Glucose variability in critically ill patients

Yearbook of Intensive Care and Emergency Medicine 2009

Volumn , Issue , 2007, Pages 728-737

  Ali, N A ^a   Krinsley, J S ^b   Preiser, J C ^c  

^a Department of Internal Medicine   (United States)

^b Columbia University College of Physicians and Surgeons ^*  (United States)

^c UNIVERSITY OF LIÈGE   (Belgium)

Author keywords

[No Author keywords available]

Indexed keywords

EID: 68349116622     PISSN: None     EISSN: None     Source Type: Book    
DOI: 10.1007/978-0-387-92278-2_67     Document Type: Chapter

References (41)

1. Ali NA, O'Brien JM Jr, Blum W, et al (2007) Hyperglycemia in patients with acute myeloid leukemia is associated with increased hospital mortality. Cancer 110: 96-102
2. Umpierrez GE, Isaacs SD, Bazargan N, You X, Thaler LM, Kitabchi AE (2002) Hyperglycemia: an independent marker of in-hospital mortality in patients with undiagnosed diabetes. J Clin Endocrinol Metab 87: 978-982
3. Norhammar A, Tenerz A, Nilsson G, et al (2002) Glucose metabolism in patients with acute myocardial infarction and no previous diagnosis of diabetes mellitus: a prospective study. Lancet 359: 2140-2144
4. Silverman RA, Pahk R, Carbone M, et al (2006) The Relationship of Plasma Glucose and HbA1c Levels among Emergency Department Patients with No Prior History of Diabetes Mellitus. Acad Emerg Med 13: 722-726
5. Van den Berghe G, Wouters P, Weekers F, et al (2001) Intensive insulin therapy in the critically ill patients. N Engl J Med 345: 1359-1367
6. Van den Berghe G, Wilmer A, Hermans G, et al (2006) Intensive insulin therapy in the medical ICU. N Engl J Med 354: 449-461
7. Brunkhorst FM, Engel C, Bloos F, et al (2008) Intensive Insulin Therapy and Pentastarch Resuscitation in Severe Sepsis. N Engl J Med 358: 125-139
8. Wilson M, Weinreb J, Hoo GW (2007) Intensive insulin therapy in critical care: A review of 12 protocols. Diabetes Care. 30: 1005-1011
9. Morris AH, Orme JF Jr, Truwit JD, et al (2008) A replicable method for blood glucose control in critically Ill patients. Crit Care Med 36: 1787-1795
10. Marik PE, Raghavan M (2004) Stress-hyperglycemia, insulin and immunomodulation in sepsis. Intensive Care Med 30: 748-756
11. McCowen KC, Malhotra A, Bistrian BR (2001) Stress-induced hyperglycemia. Critical care clinics 17: 107-124
12. Wahl WL, Taddonio M, Maggio PM, Arbabi S, Hemmila MR. (2008) Mean glucose values predict trauma patient mortality. J Trauma 65: 42-48
13. Krinsley JS (2004) Effect of an intensive glucose management protocol on the mortality of critically ill adult patients. Mayo Clin Proc 79: 992-1000
14. Preiser JC, Devos P (2008) Clinical experience with tight glucose control by intensive insulin therapy. Crit Care Med 35:S503-S507
15. Van den Berghe G, Wilmer A, Milants I, et al (2006) Intensive insulin therapy in mixed medical/surgical intensive care units: benefit versus harm. Diabetes 55: 3151-3159
16. Egi M, Bellomo R, Stachowski E, et al (2008) Blood glucose concentration and outcome of critical illness: the impact of diabetes. Crit Care Med 36: 2249-2255
17. Krinsley JS (2006) Glycemic control, diabetic status, and mortality in a heterogeneous population of critically ill patients before and during the era of intensive glycemic management: six and one-half years experience at a university-affiliated community hospital. Semin Thorac Cardiovasc Surg 18: 317-325
18. Devos P, Preiser JC, Melot C (2007) Impact of tight glucose control by intensive insulin therapy on ICU mortality and the rate of hypoglycaemia: final results of the Glucontrol study. Intensive Care Med 33 (Suppl 2): S189 (abst)
19. Ryan EA, Shandro T, Green K, et al (2004) Assessment of the severity of hypoglycemia and glycemic lability in type 1 diabetic subjects undergoing islet transplantation. Diabetes 53: 955-962
20. Kovatchev BP, Otto E, Cox D, Gonder-Frederick L, Clarke W (2006) Evaluation of a new measure of blood glucose variability in diabetes. Diabetes Care 29: 2433-2438
