Maggot secretions suppress pro-inflammatory responses of human monocytes through elevation of cyclic AMP

Diabetologia

Volumn 52, Issue 9, 2009, Pages 1962-1970

  Van Der Plas, M J A ^a   Baldry, M ^a   Van Dissel, J T ^a   Jukema, G N ^b   Nibbering, P H ^a  

^a LEIDEN UNIVERSITY MEDICAL CENTER   (Netherlands)

^b VU UNIVERSITY MEDICAL CENTER   (Netherlands)

Author keywords

Chemokines; Chemotaxis; Chronic wounds; Cyclic AMP; Cytokines; Inflammation; Phagocytosis; Signal transduction

Indexed keywords

ANTIINFLAMMATORY AGENT; CHEMOKINE; CYCLIC AMP; CYTOKINE; INTERLEUKIN 10; INTERLEUKIN 12P40; INTERLEUKIN 8; LIPOPOLYSACCHARIDE; LIPOTEICHOIC ACID; MACROPHAGE INFLAMMATORY PROTEIN 1BETA; MACROPHAGE MIGRATION INHIBITION FACTOR; MONOCYTE CHEMOTACTIC PROTEIN 1; TUMOR NECROSIS FACTOR ALPHA;

ANTIBACTERIAL ACTIVITY; ARTICLE; CELL SURFACE; CELL VIABILITY; CHEMOTAXIS; CHRONIC WOUND; CONCENTRATION RESPONSE; CONTROLLED STUDY; CYTOKINE PRODUCTION; FLY; HUMAN; INFLAMMATION; LUCILIA SERICATA; MAGGOT; MAGGOT THERAPY; MONOCYTE; PHAGOCYTOSIS; PRIORITY JOURNAL; PROTEIN EXPRESSION; SECRETION; SIGNAL TRANSDUCTION; STAPHYLOCOCCUS AUREUS;

ANIMALS; CELL MOVEMENT; CELL SURVIVAL; CELLS, CULTURED; CHEMOKINES; CYTOKINES; DIPTERA; FLOW CYTOMETRY; HUMANS; INFLAMMATION; INTERLEUKIN-10; LARVA; LIPOPOLYSACCHARIDES; MONOCYTES; PHAGOCYTOSIS; STAPHYLOCOCCUS AUREUS; TEICHOIC ACIDS; WOUNDS AND INJURIES;

EID: 68449085618     PISSN: 0012186X     EISSN: 14320428     Source Type: Journal    
DOI: 10.1007/s00125-009-1432-6     Document Type: Article

References (51)

