Pediatric cardiopulmonary bypass circuits: A review of studies conducted at the Penn State pediatric cardiac research laboratories

Journal of Extra-Corporeal Technology

Volumn 41, Issue 1, 2009, Pages

  Miller, Akemi ^a   Lu, Chiajung Karen ^a   Wang, Shigang ^a   Umstead, Todd M ^a   Freeman, Willard M ^a   Vrana, Kent ^a   Yang, Sung ^a   Myers, John L ^b   Phelps, David S ^a   Zahn, Jeffrey D ^b   Ündar, Akif ^a,c  

^a Gwangju Institute of Science and Technology (GIST)   (South Korea)

^b RUTGERS UNIVERSITY   (United States)

^c PENN STATE CHILDREN S HOSPITAL   (United States)

Author keywords

Anti factor D monoclonal antibody; Microdevices for measuring systemic inflammation; Microemboli detection and classification; Plasma proteomics

Indexed keywords

COMPLEMENT COMPONENT C3A; COMPLEMENT COMPONENT C4A; COMPLEMENT COMPONENT C5A; COMPLEMENT FACTOR D; MONOCLONAL ANTIBODY;

BLOOD FILTER; BLOOD PUMP; BODY TEMPERATURE; CARDIOPULMONARY BYPASS; CONFERENCE PAPER; CRYOTHERAPY; FLOW RATE; HUMAN; MICROEMBOLISM; NEUTROPHIL; PATIENT MONITORING; PROTEOMICS; PULSATILE FLOW; SURGICAL DRAINAGE; THROMBOCYTE ACTIVATION; VACUUM; VACUUM ASSISTED VENOUS DRAINAGE; ADOLESCENT; AIR EMBOLISM; CHILD; EXTRACORPOREAL OXYGENATION; FEMALE; IMMUNOLOGY; INFANT; INFLAMMATION; INSTRUMENTATION; MALE; MEDICAL RESEARCH; OXIDATIVE STRESS; PERIOPERATIVE PERIOD; PRESCHOOL CHILD; REVIEW; UNITED STATES;

ADOLESCENT; ANTIBODIES, MONOCLONAL; BIOMEDICAL RESEARCH; CARDIOPULMONARY BYPASS; CHILD; CHILD, PRESCHOOL; COMPLEMENT FACTOR D; EMBOLISM, AIR; EXTRACORPOREAL MEMBRANE OXYGENATION; FEMALE; HUMANS; INFANT; INFLAMMATION; MALE; OXIDATIVE STRESS; PENNSYLVANIA; PERIOPERATIVE CARE; PROTEOMICS;

EID: 68549096179     PISSN: 00221058     EISSN: 29698960     Source Type: Journal    
DOI: None     Document Type: Conference Paper

References (11)

1. Ündar A, Ji B, Kunselman AR, Myers JL. Detection and classification of gaseous microemboli during pulsatile and nonpulsatile perfusion in a simulated neonatal CPB model. ASAIO J. 2007;53:725-9.
2. Schreiner RS, Rider AR, Myers JW, et al. Microemboli detection and classification by innovative ultrasound technology during simulated neonatal cardiopulmonary bypass at different flow rates, perfusion modes, and perfusate temperatures. ASAIO J. 2008;54:316-24.
3. Wang S, Kunselman AR, Myers JL, Ündar A. Comparison of two different blood pumps on delivery of gaseous microemboli during pulsatile and non-pulstaile perfusion in a simulated infant CPB model. ASAIO J. 2008;54:538-41.
4. Wang S, Baer L, Kunselman AR, Myers JL, Ündar A. Delivery of gaseous microemboli with vacuum-assisted venous drainage during pulsatile and nonpulsatile perfusion in a simulated neonatal cardiopulmonary bypass model. ASAIO J. 2008;54:416-22.
5. Wang S, Win KN, Kunselman AR, Woitas K, Myers JL, Ündar A. The capability of trapping gaseous microemboli of two pediatric arterial filters with pulsatile and non-pulsatile flow in a simulated infant CPB model. ASAIO J. 2008;54:519-22.
6. Wang S, Miller A, Myers JL, Ündar A. "Stolen" blood flow: The effect of an open arterial filter purge line in a simulated neonatal CPB model. ASAIO J. 2008;54:432-5.
7. Ündar A, Eichstaedt HC, Clubb FJ Jr, et al. Novel anti-factor D monoclonal antibody inhibits complement and leukocyte activation in a baboon model of cardiopulmonary bypass. Ann Thorac Surg. 2002;74:355-62.
8. Fung M, Loubser PG, Ündar A, et al. Inhibition of complement, neutrophil, and platelet activation by an anti-factor D monocolonal antibody in simulated cardiopulmonary bypass circuits. J Thorac Cardiovasc Surg. 2001;122:113-22.
9. Ündar A, Eichstaedt HC, Clubb FJ Jr, et al. Anesthetic induction with ketamine inhibits platelet activation before, during, and after cardiopulmonary bypass in baboons. Artif Organs. 2004;28:959-62.
10. Yang S, Ündar A, Zahn JD. Continuous cytometric bead processing within a microfluidic device for bead based sensing platforms. Lab Chip. 2007;7:588-95.
11. Lull ME, Carkaci-Salli N, Freeman WM, et al. Plasma biomarkers in pediatric patients undergoing cardiopulmonary bypass. Pediatr Res. 2008;63:638-44.