation with permissive changes in the glial scar. J. Comp. Neurol. 408 (1999) 399-418
    • (1999) J. Comp. Neurol. , vol.408 , pp. 399-418
    • Dusart, I.1    Morel, M.P.2    Wehrle, R.3    Sotelo, C.4
  • 14
    • 33744827677 scopus 로고    scopus 로고
    • Post-training intrahippocampal injection of synthetic poly-alpha-2,8-sialic acid-neural cell adhesion molecule mimetic peptide improves spatial long-term performance in mice
    • Florian C., Foltz J., Norreel J.C., Rougon G., and Roullet P. Post-training intrahippocampal injection of synthetic poly-alpha-2,8-sialic acid-neural cell adhesion molecule mimetic peptide improves spatial long-term performance in mice. Learn Mem. 13 (2006) 335-431
    • (2006) Learn Mem. , vol.13 , pp. 335-431
    • Florian, C.1    Foltz, J.2    Norreel, J.C.3    Rougon, G.4    Roullet, P.5
  • 15
    • 0028807384 scopus 로고
    • Rapid, widespread, and longlasting induction of nestin contributes to the generation of glial scar tissue after CNS injury
    • Frisen J., Johansson C.B., Torok C., Risling M., and Lendahl U. Rapid, widespread, and longlasting induction of nestin contributes to the generation of glial scar tissue after CNS injury. J. Cell Biol. 131 (1995) 453-464
    • (1995) J. Cell Biol. , vol.131 , pp. 453-464
    • Frisen, J.1    Johansson, C.B.2    Torok, C.3    Risling, M.4    Lendahl, U.5
  • 16
    • 0036824323 scopus 로고    scopus 로고
    • Cellular bases of a vertebrate locomotor system-steering, intersegmental and segmental co-ordination and sensory control
    • Grillner S., and Wallen P. Cellular bases of a vertebrate locomotor system-steering, intersegmental and segmental co-ordination and sensory control. Brain Res. Brain Res. Rev. 40 (2002) 92-106
    • (2002) Brain Res. Brain Res. Rev. , vol.40 , pp. 92-106
    • Grillner, S.1    Wallen, P.2
  • 17
    • 0036282045 scopus 로고    scopus 로고
    • Changes in serotonin, serotonin transporter expression and serotonin denervation supersensitivity: involvement in chronic central pain after spinal hemisection in the rat
    • Hains B.C., Everhart A.W., Fullwood S.D., and Hulsebosch C.E. Changes in serotonin, serotonin transporter expression and serotonin denervation supersensitivity: involvement in chronic central pain after spinal hemisection in the rat. Exp. Neurol. 175 (2002) 347-362
    • (2002) Exp. Neurol. , vol.175 , pp. 347-362
    • Hains, B.C.1    Everhart, A.W.2    Fullwood, S.D.3    Hulsebosch, C.E.4
  • 18
    • 38349182183 scopus 로고    scopus 로고
    • Dissecting polysialic acid and NCAM functions in brain development
    • Hildebrandt H., Muhlenhoff M., Weinhold B., and Gerardy-Schahn R. Dissecting polysialic acid and NCAM functions in brain development. J. Neurochem. 103 Suppl. 1 (2007) 56-64
    • (2007) J. Neurochem. , vol.103 , Issue.SUPPL. 1 , pp. 56-64
    • Hildebrandt, H.1    Muhlenhoff, M.2    Weinhold, B.3    Gerardy-Schahn, R.4
  • 19
    • 0028889876 scopus 로고
    • Transient upregulation of NCAM mRNA in astrocytes in response to entorhinal cortex lesions and ischemia
    • Jucker M., Mondadori C., Mohajeri H., Bartsch U., and Schachner M. Transient upregulation of NCAM mRNA in astrocytes in response to entorhinal cortex lesions and ischemia. Brain Res. Mol. Brain Res. 28 (1995) 149-156
    • (1995) Brain Res. Mol. Brain Res. , vol.28 , pp. 149-156
