Catabolism of flocculosin, an antimicrobial metabolite produced by Pseudozyma flocculosa

Glycobiology

Volumn 19, Issue 9, 2009, Pages 995-1001

  Mimee, Benjamin ^a   Labbé, Caroline ^a   Bélanger, Richard R ^a  

^a UNIVERSITÉ LAVAL   (Canada)

Author keywords

Cellobiose lipid; Enzymatic degradation; Flocculosin; Glycolipid; Pseudozyma flocculosa

Indexed keywords

3,15 DIHYDROXY HEXADECYL CELLOBIOSIDE; CELLOBIOSE; FLOCCULOSIN; GLYCOLIPID; UNCLASSIFIED DRUG;

ACIDITY; ACYLATION; ARTICLE; CONTROLLED STUDY; DEACYLATION; ECOLOGICAL NICHE; ENZYME DEGRADATION; FUNGUS; LIPID DEGRADATION; LIPOLYSIS; MASS SPECTROMETRY; NONHUMAN; PRIORITY JOURNAL; PROTEIN PURIFICATION; PSEUDOZYMA FLOCCULOSA; TEMPERATURE;

BASIDIOMYCOTA; CELLOBIOSE; GLYCOLIPIDS; HYDROGEN-ION CONCENTRATION; MASS SPECTROMETRY;

FUNGI; PSEUDOZYMA FLOCCULOSA;

EID: 68749088559     PISSN: 09596658     EISSN: 14602423     Source Type: Journal    
DOI: 10.1093/glycob/cwp078     Document Type: Article

References (21)

1. Avis TJ, Bélanger RR. 2002. Mechanisms and means of detection of biocontrol activity of Pseudozyma yeasts against plant-pathogenic fungi. FEMS Yeasts Res. 2:5-8.
2. Begerow D, Bauer R, Boekhout T. 2000. Phylogenetic placements of ustilaginomycetous anamorphs as deduced from nuclear LSU rDNA sequences. Mycol Res. 104:53-60.
3. Bélanger RR, Deacon JW. 1996. Interaction specificity of the biocontrol agent Sporothrix flocculosa: A video microscopy study. Phytopathology. 86:1317-1323.
4. Cheng Y, McNally DJ, Labbé C, Voyer N, Belzile F, Bélanger RR. 2003. Insertional mutagenesis of a fungal biocontrol agent led to discovery of a rare cellobiose lipid with antifungal activity. Appl Environ Microbiol. 69:2595-2602.
5. Clément-Mathieu G, Chain F, Marchand G, Bélanger RR. 2008. Leaf and powdery mildew colonization by glycolipid producing Pseudozyma species. Fungal Ecol. 1:69-77.
6. Eveleigh DE, Dateo GP, Reese ET. 1964. Fungal metabolism of complex glycosides: Ustilagic acid. J Biol Chem. 239:839-844.
7. Fakas S, Galiotou-Panayotou M, Papanikolaou S, Komaitis M, Aggelis G. 2007. Compositional shifts in lipid fractions during lipid turnover in Cunninghamella echinulata. Enzyme Microb Technol. 40:1321-1327.
8. Golubev WI. 2006. Antagonistic interactions among yeasts. In: Rosa CA, Péter G, editors. Biodiversity and Ecophysiology of Yeasts. Berlin (Germany): Springer. p. 197-219.
9. Hammami W, Labbé C, Chain F, Mimee B, Bélanger RR. 2008. Nutritional regulation and kinetics of flocculosin synthesis by Pseudozyma flocculosa. Appl Microbiol Biotechnol. 80:307-315.
10. Haskins RH. 1950. Biochemistry of the Ustilaginales: I. Preliminary cultural studies of Ustilago zeae. Can J Res. C 28:213-223.
11. Hewald S, Josephs K, Bölker M. 2005. Genetic analysis of biosurfactant production in Ustilago maydis. Appl Environ Microbiol 71:3033-3040.
12. Jarvis WR, Traquair JA, Bélanger RR. 2007. Perspectives on the development of Sporodex®: Fungal biocontrol for powdery mildew in greenhouse crops. In: Vincent C, Goettel MS, Lazarovits G, editors. Biological Control: A Global Perspective. Wallingford (UK): CABI Publishing. p. 224-233.
13. Lang S, Katsiwela E, Wagner F. 1989. Antimicrobial effects of biosurfactants. Fat Sci Technol. 91:363-366.
14. Mimee B, Labbé C, Pelletier R, Bélanger RR. 2005. Antifungal activity of flocculosin, a novel glycolipid isolated from Pseudozyma flocculosa. Antimicrob Agents Chemother. 49:1597-1599.
15. Mimee B, Pelletier R, Bélanger RR. 2009. In vitro antibacterial activity and antifungal mode of action of flocculosin, a membrane-active cellobiose lipid. J Appl Microbiol. doi:10.1111/ j.1365-2672.2009.04280.x.
16. Paulitz TC, Bélanger RR. 2001. Biological control in greenhouse systems. Annu Rev Phytopathol. 39:103-133.
17. Saha BC, Freer SN, Bothast RJ. 1994. Production, purification, and properties of a thermostable β-glucosidase from a color variant strain of Aureobasidium pullulans. Appl Environ Microbiol. 60:3774-3780.
18. Saul R, Chambers JP, Molyneux RJ, Elbein A. 1983. Castanospermine, a tetrahydroxylated alkaloid that inhibits β-glucosidase and β-glucocerebrosidase. Arch Biochem Biophys. 221:593-597.
19. Spoeckner S, Wray V, Nimtz M, Lang S. 1999. Glycolipids of the smut fungus Ustilago maydis from cultivation on renewable resources. Appl Microbiol Biotechnol. 51:33-39.
20. Teichmann B, Linne U, Hewald S, Marahiel MA, Bölker M. 2007. A biosynthetic gene cluster for a secreted cellobiose lipid with antifungal activity from Ustilago maydis. Mol Microbiol. 66:525-533.
21. Wagner A, Daum G. 2005. Formation and mobilization of neutral lipids in the yeast Saccharomyces cerevisiae. Biochem Soc Trans. 33:1174-1177.