MALDI-TOF mass spectrometry compared with real-time PCR for detection of fetal cell-free DNA in maternal plasma [7]

Clinical Chemistry

Volumn 52, Issue 12, 2006, Pages 2311-2312

  Li, Ying ^a   Holzgreve, Wolfgang ^a   Kiefer, Vivian ^a   Hahn, Sinuhe ^a  

^a UNIVERSITY WOMEN S HOSPITAL   (Switzerland)

Author keywords

[No Author keywords available]

Indexed keywords

DNA; PRIMER DNA;

ACCURACY; BASE PAIRING; DNA DETERMINATION; FEMALE; GENE SEQUENCE; HUMAN; HUMAN TISSUE; INTERMETHOD COMPARISON; LETTER; MATERNAL PLASMA; MATRIX ASSISTED LASER DESORPTION IONIZATION TIME OF FLIGHT MASS SPECTROMETRY; REAL TIME POLYMERASE CHAIN REACTION; SCORING SYSTEM; SENSITIVITY AND SPECIFICITY; SEQUENCE ANALYSIS; SINGLE NUCLEOTIDE POLYMORPHISM; SRY GENE;

DNA; FALSE NEGATIVE REACTIONS; FEMALE; FETUS; HUMANS; PLASMA; POLYMERASE CHAIN REACTION; PREGNANCY; SEX-DETERMINING REGION Y PROTEIN; SPECTROMETRY, MASS, MATRIX-ASSISTED LASER DESORPTION-IONIZATION;

EID: 33845539572     PISSN: 00099147     EISSN: None     Source Type: Journal    
DOI: 10.1373/clinchem.2006.076257     Document Type: Letter

References (5)

1. Gut IG. DNA analysis by MALDI-TOF mass spectrometry. Hum Mutat 2004;23:437-41.
2. Ding C, Chiu RW, Lau TK, Leung TN, Chan LC, Chan AY, et al. MS analysis of single-nucleotide differences in circulating nucleic acids: application to noninvasive prenatal diagnosis. Proc Natl Acad Sci USA 2004;101:10762-7.
3. Li Y, Hahn D, Holzgreve W, Hahn S. Ready detection of donor-specific single-nucleotide polymorphisms in the urine of renal transplant recipients by matrix-assisted laser desorption/ionization time-of-flight mass spectrometry. Clin Chem 2005;51:1903-4.
4. Li Y, Zimmermann B, Rusterholz C, Kang A, Holzgreve W, Hahn S. Size separation of circulatory DNA in maternal plasma permits ready detection of fetal DNA polymorphisms. Clin Chem 2004;50:1002-11.
5. Huang DJ, Zimmermann BG, Holzgreve W, Hahn S. Use of an automated method improves the yield and quality of cell-free fetal DNA extracted from maternal plasma. Clin Chem 2005;51: 2419-20.