Distribution of lag-1 alleles and sequence-based types among Legionella pneumophila serogroup 1 clinical and environmental isolates in the United States

Journal of Clinical Microbiology

Volumn 47, Issue 8, 2009, Pages 2525-2535

  Kozak, Natalia A ^a   Benson, Robert F ^a   Brown, Ellen ^a   Alexander, Nicole T ^a   Taylor Jr , Thomas H ^a   Shelton, Brian G ^b   Fields, Barry S ^a  

^a NATIONAL CENTER FOR IMMUNIZATION AND RESPIRATORY DISEASES   (United States)

^b PathCon Laboratories   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

EPITOPE; MONOCLONAL ANTIBODY;

ANTIGEN ANTIBODY REACTION; ARTICLE; BACTERIAL GENE; BACTERIAL VIRULENCE; CONTROLLED STUDY; GENE FREQUENCY; GENE SEQUENCE; GENOTYPE; LAG 1 GENE; LEGIONELLA PNEUMOPHILA; LEGIONNAIRE DISEASE; NONHUMAN; NUCLEOTIDE SEQUENCE; PRIORITY JOURNAL; SEROTYPING; UNITED STATES;

ACETYLTRANSFERASES; ALLELES; AMINO ACID SEQUENCE; ANTIBODIES, BACTERIAL; ANTIBODIES, MONOCLONAL; BACTERIAL PROTEINS; BACTERIAL TYPING TECHNIQUES; DNA, BACTERIAL; ENVIRONMENTAL MICROBIOLOGY; EPIDEMIOLOGY, MOLECULAR; GENE ORDER; GENOTYPE; HUMANS; LEGIONELLA PNEUMOPHILA; LEGIONNAIRES' DISEASE; MOLECULAR SEQUENCE DATA; PREVALENCE; SEQUENCE ALIGNMENT; SEQUENCE ANALYSIS, DNA; SEROTYPING; UNITED STATES;

LEGIONELLA PNEUMOPHILA SEROGROUP 1;

EID: 68549130543     PISSN: 00951137     EISSN: None     Source Type: Journal    
DOI: 10.1128/JCM.02410-08     Document Type: Article

References (41)

