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Volumn 339, Issue 7713, 2009, Pages 161-164

Science, medicine, and the future. Cell-free fetal DNA and RNA in maternal blood: Implications for safer antenatal testing

Author keywords

[No Author keywords available]

Indexed keywords

DNA; RNA;

EID: 68249114716     PISSN: None     EISSN: 17561833     Source Type: Journal    
DOI: 10.1136/bmj.b2451     Document Type: Review
Times cited : (35)

References (33)
  • 1
    • 0342618532 scopus 로고    scopus 로고
    • Presence of fetal DNA in maternal plasma and serum
    • CrossRef][Web of Science][Medline
    • Lo YMD, Corbetta N, Chamberlain PF, Rai V, Sargent IL, Redman CW, et al. Presence of fetal DNA in maternal plasma and serum. Lancet 1997;350:485-7.[CrossRef][Web of Science][Medline]
    • (1997) Lancet , vol.350 , pp. 485-487
    • Lo, Y.M.D.1    Corbetta, N.2    Chamberlain, P.F.3    Rai, V.4    Sargent, I.L.5    Redman, C.W.6
  • 2
    • 34548405957 scopus 로고    scopus 로고
    • Procedure-related complications of amniocentesis and chorionic villous sampling: A systematic review
    • CrossRef][Web of Science][Medline
    • Mujezinovic F, Alfirevic Z. Procedure-related complications of amniocentesis and chorionic villous sampling: a systematic review. Obstet Gynecol 2007;110:687-94.[CrossRef][Web of Science][Medline]
    • (2007) Obstet Gynecol , vol.110 , pp. 687-694
    • Mujezinovic, F.1    Alfirevic, Z.2
  • 3
    • 34347230507 scopus 로고    scopus 로고
    • Free fetal DNA in maternal plasma in anembryonic pregnancies: Confirmation that the origin is the trophoblast
    • CrossRef][Medline
    • Alberry M, Maddocks D, Jones M, Abdel Hadi M, Abdel-Fattah S, Avent ND, et al. Free fetal DNA in maternal plasma in anembryonic pregnancies: confirmation that the origin is the trophoblast. Prenat Diagn 2007;27:415-8.[CrossRef][Medline]
    • (2007) Prenat Diagn , vol.27 , pp. 415-418
    • Alberry, M.1    Maddocks, D.2    Jones, M.3    Abdel Hadi, M.4    Abdel-Fattah, S.5    Avent, N.D.6
  • 4
    • 1642574222 scopus 로고    scopus 로고
    • Size distributions of maternal and fetal DNA in maternal plasma
    • Abstract/Free Full Text
    • Chan KCA, Zhang J, Hui ABY, Wong N, Lau TK, Leung TN, et al. Size distributions of maternal and fetal DNA in maternal plasma. Clin Chem 2004;50:88-92.[Abstract/Free Full Text]
    • (2004) Clin Chem , vol.50 , pp. 88-92
    • Chan, K.C.A.1    Zhang, J.2    Hui, A.B.Y.3    Wong, N.4    Lau, T.K.5    Leung, T.N.6
  • 5
    • 54049132561 scopus 로고    scopus 로고
    • Lun FMF, Chiu RWK, Allen Chan KC, Yeung Leung T, Kin Lau T, Dennis Lo YM. Microfluidics digital PCR reveals a higher than expected fraction of fetal DNA in maternal plasma. Clin Chem 2008;54:1664-72.[Abstract/Free Full Text]
    • Lun FMF, Chiu RWK, Allen Chan KC, Yeung Leung T, Kin Lau T, Dennis Lo YM. Microfluidics digital PCR reveals a higher than expected fraction of fetal DNA in maternal plasma. Clin Chem 2008;54:1664-72.[Abstract/Free Full Text]
  • 6
    • 34548501087 scopus 로고    scopus 로고
    • Early detection of cell-free fetal DNA in maternal plasma
    • CrossRef][Web of Science][Medline
    • Illanes S, Denbow M, Kailasam C, Finning K, Soothill PW. Early detection of cell-free fetal DNA in maternal plasma. Early Hum Dev 2007;83:563-6.[CrossRef][Web of Science][Medline]
    • (2007) Early Hum Dev , vol.83 , pp. 563-566
    • Illanes, S.1    Denbow, M.2    Kailasam, C.3    Finning, K.4    Soothill, P.W.5
  • 8
    • 0033762298 scopus 로고    scopus 로고
    • Presence of fetal RNA in maternal plasma
    • Free Full Text
    • Poon LLM, Leung TN, Lau TK, Lo YMD. Presence of fetal RNA in maternal plasma. Clin Chem 2000;46:1832-4.[Free Full Text]
