Recruitment of a host's osteoprogenitor cells using exogenous mesenchymal stem cells seeded on porous ceramic

Tissue Engineering - Part A

Volumn 15, Issue 8, 2009, Pages 2203-2212

  Tasso, Roberta ^a,b   Augello, Andrea ^a,b   Boccardo, Simona ^b   Salvi, Sandra ^b   Caridà, Michela ^a,b   Postiglione, Fabio ^a,b   Fais, Franco ^a   Truini, Mauro ^b   Cancedda, Ranieri ^a,b   Pennesi, Giuseppina ^a,b,c  

^a UNIVERSITY OF GENOA   (Italy)

^b UNIVERSITY OF GENOA   (Italy)

^c ADVANCED BIOTECHNOLOGY CENTER   (Italy)

Author keywords

[No Author keywords available]

Indexed keywords

ANIMALS; BONE; CELL CULTURE; EMPLOYMENT; FLOWCHARTING; HYDROXYAPATITE; REPAIR; SCAFFOLDS; TISSUE ENGINEERING;

ALLOGENIC CELLS; AUTOLOGOUS CELL; BIO-SCAFFOLDS; BONE DEFECT; BONE REPAIR; BONE TISSUE; CIRCULATING PROGENITOR CELLS; CIRCULATORY FLOW; CLINICAL APPLICATION; MESENCHYMAL STEM CELL; OSTEOPROGENITOR CELLS; OSTEOPROGENITORS; POROUS CERAMICS; RECRUITMENT PROCESS; TISSUE DEVELOPMENT;

CELL MEMBRANES;

ALLOANTIBODY; ASCORBIC ACID; CYTOKINE; DEXAMETHASONE; GAMMA INTERFERON; GLYCEROL 2 PHOSPHATE; HYDROXYAPATITE; IMMUNOSUPPRESSIVE AGENT; INTERLEUKIN 2; TRANSFORMING GROWTH FACTOR BETA1; TUMOR NECROSIS FACTOR ALPHA;

ACUTE GRAFT REJECTION; ANIMAL CELL; ANIMAL EXPERIMENT; ARTICLE; BONE DEFECT; BONE REMODELING; BONE TISSUE; CD4+ T LYMPHOCYTE; CERAMICS; CONTROLLED STUDY; CYTOKINE PRODUCTION; ENCHONDRAL OSSIFICATION; ENZYME LINKED IMMUNOSORBENT ASSAY; FLOW CYTOMETRY; HISTOLOGY; IMMUNOPHENOTYPING; IMPLANTATION; MESENCHYMAL STEM CELL; MIXED LYMPHOCYTE REACTION; MOUSE; NONHUMAN; NUDE MOUSE; PRIORITY JOURNAL; SPLEEN CELL; TISSUE ENGINEERING; TISSUE REPAIR;

ANIMALIA; MURINAE;

ANIMALS; CERAMICS; GRAFT REJECTION; IMMUNOCOMPETENCE; IMMUNOPHENOTYPING; IMPLANTS, EXPERIMENTAL; MESENCHYMAL STEM CELL TRANSPLANTATION; MESENCHYMAL STEM CELLS; MICE; MICE, INBRED C57BL; NEOVASCULARIZATION, PHYSIOLOGIC; OSTEOGENESIS; POROSITY; TISSUE SCAFFOLDS; TRANSPLANTATION, HOMOLOGOUS;

EID: 68749095196     PISSN: 19373341     EISSN: 1937335X     Source Type: Journal    
DOI: 10.1089/ten.tea.2008.0269     Document Type: Article

References (28)

