Biochemical changes and cytotoxicity associated with methionine depletion in paediatric central nervous system tumour cell lines

Anticancer Research

Volumn 29, Issue 8, 2009, Pages 2971-2976

  Najim, N ^a   Podmore, I D ^a   Mcgown, A ^a   Estlin, Eddy J ^b  

^a UNIVERSITY OF SALFORD   (United Kingdom)

^b ROYAL MANCHESTER CHILDREN S HOSPITAL   (United Kingdom)

Author keywords

CNS tumour; Glutathione; Methionine depletion; Methionine synthase; MGMT

Indexed keywords

GLUTATHIONE; METHIONINE; METHIONINE SYNTHASE; METHYLATED DNA PROTEIN CYSTEINE METHYLTRANSFERASE; N METHYL N (TERT BUTYLDIMETHYLSILYL)TRIFLUOROACETAMIDE; PHTHALALDEHYDE; SULFORHODAMINE B; TRIFLUOROACETAMIDE DERIVATIVE; UNCLASSIFIED DRUG;

APOPTOSIS; ARTICLE; BIOCHEMISTRY; CELL CYCLE; CELL DEATH; CELL GROWTH; CELL LINE; CELL PROLIFERATION; CELL SURVIVAL; CENTRAL NERVOUS SYSTEM; CHEMOSENSITIVITY; CONTROLLED STUDY; CYTOTOXICITY; DERIVATIZATION; ENZYME ACTIVITY; GAS CHROMATOGRAPHY; GLIOMA; GROWTH INHIBITION; HIGH PERFORMANCE LIQUID CHROMATOGRAPHY; HUMAN; HUMAN CELL; IN VITRO STUDY; MASS SPECTROMETRY; MEDULLOBLASTOMA; PEDIATRICS; PRIORITY JOURNAL; PROTEIN DEPLETION; PROTEIN EXPRESSION; TUMOR CELL LINE;

APOPTOSIS; BRAIN NEOPLASMS; CELL CYCLE; CELL PROLIFERATION; CEREBELLAR NEOPLASMS; CHILD; DNA MODIFICATION METHYLASES; DNA REPAIR ENZYMES; GAS CHROMATOGRAPHY-MASS SPECTROMETRY; GLIOMA; GLUTATHIONE; HUMANS; MEDULLOBLASTOMA; METHIONINE; TUMOR CELLS, CULTURED; TUMOR STEM CELL ASSAY; TUMOR SUPPRESSOR PROTEINS;

EID: 68549117136     PISSN: 02507005     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

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