Modulator effects of L-carnitine and selenium on wireless devices (2.45 GHz)-induced oxidative stress and electroencephalography records in brain of rat

International Journal of Radiation Biology

Volumn 85, Issue 8, 2009, Pages 680-689

  Naziroǧlu, Mustafa ^a   Gümral, Nurhan ^b  

^a SULEYMAN DEMIREL UNIVERSITY   (Turkey)

^b SULEYMAN DEMIREL UNIVERSITY SCHOOL OF MEDICINE   (Turkey)

Author keywords

Brain; Electroencephalography records; L carnitine; Lipid peroxidation; Selenium; Vitamin E; Wireless devices

Indexed keywords

ALPHA TOCOPHEROL; ASCORBIC ACID; BETA CAROTENE; CARNITINE; FREE RADICAL; GLUTATHIONE; GLUTATHIONE PEROXIDASE; RETINOL; SELENIUM; SODIUM SELENITE;

ANIMAL EXPERIMENT; ANIMAL TISSUE; ANTIOXIDANT ACTIVITY; ARTICLE; BRAIN CORTEX; BRAIN INJURY; CONTROLLED STUDY; DEVICE; ELECTRIC CURRENT; ELECTROENCEPHALOGRAPHY; ELECTROMAGNETIC RADIATION; LIPID PEROXIDATION; MALE; NEUROPROTECTION; NONHUMAN; OXIDATION REDUCTION REACTION; OXIDATIVE STRESS; PRIORITY JOURNAL; RADIATION EXPOSURE; RAT;

ANIMALS; CARNITINE; ELECTROENCEPHALOGRAPHY; GLUTATHIONE; GLUTATHIONE PEROXIDASE; LIPID PEROXIDATION; MALE; OXIDATIVE STRESS; RADIATION-PROTECTIVE AGENTS; RATS; RATS, WISTAR; SELENIUM; VITAMIN E;

RATTUS;

EID: 68749096183     PISSN: 09553002     EISSN: 13623095     Source Type: Journal    
DOI: 10.1080/09553000903009530     Document Type: Article

References (46)