    • (2000) Clin Chem , vol.46 , pp. 1832-1834
    • Poon, L.L.M.1    Leung, T.N.2    Lau, T.K.3    Lo, Y.M.D.4
  • 9
    • 33845539572 scopus 로고    scopus 로고
    • MALDI-TOF mass spectrometry compared with real-time PCR for detection of fetal cell-free DNA in maternal plasma
    • Free Full Text
    • Li Y, Holzgreve W, Kiefer V, Hahn S. MALDI-TOF mass spectrometry compared with real-time PCR for detection of fetal cell-free DNA in maternal plasma. Clin Chem 2006;52:2311-2.[Free Full Text]
    • (2006) Clin Chem , vol.52 , pp. 2311-2312
    • Li, Y.1    Holzgreve, W.2    Kiefer, V.3    Hahn, S.4
  • 10
    • 34548727890 scopus 로고    scopus 로고
    • Digital PCR for the molecular detection of fetal chromosomal aneuploidy
    • Abstract/Free Full Text
    • Lo YMD, Lun FMF, Chan KCA, Tsui NBY, Chong KC, Lau TK, et al. Digital PCR for the molecular detection of fetal chromosomal aneuploidy. Proc Natl Acad Sci USA 2007;104:13116-21. [Abstract/Free Full Text]
    • (2007) Proc Natl Acad Sci USA , vol.104 , pp. 13116-13121
    • Lo, Y.M.D.1    Lun, F.M.F.2    Chan, K.C.A.3    Tsui, N.B.Y.4    Chong, K.C.5    Lau, T.K.6
  • 11
    • 55849124028 scopus 로고    scopus 로고
    • Noninvasive diagnosis of fetal aneuploidy by shotgun sequencing DNA from maternal blood
    • Abstract/Free Full Text
    • Fan HC, Blumenfeld YJ, Chitkara U, Hudgins L, Quake SR. Noninvasive diagnosis of fetal aneuploidy by shotgun sequencing DNA from maternal blood. Proc Natl Acad Sci USA 2008;105:16266-71. [Abstract/Free Full Text]
    • (2008) Proc Natl Acad Sci USA , vol.105 , pp. 16266-16271
    • Fan, H.C.1    Blumenfeld, Y.J.2    Chitkara, U.3    Hudgins, L.4    Quake, S.R.5
  • 12
    • 0036140193 scopus 로고    scopus 로고
    • Differential DNA methylation between fetus and mother as a strategy for detecting fetal DNA in maternal plasma
    • Abstract/Free Full Text
    • Poon LLM, Leung TN, Lau TK, Chow KCK, Lo YMD. Differential DNA methylation between fetus and mother as a strategy for detecting fetal DNA in maternal plasma. Clin Chem 2002;48:35-41. [Abstract/Free Full Text]
    • (2002) Clin Chem , vol.48 , pp. 35-41
    • Poon, L.L.M.1    Leung, T.N.2    Lau, T.K.3    Chow, K.C.K.4    Lo, Y.M.D.5
  • 13
    • 0023936538 scopus 로고
    • Genetic disorders in children and young adults: A population study
    • Web of Science][Medline
    • Baird PA, Anderson TW, Newcombe HB, Lowry RB. Genetic disorders in children and young adults: a population study. Am J Hum Genet 1988;42:677-93.[Web of Science][Medline]
    • (1988) Am J Hum Genet , vol.42 , pp. 677-693
    • Baird, P.A.1    Anderson, T.W.2    Newcombe, H.B.3    Lowry, R.B.4
  • 14
    • 0034818672 scopus 로고    scopus 로고
    • Fetal sex determination from maternal plasma in pregnancies at risk for congenital adrenal hyperplasia
    • CrossRef, Web of Science][Medline
    • Rijnders RJP, van der Schoot CE, Bossers B, de Vroede MAMJ, Christiaens GCML. Fetal sex determination from maternal plasma in pregnancies at risk for congenital adrenal hyperplasia. Obstet Gynecol 2001;98:374-8.[CrossRef] [Web of Science][Medline]
    • (2001) Obstet Gynecol , vol.98 , pp. 374-378
    • Rijnders, R.J.P.1    van der Schoot, C.E.2    Bossers, B.3    de Vroede, M.A.M.J.4    Christiaens, G.C.M.L.5
  • 15
    • 39149099757 scopus 로고    scopus 로고
    • Non-invasive fetal sex determination: Impact on clinical practice
    • CrossRef][Web of Science][Medline
    • Finning KM, Chitty LS. Non-invasive fetal sex determination: impact on clinical practice. Semin Fetal Neonatal Med 2008;13:69-75.[CrossRef][Web of Science][Medline]
    • (2008) Semin Fetal Neonatal Med , vol.13 , pp. 69-75
    • Finning, K.M.1    Chitty, L.S.2