    • Jucker, M.1    Mondadori, C.2    Mohajeri, H.3    Bartsch, U.4    Schachner, M.5
  • 20
    • 0035215303 scopus 로고    scopus 로고
    • Contribution of the neural cell adhesion molecule to neuronal and synaptic plasticity
    • Kiss J.Z., and Muller D. Contribution of the neural cell adhesion molecule to neuronal and synaptic plasticity. Rev. Neurosci. 12 (2001) 297-310
    • (2001) Rev. Neurosci. , vol.12 , pp. 297-310
    • Kiss, J.Z.1    Muller, D.2
  • 21
  • 22
    • 1342310622 scopus 로고    scopus 로고
    • Glycans and neural cell interactions
    • Kleene R., and Schachner M. Glycans and neural cell interactions. Nat. Rev. Neurosci. 5 (2004) 195-208
    • (2004) Nat. Rev. Neurosci. , vol.5 , pp. 195-208
    • Kleene, R.1    Schachner, M.2
  • 24
    • 0026886364 scopus 로고
    • Involvement of 5-hydroxytryptamine1A receptors in the modulation of micturition reflexes in the anesthetized rat
    • Lecci A., Giuliani S., Santicioli P., and Maggi C.A. Involvement of 5-hydroxytryptamine1A receptors in the modulation of micturition reflexes in the anesthetized rat. J. Pharmacol. Exp. Ther. 262 (1992) 181-189
    • (1992) J. Pharmacol. Exp. Ther. , vol.262 , pp. 181-189
    • Lecci, A.1    Giuliani, S.2    Santicioli, P.3    Maggi, C.A.4
  • 25
    • 34247585173 scopus 로고    scopus 로고
    • Recognition molecules and neural repair
    • Loers G., and Schachner M. Recognition molecules and neural repair. J. Neurochem. 101 (2007) 865-882
    • (2007) J. Neurochem. , vol.101 , pp. 865-882
    • Loers, G.1    Schachner, M.2
  • 26
    • 33646467354 scopus 로고    scopus 로고
    • Targeting melanoma cells with human high molecular weight-melanoma associated antigen-specific antibodies elicited by a peptide mimotope: functional effects
    • Luo W., Ko E., Hsu J.C., Wang X., and Ferrone S. Targeting melanoma cells with human high molecular weight-melanoma associated antigen-specific antibodies elicited by a peptide mimotope: functional effects. J. Immunol. 176 (2006) 6046-6054
    • (2006) J. Immunol. , vol.176 , pp. 6046-6054
    • Luo, W.1    Ko, E.2    Hsu, J.C.3    Wang, X.4    Ferrone, S.5
  • 27
    • 0034982490 scopus 로고    scopus 로고
    • Behavioral and histological outcomes following graded spinal cord contusion injury in the C57Bl/6 mouse
    • Ma M., Basso D.M., Walters P., Stokes B.T., and Jakeman L.B. Behavioral and histological outcomes following graded spinal cord contusion injury in the C57Bl/6 mouse. Exp. Neurol. 169 (2001) 239-254
    • (2001) Exp. Neurol. , vol.169 , pp. 239-254
    • Ma, M.1    Basso, D.M.2    Walters, P.3    Stokes, B.T.4    Jakeman, L.B.5
  • 28
    • 0028109453 scopus 로고
    • Multiple receptor-like protein tyrosine phosphatases in the form of chondroitin sulfate proteoglycan
    • Maeda N., Hamanaka H., Shintani T., Nishiwaki T., and Noda M. Multiple receptor-like protein tyrosine phosphatases in the form of chondroitin sulfate proteoglycan. FEBS Lett. 354 (1994) 67-70
    • (1994) FEBS Lett. , vol.354 , pp. 67-70
    • Maeda, N.1    Hamanaka, H.2    Shintani, T.3    Nishiwaki, T.4    Noda, M.5
  • 29
    • 0028222117 scopus 로고
    • Cell adhesion alters gene transcription in chicken embryo brain cells and mouse embryonal carcinoma cells
    • Mauro V.P., Wood I.C., Krushel L., Crossin K.L., and Edelman G.M. Cell adhesion alters gene transcription in chicken embryo brain cells and mouse embryonal carcinoma cells. Proc. Natl. Acad. Sci. U. S. A. 91 (1994) 2868-2872