1. Wu, Y., Chen, L., Scott, P.G., and Tredget, E.E. Mesenchymal stem cells enhance wound healing through differentiation and angiogenesis. Stem Cells 25, 2648, 2007.
2. Quarto, R., Mastrogiacomo, M., Cancedda, R., Kutepov, S.M., Mukhachev, V., Lavroukov, A., Kon, E., and Marcacci, M. Repair of large bone defects with the use of autologous bone marrow stromal cells. N Engl J Med 344, 385, 2001.
3. Eghbali-Fatourechi, G.Z., Lamsam, J., Fraser, D., Nagel, D., Riggs, B.L., and Khosla, S. Circulating osteoblast-lineage cells in humans. N Engl J Med 352, 1959, 2005.
4. Mastrogiacomo, M., Derubeis, A.R., and Cancedda, R. Bone and cartilage formation by skeletal muscle derived cells. J Cell Physiol 204, 594, 2005.
5. Kuwana, M., Okazaki, Y., Kodama, H., Izumi, K., Yasuoka, H., Ogawa, Y., Kawakami, Y., and Ikeda, Y. Human circulating CD14+ monocytes as a source of progenitors that exhibit mesenchymal cell differentiation. J Leukoc Biol 74, 833, 2003.
6. Muraglia, A., Martin, I., Cancedda, R., and Quarto, R. A nude mouse model for human bone formation in unloaded conditions. Bone 22, 131S, 1998.
7. Uccelli, A., Moretta, L., and Pistoia, V. Mesenchymal stem cells in health and disease. Nat Rev Immunol 2008 Aug 18. [Epub ahead of print].
8. Arinzeh, T.L., Peter, S.J., Archambault, M.P., van den Bos, C., Gordon, S., Kraus, K., Smith, A., and Kadiyala, S. Allogenic mesenchymal stem cells regenerate bone in a critical-sized canine segmental defect. J Bone Joint Surg Am 85-A, 1927, 2003.
9. Liu, H., Kemeny, D.M., Heng, B.C., Ouyang, H.W., Me-lendez, A.J., and Cao, T. The immunogenicity and immu-nomodulatory function of osteogenic cells differentiated from mesenchymal stem cells. J Immunol 176, 2864, 2006.
10. Matsumoto, T., Mifune, Y., Kawamoto, A., Kuroda, R., Shoji, T., Iwasaki, H., Suzuki, T., Oyamada, A., Horii, M., Yokoyama, A., Nishimura, H., Lee, S.Y., Miwa, M., Doita, M., Kurosaka, M., and Asahara, T. Fracture induced mobilization and incorporation of bone marrow-derived endothelial progenitor cells for bone healing. J Cell Physiol 215, 234, 2008.
11. Huang, A.H., Snyder, B.R., Cheng, P.H., and Chan, A.W. Putative dental pulp derived stem/stromal cells promote proliferation and differentiation of endogenous neural cells in the hippocampus of mice. Stem Cells 26, 2654, 2008.
12. Revoltella, R.P., Papini, S., Rosellini, A., Michelini, M., Franceschini, V., Ciorba, A., Bertolaso, L., Magosso, S., Hatzopoulos, S., Lorito, G., Giordano, P., Simoni, E., Ognio, E., Cilli, M., Saccardi, R., Urbani, S., Jeffery, R., Poulsom, R., and Martini, A. Cochlear repair by transplantation of human cord blood CD133+ cells to nod-scid mice made deaf with kanamycin and noise. Cell Transplant 17, 665, 2008.
13. Martin, I., Muraglia, A., Campanile, G., Cancedda, R., and Quarto, R. Fibroblast growth factor-2 supports ex vivo expansion and maintenance of osteogenic precursors from human bone marrow. Endocrinology 138, 4456, 1997.
14. Eljaafari, A., Badet, L., Kanitakis, J., Ferrand, C., Farre, A., Petruzzo, P., Morelon, E., Dubosson, M., Tiberghien, P., Dubois, V., Martin, X., Miossec, P., and Dubernard, J.M. Isolation of regulatory T cells in the skin of a human hand-allograft, up to six years posttransplantation. Transplantation 82, 1764, 2006.
15. Shirley, D., Marsh, D., Jordan, G., McQuaid, S., and Li, G. Systemic recruitment of osteoblastic cells in fracture healing. J Orthop Res 23, 1013, 2005.
16. Bertolini, F., and Pruneri, G. Chimerism of the transplanted heart. N Engl J Med 346, 1410, 2002.
17. Khosla, S., and Eghbali-Fatourechi, G.Z. Circulating cells with osteogenic potential. Ann N Y Acad Sci 1068, 489, 2006.
18. Kumagai, K., Vasanji, A., Drazba, J.A., Butler, R.S., and Muschler, G.F. Circulating cells with osteogenic potential are physiologically mobilized into the fracture healing site in the parabiotic mice model. J Orthop Res 26, 165, 2007.
19. Peng, H., Usas, A., Olshanski, A., Ho, A.M., Gearhart, B., Cooper, G.M., and Huard, J. VEGF improves, whereas sFlt1 inhibits, BMP2-induced bone formation and bone healing through modulation of angiogenesis. J Bone Miner Res 20, 2017, 2005.
20. Badillo, A.T., Zhang, L., and Liechty, K.W. Stromal progenitor cells promote leukocyte migration through production of stromal-derived growth factor 1 alpha: a potential mechanism for stromal progenitor cell-mediated enhancement of cellular recruitment to wounds. J Pediatr Surg 43, 1128, 2008.
21. Chen, L., Tredget, E.E., Wu, P.Y., and Wu, Y. Paracrine factors of mesenchymal stem cells recruit macrophages and endothelial lineage cells and enhance wound healing. PLoS ONE 3, e1886, 2008.
22. Goshima, J., Goldberg, V.M., and Caplan, A.I. The origin of bone formed in composite grafts of porous calcium phosphate ceramic loaded with marrow cells. Clin Orthop Relat Res 269, 274, 1991.
23. Kon, E., Muraglia, A., Corsi, A., Bianco, P., Marcacci, M., Martin, I., Boyde, A., Ruspantini, I., Chistolini, P., Rocca, M., Giardino, R., Cancedda, R., and Quarto, R. Autologous bone marrow stromal cells loaded onto porous hydroxyapatite ceramic accelerate bone repair in critical-size defects of sheep long bones. J Biomed Mater Res 49, 328, 2000.
24. Oliveira, S.M., Mijares, D.Q., Turner, G., Amaral, I.F., Barbosa, M.A., and Teixeira, C.C. Engineering endochondral bone: in vivo studies. Tissue Eng Part A 2008 Aug 31. [Epub ahead of print],
25. Augello, A., Tasso, R., Negrini, S.M., Amateis, A., Indiveri, F., Cancedda, R., and Pennesi, G. Bone marrow mesenchymal progenitor cells inhibit lymphocyte proliferation by activation of the programmed death 1 pathway. Eur J Immunol 35, 1482, 2005.
26. Augello, A., Tasso, R., Negrini, S.M., Cancedda, R., and Pennesi, G. Cell therapy using allogenic bone marrow mesenchymal stem cells prevents tissue damage in collagen-induced arthritis. Arthritis Rheum 56, 1175, 2007.
27. Le Blanc, K., Tammik, C., Rosendahl, K., Zetterberg, E., and Ringden, O. HLA expression and immunologic properties of differentiated and undifferentiated mesenchymal stem cells. Exp Hematol 31, 890, 2003.
28. De Kok, I.J., Peter, S.J., Archambault, M., van den Bos, C., Kadiyala, S., Aukhil, I., and Cooper, L.F. Investigation of allogenic mesenchymal stem cell-based alveolar bone formation: preliminary findings. Clin Oral Implants Res 14, 481, 2003.