Gene expression profiling detects gene amplification and differentiates tumor types in breast cancer

Cancer Research

Volumn 63, Issue 9, 2003, Pages 2194-2199

  Dressman, Marlene A ^a   Baras, Alex ^a   Malinowski, Rachel ^a   Alvis, Lisa B ^a   Kwon, Irene ^a   Walz, Thomas M ^b   Polymeropoulos, Mihael H ^a  

^a NOVARTIS PHARMA AG   (Switzerland)

^b NONE

Author keywords

[No Author keywords available]

Indexed keywords

CELL NUCLEUS RECEPTOR; GROWTH FACTOR RECEPTOR BOUND PROTEIN 7; MESSENGER RNA; PHENYLETHANOLAMINE N METHYLTRANSFERASE; PROTEASOME; PROTEIN; PROTEIN SUBUNIT; RIBOSOME PROTEIN; STEROIDOGENIC ACUTE REGULATORY PROTEIN; UNCLASSIFIED DRUG;

ARTICLE; BREAST BIOPSY; BREAST CANCER; CHROMOSOMAL LOCALIZATION; CHROMOSOME MAP; CONTROLLED STUDY; CORRELATION ANALYSIS; GENE; GENE AMPLIFICATION; GENE EXPRESSION; GENE EXPRESSION PROFILING; GENE MAPPING; HUMAN; HUMAN TISSUE; NUCLEOTIDE SEQUENCE; ONCOGENE NEU; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEIN LOCALIZATION; STEROIDOGENIC ACUTE REGULATORY PROTEIN RELATED GENE; TUMOR BIOPSY; TUMOR DIFFERENTIATION; VALIDATION PROCESS;

BREAST NEOPLASMS; CARRIER PROTEINS; CHROMOSOMES, HUMAN, PAIR 17; GENE AMPLIFICATION; GENE DOSAGE; GENE EXPRESSION PROFILING; GENE EXPRESSION REGULATION, NEOPLASTIC; GENES, ERBB-2; HUMANS; MEMBRANE PROTEINS; OLIGONUCLEOTIDE ARRAY SEQUENCE ANALYSIS; PHENYLETHANOLAMINE N-METHYLTRANSFERASE; RECEPTOR, ERBB-2; RECEPTORS, ESTROGEN;

EID: 0038404847     PISSN: 00085472     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

References (19)

1. Slamon, D. J., Clark, G. M., Wong, S. G., Levin, W. J., Ullrich, A., and McGuire, W. L. Human breast cancer: correlation of relapse and survival with amplification of the HER-2/neu oncogene. Science (Wash. DC), 235: 177-182, 1987.
2. Slamon, D. J., et al. Studies of the HER-2/neu proto-oncogene in human breast and ovarian cancer. Science (Wash. DC), 244: 707-712, 1989.
3. Borg, A., Tandon, A. K., Sigurdsson, H., Clark, G. M., Ferno, M., Fuqua, S. A., Killander, D., and McGuire, W. L. HER-2/neu amplification predicts poor survival in node-positive breast cancer. Cancer Res., 50: 4332-4337, 1990.
4. Ciocca, D. R., et al. Correlation of HER-2/neu amplification with expression and with other prognostic factors in 1103 breast cancers. J. Natl. Cancer Inst. (Bethesda), 84: 1279-1282, 1992.
5. Forozan, F., Mahlamäki, E. H., Monni, O., Chen, Y., Veldman, R., Jiang, Y., Gooden, G. C., Ethier, S. P., Kallioniemi, A., and Kallioniemi, O-P. Comparative genomic hybridization analysis of 38 breast cancer cell lines: a basis for interpreting complementary DNA microarray data. Cancer Res., 60: 4519-4525, 2000.
6. Muleris, M., Almeida, A., Gerbault-Seureau, M., Malfoy, B., and Dutrillaux, B. Detection of DNA amplification in 17 primary breast carcinomas with homogeneously staining regions by a modified comparative genomic hybridization technique. Genes Chromosomes Cancer, 10: 160-170, 1994.
7. Ried, T., Just, K. E., Holtgreve-Grez, H., du Manoir, S., Speicher, M. R., Schrock, E., Latham, C., Blegen, H., Zetterberg, A., and Cremer, T. Comparative genomic hybridization of formalin-fixed, paraffin-embedded breast tumors reveals different patterns of chromosomal gains and losses in fibroadenomas and diploid and aneuploid carcinomas. Cancer Res., 55: 5415-5423, 1995.
8. Barlund, M., Tirkkonen, M., Forozan, F., Tanner, M. M., Kallioniemi, O., and Kallioniemi, A. Increased copy number at 17q22-q24 by CGH in breast cancer is due to high-level amplification of two separate regions. Genes Chromosomes Cancer, 20: 372-376, 1997.
9. Sørlie, T., et al. Gene expression patterns of breast carcinomas distinguish tumor subclasses with clinical implications. Proc. Natl. Acad. Sci. USA, 98: 10869-10874, 2001.
10. Kauraniemi, P., Barlund, M., Monni, O., and Kallioniemi, A. New amplified and highly expressed genes discovered in the ERBB2 amplicon in breast cancer by cDNA microarrays. Cancer Res., 61: 8235-8240, 2001.
11. Perou, C. M., et al. Molecular portraits of human breast tumours. Nature (Lond.), 406: 747-752, 2000.
12. Hedenfalk, I., et al. Gene-expression profiles in hereditary breast cancer. N. Engl. J. Med., 8: 539-548, 2001.
13. Dressman, M. A., et al. Genes that co-cluster with estrogen receptor alpha in microarray analysis of breast biopsies. Pharmacogenomics J., 1: 135-141, 2001.
14. User Bulletin no. 2 ABI PRISM 7700 sequence detection system, pp. 11-31, 2001.
15. King, B. I., et al. Neu proto-oncogene amplification and expression in ovarian adenomacarcinoma cell lines. Am. J. Pathol., 140: 23-31, 1992.
16. Hartmann, L. C., et al. Prognostic value of c-erbB2 overexpression in axillary lymph node positive breast cancer. Results from a randomized adjuvant treatment protocol. Cancer (Phila.), 74: 2956-2963, 1994.
17. Vogel, C., et al. First-line, single-agent Herceptin(trastuzumab) in metastatic breast cancer: a preliminary report. Eur. J. Cancer, 37: (Suppl. 1): S25-S29, 2001.
18. Carter, P., et al. Humanization of an anti-p185HER2 antibody for human cancer therapy. Proc. Natl. Acad. Sci. USA, 89: 4285-4289, 1992.
19. Moog-Lutz, C., et al. MLN64 exhibits homology with the steroidogenic acute regulatory protein (STAR) and is over-expressed in human breast carcinomas. Int. J. Cancer, 71: 183-191, 1997.