1. Bartram, J., Y. Chartier, J. V. Lee, K. Pond, and S. Surman-Lee (ed.). 2007. Legionella and the prevention of legionellosis. World Health Organization, Geneva, Switzerland.
2. Bernander, S., K. Jacobson, J. H. Helbig, P. C. Luck, and M. Lundholm. 2003. A hospital-associated outbreak of Legionnaires' disease caused by Legionella pneumophila serogroup 1 is characterized by stable genetic fingerprinting but variable monoclonal antibody patterns. J. Clin. Microbiol. 41:2503-2508.
3. Borchardt, J., J. H. Helbig, and P. C. Luck. 2008. Occurrence and distribution of sequence types among Legionella pneumophila strains isolated from patients in Germany: common features and differences to other regions of the world. Eur. J. Clin. Microbiol. Infect. Dis. 27:29-36.
4. Castellani Pastoris, M., M. McIntyre, and P. Goldoni. 1990. Legionella pneumophila serogroup 1 population in Italy by monoclonal subtyping. Epidemiol. Infect. 105:169-174.
5. Cianciotto, N. P., J. K. Stamos, and D. W. Kamp. 1995. Infectivity of Legionella pneumophila mip mutant for alveolar epithelial cells. Curr. Microbiol. 30:247-250.
6. Dournon, E., W. F. Bibb, P. Rajagopalan, N. Desplaces, and R. M. McKinney. 1988. Monoclonal antibody reactivity as a virulence marker for Legionella pneumophila serogroup 1 strains. J. Infect. Dis. 157:496-501.
7. Edwards, M. T., N. K. Fry, and T. G. Harrison. 2008. Clonal population structure of Legionella pneumophila inferred from allelic profiling. Microbiology 154:852-864.
8. Feil, E. J., B. C. Li, D. M. Aanensen, W. P. Hanage, and B. G. Spratt. 2004. eBURST: inferring patterns of evolutionary descent among clusters of related bacterial genotypes from multilocus sequence typing data. J. Bacteriol. 186:1518-1530.
9. Felsenstein, J. 1985. Confidence limits on phylogenies: an approach using the bootstrap. Evolution 39:783-791.
10. Fields, B. S., R. F. Benson, and R. E. Besser. 2002. Legionella and Legionnaires' disease: 25 years of investigation. Clin. Microbiol. Rev. 15:506-526.
11. Fields, B. S., and M. R. Moore. 2006. Control of legionellae in the environment: a guide to the US guidelines. ASHRAE Trans. 112:691-699.
12. Gaia, V., N. K. Fry, B. Afshar, P. C. Luck, H. Meugnier, J. Etienne, R. Peduzzi, and T. G. Harrison. 2005. Consensus sequence-based scheme for epidemiological typing of clinical and environmental isolates of Legionella pneumophila. J. Clin. Microbiol. 43:2047-2052.
13. Gaia, V., N. K. Fry, T. G. Harrison, and R. Peduzzi. 2003. Sequence-based typing of Legionella pneumophila serogroup 1 offers the potential for true portability in legionellosis outbreak investigation. J. Clin. Microbiol. 41:2932-2939.
14. Harrison, T. G., B. Afshar, N. Doshi, N. K. Fry, and J. V. Lee. 2009. Distribution of Legionella pneumophila serogroups, monoclonal antibody subgroups and DNA sequence types in recent clinical and environmental isolates from England and Wales (2000-2008). Eur. J. Clin. Microbiol. Infect. Dis. 28:781-791.
15. Harrison, T. G., N. Doshi, N. K. Fry, and C. A. Joseph. 2007. Comparison of clinical and environmental isolates of Legionella pneumophila obtained in the UK over 19 years. Clin. Microbiol. Infect. 13:78-85.
16. Harrison, T. G., N. K. Fry, B. Afshar, W. Bellamy, N. Doshi, and A. P. Underwood. 2005. Typing of Legionella pneumophila and its role in elucidating the epidemiology of Legionnaire's disease, p. 94-99. In N. P. Cianciotto, Y. A. Kwaik, P. H. Edelstein, B. S. Fields, D. F. Geary, T. G. Harrison, C. A. Joseph, R. M. Ratcliff, J. E. Stout, and M. S. Swanson (ed.), Legionella: state of the art 30 years after its recognition. ASM Press, Washington, DC.
17. Helbig, J. H., S. Bernander, M. Castellani Pastoris, J. Etienne, V. Gaia, S. Lauwers, D. Lindsay, P. C. Luck, T. Marques, S. Mentula, M. F. Peeters, C. Pelaz, M. Struelens, S. A. Uldum, G. Wewalka, and T. G. Harrison. 2002. Pan-European study on culture-proven Legionnaires' disease: distribution of Legionella pneumophila serogroups and monoclonal subgroups. Eur. J. Clin. Microbiol. Infect. Dis. 21:710-716.
18. Helbig, J. H., P. C. Luck, Y. A. Knirel, W. Witzleb, and U. Zahringer. 1995. Molecular characterization of a virulence-associated epitope on the lipopolysaccharide of Legionella pneumophila serogroup 1. Epidemiol. Infect. 115:71-78.
19. Hunter, P. R., and M. A. Gaston. 1988. Numerical index of the discriminatory ability of typing systems: an application of Simpson's index of diversity. J. Clin. Microbiol. 26:2465-2466.
20. Joly, J. R., R. M. McKinney, J. O. Tobin, W. F. Bibb, I. D. Watkins, and D. Ramsay. 1986. Development of a standardized subgrouping scheme for Legionella pneumophila serogroup 1 using monoclonal antibodies. J. Clin. Microbiol. 23:768-771.
21. Jukes, T. H., and C. R. Cantor. 1969. Evolution of protein molecules, p. 21-32. In H. N. Munro (ed.), Mammalian protein metabolism. Academic Press, New York, NY.
