Detection of reduced GABA synthesis following inhibition of GABA transaminase using in vivo magnetic resonance signal of [13C]GABA C1

Journal of Neuroscience Methods

Volumn 182, Issue 2, 2009, Pages 236-243

  Yang, Jehoon ^a,b   Johnson, Christopher ^a   Shen, Jun ^a  

^a NATIONAL INSTITUTE OF MENTAL HEALTH   (United States)

^b Samsung Medical Center   (South Korea)

Author keywords

13C; GABA; Glucose metabolism; Magnetic resonance spectroscopy; Proton decoupling

Indexed keywords

4 AMINOBUTYRATE AMINOTRANSFERASE; 4 AMINOBUTYRIC ACID; AMIDE; CARBON 13; CARBOXYLIC ACID; GABACULINE; GLUCOSE; GLUTAMINE; ISOTOPE; PROTON;

AMINO ACID SYNTHESIS; ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; BRAIN METABOLISM; BRAIN TISSUE; CONTROLLED STUDY; IN VIVO STUDY; MAGNETIC FIELD; MALE; NEUROTRANSMISSION; NONHUMAN; NUCLEAR MAGNETIC RESONANCE SPECTROSCOPY; PRIORITY JOURNAL; RAT;

4-AMINOBUTYRATE TRANSAMINASE; ANIMALS; BRAIN CHEMISTRY; CARBON ISOTOPES; CYCLOHEXANECARBOXYLIC ACIDS; ELECTROMAGNETIC FIELDS; ENZYME INHIBITORS; GAMMA-AMINOBUTYRIC ACID; IMAGE PROCESSING, COMPUTER-ASSISTED; ISOTOPE LABELING; MAGNETIC RESONANCE SPECTROSCOPY; RATS; SIGNAL PROCESSING, COMPUTER-ASSISTED;

EID: 68249132561     PISSN: 01650270     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.jneumeth.2009.06.015     Document Type: Article

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