Targeting of protease 2A genome by single and multiple siRNAS as a strategy to impair CVB3 life cycle in permissive HeLa cells

Methods and Findings in Experimental and Clinical Pharmacology

Volumn 31, Issue 2, 2009, Pages 63-70

  Racchi, Giorgia ^a   Klingel, Karin ^a   Kandolf, Reinhard ^a   Grassi, Gabriele ^a,b,c  

^a UNIVERSITY HOSPITAL TÜBINGEN   (Germany)

^b UNIVERSITY OF TRIESTE   (Italy)

^c UNIVERSITY OF TRIESTE   (Italy)

Author keywords

Coxsackievirus B3; Protease 2A; siRNA; Transfection

Indexed keywords

LACTATE DEHYDROGENASE; LIPOFECTAMINE; LIPOFECTIN; LUCIFERASE; MESSENGER RNA; PROTEASE 2A; PROTEIN VP1; PROTEINASE; SIRNA 3541; SIRNA 3626; SIRNA GL 2; SMALL INTERFERING RNA; UNCLASSIFIED DRUG; VIRUS ENZYME; VIRUS PROTEIN; VIRUS RNA; CAPSID PROTEIN; CYSTEINE PROTEINASE; PICORNAIN 2A, PICORNAVIRUS;

ANIMAL CELL; ARTICLE; CELL SHAPE; CELL VIABILITY; CONTROLLED STUDY; COXSACKIE VIRUS B3; COXSACKIE VIRUS INFECTION; CYTOTOXICITY; DRUG EFFECT; GENE TARGETING; GENETIC TRANSFECTION; HELA CELL; HUMAN; HUMAN CELL; LIPOSOMAL GENE DELIVERY SYSTEM; NONHUMAN; PROTEASE 2A GENE; RNA INTERFERENCE; VIRION; VIRUS CAPSID; VIRUS GENE; VIRUS GENOME; VIRUS MYOCARDITIS; CELL SURVIVAL; ENTEROVIRUS; GENETICS; METHODOLOGY; MYOCARDITIS; VIROLOGY;

CAPSID PROTEINS; CELL SURVIVAL; COXSACKIEVIRUS INFECTIONS; CYSTEINE ENDOPEPTIDASES; ENTEROVIRUS B, HUMAN; GENOME, VIRAL; HELA CELLS; HUMANS; MYOCARDITIS; RNA, SMALL INTERFERING; TRANSFECTION; VIRAL PROTEINS; VIRION;

EID: 68349104491     PISSN: 03790355     EISSN: None     Source Type: Journal    
DOI: 10.1358/mf.2009.31.2.1354129     Document Type: Article

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