MtuA, a lipoprotein receptor antigen from Streptococcus uberis, is responsible for acquisition of manganese during growth in milk and is essential for infection of the lactating bovine mammary gland

Infection and Immunity

Volumn 71, Issue 9, 2003, Pages 4842-4849

  Smith, Amanda J ^a   Ward, Philip N ^a   Field, Terence R ^a   Jones, Catherine L ^a   Lincoln, Ruth A ^a   Leigh, James A ^a  

^a INSTITUTE FOR ANIMAL HEALTH   (United Kingdom)

Author keywords

[No Author keywords available]

Indexed keywords

ANTIGEN; LIPOPROTEIN RECEPTOR; MANGANESE; MANGANESE SULFATE; METAL ION; PROTEIN MTUA; UNCLASSIFIED DRUG;

ANIMAL EXPERIMENT; ARTICLE; BACTERIAL COLONIZATION; BACTERIAL GENE; BACTERIAL GROWTH; BACTERIUM ISOLATE; COLONY FORMING UNIT; CONTROLLED STUDY; FEMALE; GENE INSERTION; GENE SEQUENCE; GENETIC CODE; INFLAMMATION; LACTATION; MASTITIS; MILK; MTSA GENE; MUTAGENESIS; NONHUMAN; NUCLEOTIDE SEQUENCE; PRIORITY JOURNAL; PROTEIN FUNCTION; PSAA GENE; SEQUENCE HOMOLOGY; STREPTOCOCCUS PNEUMONIAE; STREPTOCOCCUS PYOGENES; STREPTOCOCCUS UBERIS;

ANIMALS; ANTIGENS, BACTERIAL; BASE SEQUENCE; CATTLE; DNA, BACTERIAL; FEMALE; GENES, BACTERIAL; LACTATION; MAMMARY GLANDS, ANIMAL; MANGANESE; MASTITIS, BOVINE; MILK; MOLECULAR SEQUENCE DATA; MUTAGENESIS, INSERTIONAL; RECEPTORS, LIPOPROTEIN; STREPTOCOCCUS; VIRULENCE;

EID: 0041322874     PISSN: 00199567     EISSN: None     Source Type: Journal    
DOI: 10.1128/IAI.71.9.4842-4849.2003     Document Type: Article

References (50)