22. Kozak, N. A., R. F. Benson, E. Brown, B. G. Shelton, and B. S. Fields. 2008. Distribution of sequence-based types (SBT) and lag-1 alleles among Legionella pneumophila serogroup 1 clinical and environmental isolates collected in the United States, poster D-139. Abstr. 108th Gen. Meet. Am. Soc. Microbiol. ASM, Washington, DC.
23. Kozak, N. A., E. Brown, R. F. Benson, B. G. Shelton, and B. S. Fields. 2007. Presence of a lag-1 gene as a virulence marker for Legionella pneumophila serogroup 1 strains, poster D-144. Abstr. 107th Gen. Meet. Am. Soc. Microbiol. ASM, Washington, DC.
24. Kuchana, R., and S. A. Uldum. 2007. PCR method for detection of monoclonal subgroups of Legionella pneumophila serogroup 1, abstr. Or19, p. 39. 22nd Annu. Meet. Eur. Working Group Legionella Infect., Stockholm, Sweden.
25. Lück, P. C., T. Freier, C. Steudel, Y. A. Knirel, E. Luneberg, U. Zahringer, and J. H. Helbig. 2001. A point mutation in the active site of Legionella pneumophila O-acetyltransferase results in modified lipopolysaccharide but does not influence virulence. Int. J. Med. Microbiol. 291:345-352.
26. Lück, P. C., M. Schuppler, and J. H. Helbig. 2002. Changes in the lag-1 locus of Legionella pneumophila serogroup 1 strains result in different lipopolysaccharides recognized by monoclonal antibodies but do not influence virulence, p. 52-55. In R. Marre (ed.), Legionella. ASM Press, Washington, DC.
27. Lüneberg, E., N. Zetzmann, D. Alber, Y. A. Knirel, O. Kooistra, U. Zahringer, and M. Frosch. 2000. Cloning and functional characterization of a 30 kb gene locus required for lipopolysaccharide biosynthesis in Legionella pneumophila. Int. J. Med. Microbiol. 290:37-49.
28. Maiden, M. C. 2006. Multilocus sequence typing of bacteria. Annu. Rev. Microbiol. 60:561-588.
29. Para, M. F., and J. F. Plouffe. 1983. Production of monoclonal antibodies to Legionella pneumophila serogroups 1 and 6. J. Clin. Microbiol. 18:895-900.
30. Ratzow, S., V. Gaia, J. H. Helbig, N. K. Fry, and P. C. Luck. 2007. Addition of neuA, the gene encoding N-acylneuraminate cytidylyl transferase, increases the discriminatory ability of the consensus sequence-based scheme for typing Legionella pneumophila serogroup 1 strains. J. Clin. Microbiol. 45:1965-1968.
31. Saitou, N., and M. Nei. 1987. The neighbor-joining method: a new method for reconstructing phylogenetic trees. Mol. Biol. Evol. 4:406-425.
32. Sanden, G. N., P. K. Cassiday, and J. M. Barbaree. 1993. Rapid immunodot technique for identifying Bordetella pertussis. J. Clin. Microbiol. 31:170-172.
33. Stout, J. E., J. Joly, M. Para, J. Plouffe, C. Ciesielski, M. J. Blaser, and V. L. Yu. 1988. Comparison of molecular methods for subtyping patients and epidemiologically linked environmental isolates of Legionella pneumophila. J. Infect. Dis. 157:486-495.
34. Tamura, K., J. Dudley, M. Nei, and S. Kumar. 2007. MEGA4: Molecular Evolutionary Genetics Analysis (MEGA) software version 4.0. Mol. Biol. Evol. 24:1596-1599.
35. Thürmer, A., J. H. Helbig, E. Jacobs, and P. C. Luck. 2009. PCR-based 'serotyping' of Legionella pneumophila. J. Med. Microbiol. 58:588-595.
36. Tijet, N., P. Tang, M. Romilowych, C. Duncan, F. Jamieson, D. E. Low, and C. Guyard. 2008. Molecular evolution and epidemiology of clinical Legionella pneumophila serotype I (L. pneumophila serogroup 1) isolates from Ontario: a 30 years retrospective analysis using sequence based typing, abstr. C-290. Abstr. 108th Gen. Meet. Am. Soc. Microbiol. ASM, Washington, DC.
37. Vassileva, M., K. Torii, M. Oshimoto, A. Okamoto, N. Agata, K. Yamada, T. Hasegawa, and M. Ohta. 2006. Phylogenetic analysis of Bacillus cereus isolates from severe systemic infections using multilocus sequence typing scheme. Microbiol. Immunol. 50:743-749.
38. Watkins, I. D., J. O. Tobin, P. J. Dennis, W. Brown, R. Newnham, and J. B. Kurtz. 1985. Legionella pneumophila serogroup 1 subgrouping by monoclonal antibodies-an epidemiological tool. J. Hyg. (London) 95:211-216.
39. Yu, V. L., J. F. Plouffe, M. C. Pastoris, J. E. Stout, M. Schousboe, A. Widmer, J. Summersgill, T. File, C. M. Heath, D. L. Paterson, and A. Chereshsky. 2002. Distribution of Legionella species and serogroups isolated by culture in patients with sporadic community-acquired legionellosis: an international collaborative survey. J. Infect. Dis. 186:127-128.
40. Zähringer, U., Y. A. Knirel, B. Lindner, J. H. Helbig, A. Sonesson, R. Marre, and E. T. Rietschel. 1995. The lipopolysaccharide of Legionella pneumophila serogroup 1 (strain Philadelphia 1): chemical structure and biological significance. Prog. Clin. Biol. Res. 392:113-139.
41. Zou, C. H., Y. A. Knirel, J. H. Helbig, U. Zahringer, and C. S. Mintz. 1999. Molecular cloning and characterization of a locus responsible for O acetylation of the O polysaccharide of Legionella pneumophila serogroup 1 lipopolysaccharide. J. Bacteriol. 181:4137-4141.