  • 17
    • 39149127946 scopus 로고    scopus 로고
    • Non-invasive prenatal diagnosis of single gene disorders: How close are we?
    • CrossRef][Web of Science][Medline
    • Norbury G, Norbury CJ. Non-invasive prenatal diagnosis of single gene disorders: how close are we? Semin Fetal Neonatal Med 2008;13:76-83.[CrossRef][Web of Science][Medline]
    • (2008) Semin Fetal Neonatal Med , vol.13 , pp. 76-83
    • Norbury, G.1    Norbury, C.J.2
  • 19
    • 33846449071 scopus 로고    scopus 로고
    • Non-invasive prenatal detection of achondroplasia in size-fractionated cell-free DNA by MALDI-TOF MS assay
    • CrossRef][Web of Science][Medline
    • Li Y, Paget-Christiaens LGC, Gille JJP, Holzgreve W. Non-invasive prenatal detection of achondroplasia in size-fractionated cell-free DNA by MALDI-TOF MS assay. Prenat Diagn 2007;27:11-7. [CrossRef][Web of Science][Medline]
    • (2007) Prenat Diagn , vol.27 , pp. 11-17
    • Li, Y.1    Paget-Christiaens, L.G.C.2    Gille, J.J.P.3    Holzgreve, W.4
  • 21
    • 58149401202 scopus 로고    scopus 로고
    • Lun FMF, Tsui NBY, Chan KCA, Leung TY, Lau TK, Charoenkwan P, et al. Noninvasive prenatal diagnosis of monogenic diseases by digital size selection and relative mutation dosage on DNA in maternal plasma. Proc Natl Acad Sci USA 2008;105:19920-5.[Abstract/Free Full Text]
    • Lun FMF, Tsui NBY, Chan KCA, Leung TY, Lau TK, Charoenkwan P, et al. Noninvasive prenatal diagnosis of monogenic diseases by digital size selection and relative mutation dosage on DNA in maternal plasma. Proc Natl Acad Sci USA 2008;105:19920-5.[Abstract/Free Full Text]
  • 22
    • 39149109269 scopus 로고    scopus 로고
    • Non-invasive prenatal diagnosis and determination of fetal Rh status
    • CrossRef][Web of Science][Medline
    • Van der Schoot CE, Hahn S, Chitty LS. Non-invasive prenatal diagnosis and determination of fetal Rh status. Semin Fetal Neonatal Med 2008;13:63-8.[CrossRef][Web of Science][Medline]
    • (2008) Semin Fetal Neonatal Med , vol.13 , pp. 63-68
    • Van der Schoot, C.E.1    Hahn, S.2    Chitty, L.S.3
  • 23
    • 0347898005 scopus 로고    scopus 로고
    • Quantitative analysis of fetal DNA in maternal plasma and serum; implications for noninvasive prenatal diagnosis
    • CrossRef][Web of Science][Medline
    • Lo YMD, Tein MSC, Lau TK, Haines CJ, Leung TN, Poon PMK, et al. Quantitative analysis of fetal DNA in maternal plasma and serum; implications for noninvasive prenatal diagnosis. Am J Hum Genet 1998;62:768-75. [CrossRef][Web of Science][Medline]
    • (1998) Am J Hum Genet , vol.62 , pp. 768-775
    • Lo, Y.M.D.1    Tein, M.S.C.2    Lau, T.K.3    Haines, C.J.4    Leung, T.N.5    Poon, P.M.K.6
  • 24
    • 35448967926 scopus 로고    scopus 로고
    • Fetal genotyping for the K (Kell) and Rh C, c, and E blood groups on cell-free fetal DNA in maternal plasma
    • CrossRef][Web of Science][Medline
    • Finning K, Martin P, Summers J, Daniels G. Fetal genotyping for the K (Kell) and Rh C, c, and E blood groups on cell-free fetal DNA in maternal plasma. Transfusion 2007;47:2126-33.[CrossRef][Web of Science][Medline]
    • (2007) Transfusion , vol.47 , pp. 2126-2133
    • Finning, K.1    Martin, P.2    Summers, J.3    Daniels, G.4
  • 25
    • 33846903851 scopus 로고    scopus 로고
    • Plasma placental RNA allelic ratio permits noninvasive prenatal chromosomal aneuploidy detection
    • CrossRef][Web of Science][Medline
    • Lo YMD, Tsui NBY, Chiu RWK, Lau TK, Leung TN, Heung MMS, et al. Plasma placental RNA allelic ratio permits noninvasive prenatal chromosomal aneuploidy detection. Nat Med 2007;13:218-23. [CrossRef][Web of Science][Medline]
    • (2007) Nat Med , vol.13 , pp. 218-223