1. Andersen, R. N., N. Ganeshkumar, and P. E. Kolenbrander. 1993. Cloning of the Streptococcus gordonii PK488 gene, encoding an adhesin which mediates coaggregation with Actinomyces naeslundii PK606. Infect. Immun. 61:981-987.
2. Arnold, C., and I. J. Hodgson. 1991. Vectorette PCR: a novel approach to genomic walking. PCR Methods Appl. 1:39-42.
3. Bartsevich, V. V., and H. B. Pakrasi. 1995. Molecular identification of an ABC transporter complex for manganese: analysis of a cyanobacterial mutant strain impaired in the photosynthetic oxygen evolution process. EMBO J. 14:1845-1853.
4. Berry, A. M., and J. C. Paton. 1996. Sequence heterogeneity of PsaA, a 37-kilodalton putative adhesin essential for virulence of Streptococcus pneumoniae. Infect. Immun. 64:5255-5262.
5. Briles, D. E., R. C. Tart, E. Swiatlo, J. P. Dillard, P. Smith, K. A. Benton, B. A. Ralph, A. Brooks-Walter, M. J. Crain, S. K. Hollingshead, and L. S. McDaniel. 1998. Pneumococcal diversity: considerations for new vaccine strategies with emphasis on pneumococcal surface protein A (PspA). Clin. Microbiol. Rev. 11:645-657.
6. Burnette-Curley, D., V. Wells, H. Viscount, C. L. Munro, J. C. Fenno, P. Fives-Taylor, and F. L. Macrina. 1995. FimA, a major virulence factor associated with Streptococcus parasanguis endocarditis. Infect. Immun. 63:4669-4674.
7. Dintilhac, A., G. Alloing, C. Granadel, and J. P. Claverys. 1997. Competence and virulence of Streptococcus pneumoniae: Adc and PsaA mutants exhibit a requirement for Zn and Mn resulting from inactivation of putative ABC metal permeases. Mol. Microbiol. 25:727-739.
8. Dintilhac, A., and J. P. Claverys. 1997. The adc locus, which affects competence for genetic transformation in Streptococcus pneumoniae, encodes an ABC transporter with a putative lipoprotein homologous to a family of streptococcal adhesins. Res. Microbiol. 148:119-131.
9. Dutt, K. W., R. J. Eberhart, and R. A. Wilson. 1986. In vitro growth of mastitis pathogens in mammary secretions of the dry and peripartum periods. J. Dairy Sci. 69:2408-2415.
10. Fenno, J. C., A. Shaikh, G. Spatafora, and P. Fives-Taylor. 1995. The fimA locus of Streptococcus parasanguis encodes an ATP-binding membrane transport system. Mol. Microbiol. 15:849-863.
11. Field, T. R., P. N. Ward, L. H. Pedersen, and J. A. Leigh. 2003. The hyaluronic acid capsule of Streptococcus uberis is not required for the development of infection and clinical mastitis. Infect. Immun. 71:132-139.
12. Finch, J. M., A. W. Hill, T. R. Field, and J. A. Leigh. 1994. Local vaccination with killed Streptococcus uberis protects the bovine mammary gland against experimental intramammary challenge with the homologous strain. Infect. Immun. 62:3599-3603.
13. Finch, J. M., A. Winter, A. W. Walton, and J. A. Leigh. 1997. Further studies on the efficacy of a live vaccine against mastitis caused by Streptococcus uberis. Vaccine 15:1138-1143.
14. Ganeshkumar, N., P. M. Hannam, P. E. Kolenbrander, and B. C. McBride. 1991. Nucleotide sequence of a gene coding for a saliva-binding protein (SsaB) from Streptococcus sanguis 12 and possible role of the protein in coaggregation with actinomyces. Infect. Immun. 59:1093-1099.
15. Guidry, A. J. 1985. Mastitis, p. 237-262. In B. L. Larson (ed.), Lactation. Iowa State University Press, Ames, Iowa.
16. Herald, C. T., J. R. Brunner, and S. T. Bass. 1957. A spectrographic analysis of two protein fractions of the fat-globule membrane of normal cow's milk. J. Dairy Sci. 40:446.
17. Hill, A. W., J. M. Finch, T. R. Field, and J. A. Leigh. 1994. Immune modification of the pathogenesis of Streptococcus uberis mastitis in the dairy cow. FEMS Immunol. Med. Microbiol. 8:109-117.
18. Hill, A. W., and J. A. Leigh. 1989. DNA fingerprinting of Streptococcus uberis: a useful tool for epidemiology of bovine mastitis. Epidemiol. Infect. 103:165-171.
19. Hillerton, J. E., M. F. Shearn, R. M. Teverson, S. Langridge, and J. M. Booth. 1993. Effect of pre-milking teat dipping on clinical mastitis on dairy farms in England. J. Dairy Res. 60:31-41.
20. Janulczyk, R., J. Pallon, and L. Bjorck. 1999. Identification and characterization of a Streptococcus pyogenes ABC transporter with multiple specificity for metal cations. Mol. Microbiol. 34:596-606.
21. Jenkinson, H. F. 1992. Adherence, coaggregation, and hydrophobicity of Streptococcus gordonii associated with expression of cell surface lipoproteins. Infect. Immun. 60:1225-1228.
22. Jenkinson, H. F. 1994. Cell surface protein receptors in oral streptococci. FEMS Microbiol. Lett. 121:133-140.
23. Johnsen, L. B., K. Poulsen, M. Kilian, and T. E. Petersen. 1999. Purification and cloning of a streptokinase from Streptococcus uberis. Infect. Immun. 67:1072-1078.
24. Kitten, T., C. L. Munro, S. M. Michalek, and F. L. Macrina. 2000. Genetic characterization of a Streptococcus mutans LraI family operon and role in virulence. Infect. Immun. 68:4441-4451.