    • (1994) Proc. Natl. Acad. Sci. U. S. A. , vol.91 , pp. 2868-2872
    • Mauro, V.P.1    Wood, I.C.2    Krushel, L.3    Crossin, K.L.4    Edelman, G.M.5
  • 30
    • 0041806517 scopus 로고    scopus 로고
    • Axonal plasticity and functional recovery after spinal cord injury in mice deficient in both glial fibrillary acidic protein and vimentin genes
    • Menet V., Prieto M., Privat A., and Gimenez y Ribotta M. Axonal plasticity and functional recovery after spinal cord injury in mice deficient in both glial fibrillary acidic protein and vimentin genes. Proc. Natl. Acad. Sci. U. S. A. 100 (2003) 8999-9004
    • (2003) Proc. Natl. Acad. Sci. U. S. A. , vol.100 , pp. 8999-9004
    • Menet, V.1    Prieto, M.2    Privat, A.3    Gimenez y Ribotta, M.4
  • 31
    • 0035201532 scopus 로고    scopus 로고
    • Selection of phage-displayed peptides recognised by monoclonal antibodies directed against the lipopolysaccharide of Brucella
    • Mertens P., Walgraffe D., Laurent T., Deschrevel N., Letesson J.J., and De Bolle X. Selection of phage-displayed peptides recognised by monoclonal antibodies directed against the lipopolysaccharide of Brucella. Int. Rev. Immunol. 20 (2001) 181-199
    • (2001) Int. Rev. Immunol. , vol.20 , pp. 181-199
    • Mertens, P.1    Walgraffe, D.2    Laurent, T.3    Deschrevel, N.4    Letesson, J.J.5    De Bolle, X.6
  • 32
    • 43949090500 scopus 로고    scopus 로고
    • Impact of associated conditions resulting from spinal cord injury on health status and quality of life in people with traumatic central cord syndrome
    • Noonan V.K., Kopec J.A., Zhang H., and Dvorak M.F. Impact of associated conditions resulting from spinal cord injury on health status and quality of life in people with traumatic central cord syndrome. Arch. Phys. Med. Rehabil. 89 (2008) 1074-1082
    • (2008) Arch. Phys. Med. Rehabil. , vol.89 , pp. 1074-1082
    • Noonan, V.K.1    Kopec, J.A.2    Zhang, H.3    Dvorak, M.F.4
  • 33
    • 0037336703 scopus 로고    scopus 로고
    • Reversible disorganization of the locomotor pattern after neonatal spinal cord transection in the rat
    • Norreel J.C., Pflieger J.F., Pearlstein E., Simeoni-Alias J., Clarac F., and Vinay L. Reversible disorganization of the locomotor pattern after neonatal spinal cord transection in the rat. J. Neurosci. 23 (2003) 1924-1932
    • (2003) J. Neurosci. , vol.23 , pp. 1924-1932
    • Norreel, J.C.1    Pflieger, J.F.2    Pearlstein, E.3    Simeoni-Alias, J.4    Clarac, F.5    Vinay, L.6
  • 34
    • 34547752447 scopus 로고    scopus 로고
    • Grafts of Schwann cells engineered to express PSA-NCAM promote functional recovery after spinal cord injury
    • Papastefanaki F., Chen J., Lavdas A.A., Thomaidou D., Schachner M., and Matsas R. Grafts of Schwann cells engineered to express PSA-NCAM promote functional recovery after spinal cord injury. Brain 130 (2007) 2159-2174
    • (2007) Brain , vol.130 , pp. 2159-2174
    • Papastefanaki, F.1    Chen, J.2    Lavdas, A.A.3    Thomaidou, D.4    Schachner, M.5    Matsas, R.6
  • 37
    • 0023029232 scopus 로고
    • A monoclonal antibody against meningococcus group B polysaccharides distinguishes embryonic from adult N-CAM
    • Rougon G., Dubois C., Buckley N., Magnani J.L., and Zollinger W. A monoclonal antibody against meningococcus group B polysaccharides distinguishes embryonic from adult N-CAM. J. Cell Biol. 103 (1986) 2429-2437
