HLA-haploidentical blood and bone marrow transplantation with anti-thymocyte globulin: Long-term comparison with HLA-identical sibling transplantation

Blood Cells, Molecules, and Diseases

Volumn 43, Issue 1, 2009, Pages 98-104

  Chen, Xing Hua ^a   Gao, Lei ^a   Zhang, Xi ^a   Gao, Li ^a   Zhang, Cheng ^a   Kong, Pei Yan ^a   Liu, Hong ^a   Peng, Xian Gui ^a   Sun, Ai Hua ^a   Qi, De guang ^a   Gong, Yi ^a   Wang, Qing Yu ^a  

^a THIRD MILITARY MEDICAL UNIVERSITY   (China)

Author keywords

Antithymocyte globulin; Haploidentical; Human leukocyte antigen; Identical; Stem cell transplantation

Indexed keywords

ACICLOVIR; BUSULFAN; COTRIMOXAZOLE; CYCLOPHOSPHAMIDE; CYCLOSPORIN A; CYTARABINE; FLUCONAZOLE; FOSCARNET; GANCICLOVIR; HLA ANTIGEN; LOMUSTINE; METHOTREXATE; MYCOPHENOLIC ACID 2 MORPHOLINOETHYL ESTER; NORFLOXACIN; RECOMBINANT GRANULOCYTE COLONY STIMULATING FACTOR; THYMOCYTE ANTIBODY;

ACUTE GRANULOCYTIC LEUKEMIA; ACUTE LYMPHOBLASTIC LEUKEMIA; ADOLESCENT; ADULT; ARTICLE; CANCER STAGING; CHILD; CHRONIC MYELOID LEUKEMIA; COMPARATIVE STUDY; CONTROLLED STUDY; CYTOMEGALOVIRUS INFECTION; DISEASE FREE SURVIVAL; DRUG DOSE INCREASE; DRUG DOSE REDUCTION; ENGRAFTMENT; FEMALE; GRAFT VERSUS HOST REACTION; HEMATOPOIETIC STEM CELL TRANSPLANTATION; HLA MATCHING; HUMAN; IMMUNOSUPPRESSIVE TREATMENT; INFECTION; LEUKEMIA RELAPSE; LONG TERM CARE; MAJOR CLINICAL STUDY; MALE; MORTALITY; OUTCOME ASSESSMENT; PNEUMOCYSTOSIS; PRIORITY JOURNAL; RELATIVE; SIBLING; STEM CELL MOBILIZATION; TREATMENT FAILURE;

ADOLESCENT; ADULT; ANTILYMPHOCYTE SERUM; CHILD; CHILD, PRESCHOOL; COHORT STUDIES; FEMALE; GRAFT VS HOST DISEASE; HEMATOPOIETIC STEM CELL TRANSPLANTATION; HLA ANTIGENS; HUMANS; LEUKEMIA; MALE; MIDDLE AGED; RECURRENCE; SIBLINGS; SURVIVAL ANALYSIS; TRANSPLANTATION CONDITIONING; YOUNG ADULT;

ARA;

EID: 68649104465     PISSN: 10799796     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.bcmd.2009.02.005     Document Type: Article

References (39)