25. 2+ uptake. J. Bacteriol. 180:290-295.
26. Kolenbrander, P. E., R. N. Andersen, and N. Ganeshkumar. 1994. Nucleotide sequence of the Streptococcus gordonii PK488 coaggregation adhesin gene, scaA, and ATP-binding cassette. Infect. Immun. 62:4469-4480.
27. Kossaibati, M. A., and R. J. Esslemont. 1997. The costs of production diseases in dairy herds in England. Vet. J. 154:41-51.
28. Lawrence, M. C., P. A. Pilling, V. C. Epa, A. M. Berry, A. D. Ogunniyi, and J. C. Paton. 1998. The crystal structure of pneumococcal surface antigen PsaA reveals a metal-binding site and a novel structure for a putative ABC-type binding protein. Structure 6:1553-1561.
29. Leigh, J. A. 1994. Purification of a plasminogen activator from Streptococcus uberis. FEMS Microbiol. Lett. 118:153-158.
30. Leigh, J. A. 1999. Streptococcus uberis: a permanent barrier to the control of bovine mastitis? Vet. J. 157:225-238.
31. Leigh, J. A., and T. R. Field. 1994. Streptococcus uberis resists the bactericidal action of bovine neutrophils despite the presence of bound immunoglobulin. Infect. Immun. 62:1854-1859.
32. Leigh, J. A., J. M. Finch, T. R. Field, N. C. Real, A. Winter, A. W. Walton, and S. M. Hodgkinson. 1999. Vaccination with the plasminogen activator from Streptococcus uberis induces an inhibitory response and protects against experimental infection in the dairy cow. Vaccine 17:851-857.
33. Lincoln, R. A., and J. A. Leigh. 1998. Characterization of the interaction of bovine plasmin with Streptococcus uberis. J. Appl. Microbiol. 84:1104-1110.
34. Ling, E. R., S. K. Kon, and J. W. G. Porter. 1961. The composition of milk, p. 217-218. In S. K. Kon and A. T. Cowie (ed.), Milk: the mammary gland and its secretion, vol. 2. Academic Press, New York, N.Y.
35. Maguin, E., H. Prevost, S. D. Ehrlich, and A. Gruss. 1996. Efficient insertional mutagenesis in lactococci and other gram-positive bacteria. J. Bacteriol. 178:931-935.
36. McDonald, J. S., and A. J. Anderson. 1981. Experimental infection of bovine mammary glands with Streptococcus uberis during the nonlactating period. Am. J. Vet. Res. 42:465-467.
37. Oligino, L., and P. Fives-Taylor. 1993. Overexpression and purification of a fimbria-associated adhesin of Streptococcus parasanguis. Infect. Immun. 61:1016-1022.
38. Paape, M. J., W. P. Wergin, A. J. Guidry, and W. D. Schultze. 1981. Phagocytic defense of the ruminant mammary gland. Adv. Exp. Med. Biol. 137:555-578.
39. Persson, K., I. Larsson, and C. Hallen Sandgren. 1993. Effects of certain inflammatory mediators on bovine neutrophil migration in vivo and in vitro. Vet. Immunol. Immunopathol. 37:99-112.
40. Pilling, P. A., M. C. Lawrence, A. M. Berry, A. D. Ogunniyi, R. A. Lock, and J. C. Paton. 1998. Expression, purification and preliminary X-ray crystallographic analysis of PsaA, a putative metal-transporter protein of Streptococcus pneumoniae. Acta Crystallogr. D Biol. Crystallogr. 54:1464-1466.
41. Sampson, J. S., Z. Furlow, A. M. Whitney, D. Williams, R. Facklam, and G. M. Carlone. 1997. Limited diversity of Streptococcus pneumoniae psaA among pneumococcal vaccine serotypes. Infect. Immun. 65:1967-1971.
42. Smith, A. J., A. J. Kitt, P. N. Ward, and J. A. Leigh. 2002. Isolation and characterization of a mutant strain of Streptococcus uberis, which fails to utilize a plasmin derived beta-casein peptide for the acquisition of methionine. J. Appl. Microbiol. 93:631-639.
43. Supek, F., L. Supekova, H. Nelson, and N. Nelson. 1996. A yeast manganese transporter related to the macrophage protein involved in conferring resistance to mycobacteria. Proc. Natl. Acad. Sci. USA 93:5105-5110.
44. Talkington, D. F., B. G. Brown, J. A. Tharpe, A. Koenig, and H. Russell. 1996. Protection of mice against fatal pneumococcal challenge by immunization with pneumococcal surface adhesin A (PsaA). Microb. Pathog. 21:17-22.
45. Tam, R., and M. H. Saier. 1993. Structural, functional, and evolutionary relationships among extracellular solute-binding receptors of bacteria. Microbiol. Rev. 57:320-326.
46. Thomas, J. W. 1970. Metabolism of iron and manganese. J. Dairy Sci. 53:1107-1123.
47. Viscount, H. B., C. L. Munro, D. Burnette-Curley, D. L. Peterson, and F. L. Macrina. 1997. Immunization with FimA protects against Streptococcus parasanguis endocarditis in rats. Infect. Immun. 65:994-1002.
48. Ward, P. N., T. R. Field, W. G. Ditcham, E. Maguin, and J. A. Leigh. 2001. Identification and disruption of two discrete loci encoding hyaluronic acid capsule biosynthesis genes hasA, hasB, and hasC in Streptococcus uberis. Infect. Immun. 69:392-399.
49. Watts, J. L. 1988. Etiological agents of bovine mastitis. Vet. Microbiol. 16:41-66.
50. Yancey, R. J., Jr. 1999. Vaccines and diagnostic methods for bovine mastitis: fact and fiction. Adv. Vet. Med. 41:257-273.