Competitive displacement of serum protein binding of radiopharmaceuticals with amino acid infusion investigated with N-isopropyl-p-123I- iodoamphetamine

Journal of Nuclear Medicine

Volumn 50, Issue 8, 2009, Pages 1378-1383

  Kuga, Noriyuki ^a,b   Shikano, Naoto ^c   Takamura, Norito ^d   Nishii, Ryuichi ^e   Yamasaki, Keishi ^f   Kobayashi, Masato ^g   Nagamachi, Shigeki ^a   Tamura, Shozo ^a   Kawai, Keiichi ^b,g  

^a UNIVERSITY OF MIYAZAKI HOSPITAL   (Japan)

^b KANAZAWA UNIVERSITY   (Japan)

^c IBARAKI PREFECTURAL UNIVERSITY OF HEALTH SCIENCES   (Japan)

^d KYUSHU UNIVERSITY OF HEALTH AND WELFARE   (Japan)

^e UNIVERSITY OF FUKUI   (Japan)

^f SOJO UNIVERSITY   (Japan)

^g UNIVERSITY OF FUKUI   (Japan)

Author keywords

123I IMP; Amino acid infusion; Cerebral accumulation; Displacement; Serum protein binding

Indexed keywords

AMINO ACID; CARBON 14; DIAZEPAM; HUMAN SERUM ALBUMIN; IOFETAMINE I 123; KIDOMIN; OROSOMUCOID; PROPRANOLOL; PROTEAMIN; TRITIUM; UNCLASSIFIED DRUG; VERAPAMIL; WARFARIN;

AMINO ACID COMPOSITION; ARTICLE; CLINICAL ARTICLE; CONTROLLED STUDY; DRUG ACCUMULATION; DRUG BINDING SITE; DRUG PROTEIN BINDING; FEMALE; HUMAN; HUMAN EXPERIMENT; ISOTOPE LABELING; MALE; MONKEY; NORMAL HUMAN; PRIORITY JOURNAL; ULTRAFILTRATION;

AMINO ACIDS; ANIMALS; BLOOD PROTEINS; BRAIN; HAPLORHINI; INFUSIONS, INTRA-ARTERIAL; IOFETAMINE; PROTEIN BINDING; RADIOPHARMACEUTICALS;

EID: 68249144251     PISSN: 01615505     EISSN: None     Source Type: Journal    
DOI: 10.2967/jnumed.108.060095     Document Type: Article

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