    • (1986) J. Cell Biol. , vol.103 , pp. 2429-2437
    • Rougon, G.1    Dubois, C.2    Buckley, N.3    Magnani, J.L.4    Zollinger, W.5
  • 38
    • 0025513601 scopus 로고
    • Inhibition of neurite outgrowth on astroglial scars in vitro
    • Rudge J.S., and Silver J. Inhibition of neurite outgrowth on astroglial scars in vitro. J. Neurosci. 10 (1990) 3594-3603
    • (1990) J. Neurosci. , vol.10 , pp. 3594-3603
    • Rudge, J.S.1    Silver, J.2
  • 39
    • 37349120002 scopus 로고    scopus 로고
    • Polysialic acid in the plasticity of the developing and adult vertebrate nervous system
    • Rutishauser U. Polysialic acid in the plasticity of the developing and adult vertebrate nervous system. Nat. Rev. Neurosci. 9 (2008) 26-35
    • (2008) Nat. Rev. Neurosci. , vol.9 , pp. 26-35
    • Rutishauser, U.1
  • 40
    • 0036906389 scopus 로고    scopus 로고
    • Identification of a peptide mimic of the L2/HNK-1 carbohydrate epitope
    • Simon-Haldi M., Mantei N., Franke J., Voshol H., and Schachner M. Identification of a peptide mimic of the L2/HNK-1 carbohydrate epitope. J. Neurochem. 83 (2002) 1380-1388
    • (2002) J. Neurochem. , vol.83 , pp. 1380-1388
    • Simon-Haldi, M.1    Mantei, N.2    Franke, J.3    Voshol, H.4    Schachner, M.5
  • 41
    • 0036797791 scopus 로고    scopus 로고
    • A statistical method for analyzing rating scale data: the BBB locomotor score
    • Scheff S.W., Saucier D.A., and Cain M.E. A statistical method for analyzing rating scale data: the BBB locomotor score. J. Neurotrauma. 19 (2002) 1251-1260
    • (2002) J. Neurotrauma. , vol.19 , pp. 1251-1260
    • Scheff, S.W.1    Saucier, D.A.2    Cain, M.E.3
  • 42
    • 0742288565 scopus 로고    scopus 로고
    • Regeneration beyond the glial scar
    • Silver J., and Miller J.H. Regeneration beyond the glial scar. Nat. Rev. Neurosci. 5 (2004) 146-516
    • (2004) Nat. Rev. Neurosci. , vol.5 , pp. 146-516
    • Silver, J.1    Miller, J.H.2
  • 43
    • 0032538550 scopus 로고    scopus 로고
    • A role for polysialic acid in neural cell adhesion molecule heterophilic binding to proteoglycans
    • Storms S.D., and Rutishauser U. A role for polysialic acid in neural cell adhesion molecule heterophilic binding to proteoglycans. J. Biol. Chem. 273 (1998) 27124-27129
    • (1998) J. Biol. Chem. , vol.273 , pp. 27124-27129
    • Storms, S.D.1    Rutishauser, U.2
  • 45
    • 3142735056 scopus 로고    scopus 로고
    • Selection of poly-alpha 2,8-sialic acid mimotopes from a random phage peptide library and analysis of their bioactivity
    • Torregrossa P., Buhl L., Bancila M., Durbec P., Schafer C., Schachner M., and Rougon G. Selection of poly-alpha 2,8-sialic acid mimotopes from a random phage peptide library and analysis of their bioactivity. J. Biol. Chem. 279 (2004) 30707-30714
    • (2004) J. Biol. Chem. , vol.279 , pp. 30707-30714
    • Torregrossa, P.1    Buhl, L.2    Bancila, M.3    Durbec, P.4    Schafer, C.5    Schachner, M.6    Rougon, G.7
  • 46
    • 0035910308 scopus 로고    scopus 로고
    • Expression of neural cell adhesion molecule in spinal cords following a complete transection
    • Tzeng S.F., Cheng H., Lee Y.S., Wu J.P., Hoffer B.J., and Kuo J.S. Expression of neural cell adhesion molecule in spinal cords following a complete transection. Life Sci. 68 (2001) 1005-1012
