Synergistic attenuation of myocardial fibrosis in spontaneously hypertensive rats by joint treatment with benazepril and candesartan

Journal of Cardiovascular Pharmacology

Volumn 54, Issue 1, 2009, Pages 16-24

  Meng, Guoliang ^a   Wu, Feng ^a   Yang, Liyun ^a   Zhu, Hongyan ^a   Gu, Jinhua ^a   He, Min ^a   Xu, Jiliang ^a  

^a NANTONG MEDICAL COLLEGE   (China)

Author keywords

Myocardial fibrosis; Smad; Spontaneous hypertensive rats; Synergistic attenuation; Transforming growth factor

Indexed keywords

BENAZEPRIL; CANDESARTAN; COLLAGEN; DIPEPTIDYL CARBOXYPEPTIDASE INHIBITOR; SMAD PROTEIN; TRANSFORMING GROWTH FACTOR BETA1;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; CONTROLLED STUDY; DRUG DOSE TITRATION; ECHOCARDIOGRAPHY; HEART MUSCLE FIBROSIS; HISTOPATHOLOGY; MALE; NONHUMAN; PRIORITY JOURNAL; PROTEIN CROSS LINKING; RAT; SPONTANEOUSLY HYPERTENSIVE RAT; WESTERN BLOTTING;

ANGIOTENSIN II TYPE 1 RECEPTOR BLOCKERS; ANGIOTENSIN-CONVERTING ENZYME INHIBITORS; ANIMALS; BENZAZEPINES; BENZIMIDAZOLES; DRUG SYNERGISM; DRUG THERAPY, COMBINATION; FIBROSIS; MYOCARDIUM; RATS; RATS, INBRED SHR; TETRAZOLES;

EID: 68249141425     PISSN: 01602446     EISSN: None     Source Type: Journal    
DOI: 10.1097/FJC.0b013e3181a98b31     Document Type: Article

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