Biosynthesis and characterization of a novel genetically engineered polymer for targeted gene transfer to cancer cells

Journal of Controlled Release

Volumn 138, Issue 3, 2009, Pages 188-196

  Canine, Brenda F ^a   Wang, Yuhua ^a   Hatefi, Arash ^a  

^a WASHINGTON STATE UNIVERSITY   (United States)

Author keywords

Biomimetic vector; Biopolymer; Gene therapy; Genetically engineered polymer; Non viral vector

Indexed keywords

CANCER CELLS; CELL NUCLEUS; CELL VIABILITY; ENDONUCLEASES; ENDOSOMES; GENE THERAPY; GENETICALLY ENGINEERED POLYMER; GENETICALLY ENGINEERED POLYMERS; HISTIDINE RESIDUES; MULTI DOMAINS; NANO-SIZE PARTICLES; NON-VIRAL VECTOR; NUCLEAR LOCALIZATION SIGNAL; PH-RESPONSIVE; REPEATING UNIT; TARGET CELLS;

AMINES; AMINO ACIDS; BIOCHEMISTRY; BIODEGRADATION; BIOMIMETICS; BIOMOLECULES; FUNCTIONAL POLYMERS; GENE EXPRESSION; GENE TRANSFER; INTERNET; POLYMERS; TARGETS; TOXICITY; VECTORS;

CELL MEMBRANES;

ARGININE; BAFILOMYCIN; BIOPOLYMER; CHLOROQUINE; ENHANCED GREEN FLUORESCENT PROTEIN; EPIDERMAL GROWTH FACTOR RECEPTOR 2; HISTIDINE; NOCODAZOLE; PLASMID DNA;

ANIMAL CELL; ARTICLE; BIODEGRADABILITY; BIOSYNTHESIS; BREAST CANCER; CANCER CELL CULTURE; CANCER GENE THERAPY; CELL NUCLEUS; CELL VIABILITY; CONTROLLED STUDY; DNA TRANSFER; ENDOSOME; GENE EXPRESSION REGULATION; GENETIC ENGINEERING; HUMAN; HUMAN CELL; NONHUMAN; NONVIRAL GENE DELIVERY SYSTEM; NUCLEAR LOCALIZATION SIGNAL; OVARY CANCER; PARTICLE SIZE; PRIORITY JOURNAL; PROSTATE CANCER;

BIOPOLYMERS; BREAST NEOPLASMS; CELL LINE, TUMOR; CLONING, MOLECULAR; DNA; ESCHERICHIA COLI; FEMALE; GENE THERAPY; GENETIC ENGINEERING; HUMANS; MALE; OVARIAN NEOPLASMS; PROSTATIC NEOPLASMS; TRANSFECTION;

EID: 68549130593     PISSN: 01683659     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.jconrel.2009.04.017     Document Type: Article

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