    • (2001) Life Sci. , vol.68 , pp. 1005-1012
    • Tzeng, S.F.1    Cheng, H.2    Lee, Y.S.3    Wu, J.P.4    Hoffer, B.J.5    Kuo, J.S.6
  • 47
    • 0028851543 scopus 로고
    • FGF inhibits neurite outgrowth over monolayers of astrocytes and fibroblasts expressing transfected cell adhesion molecules
    • Williams E.J., Mittal B., Walsh F.S., and Doherty P. FGF inhibits neurite outgrowth over monolayers of astrocytes and fibroblasts expressing transfected cell adhesion molecules. J. Cell Sci. 108 (1995) 3523-3530
    • (1995) J. Cell Sci. , vol.108 , pp. 3523-3530
    • Williams, E.J.1    Mittal, B.2    Walsh, F.S.3    Doherty, P.4
  • 48
    • 0031753291 scopus 로고    scopus 로고
    • A culture model of reactive astrocytes: increased nerve growth factor synthesis and reexpression of cytokine responsiveness
    • Wu V.W., Nishiyama N., and Schwartz J.P. A culture model of reactive astrocytes: increased nerve growth factor synthesis and reexpression of cytokine responsiveness. J. Neurochem. 71 (1998) 749-756
    • (1998) J. Neurochem. , vol.71 , pp. 749-756
    • Wu, V.W.1    Nishiyama, N.2    Schwartz, J.P.3
  • 49
    • 38649122410 scopus 로고    scopus 로고
    • White matter inhibitors in CNS axon regeneration failure
    • Xie F., and Zheng B. White matter inhibitors in CNS axon regeneration failure. Exp. Neurol. 209 (2008) 132-302
    • (2008) Exp. Neurol. , vol.209 , pp. 132-302
    • Xie, F.1    Zheng, B.2
  • 50
    • 33746308062 scopus 로고    scopus 로고
    • Glial inhibition of CNS axon regeneration
    • Yiu G., and He Z. Glial inhibition of CNS axon regeneration. Nat. Rev. Neurosci. 7 (2006) 267-617
    • (2006) Nat. Rev. Neurosci. , vol.7 , pp. 267-617
    • Yiu, G.1    He, Z.2
  • 51
    • 16344387685 scopus 로고    scopus 로고
    • X-irradiation reduces lesion scarring at the contusion site of adult rat spinal cord
    • Zhang S.X., Geddes J.W., Owens J.L., and Holmberg E.G. X-irradiation reduces lesion scarring at the contusion site of adult rat spinal cord. Histol. Histopathol. 20 (2005) 350-519
    • (2005) Histol. Histopathol. , vol.20 , pp. 350-519
    • Zhang, S.X.1    Geddes, J.W.2    Owens, J.L.3    Holmberg, E.G.4
  • 52
    • 34548731859 scopus 로고    scopus 로고
    • Lentiviral-mediated expression of polysialic acid in spinal cord and conditioning lesion promote regeneration of sensory axons into spinal cord
    • Zhang Y., Zhang X., Wu D., Verhaagen J., Richardson P.M., Yeh J., and Bo X. Lentiviral-mediated expression of polysialic acid in spinal cord and conditioning lesion promote regeneration of sensory axons into spinal cord. Mol. Ther. 15 (2007) 1796-1804
    • (2007) Mol. Ther. , vol.15 , pp. 1796-1804
    • Zhang, Y.1    Zhang, X.2    Wu, D.3    Verhaagen, J.4    Richardson, P.M.5    Yeh, J.6    Bo, X.7
  • 53
    • 34247369382 scopus 로고    scopus 로고
    • Induced expression of polysialic acid in the spinal cord promotes regeneration of sensory axons
    • Zhang Y., Ghadiri-Sani M., Zhang X., Richardson P.M., Yeh J., and Bo X. Induced expression of polysialic acid in the spinal cord promotes regeneration of sensory axons. Mol. Cell Neurosci. 35 (2007) 109-119
    • (2007) Mol. Cell Neurosci. , vol.35 , pp. 109-119
    • Zhang, Y.1    Ghadiri-Sani, M.2    Zhang, X.3    Richardson, P.M.4    Yeh, J.5    Bo, X.6


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