1. MJA van der Plas GN Jukema SW Wai 2008 Maggot excretions/secretions are differentially effective against biofilms of Staphylococcus aureus and Pseudomonas aeruginosa J Antimicrob Chemother 61 117 122
2. Editorial 2005 Putting feet first in diabetes Lancet 366 1674
3. RE Pecoraro GE Reiber EM Burgess 1990 Pathways to diabetic limb amputation. Basis for prevention Diabetes Care 13 513 521
4. AJ Boulton L Vileikyte G Ragnarson-Tennvall J Apelqvist 2005 The global burden of diabetic foot disease Lancet 366 1719 1724
5. EJ Peters MR Childs RP Wunderlich LB Harkless DG Armstrong LA Lavery 2001 Functional status of persons with diabetes-related lower-extremity amputations Diabetes Care 24 1799 1804
6. KY Mumcuoglu A Ingber L Gilead 1998 Maggot therapy for the treatment of diabetic foot ulcers Diabetes Care 21 2030 2031
7. RA Sherman 2003 Maggot therapy for treating diabetic foot ulcers unresponsive to conventional therapy Diabetes Care 26 446 451
8. P Steenvoorde CE Jacobi L van Doorn J Oskam 2007 Maggot debridement therapy of infected ulcers: patient and wound factors influencing outcome-a study on 101 patients with 117 wounds Ann R Coll Surg Engl 89 596 602
9. DG Armstrong P Salas B Short 2005 Maggot therapy in "lower-extremity hospice" wound care: fewer amputations and more antibiotic-free days J Am Podiatr Med Assoc 95 254 257
10. AJ Horobin KM Shakesheff DI Pritchard 2006 Promotion of human dermal fibroblast migration, matrix remodelling and modification of fibroblast morphology within a novel 3D model by Lucilia sericata larval secretions J Invest Dermatol 126 1410 1418
11. MJA van der Plas AM van der Does M Baldry 2007 Maggot excretions/secretions inhibit multiple neutrophil pro-inflammatory responses Microbes Infect 9 507 514
12. K Rosner C Ross T Karlsmark AA Petersen F Gottrup GL Vejlsgaard 1995 Immunohistochemical characterization of the cutaneous cellular infiltrate in different areas of chronic leg ulcers APMIS 103 293 299
13. MA Loots EN Lamme J Zeegelaar JR Mekkes JD Bos E Middelkoop 1998 Differences in cellular infiltrate and extracellular matrix of chronic diabetic and venous ulcers versus acute wounds J Invest Dermatol 111 850 857
14. C Wetzler H Kampfer B Stallmeyer J Pfeilschifter S Frank 2000 Large and sustained induction of chemokines during impaired wound healing in the genetically diabetic mouse: prolonged persistence of neutrophils and macrophages during the late phase of repair J Invest Dermatol 115 245 253
15. R Lobmann G Schultz H Lehnert 2005 Proteases and the diabetic foot syndrome: mechanisms and therapeutic implications Diabetes Care 28 461 471
16. PCJ Leijh M van der Barselaar MR Daha R van Furth 1982 Stimulation of the intracellular killing of Staphylococcus aureus by monocytes: regulation by immunoglobulin G and complement components C3/C3b and B/Bb J Immunol 129 332 337
17. G Koopman CP Reutelingsperger GA Kuijten RM Keehnen ST Pals MH van Oers 1994 Annexin V for flow cytometric detection of phosphatidylserine expression on B cells undergoing apoptosis Blood 84 1415 1420
18. PH Nibbering TP Zomerdijk AJ Corsel-Van Tilburg R van Furth 1990 Mean cell volume of human blood leucocytes and resident and activated murine macrophages J Immunol Methods 129 143 145
19. KY Mumcuoglu 2001 Clinical applications for maggots in wound care Am J Clin Dermatol 2 219 227
20. KY Mumcuoglu J Miller M Mumcuoglu M Friger M Tarshis 2001 Destruction of bacteria in the digestive tract of the maggot of Lucilia sericata (Diptera: Calliphoridae) J Med Entomol 38 161 166
21. W Robinson VH Norwood 1933 The role of surgical maggots in the disinfection of osteomyelitis and other infected wounds J Bone Jt Surg Am 15 409 412
22. P Steenvoorde GN Jukema 2004 The antimicrobial activity of maggots: in-vivo results J Tissue Viab 14 97 101
23. A Eigler B Siegmund U Emmerich KH Baumann G Hartmann S Endres 1998 Anti-inflammatory activities of cAMP-elevating agents: enhancement of IL-10 synthesis and concurrent suppression of TNF production J Leukoc Biol 63 101 107
24. Z Zidek 1999 Adenosine-cyclic AMP pathways and cytokine expression Eur Cytokine Netw 10 319 328
25. JS Fine HD Byrnes PJ Zavodny RW Hipkin 2001 Evaluation of signal transduction pathways in chemoattractant-induced human monocyte chemotaxis Inflammation 25 61 67
26. T Kaneko R Alvarez IF Ueki JA Nadel 1995 Elevated intracellular cyclic AMP inhibits chemotaxis in human eosinophils Cell Signal 7 527 534
