Effect of aqueous extract of bulbine natalensis baker stem on haematological and serum lipid profile of male Wistar rats

Indian Journal of Experimental Biology

Volumn 47, Issue 4, 2009, Pages 283-288

  Yakubu, M T ^a   Afolayan, A J ^a  

^a UNIVERSITY OF FORT HARE   (South Africa)

Author keywords

Bulbine natalensis; Haematological parameters; Localized systemic toxicity; Serum lipids

Indexed keywords

ANIMALIA; BULBINE; RATTUS NORVEGICUS;

LIPID; PLANT EXTRACT; WATER;

ANGIOSPERM; ANIMAL; ARTICLE; BLOOD; CHEMISTRY; DRUG EFFECT; HEMODYNAMICS; MALE; METABOLISM; PLANT STEM; RAT; WISTAR RAT;

ANIMALS; HEMODYNAMICS; LILIACEAE; LIPIDS; MALE; PLANT EXTRACTS; PLANT STEMS; RATS; RATS, WISTAR; WATER;

EID: 68349142121     PISSN: 00195189     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

References (27)

1. Van Erik Wrk B E, Van Oudtshoorn B & Gericke N, Medicinal plants of South Africa (Briza Publication, Pretoria, South Africa) 1997, 64.
2. Pujol J, Naturafrica-the herbalist Handbook. (Jean Pujol Natural Healers' Foundation, Durban, South Africa) 1990.
3. Yakubu M T & Afolayan A J, Effect of aqueous extract of Bulbine natalensis (Baker) stem on the sexual behaviour of male rats, Int J Androl, (2009) (in press).
4. Visavadiya N P & Narasimacharya A V, Hypolipidemic and antioxidant activities of Asparagus racemosus in hypercholesterolamic rats, Indian J Pharmacol, 37 (2005) 376.
5. Yakubu M T, Akanji M A & Oladiji A T, Alterations in serum lipid profile of male rats by oral administration of aqueous extract of Fadogia argrestis stem, Res J Med. Plant 2 (2008) 66.
6. Paolisso G, Manzella D, Rizzo M R, Ragno E, Beriberi M R, Varricchio G & Varrichio M, Elevated plasma fatty acid concentrations stimulate the cardiac autonomic nervous system in healthy subjects, Am J Clin Nutr, 72 (2000) 723.
7. nd edn (IL: Interstate Publishers, Danville) 1998.
8. Yakubu M T, Akanji M A & Oladiji A T, Haematological evaluation in male albino rats following chronic administration of aqueous extract of Fadogia agrestis stem, Pharmacog Mag, 3 (2007) 34.
9. Owoyele B V, Alabi O T, Adebayo J O, Soladoye A O, Abioye A I R & Jimoh S A, Haematologivcal evaluation of Ethanolic extract of Allium ascalonium in male albino rats, Fitoterapia, 75 (2004) 322.
10. Yakubu M T, Akanji M A & Oladiji A T, Aphrodisiac potentials of aqueous extract of Fadogia agrestis (Schweinf. Ex Heirn) stem in male albino rats, Asian J Androl, 7 (2005) 399.
11. nd edn. (W. B. Saunders Company, London) 1994, 1354.
12. Olson H, Betton G, Robinson D, Thomas K, Monro A, Kolaja G, Lilly P, Sanders J, Sipes G, Bracken W, Dorato M, Deun K V, Smith P, Berger B & Heller A, Concordance of toxicity of pharmaceuticals in humans and in animals, Reg Toxicol & Pharmacol, 32 (2000) 56.
13. Sanchez-Elsner T, Ramirez J R., Rodriguez-Sanz F, Varela E, Bernabew C & Botella L M A cross talk between hypoxia and TGF-beta orchestrates erythropoietin gene regulation through SPI and smads, J Mol Biol, 36 (2004) 9.
14. Adebayo J O, Adesokan A A, Olatunji L A, Buoro D O & Soladoye A O, Effect of Ethanolic extract of Bougainvillea spectabilis leaves on haematological and serum lipid variables in rats, Biokemistri, 17 (2005) 45.
15. McLellan S A, McClelland D B L & Walsh T S, Anaemia and red blood cell transfusion in the critically ill patient, Blood Rev, 17 (2003) 195.
16. th edition. (Lange Medical Books/McGraw Hill Companies Inc., New York) 2001, 500.
17. Chang-Gue S, Seung-Hyun H, Jung-Hyo C, Jang-Woo S, Chin-Ho C, Yeon-Weol L & Chong-Kwan C, Induction of hemopoiesis by saenghyuldan, a mixture of Ginseng radix, Paeoniae radix alba, and Hominis placenta extracts, Acta Pharmacologica Sinica, 24 (2003) 120.
18. th Edn, (Churchill Livingstone, Edinburg) 1995, 24.
19. Williams N & Levine R F, The origin, development and regulation of megakaryocytes, Br J Haematol, 52 (1982) 173.
20. Li J, Xia Y & Kuter D J, Interaction of thrombopoietin with the platelet complements receptor in plasma: binding, internalization, stability and pharmacokinetics, Brit J Haematol, 106 (1999) 345.
21. Grossmann A, Lenox J, Ren H P, Humes J M, Fortrom J W, Kaushansky K & Sprugel K H, Thrombopoietin accelerates platelet, red blood cell, and neutrophils' recovery in myelosuppressed rats, Expt Hematol, 24 (1996) 1238.
22. Rang A P, Dale M M & Ritter J M, Pharmacology. 3rd edn (Churchill Livingstone, New York) 1995, 409.
23. Treasure C B, Klein J L, Weintraub W S, Talley J D, Stillabow M E, Kisonski A S, Zhang J, Boccuzzi S J, Codarholm J C & Alexander R W, Beneficial effects of cholesterol lowering therapy on the coronary endothelium in patients with coronary heart disease, N Eng J Med, 332 (1995) 481.
24. Enas E A, Cholesterol made easy: The good, bad and the ugly. (CADI Research, USA) 1999, 1.
25. Miller N E, Hammett F, Saltosi S, Van Zeller H, Coltart J & Lewis B, Relation of angiographically defined coronary artery disease to plasma lipoprotein subfractions and apolipoproteins, Br Med J, 282 (1981) 1741.
26. Mayes P A, Lipid transport and storage, in Harper's biochemistry, edited by Murray R K, Granner D K, Mayes P A & Rodwell V W, 24th edition (Prentice Hall International, Inc., USA) 1996, 254.
27. Panagiotakos B, Pitsavos C, Skoumas J, Chrysohoou C, Toutouza M, Stefanadis C I & Toutouzas P K, Importance of LDL/HDL ratio as a predicator for coronary heart disease events in patients with heterozygous familial hypercholesterolemia: A 15 year follow-up (1987-2002), Curr Med Res & Opin, 19 (2003) 89.