1. Arockia-Rani PJ, Panneerselvam C. 2001. Carnitine as a free radical scavenger in ageing. Experimental Gerontology 36:1713-1726. (Pubitemid 32982875)
2. Arrigoni O, De Tullio MC. 2002. Ascorbic acid: Much more than just an antioxidant. Acta Biochimica Et Biophysica 1569:1-9.
3. Cosquer B, Vasconcelos AP, Fröhlich J, Cassel JC. 2005. Blood-brain barrier and electromagnetic fields: effects of scopolamine methylbromide on working memory after whole-body exposure to 2.45 GHz microwaves in rats. Behavior and Brain Research 161:229-237. (Pubitemid 40732405)
4. Croft RJ, Chandler JS, Burgess AP, Barry RJ, Williams JD, Clarke AR. 2002. Acute mobile phone operation affects neural function in humans. Clinical Neurophysiology 113:1623-1632.
5. Crouzier D, Testylier G, Perrin A, Debouzy JC. 2007. Which neurophysiologic effects at low level 2.45 GHz RF exposure? Pathology of Biology (Paris) 55:235-241.
6. Czernichow S, Hersberg S. 2001. Interventional studies concerning the role of antioxidant vitamins in cardiovascular disease: A review. Journal of Nutrition, Health and Aging 5:188-195. (Pubitemid 32678492)
7. Desai ID. 1984. Vitamin E analysis methods for animal tissues. Methods in Enzymology 105:138-147.
8. Eren I, Naziroglu M, Demirdaş A. 2007. Protective effects of lamotrigine, aripirazole and escitalopram on depression-induced oxidative stress in rat brain. Neurochemical Research 32:1188-1195. (Pubitemid 46817468)
9. Faraone A, Ballen M, Bit-Babik G, Gressner AV, Kanda MY, Swicord ML, Chou CK. 2004. RF dosimetry for the ferriswheel mouse exposure system Motorola Labs Final Report, August.
10. Gajsek P, Ziriax JM, Hurt WD, Walters TJ, Mason PA. 2001. Predicted SAR in Sprague-Dawley rat as a function of permittivity values. Bioelectromagnetics 22:384-400. (Pubitemid 33617701)
11. Gumral N, Naziroǧlu M, Koyu A, Öngel K, Çelik Ö , Saygin M, Kahriman M, Caliskan S, Kayan M, Gencel O, Flores-Arce MF. 2009. Effects of selenium and L-Carnitine on oxidative stress in blood of rat induced by 2.45-GHz radiation from wireless devices. Biol Trace Elem Res (in press).
12. Halliwell B. 2006. Oxidative stress and neurodegeneration: Where are we now? Journal of Neurochemistry 97:1634-1658.
13. Hietanen M, Kovala T, Hämäläinen AM. 2000. Human brain activity during exposure to radiofrequency fields emitted by cellular phones. Scandinavian Journal of Work Environment and Health 26:87-92. (Pubitemid 30229690)
14. Hinrichs H, Noesselt T, Heinze HJ. 2008. Directed information flow: A model free measure to analyze causal interactions in event related EEG-MEG-experiments. Human Brain Mapping 29:193-206. (Pubitemid 351294948)
15. Ilhan A, Gurel A, Armutcu F, Kamisli S, Iraz M, Akyol M, Ozen S. 2004. Ginkgo biloba prevents mobile phone-induced oxidative stress in rat brain. Clinica Chimica Acta 340:153-162. (Pubitemid 38167519)
16. Inazu M, Matsumiya T. 2008. Physiological functions of carnitine and carnitine transporters in the central nervous system. Nihon Shinkei Seishin Yakurigaku Zasshi 28:113-120.
17. Irmak MK, Fadillioglu E, Gulec M, Erdogan H, Yagmurca M, Akyol O. 2002. Effects of electromagnetic radiation from a cellular telephone on the oxidant and antioxidant levels in rabbits. Cell Biochemistry and Function 20:279-283. (Pubitemid 35340062)
18. Jagota SK, Dani HM. 1982. A new colorimetric technique for the estimation of vitamin C using Folin phenol reagent. Analytical Biochemistry 127:178-182.
19. Kharatishvili I, Immonen R, Gröhn O, Pitkänen A. 2007. Quantitative diffusion MRI of hippocampus as a surrogate marker for post-traumatic epileptogenesis. Brain 130: 3155-3168. (Pubitemid 350209080)
20. Kleinlogel H, Dierks T, Koenig T, Lehmann H, Minder A, Berz R. 2008. Effects of weak mobile phone-electromagnetic fields (GSM, UMTS) on well-being and resting EEG. Bioelectromagnetics 29:479-487.
21. Koana T, Okada MO, Ikehata M, Nakagawa M. 1997. Increase in the mitotic recombination frequency in Drosophila melanogaster by magnetic field exposure and its suppression by vitamin E supplement. Mutation Research 373:55-60.
22. Kocer I, Taysi S, Ertekin MV, Karslioglu I, Gepdiremen A, Sezen O, Serifoglu K. 2007. The effect of L-carnitine in the prevention of ionizing radiation-induced cataracts: A rat model. Graefe's Archive for Clinical and Experimental Ophthalmology 245:588-594. (Pubitemid 46477321)
23. Kovacic P, Somanathan R. 2008. Unifying mechanism for eye toxicity: Electron transfer, reactive oxygen species, antioxidant benefits, cell signaling and cell membranes. Cell Membranes and Free Radical Research 2:56-69.
24. Köylü H, Mollaoglu H, Ozguner F, Naziroglu M, Delibas N. 2006. Melatonin modulates 900 Mhz microwave-induced lipid peroxidation changes in rat brain. Toxicology and Industrial Health 22:211-216. (Pubitemid 44081161)