27. T Bryn M Mahic JM Enserink F Schwede EM Aandahl K Tasken 2006 The cyclic AMP-Epac1-Rap1 pathway is dissociated from regulation of effector functions in monocytes but acquires immunoregulatory function in mature macrophages J Immunol 176 7361 7370
28. CH Serezani MN Ballinger DM Aronoff M Peters-Golden 2008 Cyclic AMP: master regulator of innate immune cell function Am J Respir Cell Mol Biol 39 127 132
29. F Soga N Katoh S Kishimoto 2007 Histamine prevents apoptosis in human monocytes Clin Exp Allergy 37 323 330 (Pubitemid 46393236)
30. L Ottonello R Gonella P Dapino C Sacchetti F Dallegri 1998 Prostaglandin E2 inhibits apoptosis in human neutrophilic polymorphonuclear leukocytes: role of intracellular cyclic AMP levels Exp Hematol 26 895 902
31. T Passeron T Namiki HJ Passeron E Le Pape VJ Hearing 2009 Forskolin protects keratinocytes from UVB-induced apoptosis and increases DNA repair independent of its effects on melanogenesis J Invest Dermatol 129 162 166
32. V Falanga 2005 Wound healing and its impairment in the diabetic foot Lancet 366 1736 1743
33. I Goren H Kampfer M Podda J Pfeilschifter S Frank 2003 Leptin and wound inflammation in diabetic ob/ob mice: differential regulation of neutrophil and macrophage influx and a potential role for the scab as a sink for inflammatory cells and mediators Diabetes 52 2821 2832
34. NJ Trengove H Bielefeldt-Ohmann MC Stacey 2000 Mitogenic activity and cytokine levels in non-healing and healing chronic leg ulcers Wound Repair Regen 8 13 25
35. N Yabunaka J Nishihira Y Mizue 2000 Elevated serum content of macrophage migration inhibitory factor in patients with type 2 diabetes Diabetes Care 23 256 258
36. Y Hirano M Shichijo M Deguchi 2007 Synergistic effect of PGD2 via prostanoid DP receptor on TNF-alpha-induced production of MCP-1 and IL-8 in human monocytic THP-1 cells Eur J Pharmacol 560 81 88
37. T Calandra T Roger 2003 Macrophage migration inhibitory factor: a regulator of innate immunity Nat Rev Immunol 3 791 800 (Pubitemid 37328657)
38. MS Agren M Werthen 2007 The extracellular matrix in wound healing: a closer look at therapeutics for chronic wounds Int J Low Extrem Wounds 6 82 97
39. R Lobmann A Ambrosch G Schultz K Waldmann S Schiweck H Lehnert 2002 Expression of matrix-metalloproteinases and their inhibitors in the wounds of diabetic and non-diabetic patients Diabetologia 45 1011 1016
40. RA Briggaman NM Schechter J Fraki GS Lazarus 1984 Degradation of the epidermal-dermal junction by proteolytic enzymes from human skin and human polymorphonuclear leukocytes J Exp Med 160 1027 1042
41. S Herrick G Ashcroft G Ireland M Horan C McCollum M Ferguson 1997 Up-regulation of elastase in acute wounds of healthy aged humans and chronic venous leg ulcers are associated with matrix degradation Lab Invest 77 281 288
42. SM Chen SI Ward OO Olutoye RF Diegelmann CI Kelman 1997 Ability of chronic wound fluids to degrade peptide growth factors is associated with increased levels of elastase activity and diminished levels of proteinase inhibitors Wound Repair Regen 5 23 32
43. G Lauer S Sollberg M Cole 2000 Expression and proteolysis of vascular endothelial growth factor is increased in chronic wounds J Invest Dermatol 115 12 18
44. NJ Trengove MC Stacey S MacAuley 1999 Analysis of the acute and chronic wound environments: the role of proteases and their inhibitors Wound Repair Regen 7 442 452
45. KA Gauss LK Nelson-Overton DW Siemsen Y Gao FR DeLeo MT Quinn 2007 Role of NF-kappaB in transcriptional regulation of the phagocyte NADPH oxidase by tumor necrosis factor-alpha J Leukoc Biol 82 729 741
46. B Meier 2001 Superoxide generation of phagocytes and nonphagocytic cells Protoplasma 217 117 124
47. WY Chen AA Rogers 2007 Recent insights into the causes of chronic leg ulceration in venous diseases and implications on other types of chronic wounds Wound Repair Regen 15 434 449
48. M Wlaschek K Scharffetter-Kochanek 2005 Oxidative stress in chronic venous leg ulcers Wound Repair Regen 13 452 461
49. T Skurk H Hauner 2004 Obesity and impaired fibrinolysis: role of adipose production of plasminogen activator inhibitor-1 Int J Obes Relat Metab Disord 28 1357 1364
50. S Lopez F Peiretti B Bonardo I Juhan-Vague G Nalbone 2000 Tumor necrosis factor alpha up-regulates in an autocrine manner the synthesis of plasminogen activator inhibitor type-1 during induction of monocytic differentiation of human HL-60 leukemia cells J Biol Chem 275 3081 3087
51. M Agirbasli 2005 Pivotal role of plasminogen-activator inhibitor 1 in vascular disease Int J Clin Pract 59 102 106