    • Lo, Y.M.D.1    Tsui, N.B.Y.2    Chiu, R.W.K.3    Lau, T.K.4    Leung, T.N.5    Heung, M.M.S.6
  • 26
    • 58149490683 scopus 로고    scopus 로고
    • Chiu RW, Chan KC, Gao Y, Lau VY, Zheng W, Leung TY, et al. Noninvasive prenatal diagnosis of fetal chromosomal aneuploidy by massively parallel genomic sequencing of DNA in maternal plasma. Proc Natl Acad Sci USA 2008;105:20458-63.[Abstract/Free Full Text]
    • Chiu RW, Chan KC, Gao Y, Lau VY, Zheng W, Leung TY, et al. Noninvasive prenatal diagnosis of fetal chromosomal aneuploidy by massively parallel genomic sequencing of DNA in maternal plasma. Proc Natl Acad Sci USA 2008;105:20458-63.[Abstract/Free Full Text]
  • 27
    • 39149103375 scopus 로고    scopus 로고
    • Ethical aspects arising from non-invasive fetal diagnosis
    • CrossRef][Web of Science][Medline
    • Newson AJ. Ethical aspects arising from non-invasive fetal diagnosis. Semin Fetal Neonatal Med 2008;13:103-8.[CrossRef][Web of Science][Medline]
    • (2008) Semin Fetal Neonatal Med , vol.13 , pp. 103-108
    • Newson, A.J.1
  • 28
    • 70549105703 scopus 로고    scopus 로고
    • Will the introduction of non-invasive prenatal diagnostic testing erode informed choices? An experimental study of health care professionals
    • Epub ahead of print June 26
    • Van den Heuvel A, Chitty L, Dormandy E, Newson A, Deans Z, Attwood S, et al. Will the introduction of non-invasive prenatal diagnostic testing erode informed choices? An experimental study of health care professionals. Patient Educ Couns [Epub ahead of print 2009 June 26].
    • (2009) Patient Educ Couns
    • Van den Heuvel, A.1    Chitty, L.2    Dormandy, E.3    Newson, A.4    Deans, Z.5    Attwood, S.6
  • 29
    • 0002836620 scopus 로고
    • Principles and practice of screening for disease
    • Wilson J, Jungner G. Principles and practice of screening for disease. Public Health Papers 1968;34.
    • (1968) Public Health Papers , pp. 34
    • Wilson, J.1    Jungner, G.2
  • 30
    • 33746624393 scopus 로고    scopus 로고
    • Millions of missing girls: From fetal sexing to high technology sex selection in India
    • CrossRef, Web of Science][Medline
    • George SM. Millions of missing girls: from fetal sexing to high technology sex selection in India. Prenat Diagn 2006;26:604-9.[CrossRef] [Web of Science][Medline]
    • (2006) Prenat Diagn , vol.26 , pp. 604-609
    • George, S.M.1
  • 31
    • 33746645499 scopus 로고    scopus 로고
    • Attitudes to and practices regarding sex selection in China
    • CrossRef][Web of Science][Medline
    • Chan CL, Blyth E, Chan CH. Attitudes to and practices regarding sex selection in China. Prenat Diagn 2006;26:610-3.[CrossRef][Web of Science][Medline]
    • (2006) Prenat Diagn , vol.26 , pp. 610-613
    • Chan, C.L.1    Blyth, E.2    Chan, C.H.3
  • 32
    • 58049202879 scopus 로고    scopus 로고
    • The use of cell-free fetal nucleic acids in maternal blood for non-invasive prenatal diagnosis
    • Abstract/Free Full Text
    • Wright CF, Burton H. The use of cell-free fetal nucleic acids in maternal blood for non-invasive prenatal diagnosis. Hum Reprod Update 2009;15:139-51.[Abstract/Free Full Text]
    • (2009) Hum Reprod Update , vol.15 , pp. 139-151
    • Wright, C.F.1    Burton, H.2
  • 33
    • 66249100493 scopus 로고    scopus 로고
    • Cell-free fetal nucleic acids for non-invasive prenatal diagnosis
    • Cambridge: PHG Foundation
    • Wright C. Cell-free fetal nucleic acids for non-invasive prenatal diagnosis. Report of the UK expert working group. Cambridge: PHG Foundation, 2009.
    • (2009) Report of the UK expert working group
    • Wright, C.1


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