1. Schipper R.F., D'Amaro J., Bakker J.T., Bakker J., van-Rood J.J., and Oudshoom M. HLA gene haplotype frequencies in bone marrow donors worldwide registries. Hum. Immunol. 52 (1997) 54-71
2. Koh L.P., and Chao N.J. Nonmyeloablative allogeneic hematopoietic stem cell transplant using haploidentical/haploidentical donors: a review. Blood Cells Mol. Dis. 40 (2008) 20-24
3. Beatty P.G., Mori M., and Milford E. Impact of racial genetic polymorphism on the probability of finding an HLA-matched donor. Transplantation 60 (1995) 778-783
4. Hansen J.A., Petersdorf E., Martin P.J., and Anasetti C. Hematopoietic stem cell transplants from unrelated donors. Immunol. Rev. 157 (1997) 141-151
5. Gluckman E., Rocha V., and Chevret S. Results of unrelated umbilical cord blood hematopoietic stem cell transplantation. Rev. Clin. Exp. Hematol. 5 (2001) 87-99
6. Sanz M.A., and Sanz G.F. Unrelated donor umbelical cord blood transplantation in adults. Leukemia 16 (2002) 1984-1991
7. Ogawa H., Ikegame K., Kaida K., Yoshihara S., Fujioka T., Taniguchi Y., et al. Unmanipulated HLA 2-3 antigen-haploidentical (haploidentical) bone marrow transplantation using only pharmacological GvHD prophylaxis. Exp. Hematol. 36 (2008) 1-8
8. Aversa F., Reisner Y., and Martelli M.F. The haploidentical option for high-risk haematological malignancies. Blood Cells Mol. Dis. 40 (2008) 8-12
9. Klingebiel T., Lang P., Schumm M., Koehl U., Basder P., Schwabe D., et al. Experiences with haploidentical stem cell transplantation in children with acute lymphoblastic leukemia. Pathol. Biol. 53 (2005) 159-161
10. Aversa F., Terenzi A., Tabilio A., Falzetti F., Carotti A., Ballanti S., et al. Full haplotype-mismatched hematopoietic stem-cell transplantation: a phase II study in patients with acute leukemia at high risk of relapse. J. Clin. Oncol. 23 (2005) 3447-3454
11. Charlson M.E., Pompei P., Ales K.L., and MacKenzie C.R. A new method of classifying prognostic comorbidity in longitudinal studies: development and validation. J. Chronic Dis. 40 (1987) 373-383
12. Sorror M.L., Maris M.B., Storer B., Sandmaier B.M., Diaconescu R., Flowers C., et al. Comparing morbidity and mortality of HLA-matched unrelated donor hematopoietic cell transplantation after nonmyeloablative and myeloablative conditioning: influence of pretransplantation comorbidities. Blood 104 (2004) 961-968
13. Thomas E.D., Storb R., Clift R.A., Fefer A., Johnson F.L., Neiman P.E., et al. Bone marrow transplantation. N. Engl. J. Med. 292 (1975) 895-902
14. Sulliven K.M., Agura E., Anasetti C., Appelbaum F., Badger C., Bearman S., et al. Chronic graft-versus-host disease and other late complications of bone marrow transplantation. Semin. Hematol. 28 (1991) 250-259
15. Shulman H.M., Sullivan K.M., Weiden P.L., McDonald G.B., Striker G.E., Sale G.E., et al. Chronic graft-versus-host syndrome in man. a long-term clinicopathologic study of 20 Seattle patients. Am. J. Med. 69 (1980) 204-217
16. Zaia J.A. Cytomegalovirus infection. In: Blume K.G., Forman S.J., and Appelbaum F.R. (Eds). Hematopoitic Cell Transplantation. 3rd ed. (2004), Blackwell Publishing, Malden, MA 701-726
17. Gooley T.A., Leisenring W., Crowley J., and Storer B.E. Estimation of failure probabilities in the presence of competing risks: new representations of old estimators. Statistics Med. 18 (1999) 695-706
18. Rizzieri D.A., Koh L.P., Long G.D., Gasparetto C., Sullivan K.M., Horwitz M., et al. Partially matched, nonmyeloablative allogeneic transplantation: clinical outcomes and immune reconstitution. J. Clin. Oncol. 25 (2007) 690-697
19. Barfield R.C., Otto M., Houston J., Holladay M., Geiger T., Martin J., et al. A one-step large-scale method for T- and B-cell depletion of mobilized PBSC for allogeneic transplantation. Cytotherapy 6 (2004) 1-6
20. O'Donnell P.V., Luznik L., Jones R.J., Vogelsang G.B., Leffell M.S., Phelps M., et al. Nonmyeloablative bone marrow transplantation from partially HLA-haploidentical related donors using posttransplantation cyclophosphamide. Biol. Blood Marrow Transplant. 8 (2002) 377-386
21. Ogawa H., Ikegame K., and Yoshihara S. Unmanipulated HLA 2-3 antigen mismatched (haploidentical) stem cell transplantation using nonmyeloablative conditioning. Biol. Blood Marrow Transplant. 12 (2006) 1073-1084