21. Egi M, Bellomo R, Stachowski E, French CJ, Hart G (2006) Variability of blood glucose concentration and short-term mortality in critically ill patients. Anesthesiology 105: 244-252
22. Krinsley JS (2008) Glycemic variability: A strong independent predictor of mortality in critically ill patients. Crit Care Med 36: 3008-3013
23. Dossett LA, Cao H, Mowery NT, Dortch MJ, Morris JM Jr, May AK (2008) Blood glucose variability is associated with mortality in the surgical intensive care unit. Am Surg 74: 679-685
24. Hirshberg E, Larsen G, Van Duker H (2008) Alterations in glucose homeostasis in the pediatric intensive care unit: Hyperglycemia and glucose variability are associated with increased mortality and morbidity. Pediatr Crit Care Med 9: 361-366
25. Wintergerst KA, Buckingham B, Gandrud L, Wong BJ, Kache S, Wilson DM (2006) Association of hypoglycemia, hyperglycemia, and glucose variability with morbidity and death in the pediatric intensive care unit. Pediatrics 118: 173-179
26. Ali NA, O'Brien JM Jr, Dungan K, et al (2008) Glucose variability and mortality in patients with sepsis. Crit Care Med 36: 2316-2321
27. Risso A, Mercuri F, Quagliaro L, Damante G, Ceriello A (2001) Intermittent high glucose enhances apoptosis in human umbilical vein endothelial cells in culture. Am J Physiol Endocrinol Metab 281: E924-E930
28. Collier B, Dossett LA, May AK, Diaz JJ (2008) Glucose control and the inflammatory Response. Nutr Clin Pract 23: 3-15
29. Otto N, Schindler R, Lun A, Boenisch O, Frei U, Oppert M (2008) Hyperosmotic stress enhances cytokine production and decreases phagocytosis in vitro. Crit Care 12:R107
30. Van den Berghe G, Schoonheydt K, Becx P, Bruyninckx F, Wouters PJ (2005) Insulin therapy protects the central and peripheral nervous system of intensive care patients. Neurology 64: 1348-1353
31. Capes SE, Hunt D, Malmberg K, Pathak P, Gerstein HC (2001) Stress hyperglycemia and prognosis of stroke in nondiabetic and diabetic patients: A systematic overview. Stroke 32: 2426-2432
32. Schiekofer S, Andrassy M, Chen J, et al (2003) Acute hyperglycemia causes intracellular formation of CML and activation of ras, p42/44 MAPK, and nuclear factor {kappa}B in PBMCs. Diabetes 52: 621-633
33. Monnier L, Mas E, Ginet C, et al (2006) Activation of oxidative stress by acute glucose fluctuations compared with sustained chronic hyperglycemia in patients with type 2 diabetes. JAMA 295: 1681-1687
34. Holtfreter B, Bandt C, Kuhn SO, et al (2006) Serum osmolality and outcome in intensive care unit patients. Acta Anaesthesiol Scand 50: 970-977
35. Dungan K, Chapman J, Braithwaite SS, Buse J (2007) Glucose measurement: confounding issues in setting targets for inpatient management. Diabetes Care 30: 403-409
36. Suh SW, Gum ET, Hamby AM, Chan PH, Swanson RA (2007) Hypoglycemic neuronal death is triggered by glucose reperfusion and activation of neuronal NADPH oxidase. J Clin Invest 117: 910-918
37. Rossetti P, Porcellati F, Fanelli CG, Perriello G, Torlone E, Bolli GB (2008) Superiority of insulin analogues versus human insulin in the treatment of diabetes mellitus. Arch Physiol Biochem 114: 3-10
38. Vriesendorp TM, van Santen S, DeVries JH, et al (2006) Predisposing factors for hypoglycemia in the intensive care unit. Crit Care Med 34: 96-101
39. Pieracci F, Hydo L, Eachempati S, Pomp A, Shou J, Barie PS (2008) Higher body mass index predicts need for insulin but not hyperglycemia, nosocomial infection, or death in critically ill surgical patients. Surg Infect (Larchmt) 9: 121-130
40. Rusavy Z, Sramek V, Lacigova S, Novak I, Tesinsky P, Macdonald IA (2004) Influence of insulin on glucose metabolism and energy expenditure in septic patients. Crit Care 8:R213-R220
41. Wiener RS, Wiener DC, Larson RJ (2008) Benefits and risks of tight glucose control in critically ill adults: A meta-analysis. JAMA 300: 933-944