25. Koyu A, Naziroǧlu M, Ozguner F, Yilmaz HR, Uz E, Cesur G. 2005. Caffeic acid phenethyl ester modulates 1800 MHz microwave-induced oxidative stress in rat liver. Electromagnetic in Biology and Medicine 24:135-142. (Pubitemid 41252895)
26. Kuribayashi M, Wang J, Fujiwara O, Doi Y, Nabae K, Tamano S, Ogiso T, Asamoto M, Shirai T. 2005. Lack of effects of 1439 MHz electromagnetic near field exposure on the blood-brain barrier in immature and young rats. Bioelectromagnetics 26:578-588. (Pubitemid 41437413)
27. Lawrence RA, Burk RF. 1976. Glutathione peroxidase activity in selenium-deficient rat liver. Biochemical and Biophysical Research Communications 71:952-958.
28. Lowry OH, Rosebrough NJ, Farr AL, Randall RJ. 1951. Protein measurement with the Folin- Phenol reagent. Journal of Biological Chemistry 193:265-275.
29. Meral I, Mert H, Mert N, Deger Y, Yoruk I, Yetkin A, Keskin S. 2007. Effects of 900-MHz electromagnetic field emitted from cellular phone on brain oxidative stress and some vitamin levels of guinea pigs. Brain Research 1169:120-124. (Pubitemid 47374099)
30. Murphy JC, Kaden DA, Warren J, Sivak A. 1993. International Commission for Protection against Environmental Mutagens and Carcinogens. Power frequency electric and magnetic fields: A review of genetic toxicology. Mutation Research 296:221-240.
31. Naziroǧlu M. 2003. Enhanced testicular antioxidant capacity in streptozotocin-induced diabetic rats: Protective role of vitamins C and E and selenium. Biological Trace Element Research 94:61-72. (Pubitemid 36976457)
32. Naziroǧlu M. 2007a. Molecular mechanisms of vitamin E on intracellular signaling pathways in brain. In: Laszlo Goth, editor. Reactive Oxygen Species and diseases. Kerala, India: Research Signpost Press. pp 239-256.
33. Naziroǧlu M. 2007b. New molecular mechanisms on the activation of TRPM2 channels by oxidative stress and ADP-ribose. Neurochemical Research 32:1990-2001. (Pubitemid 47497894)
34. Naziroǧlu M, Uǧuz AC, Gokçimen A, Bülbül M, Karatopuk DU, Türker Y, Cerçi C. 2008. Tenoxicam modulates antioxidant redox system and lipid peroxidation in rat brain. Neurochemical Research 33:1832-1837.
35. Nittby H, Grafström G, Eberhardt JL, Malmgren L, Brun A, Persson BR, Salford LG. 2008. Radiofrequency and extremely low-frequency electromagnetic field effects on the blood-brain barrier. Electromagnetic in Biology and Medicine 27:103-126. (Pubitemid 351913222)
36. Olatunji-Bello II, Reiter RJ. 1997. Effect of acute acetyl-L-carnitine treatment on daytime melatonin synthesis in the rat. African Journal of Medicine and Medical Sciences 26:175-177.
37. Omura Y, Losco M. 1993. Electro-magnetic fields in the home environment (color TV, computer monitor, microwave oven, cellular phone, etc) as potential contributing factors for the induction of oncogen C-fos Ab1, oncogen C-fos Ab2, alpha 5 beta 1 and development of cancer, as well as effects of microwave on amino acid composition of food and living human brain. Acupuncture Electrotherapy Research 18:33-73. (Pubitemid 23129209)
38. Özmen I, Naziroǧlu M, Alici HA, Sahin F, Cengiz M, Eren İ. 2007. Spinal morphine administration reduces the fatty acid contents in spinal cord and brain in rabbits due to oxidative stress. Neurochemical Research 32:19-25. (Pubitemid 46020927)
39. Placer ZA, Cushman L, Johnson BC. 1966. Estimation of products of lipid peroxidation (malonyl dialdehyde) in biological fluids. Analytical Biochemistry 16:359-364.
40. Rani PJ, Panneerselvam C. 2002. Effect of L-carnitine on brain lipid peroxidation and antioxidant enzymes in old rats. Journals of Gerontology Series A: Biological Sciences and Medical Sciences 57:134-137. (Pubitemid 34263289)
41. Rapacholi MH. 2001. Health risks from the use of mobile phones. Toxicology Letters 31(120):323-331. (Pubitemid 32375099)
42. Röschke J, Mann K. 1997. No effects of digital mobile radio telephone on the awake human electroencephalogram. Bioelectromagnetics 18:172-176.
43. Sedlak J, Lindsay RHC. 1968. Estimation of total, protein bound and non-protein sulfhydryl groups in tissue with Ellmann's reagent. Analytical Biochemistry 25:192-205.
44. Suzuki J, Katoh N. 1990. A simple and cheap method for measuring vitamin A in cattle using only a spectrophotometer. Japanese Journal of Veterinary Research 52:1282-1284.
45. Üçüncü H, Ertekin MV, Yörü k Ö , Sezen O, Özkan A, Erdoǧan F, Kiziltunç A, Gündoǧdu C. 2006. Vitamin E and L-carnitine, separately or in combination, in the prevention of radiation-induced oral mucositis and myelosuppression: A controlled study in a rat model. Journal of Radiation Research 47:91-102.
46. Whanger PD. 2001. Selenium and the brain: A review. Nutritional Neuroscience 4:81-97.