22. Kanda Y., Oshima K., Asano-Mori Y., Kandabashi K., Nakagawa M., Sakata-Yanagimoto M., et al. In vivo alemtuzumab enables haploidentical human leukocyte antigen-haploidentical hematopoietic stemcell transplantation without ex vivo graft manipulation. Transplantation 79 (2005) 1351-1357
23. + selected progenitor cells from alternative donors. Br. J. Haematol. 124 (2004) 72-79
24. Reddy V., Hill G.R., Pan L., Gerbitz A., Teshima T., Brinson Y., et al. G-CSF modulates cytokine profile of dendritic cells and decreases acute graft-versus-host disease through effects on the donor rather than the recipient. Transplantation 69 (2000) 691-693
25. Pan L., Delmonte Jr. J., Jalonen C.K., and Ferrara J.L. Pretreatment of donor mice with granulocyte-colony stimulating factor polarizes donor T lymphocytes toward type-2 cytokine production and reduces severity of experimental graft-versus-host disease. Blood 86 (1995) 4422-4429
26. Arpinati M., Green C.L., Heimfeld S., Heuser J.E., and Anasetti C. Granulocyte-colony stimulating factor mobilizes T helper 2-inducing dendritic cells. Blood 95 (2000) 2484-2490
27. Pereira R.F., Halford K.W., O'Hara M.D., Leeper D.B., Sokolov B.P., Pollard M.D., et al. Cultured adherent cells from marrow can serve as long-lasting precursor cells for bone, cartilage,and lung in irradiated mice. Proc. Natl. Acad. Sci. U. S. A. 92 (1995) 4857-4861
28. Jiang X.X., Zhang Y., Liu B., Zhang S.X., Wu Y., Yu X.D., et al. Human mesenchymal stem cells inhibit differentiation and function of monocyte-derived dendritic cells. Blood 105 (2005) 4120-4126
29. Maitra B., Szekely E., Gjini K., Laughlin M.J., Dennis J., Haynesworth S.E., et al. Human mesenchymal stem cells support unrelated donor hematopoietic stem cells and suppress T-cell activation. Bone Marrow Transpl. 33 (2004) 597-604
30. Bunn D., Lea C., Bevan D., Higgins R.M., and Hendry B.M. The pharmacokinetics of anti-thymocyte globulin (ATG) following intravenous infusion in man. Clin. Nephrol. 45 (1996) 29-32
31. Waller E.K., Langston A.A., Lonial S., Cherry J., Somani J., Allen A.J., et al. Pharmacokinetics and pharmacodynamics of antithymocyte globulin in recipients of partially HLA matched blood hematopoietic progenitor cell transplantation. Biol. Blood Marrow Transplant. 9 (2003) 460-471
32. Duggan P., Booth K., Chaudhry A., Stewart D., Ruether J.D., Gluck S., et al. Unrelated donor BMT recipients given pretransplant low-dose antithymocyte globulin have outcomes equivalent to matched sibling BMT: a matched pair analysis. Bone Marrow Transpl. 30 (2002) 681-686
33. Basara N., Baurmann H., Kolbe K., Yaman A., Labopin M., Burchardt A., et al. Antithymocyte globulin for the prevention of graft-versushost disease after unrelated hematopoietic stem cell transplantation for acute myeloid leukemia: results from the multicenter German cooperative study group. Bone Marrow Transpl. 35 (2005) 1011-1018
34. Mohr B., Koch R., Thiede C., Kroschinsky F., Ehninger G., and Bornhauser M. CD34+ cell dose, conditioning regimen and prior chemotherapy: factors with significant impact on the early kinetics of donor chimerism after allogeneic hematopoietic cell transplantation. Bone Marrow Transpl. 34 (2004) 949-954
35. Bacigalupo A. Antilymphocyte/thymocyte globulin for graft versus host disease prophylaxis: efficacy and side effects. Bone Marrow Transpl. 35 (2005) 225-231
36. van Rood J.J., Loberiza Jr. F.R., Zhang M.J., Oudshooom M., Class F., Cairo M.S., et al. Effect of tolerance to noninherited maternal antigens on the occurrence of graft-versus host disease after bone marrow transplantation from a parent or an HLA-haploidentical sibling. Blood 99 (2002) 1572-1577
37. Huang X.J. Current status of haploidentical stem cell transplantation for leukemia. J. Hemato. Oncol. 1 (2008) 27
38. Feuchtinger T., Lang P., Hamprecht K., Schumm M., Greil J., Jahn G., et al. Isolation and expansion of human adenovirus-specific CD4+ and CD8+ T cells according to IFN-gamma secretion for adjuvant immunotherapy. Exp. Hematol. 32 (2004) 282-289
39. Lang P., Greil J., Bader P., Handgretinger R., Klingebiel T., Schumm M., et al. Long-term outcome after haploidentical stem cell transplantation in children. Blood Cells Mol. Dis. 33 (2004) 281-287