Antidepressant treatment facilitates dopamine release and drug seeking behavior in a genetic animal model of depression

European Journal of Neuroscience

Volumn 30, Issue 3, 2009, Pages 485-492

  Roth Deri, Ilana ^a   Friedman, Alexander ^a   Abraham, Lital ^a   Lax, Elad ^a   Flaumenhaft, Yakov ^a   Dikshtein, Yahav ^a   Yadid, Gal ^a  

^a BAR ILAN UNIVERSITY   (Israel)

Author keywords

Addiction; Cocaine; Depression; Dopamine; Nucleus accumbens; Reward

Indexed keywords

COCAINE; DESIPRAMINE; DOPAMINE; VANOXERINE;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; CELL LEVEL; COCAINE DEPENDENCE; CONTROLLED STUDY; DEPRESSION; DOPAMINE RELEASE; DOPAMINERGIC TRANSMISSION; LONG TERM CARE; MALE; NONHUMAN; NUCLEUS ACCUMBENS; PRIORITY JOURNAL; RAT; REWARD; TASK PERFORMANCE;

ANIMALS; ANTIDEPRESSIVE AGENTS; AUTORADIOGRAPHY; BEHAVIOR, ADDICTIVE; BEHAVIOR, ANIMAL; COCAINE; DEPRESSION; DISEASE MODELS, ANIMAL; DOPAMINE; DOPAMINE UPTAKE INHIBITORS; MICRODIALYSIS; NUCLEUS ACCUMBENS; RATS;

EID: 68249128254     PISSN: 0953816X     EISSN: 14609568     Source Type: Journal    
DOI: 10.1111/j.1460-9568.2009.06840.x     Document Type: Article

References (32)

