Serum protein binding displacement: theoretical analysis using a hypothetical radiopharmaceutical and experimental analysis with 123I-N-isopropyl-p-iodoamphetamine

Nuclear Medicine and Biology

Volumn 36, Issue 1, 2009, Pages 99-106

  Kawai, Keiichi ^a,b   Nishii, Ryuichi ^c   Shikano, Naoto ^d   Makino, Nobuo ^d   Kuga, Noriyuki ^a,e   Yoshimoto, Mitsuyoshi ^a   Jinnouchi, Seishi ^f   Nagamachi, Shigeki ^f   Tamura, Shozo ^f   Takamura, Norito ^g  

^a KANAZAWA UNIVERSITY   (Japan)

^b UNIVERSITY OF FUKUI   (Japan)

^c Shiga Medical Center Research Institute   (Japan)

^d IBARAKI PREFECTURAL UNIVERSITY OF HEALTH SCIENCES   (Japan)

^e UNIVERSITY OF MIYAZAKI HOSPITAL   (Japan)

^f UNIVERSITY OF MIYAZAKI   (Japan)

^g KYUSHU UNIVERSITY OF HEALTH AND WELFARE   (Japan)

Author keywords

Human serum albumin; N Isopropyl p iodoamphetamine; Pharmacokinetics; Protein binding

Indexed keywords

6 METHOXY 2 NAPHTHYLACETIC ACID; ERYTHROMYCIN; IOFETAMINE I 123; OROSOMUCOID; SERUM ALBUMIN;

ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; BINDING COMPETITION; CONTROLLED STUDY; DRUG BINDING SITE; DRUG PROTEIN BINDING; FEMALE; HUMAN; HUMAN TISSUE; HYPOTHESIS; MONKEY; NONHUMAN; RAT; THEORETICAL MODEL; THEORETICAL STUDY;

ANIMALS; BINDING SITES; BINDING, COMPETITIVE; BLOOD PROTEINS; DRUG INTERACTIONS; ERYTHROMYCIN; FEMALE; HAPLORHINI; HUMANS; INJECTIONS, INTRAVENOUS; IOFETAMINE; LIGANDS; MODELS, BIOLOGICAL; NAPHTHALENEACETIC ACIDS; OROSOMUCOID; PROTEIN BINDING; RADIOPHARMACEUTICALS; RATS; SERUM ALBUMIN; TISSUE DISTRIBUTION; WHOLE BODY IMAGING;

EID: 58749112406     PISSN: 09698051     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.nucmedbio.2008.10.005     Document Type: Article

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