Substantially reduced expression of PIAS1 is associated with colon cancer development

Journal of Cancer Research and Clinical Oncology

Volumn 135, Issue 9, 2009, Pages 1287-1291

  Coppola, Domenico ^a   Parikh, Vevek ^b   Boulware, David ^a,b   Blanck, George ^a,b  

^a H LEE MOFFITT CANCER CENTER AND RESEARCH INSTITUTE   (United States)

^b UNIVERSITY OF SOUTH FLORIDA   (United States)

Author keywords

Adenoma; Colon cancer; Interferon gamma; IRF 1; PIAS1; STAT1 ; Tissue microarray

Indexed keywords

GAMMA INTERFERON; INTERFERON REGULATORY FACTOR 1; PROTEIN INHIBITOR OF ACTIVATED STAT; PROTEIN INHIBITOR OF ACTIVATED STAT 1; STAT1 ALPHA PROTEIN; STAT1 PROTEIN; UNCLASSIFIED DRUG;

ADULT; AGED; ARTICLE; CLINICAL ASSESSMENT; COLON ADENOMA; COLON CANCER; CONTROLLED STUDY; CORRELATIONAL STUDY; DISEASE COURSE; FEMALE; HUMAN; HUMAN CELL; HUMAN TISSUE; MALE; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEIN FAMILY; STAINING; TISSUE MICROARRAY;

ADULT; AGED; AGED, 80 AND OVER; COLONIC NEOPLASMS; DISEASE PROGRESSION; DOWN-REGULATION; FEMALE; HUMANS; IMMUNOHISTOCHEMISTRY; INTERFERON REGULATORY FACTOR-1; MALE; MIDDLE AGED; PROTEIN INHIBITORS OF ACTIVATED STAT; SMALL UBIQUITIN-RELATED MODIFIER PROTEINS; TISSUE ARRAY ANALYSIS;

EID: 68649104728     PISSN: 01715216     EISSN: None     Source Type: Journal    
DOI: 10.1007/s00432-009-0570-z     Document Type: Article

References (15)

1. KB Bouker TC Skaar RB Riggins DS Harburger DR Fernandez A Zwart 2005 Interferon regulatory factor-1 (IRF-1) exhibits tumor suppressor activities in breast cancer associated with caspase activation and induction of apoptosis Carcinogenesis 26 1527 1535 10.1093/carcin/bgi113 (Pubitemid 41244519)
2. KM Detjen K Farwig M Welzel B Wiedenmann S Rosewicz 2001 Interferon gamma inhibits growth of human pancreatic carcinoma cells via caspase-1 dependent induction of apoptosis Gut 49 251 262 10.1136/gut.49.2.251 (Pubitemid 32675120)
3. DD Eason G Blanck 2001 High level class II trans-activator induction does not occur with transient activation of the IFN-gamma signaling pathway J Immunol 166 1041 1048
4. Guo W, Romano J (2007) A generalized Sidak-Holm procedure and control of generalized error rates under independence. Stat Appl Genet Mol Biol 6: (article 3)
5. L Klampfer J Huang LA Swaby L Augenlicht 2004 Requirement of histone deacetylase activity for signaling by STAT1 J Biol Chem 279 30358 30368
6. JK Lowney LD Boucher PE Swanson GM Doherty 1999 Interferon regulatory factor-1 and -2 expression in human melanoma specimens Ann Surg Oncol 6 604 608 10.1007/s10434-999-0604-4 (Pubitemid 29428802)
7. XM Luo AC Ross 2005 Physiological and receptor-selective retinoids modulate interferon gamma signaling by increasing the expression, nuclear localization, and functional activity of interferon regulatory factor-1 J Biol Chem 280 36228 36236 10.1074/jbc.M505749200 (Pubitemid 41633895)
8. XM Luo AC Ross 2005 Physiological and receptor-selective retinoids modulate interferon gamma signaling by increasing the expression, nuclear localization, and functional activity of interferon regulatory factor-1 J Biol Chem 280 36228 36236 10.1074/jbc.M505749200 (Pubitemid 41633895)
9. JJ Palvimo 2007 PIAS proteins as regulators of small ubiquitin-related modifier (SUMO) modifications and transcription Biochem Soc Trans 35 1405 1408 10.1042/BST0351405
10. C Ruiz-Ruiz C Ruiz de Almodovar A Rodriguez G Ortiz-Ferron JM Redondo A Lopez-Rivas 2004 The up-regulation of human caspase-8 by interferon-gamma in breast tumor cells requires the induction and action of the transcription factor interferon regulatory factor-1 J Biol Chem 279 19712 19720 10.1074/jbc. M313023200 (Pubitemid 38623409)
11. C Schindler DE Levy T Decker 2007 JAK-STAT signaling: from interferons to cytokines J Biol Chem 282 20059 20063 10.1074/jbc.R700016200 (Pubitemid 47099977)
12. M Stempelj M Kedinger L Augenlicht L Klampfer 2007 Essential role of the JAK/STAT1 signaling pathway in the expression of inducible nitric-oxide synthase in intestinal epithelial cells and its regulation by butyrate J Biol Chem 282 9797 9804 10.1074/jbc.M609426200
13. T Tamura S Ueda M Yoshida M Matsuzaki H Mohri T Okubo 1996 Interferon-gamma induces Ice gene expression and enhances cellular susceptibility to apoptosis in the U937 leukemia cell line Biochem Biophys Res Commun 229 21 26 10.1006/bbrc.1996.1752 (Pubitemid 27013704)
14. H Xi D Eason D Ghosh S Dovhey K Wright G Blanck 1999 Co-occupancy of the interferon regulatory element of the class II transactivator (CIITA) Type IV promoter by interferon regulatory factors 1 and 2 Oncogene 18 5889 5903 10.1038/sj.onc.1202969 (Pubitemid 29520445)
15. L Yu-Lee 2001 Stimulation of interferon regulatory factor-1 by prolactin Lupus 10 691 699 10.1191/096120301717164921 (Pubitemid 33041661)