1. Crown, W.H., Finkelstein, S., Berndt, E.R., Ling, D., Poret, A.W., Rush, A.J. Russell, J.M. (2002) The impact of treatment-resistant depression on health care utilization and costs. J. Clin. Psychiatry, 63, 963 971.
2. Delfs, J.M., Zhu, Y., Druhan, J.P. Aston-Jones, G. (2000) Noradrenaline in the ventral forebrain is critical for opiate withdrawal-induced aversion. Nature, 403, 430 434.
3. Dremencov, E., Newman, M.E., Kinor, N., Blatman-Jan, G., Schindler, C.J., Overstreet, D.H. Yadid, G. (2005) Hyperfunctionality of serotonin-2C receptor-mediated inhibition of accumbal dopamine release in an animal model of depression is reversed by antidepressant treatment. Neuropharmacology, 48, 34 42.
4. Eison, A.S., Eison, M.S., Torrente, J.R., Wright, R.N. Yocca, F.D. (1990) Nefazodone: preclinical pharmacology of a new antidepressant. Psychopharmacol. Bull., 26, 311 315.
5. Fagergren, P., Overstreet, D.H., Goiny, M. Hurd, Y.L. (2005) Blunted response to cocaine in the Flinders hypercholinergic animal model of depression. Neuroscience, 132, 1159 1171.
6. Friedman, A., Dremencov, E., Crown, H., Levy, D., Mintz, M., Overstreet, D.H. Yadid, G. (2005) Variability of the mesolimbic neuronal activity in a rat model of depression. Neuroreport, 16, 513 516.
7. Friedman, A., Deri, I., Friedman, Y., Dremencov, E., Goutkin, S., Kravchinsky, E., Mintz, M., Levi, D., Overstreet, D.H. Yadid, G. (2007) Decoding of dopaminergic mesolimbic activity and depressive behavior. J. Mol. Neurosci., 32, 72 79.
8. Friedman, A., Friedman, Y., Dremencov, E. Yadid, G. (2008) VTA dopamine neuron bursting is altered in an animal model of depression and corrected by desipramine. J. Mol. Neurosci., 34, 201 209.
9. Friedman, A., Frankel, M., Flaumenhaft, Y., Merenlender, A., Pinhasov, A., Feder, Y., Taler, M., Gil-Ad, I., Abeles, M. Yadid, G. (2009) Programmed acute electrical stimulation of ventral tegmental area alleviates depressive-like behavior. Neuropsychopharmacology, 34, 1057 1066.
10. Georges, F. Aston-Jones, G. (2001) Potent regulation of midbrain dopamine neurons by the bed nucleus of the stria terminalis. J. Neurosci., 21, RC160.
11. Georges, F. Aston-Jones, G. (2002) Activation of ventral tegmental area cells by the bed nucleus of the stria terminalis: a novel excitatory amino acid input to midbrain dopamine neurons. J. Neurosci., 22, 5173 5187.
12. Gershon, A.A., Vishne, T. Grunhaus, L. (2007) Dopamine D2-like receptors and the antidepressant response. Biol. Psychiatry, 61, 145 153.
13. Gifford, A.N., Bergmann, J.S. Johnson, K.M. (1993) GBR 12909 fails to antagonize cocaine-induced elevation of dopamine in striatal slices. Drug Alcohol Depend., 32, 65 71.
14. Honer, W.G., Falkai, P., Bayer, T.A., Xie, J., Hu, L., Li, H.Y., Arango, V., Mann, J.J., Dwork, A.J. Trimble, W.S. (2002) Abnormalities of SNARE mechanism proteins in anterior frontal cortex in severe mental illness. Cereb. Cortex, 12, 349 356.
15. Hyttel, J. (1994) Pharmacological characterization of selective serotonin reuptake inhibitors (SSRIs). Int. Clin. Psychopharmacol., 9 (Suppl 1 19 26.
16. Koob, G.F. Le Moal, M. (2008) Review. Neurobiological mechanisms for opponent motivational processes in addiction. Philos. Trans. R. Soc. Lond. B Biol. Sci., 363, 3113 3123.
17. Markou, A., Kosten, T.R. Koob, G.F. (1998) Neurobiological similarities in depression and drug dependence: a self-medication hypothesis. Neuropsychopharmacology, 18, 135 174.
18. Naranjo, C.A., Tremblay, L.K. Busto, U.E. (2001) The role of the brain reward system in depression. Prog. Neuropsychopharmacol. Biol. Psychiatry, 25, 781 823.
19. Overstreet, D.H., Friedman, E., Mathe, A.A. Yadid, G. (2005) The Flinders Sensitive Line rat: a selectively bred putative animal model of depression. Neurosci. Biobehav. Rev., 29, 739 759.
20. Regier, D.A., Farmer, M.E., Rae, D.S., Locke, B.Z., Keith, S.J., Judd, L.L. Goodwin, F.K. (1990) Comorbidity of mental disorders with alcohol and other drug misuse. Results from the Epidemiologic Catchment Area (ECA) Study. JAMA, 264, 2511 2518.
21. Rocha, B.A. (2003) Stimulant and reinforcing effects of cocaine in monoamine transporter knockout mice. Eur. J. Pharmacol., 479, 107 115.
22. Roth-Deri, I., Zangen, A., Aleli, M., Goelman, R.G., Pelled, G., Nakash, R., Gispan-Herman, I., Green, T., Shaham, Y. Yadid, G. (2003) Effect of experimenter-delivered and self-administered cocaine on extracellular beta-endorphin levels in the nucleus accumbens. J. Neurochem., 84, 930 938.
23. Rothman, R.B. Glowa, J.R. (1995) A review of the effects of dopaminergic agents on humans, animals, and drug-seeking behavior, and its implications for medication development.Focus on GBR 12909. Mol. Neurobiol., 11, 1 19.
24. Rothman, R.B., Baumann, M.H., Prisinzano, T.E. Newman, A.H. (2008) Dopamine transport inhibitors based on GBR12909 and benztropine as potential medications to treat cocaine addiction. Biochem. Pharmacol., 75, 2 16.
25. Schwartz, K., Yadid, G., Weizmann, A. Rehavi, M. (2003) Decreased limbic vesicular monoamine transporter 2 in a genetic rat model of depression. Brain Res., 965, 174 179.
26. Tella, S.R. (1995) Effects of monoamine reuptake inhibitors on cocaine self-administration in rats. Pharmacol. Biochem. Behav., 51, 687 692.
27. Wu, P., Hoven, C.W., Liu, X., Fuller, C.J., Fan, B., Musa, G., Wicks, J., Mandell, D. Cook, J.A. (2008) The relationship between depressive symptom levels and subsequent increases in substance use among youth with severe emotional disturbance. J. Stud. Alcohol Drugs, 69, 520 527.
28. Yadid, G. Friedman, A. (2008) Dynamics of the dopaminergic system as a key component to the understanding of depression. Prog. Brain Res., 172, 265 286.
29. Yadid, G., Pacak, K., Kopin, I.J. Goldstein, D.S. (1994) Endogenous serotonin stimulates striatal dopamine release in conscious rats. J. Pharmacol. Exp. Ther., 270, 1158 1165.
30. Yadid, G., Nakash, R., Deri, I., Tamer, G., Kinor, N., Gispan, I. Zangen, A. (2000) Elucidation of the neurobiology of depression: insights from a novel genetic animal model. Prog. Neurobiol., 62, 353 378.
31. Zangen, A., Overstreet, D.H. Yadid, G. (1999) Increased catecholamine levels in specific brain regions of a rat model of depression: normalization by chronic antidepressant treatment. Brain Res., 824, 243 250.
32. Zangen, A., Nakash, R., Overstreet, D.H. Yadid, G. (2001) Association between depressive behavior and absence of serotonin-dopamine interaction in the nucleus accumbens. Psychopharmacology (Berl), 155, 434 439.